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20 Results Found

  • Article
  • Open Access
1 Citations
1,163 Views
24 Pages

10 January 2025

In this paper, a multi-strategy enhanced chimpanzee optimization algorithm (MSEChOA) acting on path planning for delivery vehicles is proposed to achieve the goal of shortening global path lengths for the delivery unmanned vehicles and obtaining safe...

  • Article
  • Open Access
8 Citations
4,492 Views
19 Pages

Behavioural Development of Three Former Pet Chimpanzees a Decade after Arrival at the MONA Sanctuary

  • Olga Feliu,
  • Marti Masip,
  • Carmen Maté,
  • Sònia Sánchez-López,
  • Dietmar Crailsheim and
  • Elfriede Kalcher-Sommersguter

7 January 2022

Chimpanzees used as pets and in the entertainment industry endure detrimental living conditions from early infancy onwards. The preferred option for ending their existence as pet or circus chimpanzees is their rescue and transfer to a primate sanctua...

  • Article
  • Open Access
1,764 Views
14 Pages

28 October 2024

Chimp Haven is a private, nonprofit organization that serves as the largest chimpanzee sanctuary in the world. The National Institutes of Health supports the federal sanctuary system, which is operated by Chimp Haven, to provide lifetime care for chi...

  • Review
  • Open Access
9 Citations
11,110 Views
22 Pages

12 August 2009

Studies in patients and chimpanzees that spontaneously clear Hepatitis C Virus (HCV) have demonstrated that natural immunity to the virus is induced during primary infections and that this immunity can be cross protective. These discoveries led to op...

  • Article
  • Open Access
4 Citations
5,014 Views
34 Pages

11 August 2023

Chimp Haven is a sanctuary for chimpanzees retired from biomedical research, rescued from the pet trade, or re-homed after other organizations could no longer care for them. To provide optimal care for over 300 chimpanzees, Chimp Haven’s animal...

  • Article
  • Open Access
1 Citations
3,405 Views
18 Pages

Comparing Predictors and Outcomes of Higher Allostatic Load across Zoo-Housed African Great Apes

  • Ashley N. Edes,
  • Katie L. Edwards,
  • Dawn Zimmerman,
  • Balbine Jourdan,
  • Douglas E. Crews,
  • Barbara A. Wolfe,
  • Donald L. Neiffer and
  • Janine L. Brown

Stressors over the lifespan can contribute to physiological dysregulation, or allostatic load. Allostatic load has been studied in humans using allostatic load indices (ALIs) for over 25 years, but the same methods are rarely applied to other species...

  • Article
  • Open Access
3 Citations
2,283 Views
22 Pages

8 February 2023

An improved chimpanzee optimization algorithm incorporating multiple strategies (IMSChoA) is proposed to address the problems of initialized population boundary aggregation distribution, slow convergence speed, low precision, and proneness to fall in...

  • Article
  • Open Access
1,026 Views
23 Pages

Study on Predicting Blueberry Hardness from Images for Adjusting Mechanical Gripper Force

  • Hao Yin,
  • Wenxin Li,
  • Han Wang,
  • Yuhuan Li,
  • Jiang Liu and
  • Baogang Li

Precision and non-damaging harvesting is a key direction for the development of mechanized fruit harvesting technologies. Blueberries, with their soft texture and delicate skin, present significant challenges for achieving precise and non-damaging me...

  • Article
  • Open Access
2 Citations
3,122 Views
13 Pages

Engineered Sleeping Beauty Transposon as Efficient System to Optimize Chimp Adenoviral Production

  • Samantha Baldassarri,
  • Daniela Benati,
  • Federica D’Alessio,
  • Clarissa Patrizi,
  • Eleonora Cattin,
  • Michela Gentile,
  • Angelo Raggioli and
  • Alessandra Recchia

Sleeping Beauty (SB) is the first DNA transposon employed for efficient transposition in vertebrate cells, opening new applications for genetic engineering and gene therapies. A transposon-based gene delivery system holds the favourable features of n...

  • Article
  • Open Access
19 Citations
3,463 Views
25 Pages

A Novel Chimp Optimization Algorithm with Refraction Learning and Its Engineering Applications

  • Quan Zhang,
  • Shiyu Du,
  • Yiming Zhang,
  • Hongzhuo Wu,
  • Kai Duan and
  • Yanru Lin

31 May 2022

The Chimp Optimization Algorithm (ChOA) is a heuristic algorithm proposed in recent years. It models the cooperative hunting behaviour of chimpanzee populations in nature and can be used to solve numerical as well as practical engineering optimizatio...

