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30 Results Found

  • Article
  • Open Access
14 Citations
2,636 Views
11 Pages

Variation in a Newly Identified Caprine KRTAP Gene Is Associated with Raw Cashmere Fiber Weight in Longdong Cashmere Goats

  • Mengli Zhao,
  • Huitong Zhou,
  • Yuzhu Luo,
  • Jiqing Wang,
  • Jiang Hu,
  • Xiu Liu,
  • Shaobin Li,
  • Kaiwen Zhang,
  • Huimin Zhen and
  • Jon G. H. Hickford

22 April 2021

Keratin-associated proteins (KAPs) and keratins determine the physical and chemical properties of cashmere fibers as they are the main components of the fibers. It has been reported that ovine KRTAP1-2 affects clean fleece weight, greasy fleece weigh...

  • Article
  • Open Access
21 Citations
4,224 Views
11 Pages

Identification of Ovine KRTAP28-1 and Its Association with Wool Fibre Diameter

  • Lingrong Bai,
  • Jing Wang,
  • Huitong Zhou,
  • Hua Gong,
  • Jinzhong Tao and
  • Jon G. H. Hickford

2 April 2019

Keratin-associated proteins (KAPs) are a diverse group of proteins and form a matrix that cross-links keratin intermediate filaments in hair and wool fibres. From over 100 KAP genes (KRTAPs) identified in mammalian species, KRTAP25-1 is a high sulphu...

  • Article
  • Open Access
33 Citations
4,509 Views
9 Pages

Variation in the Ovine KAP6-3 Gene (KRTAP6-3) Is Associated with Variation in Mean Fibre Diameter-Associated Wool Traits

  • Shaobin Li,
  • Huitong Zhou,
  • Hua Gong,
  • Fangfang Zhao,
  • Jiqing Wang,
  • Yuzhu Luo and
  • Jon G. H. Hickford

18 August 2017

Polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) analysis was used to investigate variation in the ovine KAP6-3 gene (KRTAP6-3) in 383 Merino × Southdown-cross lambs from four sire-lines, and to determine whether this...

  • Article
  • Open Access
7 Citations
3,341 Views
9 Pages

Major Histocompatibility Complex (MHC) Diversity of the Reintroduction Populations of Endangered Przewalski’s Horse

  • Yongqing Tang,
  • Gang Liu,
  • Shasha Zhao,
  • Kai Li,
  • Dong Zhang,
  • Shuqiang Liu and
  • Defu Hu

23 May 2022

Major histocompatibility complex (MHC) genes are the most polymorphic in vertebrates and the high variability in many MHC genes is thought to play a crucial role in pathogen recognition. The MHC class II locus DQA polymorphism was analyzed in the end...

  • Article
  • Open Access
31 Citations
5,772 Views
12 Pages

Identification of the Caprine Keratin-Associated Protein 20-2 (KAP20-2) Gene and Its Effect on Cashmere Traits

  • Jiqing Wang,
  • Longjie Che,
  • Jon G. H. Hickford,
  • Huitong Zhou,
  • Zhiyun Hao,
  • Yuzhu Luo,
  • Jiang Hu,
  • Xiu Liu and
  • Shaobin Li

17 November 2017

The gene encoding the high glycine/tyrosine keratin-associated protein 20-2 (KAP20-2) gene has been described in humans, but has not been identified in any livestock species. A search for similar sequences in the caprine genome using the human KAP20-...

  • Article
  • Open Access
46 Citations
5,719 Views
9 Pages

Identification of the Ovine Keratin-Associated Protein 22-1 (KAP22-1) Gene and Its Effect on Wool Traits

  • Shaobin Li,
  • Huitong Zhou,
  • Hua Gong,
  • Fangfang Zhao,
  • Jiqing Wang,
  • Xiu Liu,
  • Yuzhu Luo and
  • Jon G. H. Hickford

11 January 2017

Keratin-associated proteins (KAPs) are structural components of wool and hair fibers. To date, eight high glycine/tyrosine KAP (HGT-KAP) families have been identified in humans, but only three have been identified in sheep. In this study, the putativ...

  • Article
  • Open Access
19 Citations
3,216 Views
11 Pages

Variation in the Caprine Keratin-Associated Protein 27-1 Gene is Associated with Cashmere Fiber Diameter

  • Mengli Zhao,
  • Huitong Zhou,
  • Yuzhu Luo,
  • Jiqing Wang,
  • Jiang Hu,
  • Xiu Liu,
  • Shaobin Li,
  • Zhiyun Hao,
  • Xiayang Jin and
  • Jon G. H. Hickford
  • + 3 authors

13 August 2020

Variation in some caprine keratin-associated protein (KAP) genes has been associated with cashmere fiber traits, but many KAP genes remain unidentified in goats. In this study, we confirm the identification of a KAP27-1 gene (KRTAP27-1) and describe...

