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33 Results Found

  • Systematic Review
  • Open Access
4,377 Views
23 Pages

19 June 2025

Background/Objectives: Constraint-induced movement therapy (CIMT) and bimanual training (BIT) have been commonly used to improve upper limb (ULF) in paediatric populations. This study aimed to compare the efficacy of CIMT and BIT for the recovery of...

  • Article
  • Open Access
2 Citations
1,902 Views
15 Pages

Detecting Movement Changes in Children with Hemiparesis after Upper Limb Therapies: A Responsiveness Analysis of a 3D Bimanual Protocol

  • Marine Cacioppo,
  • Mathieu Lempereur,
  • Laetitia Houx,
  • Sandra Bouvier,
  • Rodolphe Bailly and
  • Sylvain Brochard

24 April 2023

The “Be an Airplane Pilot” (BE API) protocol was developed to evaluate upper limb (UL) kinematics in children with unilateral cerebral palsy (uCP) during bimanual tasks. The aim of this study was to investigate the responsiveness of this...

  • Article
  • Open Access
7 Citations
3,481 Views
16 Pages

Bimanual Movement Characteristics and Real-World Performance Following Hand–Arm Bimanual Intensive Therapy in Children with Unilateral Cerebral Palsy

  • Shailesh S. Gardas,
  • Christine Lysaght,
  • Amy Gross McMillan,
  • Shailesh Kantak,
  • John D. Willson,
  • Charity G. Patterson and
  • Swati M. Surkar

13 August 2023

The purpose of this study was to quantify characteristics of bimanual movement intensity during 30 h of hand–arm bimanual intensive therapy (HABIT) and bimanual performance (activities and participation) in real-world settings using acceleromet...

  • Article
  • Open Access
2 Citations
2,426 Views
16 Pages

30 January 2025

Background/Objectives: There is high-level research evidence supporting task-focused upper limb therapy models for children with unilateral cerebral palsy (CP). However, a knowledge gap exists in understanding how to effectively implement distributed...

  • Feature Paper
  • Article
  • Open Access
321 Views
17 Pages

7 December 2025

Background/Objectives: We studied the feasibility of incorporating a play-based bimanual ride-on-toy navigation training (RNT) program into an intensive hybrid training camp based on principles of modified constraint induced movement therapy and bima...

  • Article
  • Open Access
3 Citations
3,649 Views
14 Pages

The Effect of Bimanual Intensive Functional Training on Somatosensory Hand Function in Children with Unilateral Spastic Cerebral Palsy: An Observational Study

  • Catherine V. M. Steinbusch,
  • Anke Defesche,
  • Bertie van der Leij,
  • Eugene A. A. Rameckers,
  • Annemarie C. S. Knijnenburg,
  • Jeroen R. J. Vermeulen and
  • Yvonne J. M. Janssen-Potten

17 February 2023

(1) Background: Next to motor impairments, children with unilateral spastic cerebral palsy (CP) often experience sensory impairments. Intensive bimanual training is well known for improving motor abilities, though its effect on sensory impairments is...

  • Article
  • Open Access
2 Citations
2,714 Views
12 Pages

Bi-manual therapy (BT), mirror therapy (MT), and robot-assisted rehabilitation have been conducted in hand training in a wide range of stages in stroke patients; however, the mechanisms of action during training remain unclear. In the present study,...

  • Review
  • Open Access
9 Citations
6,517 Views
20 Pages

15 November 2024

Early detection and rehabilitation interventions are essential to optimise motor function in infants and young children with unilateral cerebral palsy. In this paper we report a clinical framework aimed at enhancing upper limb therapy for infants and...

  • Article
  • Open Access
905 Views
17 Pages

Use of Accelerometers to Monitor Motor Activity During HABIT-ILE for Chronic Stroke: An Exploratory Study

  • Merlin Somville,
  • Zélie Rosselli,
  • Edouard Ducoffre,
  • Massimo Penta,
  • Tristan Smeesters,
  • Yannick Bleyenheuft and
  • Geoffroy Saussez

31 October 2025

(1) Background: Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) is a high-dose evidence-based neurorehabilitation. This study aims to develop and validate a protocol using three inertial measurement units (IMUs) to obj...

