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20 Results Found

  • Proceeding Paper
  • Open Access
2 Citations
2,713 Views
8 Pages

Xanthine Oxidase Inhibition by Aqueous Extract of Limonium brasiliense (Plumbaginaceae)

  • Silvana Andrea Rodriguez,
  • Ana Paula Murray and
  • José Manuel Leiro

14 December 2020

Limonium brasiliense (Boiss.) Kuntze (Plumbaginaceae) is a medicinal plant that is popularly used in the folk medicine. In this study, we examined xanthine oxidase (XO) inhibitory activity of the aqueous fraction of Limonium brasiliense extract and i...

  • Article
  • Open Access
759 Views
17 Pages

An IUCN-Based Conservation Perspective of the Genus Limonium (Plumbaginaceae) in Greece: From Assessing Species to Identifying Patterns of Extinction Risk and Conservation Needs

  • Efstathios Apostolopoulos,
  • Anna-Thalassini Valli,
  • Nikolaos Gkournelos,
  • Apostolos-Emmanouil Bazanis,
  • Katerina Koutsovoulou and
  • Theophanis Constantinidis

17 October 2025

This study presents the first comprehensive IUCN-based assessment for all 88 Limonium species occurring in Greece, aiming to close a critical conservation gap for this highly diverse and important genus in the country. To identify patterns of extinct...

  • Article
  • Open Access
743 Views
14 Pages

Characterization of the Phytochemical Profile of Halophytes (Limonium Mill., Plumbaginaceae) with Natural Deep Eutectic Solvents Extraction

  • Antonio Ruiz-Medina,
  • David J. Parras-Guijarro,
  • Carlos Salazar-Mendías and
  • Eulogio J. Llorent-Martínez

22 August 2025

Limonium Mill. (Plumbaginaceae) is a genus comprising many species, some of which are reported to possess high bioactivity and are used as food, medicinal herbs, and fodder. Here we report the use of different deep eutectic solvents (DESs) and natura...

  • Article
  • Open Access
6 Citations
4,104 Views
15 Pages

17 January 2021

Ex situ plant collections established from seeds of natural populations are key tools for understanding mating systems of intricate taxonomic complexes, as in the Limonium Mill. genus (sea lavenders, Plumbaginaceae). Plants show a polymorphic sexual...

  • Article
  • Open Access
6 Citations
5,454 Views
22 Pages

Integrative Taxonomy of Armeria Taxa (Plumbaginaceae) Endemic to Sardinia and Corsica

  • Manuel Tiburtini,
  • Gianluigi Bacchetta,
  • Marco Sarigu,
  • Salvatore Cambria,
  • Paolo Caputo,
  • Daniele De Luca,
  • Gianniantonio Domina,
  • Alessia Turini and
  • Lorenzo Peruzzi

5 June 2023

Sardinia and Corsica are two Mediterranean islands where the genus Armeria is represented by 11 taxa, 10 out of which are endemic. An integrative approach, using molecular phylogeny, karyology, and seed and plant morphometry was used to resolve the c...

  • Article
  • Open Access
13 Citations
4,923 Views
21 Pages

Integrative Taxonomy of Armeria arenaria (Plumbaginaceae), with a Special Focus on the Putative Subspecies Endemic to the Apennines

  • Manuel Tiburtini,
  • Giovanni Astuti,
  • Fabrizio Bartolucci,
  • Gabriele Casazza,
  • Lucia Varaldo,
  • Daniele De Luca,
  • Maria Vittoria Bottigliero,
  • Gianluigi Bacchetta,
  • Marco Porceddu and
  • Lorenzo Peruzzi
  • + 2 authors

14 July 2022

Three subspecies of Armeria arenaria are reported from Italy, two of which are considered endemic to the Apennines. The taxonomic value of these two taxa (A. arenaria subsp. marginata and A. arenaria subsp. apennina) is unclear. Moreover, the relatio...

  • Article
  • Open Access
5 Citations
3,298 Views
21 Pages

Constitutive and Adaptive Traits of Environmental Stress Tolerance in the Threatened Halophyte Limonium angustebracteatum Erben (Plumbaginaceae)

  • Ricardo Mir,
  • Ignacio Romero,
  • Sara González-Orenga,
  • P. Pablo Ferrer-Gallego,
  • Emilio Laguna,
  • Monica Boscaiu,
  • Lăcrămioara Oprică,
  • Marius-Nicușor Grigore and
  • Oscar Vicente

22 April 2022

Limonium angustebracteatum is a halophyte endemic to the E and SE Iberian Peninsula with interest in conservation. Salt glands represent an important adaptive trait in recretohalophytes like this and other Limonium species, as they allow the excretio...

  • Article
  • Open Access
4 Citations
3,217 Views
32 Pages

Ovule Transcriptome Analysis Discloses Deregulation of Genes and Pathways in Sexual and Apomictic Limonium Species (Plumbaginaceae)

  • Ana D. Caperta,
  • Isabel Fernandes,
  • Sofia I. R. Conceição,
  • Isabel Marques,
  • Ana S. Róis and
  • Octávio S. Paulo

12 April 2023

The genus Limonium Mill. (sea lavenders) includes species with sexual and apomixis reproductive strategies, although the genes involved in these processes are unknown. To explore the mechanisms beyond these reproduction modes, transcriptome profiling...