  • Article
  • Open Access
11 Citations
3,360 Views
9 Pages

Variation in the Lipin 1 Gene Is Associated with Birth Weight and Selected Carcass Traits in New Zealand Romney Sheep

  • Guan Wang,
  • Huitong Zhou,
  • Hua Gong,
  • Jianning He,
  • Yuzhu Luo,
  • Jon G. H. Hickford,
  • Jiang Hu,
  • Jiqing Wang,
  • Xiu Liu and
  • Shaobin Li

3 February 2020

Lipin 1 plays an important role in lipid metabolism. In this study; we searched for variation in the ovine lipin 1 gene (LPIN1) in three gene regions (a 5′ non-coding region; a region containing an alternatively spliced exon in intron 4; and a...

  • Article
  • Open Access
2 Citations
2,955 Views
8 Pages

Ovine Toll-like Receptor 9 (TLR9) Gene Variation and Its Association with Flystrike Susceptibility

  • Xiu Liu,
  • Huitong Zhou,
  • Hua Gong,
  • Wenting Liu,
  • Qian Fang,
  • Yuzhu Luo,
  • Jiqing Wang,
  • Shaobin Li,
  • Jiang Hu and
  • Jonathan G. H. Hickford

14 December 2021

Toll-like receptors (TLRs) are a family of proteins that play a role in innate immune responses by recognising pathogen-associated molecular patterns derived from various microbes. Of these receptors, TLR9 recognises bacterial and viral DNA containin...

  • Article
  • Open Access
7 Citations
2,721 Views
13 Pages

Identification of the Ovine Keratin-Associated Protein 2-1 Gene and Its Sequence Variation in Four Chinese Sheep Breeds

  • Jianqing Wang,
  • Huitong Zhou,
  • Jon G. H. Hickford,
  • Yuzhu Luo,
  • Hua Gong,
  • Jiang Hu,
  • Xiu Liu,
  • Shaobin Li,
  • Yize Song and
  • Jiqing Wang
  • + 2 authors

29 May 2020

Keratin-associated proteins are important components of wool fibers. The gene encoding the high-sulfur keratin-associated protein 2-1 has been described in humans, but it has not been described in sheep. A basic local alignment search tool nucleotide...

  • Article
  • Open Access
13 Citations
4,526 Views
11 Pages

Novel Point Mutations in the NKX2.5 Gene in Pediatric Patients with Non-Familial Congenital Heart Disease

  • Mehri Khatami,
  • Mansoureh Mazidi,
  • Shabnam Taher,
  • Mohammad Mehdi Heidari and
  • Mehdi Hadadzadeh

Background and objective: Congenital heart disease (CHD) is the most common birth abnormality in the structure or function of the heart that affects approximately 1% of all newborns. Despite its prevalence and clinical importance, the etiology of CHD...

  • Article
  • Open Access
6 Citations
3,786 Views
10 Pages

Expression and Variations in EPAS1 Associated with Oxygen Metabolism in Sheep

  • Qiming Xi,
  • Fangfang Zhao,
  • Jiang Hu,
  • Jiqing Wang,
  • Xiu Liu,
  • Pengju Dang,
  • Yuzhu Luo and
  • Shaobin Li

15 October 2022

Endothelial PAS domain protein 1 gene (EPAS1) is a member of the HIF gene family. This gene encodes a transcription factor subunit that is involved in the induction of oxygen-regulated genes. Several studies have demonstrated that a mutation in EPAS1...

  • Article
  • Open Access
22 Citations
4,384 Views
18 Pages

18 December 2019

Myostatin acts as a negative regulator of muscle growth; therefore, its role is important with regard to animal growth and meat production. This study was undertaken with the objective to detect polymorphisms in the first intron and c.*1232 position...

  • Article
  • Open Access
8 Citations
2,017 Views
11 Pages

Ovine KRTAP36-2: A New Keratin-Associated Protein Gene Related to Variation in Wool Yield

  • Huitong Zhou,
  • Wenhao Li,
  • Lingrong Bai,
  • Jiqing Wang,
  • Yuzhu Luo,
  • Shaobin Li and
  • Jonathan G. H. Hickford

6 November 2023

Keratin-associated proteins (KAPs) are structural components of wool fibres. High-glycine/tyrosine (HGT)-KAPs are a subset of the KAP family, and their abundance in fibres varies. In this study, we report the discovery of an ovine HGT-KAP gene to whi...