  • Article
  • Open Access
3 Citations
4,308 Views
11 Pages

Combining Unimanual and Bimanual Therapies for Children with Hemiparesis: Is There an Optimal Delivery Schedule?

  • Ka Lai K. Au,
  • Julie L. Knitter,
  • Susan Morrow-McGinty,
  • Talita C. Campos,
  • Jason B. Carmel and
  • Kathleen M. Friel

9 June 2023

Constraint-induced movement therapy (CIMT) and bimanual therapy (BT) are among the most effective hand therapies for children with unilateral cerebral palsy (uCP). Since they train different aspects of hand use, they likely have synergistic effects....

  • Article
  • Open Access
5 Citations
4,416 Views
12 Pages

7 June 2023

Intensive therapies have become increasingly popular for children with hemiparesis in the last two decades and are specifically recommended because of high levels of scientific evidence associated with them, including multiple randomized controlled t...

  • Article
  • Open Access
4 Citations
3,015 Views
16 Pages

29 March 2024

Children with unilateral cerebral palsy (UCP) require task-oriented practice several hours per week to produce meaningful gains in affected upper extremity (UE) motor function. Clinicians find it challenging to provide services at the required intens...

  • Article
  • Open Access
4 Citations
2,435 Views
17 Pages

The pilot study assessed the utility of a training program using modified, commercially available dual-joystick-operated ride-on toys to promote unimanual and bimanual upper extremity (UE) function in children with cerebral palsy (CP). The ride-on-to...

  • Article
  • Open Access
11 Citations
1,996 Views
8 Pages

12 June 2010

During the last 30 years, the dynamic systems approach to coordination patterns contributed to shed new lights on the principles governing interlimb coordination, its dynamics, and its neural basis, predominantly in healthy people. In the present pap...

  • Article
  • Open Access
47 Citations
10,291 Views
17 Pages

Eight Weeks of Aerobic Interval Training Improves Psychomotor Function in Patients with Parkinson’s Disease—Randomized Controlled Trial

  • Jarosław Marusiak,
  • Beth E. Fisher,
  • Anna Jaskólska,
  • Krzysztof Słotwiński,
  • Sławomir Budrewicz,
  • Magdalena Koszewicz,
  • Katarzyna Kisiel-Sajewicz,
  • Bartosz Kamiński and
  • Artur Jaskólski

Background: This study examined the generalized effects of cycle ergometer aerobic interval training (AIT) on psychomotor behaviors in individuals with Parkinson’s disease (PD), including bimanual motor control, cognitive function, and neurolog...

  • Article
  • Open Access
10 Citations
4,025 Views
17 Pages

FarmDay: A Gamified Virtual Reality Neurorehabilitation Application for Upper Limb Based on Activities of Daily Living

  • Ana Rojo,
  • Jose Ángel Santos-Paz,
  • Álvaro Sánchez-Picot,
  • Rafael Raya and
  • Rodrigo García-Carmona

13 July 2022

Patients with upper limb disorders are limited in their activities of daily living and impose an important healthcare burden due to the repetitive rehabilitation they require. A way to reduce this burden is through home-based therapy using virtual re...

  • Article
  • Open Access
3,279 Views
17 Pages

26 October 2024

Background/Objectives: This quasi-experimental study examined the effectiveness of an intensive, group-based pediatric constraint-induced movement therapy (pCIMT) program for young children. Methods: Thirty-five children aged 21 months to 6 years, wi...

  • Article
  • Open Access
4 Citations
5,598 Views
14 Pages

Improved Hand Function in Children with Cerebral Palsy with Repeat Doses of Group Based Hybrid Pediatric Constraint-Induced Movement Therapy

  • Heather Roberts,
  • Angela Shierk,
  • Arianne J. Alfonso,
  • Paul Yeatts,
  • Trey L. DeJong,
  • Nancy J. Clegg,
  • Deborah Baldwin and
  • Mauricio R. Delgado

The study’s aim is to analyze the improved hand function and bimanual performance with unilateral cerebral palsy (CP) from repeat doses of an augmented, group-based pediatric constraint-induced movement therapy (pCIMT) camp. Fifteen children wi...

