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22 Results Found

  • Case Report
  • Open Access
5 Citations
6,944 Views
13 Pages

Takayasu’s Arteritis: A Special Case Report and Review of the Literature

  • Paloma Moisii,
  • Irina Jari,
  • Alexandru Gratian Naum,
  • Doina Butcovan and
  • Grigore Tinica

9 March 2024

Background: Takayasu’s arteritis is a rare type of vasculitis with severe complications like stroke, ischemic heart disease, pulmonary hypertension, secondary hypertension, and aneurysms. Diagnosis is achieved using clinical and angiographic cr...

  • Article
  • Open Access
1 Citations
2,528 Views
13 Pages

Pathological Mechanisms and Additional Factors Involved in Complex Neck Traumatology

  • Diana Bulgaru-Iliescu,
  • Andrei Nicolau,
  • Ștefan Roșca,
  • Ioan-Adrian Ciureanu and
  • Florentina Severin

14 December 2021

Background. Cervical trauma can be closed or open, have different degrees of severity, incidence rates, prevalence, or mortality, with variations in the presence of demographic factors. The different types of traumatic injuries have a certain pattern...

  • Article
  • Open Access
2 Citations
4,620 Views
8 Pages

Cardio Protective Effects of Lipid Emulsion against Ropivacaine-Induced Local Anesthetic Systemic Toxicity—An Experimental Study

  • Alexandra Elena Lazar,
  • Simona Gurzu,
  • Attila Kovecsi,
  • Marcel Perian,
  • Bogdan Cordos,
  • Mircea Constantin Gherghinescu and
  • Liviu Sorin Enache

15 May 2022

Inadvertent intravascular injection of local anesthetics (LA) during regional anesthesia causes Local Anesthetic Systemic Toxicity (LAST). Theories of lipid rescue in the case of LAST proved that the administration of lipids in LAST has beneficial ef...

  • Article
  • Open Access
9 Citations
5,245 Views
15 Pages

The Influence of SARS-CoV-2 Pandemic in the Diagnosis and Treatment of Cervical Dysplasia

  • Anca-Maria Istrate-Ofițeru,
  • Elena-Iuliana-Anamaria Berbecaru,
  • Dan Ruican,
  • Rodica Daniela Nagy,
  • Cătălina Rămescu,
  • Gabriela-Camelia Roșu,
  • Larisa Iovan,
  • Laurențiu Mihai Dîră,
  • George-Lucian Zorilă and
  • Maria-Loredana Țieranu
  • + 1 author

14 October 2021

Background and objectives. The risk of developing invasive cancer increased during the COVID-19 pandemic, especially in Romania, where the incidence of this disease is high due to limited medical education and broad screening. This study’s objective...

  • Article
  • Open Access
1 Citations
2,259 Views
20 Pages

A Histopathological and Surgical Analysis of Gastric Cancer: A Two-Year Experience in a Single Center

  • Cătălin Prodan-Bărbulescu,
  • Flaviu Ionuț Faur,
  • Norberth-Istvan Varga,
  • Rami Hajjar,
  • Paul Pașca,
  • Laura-Andreea Ghenciu,
  • Cătălin Ionuț Vlăduț Feier,
  • Alis Dema,
  • Naomi Fărcuț and
  • Sorin Bolintineanu
  • + 3 authors

2 July 2025

Background: Gastric neoplasms remain pathologies of the malignant spectrum with high incidence and prevalence, with their management requiring a precise histopathological characterization for optimal treatment planning. Methods: The present study is...

  • Case Report
  • Open Access
1 Citations
3,316 Views
9 Pages

Surgical, Dermatological and Morphopathological Considerations in the Diagnosis and Treatment of Cutaneous Lymphoproliferative Tumors, Primary CD4+

  • Valeriu Ardeleanu,
  • Lavinia-Alexandra Moroianu,
  • Anca Sava,
  • Tiberiu Tebeica,
  • Radu Cristian Jecan,
  • Marius Moroianu and
  • Alin Laurentiu Tatu

10 November 2022

Primary cutaneous lymphomas are a heterogeneous group of T-cell (CTCL) and B-cell lymphomas (CBCL) developing in the skin and without signs of extracutaneous disease at the time of diagnosis. The term “primary small/medium CD4+ T-cell lymphoma&...

  • Article
  • Open Access
2 Citations
1,751 Views
16 Pages

HPV and Other Risk Factors Involved in Pharyngeal Neoplasm—Clinical and Morphopathological Correlations in the Southwestern Region of Romania

  • Carmen Aurelia Mogoantă,
  • Mircea Sorin Ciolofan,
  • Anca-Maria Istrate-Ofițeru,
  • Stelian-Ștefăniță Mogoantă,
  • Gabriela-Camelia Roșu,
  • Florin Anghelina,
  • Alina-Nicoleta Căpitanescu,
  • Ioana Cristina Opriscan,
  • Nina Ionovici and
  • Mihaela Roxana Mitroi
  • + 2 authors

Oropharyngeal squamous cell carcinoma (OPSCC) development is strongly associated with risk factors like smoking, chronic alcohol consumption, and the living environment, but also chronic human papilloma virus (HPV) infection, which can trigger cascad...