  • Article
  • Open Access
16 Citations
6,407 Views
14 Pages

7 January 2014

Primers based on the cDNA sequence of the goose growth hormone (GH) gene in GenBank were designed to amplify exon 2 of the GH gene in Huoyan goose. A total of 552 individuals were brooded in one batch and raised in Liaoning and Jiangsu Provinces, Chi...

  • Article
  • Open Access
6 Citations
2,184 Views
11 Pages

Sequence Variation in Caprine KRTAP6-2 Affects Cashmere Fiber Diameter

  • Jian Cao,
  • Jiqing Wang,
  • Huitong Zhou,
  • Jiang Hu,
  • Xiu Liu,
  • Shaobin Li,
  • Yuzhu Luo and
  • Jon G. H. Hickford

11 August 2022

Keratin-associated proteins (KAPs) are a structural component of cashmere fibers and in part determine fiber attributes. The gene encoding the high-glycine/tyrosine KAP6-2 (called KRTAP6-2) has been described in sheep, but it has not been identified...

  • Article
  • Open Access
3 Citations
4,481 Views
12 Pages

New Method for Differentiation of Granuloviruses (Betabaculoviruses) Based on Multitemperature Single Stranded Conformational Polymorphism

  • Martyna Krejmer-Rabalska,
  • Lukasz Rabalski,
  • Marlinda Lobo de Souza,
  • Sean D. Moore and
  • Boguslaw Szewczyk

Baculoviruses have been used as biopesticides for decades. Recently, due to the excessive use of chemical pesticides there is a need for finding new agents that may be useful in biological protection. Sometimes few isolates or species are discovered...

  • Review
  • Open Access
234 Citations
36,496 Views
30 Pages

Food Waste Composting and Microbial Community Structure Profiling

  • Kishneth Palaniveloo,
  • Muhammad Azri Amran,
  • Nur Azeyanti Norhashim,
  • Nuradilla Mohamad-Fauzi,
  • Fang Peng-Hui,
  • Low Hui-Wen,
  • Yap Kai-Lin,
  • Looi Jiale,
  • Melissa Goh Chian-Yee and
  • Shariza Abdul Razak
  • + 2 authors

22 June 2020

Over the last decade, food waste has been one of the major issues globally as it brings a negative impact on the environment and health. Rotting discharges methane, causing greenhouse effect and adverse health effects due to pathogenic microorganisms...

  • Article
  • Open Access
6 Citations
3,287 Views
10 Pages

Associations between the Bovine Myostatin Gene and Milk Fatty Acid Composition in New Zealand Holstein-Friesian × Jersey-Cross Cows

  • Ishaku L. Haruna,
  • Yunhai Li,
  • Ugonna J. Ekegbu,
  • Hamed Amirpour-Najafabadi,
  • Huitong Zhou and
  • Jon G. H. Hickford

19 August 2020

The myostatin gene (MSTN), which encodes the protein myostatin, is pleiotropic, and its expression has been associated with both increased and decreased adipogenesis and increased skeletal muscle mass in animals. In this study, the polymerase chain r...

  • Article
  • Open Access
474 Views
9 Pages

23 September 2025

The keratin-associated proteins (KAPs) are a class of wool proteins. They form a matrix that cross-links the wool intermediate filament keratins. The KAPs are thought to affect wool fibre structure and properties and have been associated with variati...

  • Article
  • Open Access
33 Citations
4,102 Views
12 Pages

Variation in the Caprine KAP24-1 Gene Affects Cashmere Fibre Diameter

  • Jiqing Wang,
  • Huitong Zhou,
  • Yuzhu Luo,
  • Mengli Zhao,
  • Hua Gong,
  • Zhiyun Hao,
  • Jiang Hu and
  • Jon G.H. Hickford

5 January 2019

The keratin-associated proteins (KAPs) are structural components of cashmere fibres. The gene encoding the high-sulphur (HS)-KAP24-1 (KRTAP24-1) has been identified in humans and sheep, but it has not been described in goats. In this study, we report...

  • Article
  • Open Access
16 Citations
3,245 Views
14 Pages

Predominance and Diversity of GLRaV-3 in Native Vines of Mediterranean Croatia

  • Katarina Hančević,
  • Pasquale Saldarelli,
  • Mate Čarija,
  • Silvija Černi,
  • Goran Zdunić,
  • Ana Mucalo and
  • Tomislav Radić

24 December 2020

Sixteen grapevine cultivars from Mediterranean Croatia were surveyed for the presence of 10 of the most economically important grapevine viruses. The presence of Grapevine fanleaf virus (GFLV), Arabis mosaic virus (ArMV), Grapevine leafroll associate...