  • Article
  • Open Access
20 Citations
6,935 Views
25 Pages

4 July 2024

Despite the rapid advances in deep learning (DL) for object detection, existing techniques still face several challenges. In particular, object detection in adverse weather conditions (AWCs) requires complex and computationally costly models to achie...

  • Communication
  • Open Access
20 Citations
11,469 Views
10 Pages

Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

  • Nathifa Moyo,
  • Edmund G. Wee,
  • Bette Korber,
  • Kapil Bahl,
  • Samantha Falcone,
  • Sunny Himansu,
  • Adrianne L. Wong,
  • Antu K. Dey,
  • Mark Feinberg and
  • Tomáš Hanke

A vaccine will likely be one of the key tools for ending the HIV-1/AIDS epidemic by preventing HIV-1 spread within uninfected populations and achieving a cure for people living with HIV-1. The currently prevailing view of the vaccine field is to intr...

  • Article
  • Open Access
1 Citations
7,077 Views
14 Pages

Pseudo-Reference-Based Assembly of Vertebrate Transcriptomes

  • Kyoungwoo Nam,
  • Heesu Jeong and
  • Jin-Wu Nam

24 February 2016

High-throughput RNA sequencing (RNA-seq) provides a comprehensive picture of the transcriptome, including the identity, structure, quantity, and variability of expressed transcripts in cells, through the assembly of sequenced short RNA-seq reads. Alt...

  • Article
  • Open Access
595 Views
18 Pages

28 July 2025

This paper presents a hybrid indoor localization framework combining time difference of arrival (TDoA) measurements with a swarm intelligence optimization technique. To address the nonlinear optimization challenges in three-dimensional (3D) indoor lo...

  • Article
  • Open Access
8 Citations
2,924 Views
21 Pages

Optimizing Long Short-Term Memory Network for Air Pollution Prediction Using a Novel Binary Chimp Optimization Algorithm

  • Sahba Baniasadi,
  • Reza Salehi,
  • Sepehr Soltani,
  • Diego Martín,
  • Parmida Pourmand and
  • Ehsan Ghafourian

21 September 2023

Elevated levels of fine particulate matter (PM2.5) in the atmosphere present substantial risks to human health and welfare. The accurate assessment of PM2.5 concentrations plays a pivotal role in facilitating prompt responses by pertinent regulatory...

  • Article
  • Open Access
60 Citations
6,197 Views
20 Pages

Feature Extraction Using a Residual Deep Convolutional Neural Network (ResNet-152) and Optimized Feature Dimension Reduction for MRI Brain Tumor Classification

  • Suganya Athisayamani,
  • Robert Singh Antonyswamy,
  • Velliangiri Sarveshwaran,
  • Meshari Almeshari,
  • Yasser Alzamil and
  • Vinayakumar Ravi

10 February 2023

One of the top causes of mortality in people globally is a brain tumor. Today, biopsy is regarded as the cornerstone of cancer diagnosis. However, it faces difficulties, including low sensitivity, hazards during biopsy treatment, and a protracted wai...

  • Article
  • Open Access
8 Citations
3,479 Views
15 Pages

Global Repeat Map (GRM) Application: Finding All DNA Tandem Repeat Units

  • Matko Glunčić,
  • Ines Vlahović,
  • Leo Mršić and
  • Vladimir Paar

5 December 2022

Tandem repeats (TRs) are important components of eukaryotic genomes; they have both structural and functional roles: (i) they form essential chromosome structures such as centromeres and telomeres; (ii) they modify chromatin structure and affect tran...

  • Article
  • Open Access
1 Citations
2,133 Views
15 Pages

Background/Objectives: Respiratory syncytial virus (RSV) poses a substantial global health threat, particularly impacting infants and vulnerable pediatric populations through severe respiratory morbidity. Methods: We developed a novel adenoviral vect...

  • Review
  • Open Access
2,214 Views
19 Pages

11 November 2025

Human immunodeficiency virus (HIV), comprising two distinct types, HIV-1 and HIV-2, remains one of the most significant global health challenges, originating from multiple cross-species transmissions of simian immunodeficiency viruses (SIVs) in the e...

  • Article
  • Open Access
35 Citations
7,932 Views
28 Pages

Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection

  • Leo Swadling,
  • John Halliday,
  • Christabel Kelly,
  • Anthony Brown,
  • Stefania Capone,
  • M. Azim Ansari,
  • David Bonsall,
  • Rachel Richardson,
  • Felicity Hartnell and
  • Jane Collier
  • + 11 authors

An effective therapeutic vaccine for the treatment of chronic hepatitis C virus (HCV) infection, as an adjunct to newly developed directly-acting antivirals (DAA), or for the prevention of reinfection, would significantly reduce the global burden of...