You are currently on the new version of our website. Access the old version .

26 Results Found

  • Article
  • Open Access
20 Citations
5,773 Views

Cow Milk Lactoferrin Possesses Several Catalytic Activities

  • Svetlana E. Soboleva,
  • Sergey E. Sedykh,
  • Ludmila I. Alinovskaya,
  • Valentina N. Buneva and
  • Georgy A. Nevinsky

Lactoferrin (LF) is a Fe3+-binding glycoprotein, that was first recognized in milk and then in other epithelial secretions and barrier body fluids to which many different functions have been attributed to LF including protection from iron-induced lip...

  • Article
  • Open Access
4 Citations
3,899 Views
17 Pages

Further Insights into the Gut Microbiota of Cow’s Milk Allergic Infants: Analysis of Microbial Functionality and Its Correlation with Three Fecal Biomarkers

  • Elisa Zubeldia-Varela,
  • Tomás Clive Barker-Tejeda,
  • Leticia Mera-Berriatua,
  • Raphaëlle Bazire,
  • Paula Cabrera-Freitag,
  • Carles Ubeda,
  • Domingo Barber,
  • María Pilar Francino,
  • David Rojo and
  • Marina Pérez-Gordo

Cow’s milk allergy (CMA) is one of the most prevalent food allergies in children. Several studies have demonstrated that gut microbiota influences the acquisition of oral tolerance to food antigens at initial stages of life. Changes in the gut...

  • Article
  • Open Access
6 Citations
7,731 Views
10 Pages

Effects of a Bovine Lactoferrin Formulation from Cow’s Milk on Menstrual Distress in Volunteers: A Randomized, Crossover Study

  • Hiroshi M. Ueno,
  • Ran Emilie Yoshise,
  • Tomohiro Sugino,
  • Osami Kajimoto and
  • Toshiya Kobayashi

Dysmenorrhea is a highly prevalent complaint and highly undiagnosed gynecologic condition. Dairy products have a potential in the management of menstrual distress, and bovine lactoferrin can help the subjective dysphoria associated with dysmenorrhea....

  • Article
  • Open Access
38 Citations
15,133 Views
20 Pages

Determination of Lactoferrin and Immunoglobulin G in Animal Milks by New Immunosensors

  • Luigi Campanella,
  • Elisabetta Martini,
  • Manuela Pintore and
  • Mauro Tomassetti

26 March 2009

Two different immunosensors, recently developed for the determination of antibacterial proteins (lactoferrin and immunoglobulin G) in buffalo milk and in other commercial animal milks samples, were used in the present study. The aim was to propose th...

  • Feature Paper
  • Article
  • Open Access
1,118 Views
22 Pages

Evaluation of Holstein Cows with Tongue-Rolling: Plasma Metabolomics and Milk Proteomics

  • Chenyang Li,
  • Xiaoyang Chen,
  • Tingting Fang,
  • Jie Gao,
  • Guangyong Zhao and
  • Xianhong Gu

23 September 2025

Stereotypic behaviors are common in farm animals and often signal poor welfare. Tongue-rolling is the most prevalent stereotypic behavior in cows. In this study, we compared the plasma and milk composition of 16 high-frequency tongue-rolling cows (HT...

  • Review
  • Open Access
141 Citations
17,494 Views
22 Pages

Benefits of Lactoferrin, Osteopontin and Milk Fat Globule Membranes for Infants

  • Hans Demmelmair,
  • Christine Prell,
  • Niklas Timby and
  • Bo Lönnerdal

28 July 2017

The provision of essential and non-essential amino acids for breast-fed infants is the major function of milk proteins. In addition, breast-fed infants might benefit from bioactivities of milk proteins, which are exhibited in the intestine during the...

  • Article
  • Open Access
6 Citations
4,877 Views
16 Pages

Cow Milk Fatty Acid and Protein Composition in Different Breeds and Regions in China

  • Yunxia Zou,
  • Yifei Chen,
  • Qingyong Meng,
  • Yachun Wang and
  • Yali Zhang

30 October 2024

Cow milk is rich in proteins, fats, carbohydrates, and minerals; however, its precise nutrient content varies based on various factors. In the current study, we evaluated the differences in the fatty acid and protein contents of milk and the factors...

  • Article
  • Open Access
6 Citations
2,913 Views
14 Pages

Effects of Supplementation with an Herbal Mixture on the Antioxidant Capacity of Milk

  • Magdalena Stobiecka,
  • Jolanta Król,
  • Aneta Brodziak,
  • Renata Klebaniuk and
  • Edyta Kowalczuk-Vasilev

16 June 2023

The aim of this study was to assess the effect of the addition of a standardized herbal mixture to the feed ration for Holstein-Friesian cows on the antioxidant capacity of milk. The study was carried out on a farm specialized in breeding dairy cattl...