  • Article
  • Open Access
16 Citations
3,048 Views
12 Pages

Identification of Caprine KRTAP28-1 and Its Effect on Cashmere Fiber Diameter

  • Jiqing Wang,
  • Huitong Zhou,
  • Jon G. H. Hickford,
  • Mengli Zhao,
  • Hua Gong,
  • Zhiyun Hao,
  • Jiyuan Shen,
  • Jiang Hu,
  • Xiu Liu and
  • Yuzhu Luo
  • + 1 author

22 January 2020

The keratin-associated proteins (KAPs) are constituents of cashmere fibers and variation in many KAP genes (KRTAPs) has been found to be associated with fiber traits. The gene encoding the high-sulphur KAP28-1 has been described in sheep, but it has...

  • Article
  • Open Access
11 Citations
5,261 Views
12 Pages

30 March 2018

Uncoupling protein-1 gene (UCP1) plays an important role in the regulation of thermogenesis, energy expenditure, and protection against oxidative stress. In this study, six separate UCP1 regions: region-1 and region-2 (two parts of the promoter), reg...

  • Article
  • Open Access
13 Citations
3,700 Views
13 Pages

Prevalence of Virus Infections and GLRaV-3 Genetic Diversity in Selected Clones of Croatian Indigenous Grapevine Cultivar Plavac Mali

  • Mate Čarija,
  • Tomislav Radić,
  • Silvija Černi,
  • Ana Mucalo,
  • Goran Zdunić,
  • Darko Vončina,
  • Martin Jagunić and
  • Katarina Hančević

27 January 2022

The cultivar Plavac Mali (Vitis vinifera L.), the most important indigenous red grapevine cultivar in Croatia, was tested for the presence of 16 grapevine viruses. Thirty-five samples from the collection vineyard were tested for the presence of grape...

  • Article
  • Open Access
26 Citations
4,254 Views
16 Pages

Association of GHR Polymorphisms with Milk Production in Buffaloes

  • Shymaa M. El-Komy,
  • Ayman A. Saleh,
  • Tamer M. Abdel-Hamid and
  • Mohammed A. El-Magd

15 July 2020

For its role in the mediation of growth hormone (GH) galactopoietic effect, growth hormone receptor (GHR) was considered a functional candidate gene for milk performance in cattle. However, its genetic variation and potential effect have not been inv...

  • Article
  • Open Access
31 Citations
4,029 Views
10 Pages

The Mean Staple Length of Wool Fibre Is Associated with Variation in the Ovine Keratin-Associated Protein 21-2 Gene

  • Shaobin Li,
  • Huitong Zhou,
  • Hua Gong,
  • Fangfang Zhao,
  • Jiqing Wang,
  • Xiu Liu,
  • Jiang Hu,
  • Yuzhu Luo and
  • Jon G.H. Hickford

30 January 2020

Wool and hair fibres consist of a variety of proteins, including the keratin-associated proteins (KAPs). In this study, a putative ovine homologue of the human KAP21-2 gene (KRTAP21-2) was identified. It was located on chromosome 1 as a 201-bp open r...

  • Article
  • Open Access
1,001 Views
14 Pages

19 June 2025

Background: Cashmere is one of the important economic products of goats, and the KRTAP gene family, as an important family of regulatory genes in the growth process of cashmere fiber, largely affects the quality of cashmere. Methods: In this study, t...

  • Article
  • Open Access
4 Citations
2,538 Views
13 Pages

Identification of the Keratin-Associated Protein 22-2 Gene in the Capra hircus and Association of Its Variation with Cashmere Traits

  • Zhanzhao Chen,
  • Jian Cao,
  • Fangfang Zhao,
  • Zhaohua He,
  • Hongxian Sun,
  • Jiqing Wang,
  • Xiu Liu and
  • Shaobin Li

4 September 2023

The Cashmere goat is an excellent local goat breed in Gansu Province of China, and it is expected to improve cashmere production and cashmere quality through selection and breeding to enhance its commercial value. Keratin-associated proteins (KAPs) p...

  • Article
  • Open Access
21 Citations
5,114 Views
10 Pages

Variation in the Fatty Acid Synthase Gene (FASN) and Its Association with Milk Traits in Gannan Yaks

  • Bingang Shi,
  • Yanyan Jiang,
  • Yanli Chen,
  • Zhidong Zhao,
  • Huitong Zhou,
  • Yuzhu Luo,
  • Jiang Hu and
  • Jon G.H. Hickford

27 August 2019

Fatty acid synthase (FASN) is an enzyme involved in the synthesis of fatty acids (FA) and plays a central role in de novo lipogenesis in mammals. This study was conducted to ascertain the relative level of expression of the FASN gene (FASN) in tissue...