Cognitive Application Program Interface (API) is an API of emerging artificial intelligence (AI)-based cloud services, which extracts various contextual information from non-numerical multimedia data including image and audio. Our interest is to appl...
Background/Objectives: The aim of our research was to understand how excipients, unit operations, and process parameters impact processability and resulting properties, performance, and stability of tablets containing bovine lactoferrin, a cohesive b...
Glass transition temperature (Tg) is an important material property, which predetermines the kinetic stability of amorphous solids. In the context of active pharmaceutical ingredients (API), there is motivation to maximize their Tg by forming amorpho...
Powder deaggregation in Dry Powder Inhalers (DPI) with carrier-based formulations is a key process for the effectiveness of drug administration. Carrier-wall collisions are one of the recognised mechanisms responsible for active pharmaceutical ingred...
Background: Three-dimensional printing (3DP) is rapidly advancing personalised medicine, yet systematic performance comparison with conventional manufacturing remains limited, particularly for plant-based formulations. Methods: This study compared ta...
Background/Objectives: Direct compression of cohesive powders is often challenged by poor flow, blend heterogeneity, and variable tablet quality. This study investigated how mixing time, fill level, and rotational speed affect the blending behavior a...
The generation and accumulation of an electrostatic charge from handling pharmaceutical powders is a well-known phenomenon, given the insulating nature of most APIs (Active Pharmaceutical Ingredients) and excipients. In capsule-based DPIs (Dry Powder...
Skin is our biggest organ. It interfaces our body with its environment. It is an efficient barrier to control the loss of water, the regulation of temperature, and infections by skin-resident and environmental pathogens. The barrier function of the s...
Dry powder inhalers (DPI’s) are becoming increasingly popular due to growing interest in pulmonary drug delivery and their performance is the net result of a series of processes carried out during the formulation development and manufacturing p...
It is significant to analyze the blend homogeneity of cohesive powders during pharmaceutical manufacturing in order to provide the exact content of the active pharmaceutical ingredient (API) for each individual dose unit. In this paper, an online mon...
Strain-based design (SBD) plays an important role in pipeline design and assessment of pipelines subjected to geo-hazards. Under such hazards, a pipe can be subjected to substantial plastic strains, leading to tensile failure at locations of girth we...
Magnesium stearate (MgSt), although well established as a pharmaceutical lubricant in solid oral dosage forms, plays a more complex role in carrier-based dry powder inhalers (DPIs), where it functions as a surface modifier and force control agent (FC...
Insect behavior is coordinated mainly by smell through the diverse odor-binding proteins (OBP) that allow them to identify and recognize their environment. Sensory information collected through smell is then analyzed and interpreted in the brain, all...
Sidetracking is a critical operation for bypassing damaged well sections and accessing bypassed hydrocarbons in mature reservoirs, but conventional small-diameter casing and cementing technologies face severe limitations due to narrow-clearance hydra...
This study systematically evaluates the composition-dependent wettability, apparent surface free energy, moisture sorption, and adhesion to a model mucin layer of binary polymer matrices composed of hydroxypropyl methylcellulose (HPMC), Carbopol 974P...
The olfactory system is essential for honeybees to adapt to complex and ever-changing environments and maintain cohesiveness. The Eastern honeybee Apis cerana is native to Asia and has a long history of managed beekeeping in China. In this study, we...
Tablet sticking remains a persistent manufacturing challenge in solid oral dosage forms, particularly for high-drug-load formulations, where increased API surface exposure promotes adhesion to tablet punches. Generally, glidants are used to improve p...