  • Article
  • Open Access
5 Citations
6,289 Views
14 Pages

Feasibility of a Home-Based Mirror Therapy Program in Children with Unilateral Spastic Cerebral Palsy

  • Anna Ortega-Martínez,
  • Rocío Palomo-Carrión,
  • Carlos Varela-Ferro and
  • Maria Caritat Bagur-Calafat

Children with Unilateral Spastic Cerebral Palsy (US CP) have motor and somatosensory impairments that affect one side of their body, impacting upper limb functioning. These impairments contribute negatively to children’s bimanual performance an...

  • Article
  • Open Access
11 Citations
6,056 Views
12 Pages

Deficits in executive functioning are a common feature of Alzheimer’s disease (AD) and result from impairment in the central executive system. As a result, elderly patients with early stage AD may require interventions that are more cognitively...

  • Review
  • Open Access
24 Citations
6,757 Views
13 Pages

Effects of Neurofeedback in Children with Attention-Deficit/Hyperactivity Disorder: A Systematic Review

  • Lucía Sampedro Baena,
  • Guillermo A. Cañadas-De la Fuente,
  • María Begoña Martos-Cabrera,
  • José L. Gómez-Urquiza,
  • Luis Albendín-García,
  • José Luis Romero-Bejar and
  • Nora Suleiman-Martos

25 August 2021

Attention deficit/hyperactivity disorder (ADHD) is one of the most frequent neurodevelopmental disorders in childhood and adolescence. Choosing the right treatment is critical to controlling and improving symptoms. An innovative ADHD treatment is neu...

  • Systematic Review
  • Open Access
1 Citations
1,374 Views
37 Pages

Action Observation for Children and Adolescents with Cerebral Palsy: Hope or Hype? A Systematic Review with Meta-Analysis

  • José Fierro-Marrero,
  • Carlos Donato Cabrera-López,
  • Borja Rodríguez de Rivera-Romero,
  • Alejandro López-Mejías,
  • Mirari Ochandorena-Acha,
  • Sergio Lerma-Lara and
  • Roy La Touche

20 June 2025

Cerebral palsy generates an elevated burden on both patients and health-care systems. Cost-effective therapies such as action observation therapy (AOT), have been proposed to enhance motor performance in these patients. Objective: This systematic rev...

  • Article
  • Open Access
1,887 Views
18 Pages

Feasibility of Home-Based Early Infant Hybrid Therapy in Children with Unilateral Cerebral Palsy

  • Rocío Palomo-Carrión,
  • Helena Romay-Barrero,
  • Elena Pinero-Pinto,
  • Rita-Pilar Romero-Galisteo,
  • María Coello-Villalón,
  • Asunción Ferri-Morales,
  • Purificación López-Muñoz and
  • Cristina Lirio-Romero

8 November 2024

Background: The first stage of childhood is characterized by great neuronal plasticity. In Unilateral Cerebral Palsy (UCP), it is essential to carry out early treatment, with family involvement. The aim of this study was to investigate the feasibilit...

  • Article
  • Open Access
8 Citations
6,032 Views
15 Pages

24 October 2023

The main purpose of this study is to examine the relationship between sensory-processing skills and gross motor functions, bimanual motor functions, and balance in children with cerebral palsy (CP). A total of 47 patients between the ages of 3 and 10...

  • Article
  • Open Access
7 Citations
2,897 Views
27 Pages

HRpI System Based on Wavenet Controller with Human Cooperative-in-the-Loop for Neurorehabilitation Purposes

  • Juan Daniel Ramirez-Zamora,
  • Omar Arturo Dominguez-Ramirez,
  • Luis Enrique Ramos-Velasco,
  • Gabriel Sepulveda-Cervantes,
  • Vicente Parra-Vega,
  • Alejandro Jarillo-Silva and
  • Eduardo Alejandro Escotto-Cordova

12 October 2022

There exist several methods aimed at human–robot physical interaction (HRpI) to provide physical therapy in patients. The use of haptics has become an option to display forces along a given path so as to it guides the physiotherapist protocol....

  • Article
  • Open Access
16 Citations
7,735 Views
22 Pages

Conventional and Virtual Reality Mirror Therapies in Upper Obstetric Brachial Palsy: A Randomized Pilot Study

  • Alba Yeves-Lite,
  • Juan Carlos Zuil-Escobar,
  • Carmen Martínez-Cepa,
  • Helena Romay-Barrero,
  • Asunción Ferri-Morales and
  • Rocío Palomo-Carrión

19 September 2020

The abilities of children diagnosed with Obstetric Brachial Palsy (OBP) are limited by brachial plexus injuries. Thus, their participation in the community is hindered, which involves a lower quality of life due to worse performance in activities of...