  • Review
  • Open Access
23 Citations
8,738 Views
18 Pages

Potential Protective Protein Components of Cow’s Milk against Certain Tumor Entities

  • Christian Leischner,
  • Sarah Egert,
  • Markus Burkard and
  • Sascha Venturelli

8 June 2021

Milk and dairy products, especially from cow’s milk, play a major role in the daily human diet. It is therefore hardly surprising that the subject of milk is being extensively researched and that many effects of individual milk components have been c...

  • Article
  • Open Access
1 Citations
3,529 Views
12 Pages

10 August 2021

Alternatives to routine antibiotic treatment of dairy cattle during the dry period before their next calving are of interest. This was a preliminary study of whether intramammary infusion of casein hydrolysate, administered alone or combined with sta...

  • Article
  • Open Access
53 Citations
12,399 Views
9 Pages

6 May 2013

Human breast milk is the best nutritional support that insures the right development and influences the immune status of the newborn infant. However, when it is not possible to breast feed, it may be necessary to use commercial infant formulas that m...

  • Article
  • Open Access
66 Citations
9,339 Views
14 Pages

Effect of Processing Intensity on Immunologically Active Bovine Milk Serum Proteins

  • Tabea Brick,
  • Markus Ege,
  • Sjef Boeren,
  • Andreas Böck,
  • Erika Von Mutius,
  • Jacques Vervoort and
  • Kasper Hettinga

31 August 2017

Consumption of raw cow’s milk instead of industrially processed milk has been reported to protect children from developing asthma, allergies, and respiratory infections. Several heat-sensitive milk serum proteins have been implied in this effect thou...

  • Article
  • Open Access
12 Citations
3,570 Views
17 Pages

Milk Allergen Micro-Array (MAMA) for Refined Detection of Cow’s-Milk-Specific IgE Sensitization

  • Victoria Garib,
  • Daria Trifonova,
  • Raphaela Freidl,
  • Birgit Linhart,
  • Thomas Schlederer,
  • Nikolaos Douladiris,
  • Alexander Pampura,
  • Daria Dolotova,
  • Tatiana Lepeshkova and
  • Rudolf Valenta
  • + 7 authors

21 May 2023

Background: Immunoglobulin-E(IgE)-mediated hypersensitivity to cow’s milk allergens is a frequent cause of severe and life-threatening anaphylactic reactions. Besides case histories and controlled food challenges, the detection of the IgE antib...

  • Review
  • Open Access
64 Citations
11,668 Views
20 Pages

Donkey milk could be considered a good and safer alternative, compared to other types of milk, for infants affected by cow’s milk protein allergy, when breastfeeding is not possible. Interestingly, donkey milk has low allergenicity, mainly due to the...

  • Article
  • Open Access
1 Citations
2,239 Views
9 Pages

25 July 2022

Mastitis is one of the most widespread diseases in dairy cows and causes huge losses for the dairy industry. Molecular markers can be used for the quick diagnosis of mastitis infection, consequently reducing the loss caused by this disease. Lactoferr...

  • Article
  • Open Access
13 Citations
4,945 Views
11 Pages

Introduction of Heated Cow’s Milk Protein in Challenge-Proven Cow’s Milk Allergic Children: The iAGE Study

  • Nicolette W. de Jong,
  • Marloes E. van Splunter,
  • Joyce A. M. Emons,
  • Kasper A. Hettinga,
  • Roy Gerth van Wijk,
  • Harry J. Wichers,
  • Huub F. J. Savelkoul,
  • Aline B. Sprikkelman,
  • R. J. Joost van Neerven and
  • Nicolette J. T. Arends
  • + 14 authors

31 January 2022

The introduction of baked milk products in cow’s milk (CM) allergic children has previously been shown to accelerate induction tolerance in a selected group of children. However, there is no standardized baked milk product on the market. Recent...

  • Article
  • Open Access
12 Citations
4,698 Views
15 Pages

21 November 2020

Lactoferrin (Lf) and other whey proteins have been isolated from red deer milk for the first time using a three-step anion and cation exchange chromatography protocol. The separated deer Lf was subject to in vitro gastric and duodenal digestions to g...

  • Review
  • Open Access
2 Citations
4,286 Views
19 Pages

Natural Bioactive Compounds in Sheep Milk: Potential Biomedical Applications

  • Zuzanna Flis,
  • Edyta Molik,
  • Anna Ptak and
  • Piotr Szatkowski

Sheep milk is a rich source of bioactive compounds with significant potential in functional foods and biomedical applications. It contains high levels of proteins, peptides, and fatty acids with numerous health-promoting properties for the human body...