  • Article
  • Open Access
13 Citations
137,010 Views
13 Pages

Analysis of XX SRY-Negative Sex Reversal Dogs

  • Sara Albarella,
  • Lisa De Lorenzi,
  • Elena Rossi,
  • Francesco Prisco,
  • Marita Georgia Riccardi,
  • Brunella Restucci,
  • Francesca Ciotola and
  • Pietro Parma

16 September 2020

Impaired fertility associated with disorders of sex development (DSDs) due to genetic causes in dogs are more and more frequently reported. Affected dogs are usually of specific breeds thus representing a cause of economic losses for breeders. The ai...

  • Article
  • Open Access
1 Citations
2,668 Views
11 Pages

Methylene Blue and Proflavine as Intraarterial Marker for Functional Perforazome—Comparative Study

  • Maria-Eliza Nedu,
  • Mihaela Tertis,
  • Cecilia Cristea and
  • Alexandru Valentin Georgescu

19 February 2021

Methylene blue (MB) is both a dye and a medicine known and used for a long time including as lymphatic tracer in melanoma and breast cancer for revealing sentinel lymph nodes. Proflavine (PRO) is an acriflavine dye, used as bacteriostatic disinfectan...

  • Article
  • Open Access
11 Citations
9,932 Views
10 Pages

Cytogenetic Analyses in Ewes with Congenital Abnormalities of the Genital Apparatus

  • Sara Albarella,
  • Emanuele D’Anza,
  • Giacomo Galdiero,
  • Luigi Esposito,
  • Davide De Biase,
  • Orlando Paciello,
  • Francesca Ciotola and
  • Vincenzo Peretti

10 October 2019

The Disorders of Sex Development (DSDs) are congenital conditions characterized by inconsistency among chromosomal, gonadal, and anatomical sex development. The aim of this research is to report the clinical and cytogenetic findings of four DSD cases...

  • Perspective
  • Open Access
8 Citations
3,759 Views
11 Pages

Though complexity science and chaos theory have become a common scientific divulgation theme, medical disciplines, and pathology in particular, still rely on a deterministic, reductionistic approach and still hesitate to fully appreciate the intrinsi...

  • Article
  • Open Access
7 Citations
3,382 Views
16 Pages

Identification and Characterization of New Seedborne Pathogens in Phaseolus vulgaris Landraces of Southern Italy

  • Eliana Dell’Olmo,
  • Massimo Zaccardelli,
  • Boris Basile,
  • Giandomenico Corrado and
  • Loredana Sigillo

9 January 2023

The diagnostic survey of seedborne fungal pathogens is fundamental for symptomless material stored in gene banks to avoid the diffusion of pathogens by germplasm distribution and propagation. In this work, seeds of Southern Italian landraces of the c...

  • Article
  • Open Access
10 Citations
4,209 Views
15 Pages

The Teleost Thymus in Health and Disease: New Insights from Transcriptomic and Histopathological Analyses of Turbot, Scophthalmus maximus

  • Paolo Ronza,
  • Diego Robledo,
  • Ana Paula Losada,
  • Roberto Bermúdez,
  • Belén G. Pardo,
  • Paulino Martínez and
  • María Isabel Quiroga

13 August 2020

The thymus is a primary lymphoid organ that plays a pivotal role in the adaptive immune system. The immunobiology of the thymus in fish is considered to be similar to that of mammals, but it is actually poorly characterized in several cultured teleos...

  • Article
  • Open Access
7 Citations
2,898 Views
12 Pages

Per- and polyfluoroalkyl substances can be referred to as the most critical group of contaminants of emerging concern. They can accumulate in high concentration in the kidney and are known to potentially affect its function. Nonetheless, there is a l...

  • Article
  • Open Access
7 Citations
4,533 Views
13 Pages

14 October 2024

Background: High-Intensity Laser (HIL) therapy, known for its biostimulatory effects on nerve cell growth and repair, shows promise for improving motor deficits caused by morphopathological changes. This research study aimed to comprehensively assess...