  • Article
  • Open Access
24 Citations
10,052 Views
20 Pages

Fusion of Haptic and Gesture Sensors for Rehabilitation of Bimanual Coordination and Dexterous Manipulation

  • Ningbo Yu,
  • Chang Xu,
  • Huanshuai Li,
  • Kui Wang,
  • Liancheng Wang and
  • Jingtai Liu

18 March 2016

Disabilities after neural injury, such as stroke, bring tremendous burden to patients, families and society. Besides the conventional constrained-induced training with a paretic arm, bilateral rehabilitation training involves both the ipsilateral and...

  • Article
  • Open Access
22 Citations
4,830 Views
12 Pages

19 February 2019

Variability of multi-joint essential tremor (ET) between patients and within the two upper limbs makes a visual assessment for the determination of botulinum toxin type A (BoNT-A) injections challenging. Kinematic tremor analysis guidance has succeed...

  • Article
  • Open Access
3,336 Views
19 Pages

Aim: This study explores the effects of core stabilization exercises on balance and upper extremity functions—both unilateral and bilateral—in children with cerebral palsy (CP). Method: Thirty-six children with CP (aged 5–12) were r...

  • Article
  • Open Access
2 Citations
2,435 Views
12 Pages

The Role of Specialized Instruments for Advanced Endoscopic Resections in Gastrointestinal Disease

  • Markus Brand,
  • Karl-Hermann Fuchs,
  • Joel Troya,
  • Alexander Hann and
  • Alexander Meining

7 November 2023

Introduction: Advanced endoscopic therapy techniques have been developed and have created alternative treatment options to surgical therapy for several gastrointestinal diseases. This work will focus on new endoscopic tools for special indications of...

  • Article
  • Open Access
8 Citations
6,273 Views
20 Pages

Application of Low-Intensity Modified Constraint-Induced Movement Therapy to Improve the Affected Upper Limb Functionality in Infantile Hemiplegia with Moderate Manual Ability: Case Series

  • Rocío Palomo-Carrión,
  • Rita-Pilar Romero-Galisteo,
  • Elena Pinero-Pinto,
  • Purificación López-Muñoz,
  • Helena Romay-Barrero and
  • Francisco García-Muro San José

4 September 2020

Objective: To assess the functionality of the affected upper limb in children diagnosed with hemiplegia aged between 4 and 8 years after applying low-intensity modified Constraint-Induced Movement Therapy (mCIMT). Methods: Prospective case series stu...

  • Systematic Review
  • Open Access
2 Citations
4,431 Views
10 Pages

Systematic Review and Meta-Analysis of Intervention Techniques in Occupational Therapy for Babies and Children with Obstetric Brachial Plexus Palsy

  • María Martínez-Carlón-Reina,
  • Janine Hareau-Bonomi,
  • Mª Pilar Rodríguez-Pérez and
  • Elisabet Huertas-Hoyas

17 October 2024

(1) Background: Obstetric brachial plexus palsy (OBPP) is an unpredictable and unpreventable neurological injury, caused by shoulder dystocia during birth, that affects the brachial plexus and leads to motor and sensory deficits in the child’s...

  • Study Protocol
  • Open Access
1,549 Views
18 Pages

ACT-ON-DIP: Study Protocol of a Randomized Controlled Trial of a Home-Based ACTion Observation Tele-RehabilitatioN for Upper Limb in Children with DIPlegic Cerebral Palsy

  • Elena Beani,
  • Elisa Matteucci,
  • Elisa Sicola,
  • Giada Martini,
  • Maria Chiara Di Lieto,
  • Clara Bombonato,
  • Valentina Menici,
  • Annalisa Cotardo,
  • Marta Rizzo and
  • Giuseppina Sgandurra
  • + 17 authors

14 September 2025

Background: Children with diplegic Cerebral Palsy often exhibit upper-limb (UL) motor impairments compounded by deficits in visuospatial, sensory, and executive functions. Despite this, research has primarily focused on lower-limb rehabilitation, lea...