  • Article
  • Open Access
3 Citations
2,740 Views
11 Pages

Genetic and Non-Genetic Variation of Milk Total Antioxidant Activity Predicted from Mid-Infrared Spectra in Holstein Cows

  • Giovanni Niero,
  • Angela Costa,
  • Marco Franzoi,
  • Giulio Visentin,
  • Martino Cassandro,
  • Massimo De Marchi and
  • Mauro Penasa

10 December 2020

Food antioxidants enhance products shelf life and stability during technological treatments through the maintenance of their physical and chemical properties. Moreover, they are endowed with several positive effects on human health, including cell me...

  • Systematic Review
  • Open Access
1 Citations
7,042 Views
20 Pages

A Systematic Review of Isotopically Measured Iron Absorption in Infants and Children Under 2 Years

  • Samantha Gallahan,
  • Stephanie Brower,
  • Hannah Wapshott-Stehli,
  • Joelle Santos and
  • Thao T. B. Ho

8 November 2024

Background: Iron is an essential element for critical biological functions, with iron deficiency negatively affecting growth and brain development and iron excess associated with adverse effects. The goal of this review is to provide a comprehensive...

  • Review
  • Open Access
179 Views
18 Pages

Functional Role and Diagnostic Potential of Biomarkers in the Early Detection of Mastitis in Dairy Cows

  • Eleonora Dall’Olio,
  • Melania Andrani,
  • Mario Baratta,
  • Fabio De Rensis and
  • Roberta Saleri

6 January 2026

Mastitis remains a prevalent and economically detrimental disease within the dairy industry, profoundly affecting animal welfare, milk quality, and overall production output. Nowadays, Somatic Cell Count (SCC) is widely recognized as the gold-standar...

  • Review
  • Open Access
73 Citations
14,807 Views
22 Pages

Milk and colostrum have high biological potential, and due to their natural origin and non-toxicity, they have many uses in cosmetics and dermatology. Research is ongoing on their potential application in other fields of medicine, but there are still...

  • Article
  • Open Access
3 Citations
2,196 Views
12 Pages

The Potential of Metalloproteinase-9 Administration to Accelerate Mammary Involution and Boost the Immune System at Dry-Off

  • Sílvia Parés,
  • Olivia Cano-Garrido,
  • Alex Bach,
  • Neus Ferrer-Miralles,
  • Antonio Villaverde,
  • Elena Garcia-Fruitós and
  • Anna Arís

30 November 2021

The dry period is decisive for the milking performance of dairy cows. The promptness of mammary gland involution at dry-off affects not only the productivity in the next lactation, but also the risk of new intra-mammary infections since it is closely...

  • Article
  • Open Access
12 Citations
4,257 Views
21 Pages

Transcriptomic Analysis of Circulating Leukocytes Obtained during the Recovery from Clinical Mastitis Caused by Escherichia coli in Holstein Dairy Cows

  • Zhangrui Cheng,
  • Sergio Palma-Vera,
  • Laura Buggiotti,
  • Mazdak Salavati,
  • Frank Becker,
  • Dirk Werling,
  • D. Claire Wathes and
  • GplusE Consortium

21 August 2022

The risk and severity of clinical infection with Escherichia coli as a causative pathogen for bovine mastitis is influenced by the hosts’ phenotypic and genotypic variables. We used RNA-Seq analysis of circulating leukocytes to investigate glob...

  • Article
  • Open Access
6 Citations
2,805 Views
12 Pages

Enzyme-Linked Aptamer Kits for Rapid, Visual, and Sensitive Determination of Lactoferrin in Dairy Products

  • Fan Zhang,
  • Hongxia Du,
  • Linsen Li,
  • Tengfei Li,
  • Jing Wang,
  • Zilei Chen,
  • Mengmeng Yan,
  • Chao Zhu and
  • Feng Qu

22 November 2022

Lactoferrin (Lf), as a popular nutritional fortification in dairy products, has the ability regulate the body’s immune system and function as a broad-spectrum antibacterial, which is of great significance to the growth and development of infant...

  • Article
  • Open Access
14 Citations
4,844 Views
12 Pages

Evaluation of Milk Colostrum Derived Lactoferrin of Sahiwal (Bos indicus) and Karan Fries (Cross-Bred) Cows for Its Anti-Cancerous Potential

  • Ankita Sharma,
  • Umesh K Shandilya,
  • Monika Sodhi,
  • Ashok K Mohanty,
  • Pranay Jain and
  • Manishi Mukesh

14 December 2019

Lactoferrin (Lf) is an iron-binding glycoprotein protein known to have immune-modulatory role and recently, its anticancerous effect against different cancer cell types was emphasized. In the present investigation, a comparative evaluation of antican...