  • Article
  • Open Access
7 Citations
3,010 Views
11 Pages

Histopathological Lung Findings in COVID-19 B.1.617.2 SARS-CoV-2 Delta Variant

  • Ionuț Isaia Jeican,
  • Patricia Inișca,
  • Dan Gheban,
  • Vlad Anton,
  • Mihaela Lazăr,
  • Mihaela Laura Vică,
  • Daniela Mironescu,
  • Codrin Rebeleanu,
  • Carmen Bianca Crivii and
  • Maria Aluaș
  • + 2 authors

31 January 2023

Background: The Delta variant (Pango lineage B.1.617.2) is one of the most significant and aggressive variants of SARS-CoV-2. To the best of our knowledge, this is the first paper specifically studying pulmonary morphopathology in COVID-19 caused by...

  • Article
  • Open Access
17 Citations
3,231 Views
11 Pages

Hepatotoxicity in Patients with Hepatocellular Carcinoma on Treatment with Immune Checkpoint Inhibitors

  • Nicola Personeni,
  • Tiziana Pressiani,
  • Antonio D’Alessio,
  • Maria Giuseppina Prete,
  • Silvia Bozzarelli,
  • Luigi Terracciano,
  • Arianna Dal Buono,
  • Antonio Capogreco,
  • Alessio Aghemo and
  • Ana Lleo
  • + 6 authors

12 November 2021

Risk factors for hepatic immune-related adverse events (HIRAEs) in patients with advanced/unresectable hepatocellular carcinoma (HCC) treated with immune checkpoint inhibitors (ICIs) are unclear. We investigated: (i) clinical and morpho-pathological...

  • Article
  • Open Access
15 Citations
6,652 Views
21 Pages

Intramuscular Ricin Poisoning of Mice Leads to Widespread Damage in the Heart, Spleen, and Bone Marrow

  • Anita Sapoznikov,
  • Amir Rosner,
  • Reut Falach,
  • Yoav Gal,
  • Moshe Aftalion,
  • Yentl Evgy,
  • Ofir Israeli,
  • Tamar Sabo and
  • Chanoch Kronman

16 June 2019

Ricin, a lethal toxin derived from castor oil beans, is a potential bio-threat due to its high availability and simplicity of preparation. Ricin is prepared according to simple recipes available on the internet, and was recently considered in terrori...

  • Article
  • Open Access
2,229 Views
10 Pages

Peritoneal Dialysis-Induced Encapsulating Peritonitis: Diagnostic and Therapeutic Challenges in Women with Benign Gynecological Pathology

  • Cristian Iorga,
  • Cristina Raluca Iorga,
  • Iuliana Andreiana,
  • Simona Hildegard Stancu,
  • Traian Constantin and
  • Victor Strambu

15 May 2024

Background: Peritoneal sclerosis (PS) and its most severe form, encapsulating PS (EPS), are rare entities that can occur in various procedures (liver transplantation, intraperitoneal chemotherapy) or secondary to medications (beta-blockers); however,...

  • Article
  • Open Access
23 Citations
7,140 Views
19 Pages

Exposure to Iron Oxide Nanoparticles Coated with Phospholipid-Based Polymeric Micelles Induces Biochemical and Histopathological Pulmonary Changes in Mice

  • Mihaela Radu,
  • Ioana Mihaela Din,
  • Anca Hermenean,
  • Otilia Ludmila Cinteză,
  • Radu Burlacu,
  • Aurel Ardelean and
  • Anca Dinischiotu

10 December 2015

The biochemical and histopathological changes induced by the exposure to iron oxide nanoparticles coated with phospholipid-based polymeric micelles (IONPs-PM) in CD-1 mice lungs were analyzed. After 2, 3, 7 and 14 days following the intravenous injec...

  • Review
  • Open Access
1,112 Views
19 Pages

Reovirus Infections in Broiler Chickens: A Narrative Review

  • George-Andrei Călugărița,
  • Iasmina Luca,
  • Radu-Valentin Gros,
  • Tudor-Mihai Căsălean,
  • Alexandru Gavrilă and
  • Adrian Stancu

22 October 2025

Infections caused by avian orthoreovirus represent an emerging problem with a major impact on the global poultry industry, especially in the intensive rearing of broilers. This article addresses, in a complex manner, the etiology of some clinical syn...

  • Systematic Review
  • Open Access
15 Citations
4,024 Views
15 Pages

A Systematic Review of Lung Autopsy Findings in Elderly Patients after SARS-CoV-2 Infection

  • Susa Septimiu-Radu,
  • Tejaswi Gadela,
  • Doros Gabriela,
  • Cristian Oancea,
  • Ovidiu Rosca,
  • Voichita Elena Lazureanu,
  • Roxana Manuela Fericean,
  • Felix Bratosin,
  • Andreea Dumitrescu and
  • Emil Robert Stoicescu
  • + 3 authors

6 March 2023

Although COVID-19 may cause various and multiorgan diseases, few research studies have examined the postmortem pathological findings of SARS-CoV-2-infected individuals who died. Active autopsy results may be crucial for understanding how COVID-19 inf...