  • Article
  • Open Access
4 Citations
2,874 Views
20 Pages

Unravelling the Combined Use of Soil and Microbial Technologies to Optimize Cultivation of Halophyte Limonium algarvense (Plumbaginaceae) Using Saline Soils and Water

  • Amaia Nogales,
  • Salvadora Navarro-Torre,
  • Maria Manuela Abreu,
  • Erika S. Santos,
  • Ana Cortinhas,
  • Rosalba Fors,
  • Marion Bailly,
  • Ana Sofia Róis and
  • Ana Delaunay Caperta

Salt-affected soils have detrimental effects on agriculture and ecosystems. However, these soils can still be used for halophyte (salt-tolerant plants) cultivation using brackish and/or saline water. In this study, we employed soil technologies and m...

  • Feature Paper
  • Article
  • Open Access
8 Citations
2,780 Views
19 Pages

18 November 2022

The delimitation of Limonium taxa is highly complicated due to hybridization, polyploidy, and apomixis. Many “microspecies” were described and aggregated into groups, most of which are still poorly known from both molecular and morphologi...

  • Article
  • Open Access
26 Citations
6,324 Views
18 Pages

Identification of Phenolic Compounds by LC-MS/MS and Evaluation of Bioactive Properties of Two Edible Halophytes: Limonium effusum and L. sinuatum

  • Ipek Baysal,
  • Melike Ekizoglu,
  • Abdulselam Ertas,
  • Burak Temiz,
  • Hale Gamze Agalar,
  • Samiye Yabanoglu-Ciftci,
  • Hamdi Temel,
  • Gulberk Ucar and
  • Fatma Pinar Turkmenoglu

This work aimed to evaluate the phenolic content and in vitro antioxidant, antimicrobial and enzyme inhibitory activities of the methanol extracts and their fractions of two edible halophytic Limonium species, L. effusum (LE) and L. sinuatum (LS). Th...

  • Article
  • Open Access
16 Citations
4,137 Views
11 Pages

Morphological Characterization of Tetraploids of Limonium sinuatum (L.) Mill. Produced by Oryzalin Treatment of Seeds

  • Shiro Mori,
  • Masaki Yahata,
  • Ayano Kuwahara,
  • Yurina Shirono,
  • Yasufumi Ueno,
  • Misaki Hatanaka,
  • Yoshimi Honda,
  • Keita Sugiyama,
  • Naho Murata and
  • Takahiro Wagatsuma
  • + 1 author

Limonium sinuatum (L.) Mill. (2n = 2x = 16) is a popular ornamental plant with dimorphism of pollen grains (type A and type B) and stigmas (papilla and cob-like). We applied polyploidy breeding to this species in order to introduce desirable traits....

  • Systematic Review
  • Open Access
11 Citations
3,443 Views
21 Pages

Chemical Constituents, Anticancer and Anti-Proliferative Potential of Limonium Species: A Systematic Review

  • Naiara Cássia Gancedo,
  • Raquel Isolani,
  • Natalia Castelhano de Oliveira,
  • Celso Vataru Nakamura,
  • Daniela Cristina de Medeiros Araújo,
  • Andreia Cristina Conegero Sanches,
  • Fernanda Stumpf Tonin,
  • Fernando Fernandez-Llimos,
  • Danielly Chierrito and
  • João Carlos Palazzo de Mello

14 February 2023

Limonium species represent a source of bioactive compounds that have been widely used in folk medicine. This study aimed to synthesize the anticancer and anti-proliferative potential of Limonium species through a systematic review. Searches were perf...

  • Review
  • Open Access
50 Citations
7,281 Views
14 Pages

Plumbagin, a Natural Compound with Several Biological Effects and Anti-Inflammatory Properties

  • Giovannamaria Petrocelli,
  • Pasquale Marrazzo,
  • Laura Bonsi,
  • Federica Facchin,
  • Francesco Alviano and
  • Silvia Canaider

31 May 2023

Phytochemicals from various medicinal plants are well known for their antioxidant properties and anti-cancer effects. Many of these bioactive compounds or natural products have demonstrated effects against inflammation, while some showed a role that...

  • Feature Paper
  • Article
  • Open Access
60 Citations
7,528 Views
18 Pages

The Endemic Vascular Flora of Sardinia: A Dynamic Checklist with an Overview of Biogeography and Conservation Status

  • Mauro Fois,
  • Emmanuele Farris,
  • Giacomo Calvia,
  • Giuliano Campus,
  • Giuseppe Fenu,
  • Marco Porceddu and
  • Gianluigi Bacchetta

23 February 2022

The vascular flora of Sardinia has been investigated for more than 250 years, with particular attention to the endemic component due to their phylogeographic and conservation interest. However, continuous changes in the floristic composition through...

  • Article
  • Open Access
9 Citations
3,031 Views
13 Pages

27 August 2023

Limonium bicolor is a perennial herbaceous plant belonging to the Plumbaginaceae family. It can be used as a dried flower or in cut flower arrangements and serves as a model recretohalophyte. Its genome sequencing has been recently completed. However...

  • Article
  • Open Access
10 Citations
2,885 Views
14 Pages

Synergistic Anticancer Activity of Plumbagin and Xanthohumol Combination on Pancreatic Cancer Models

  • Ranjith Palanisamy,
  • Nimnaka Indrajith Kahingalage,
  • David Archibald,
  • Ilaria Casari and
  • Marco Falasca

16 February 2024

Among diverse cancers, pancreatic cancer is one of the most aggressive types due to inadequate diagnostic options and treatments available. Therefore, there is a necessity to use combination chemotherapy options to overcome the chemoresistance of pan...

  • Article
  • Open Access
5 Citations
2,555 Views
11 Pages

Two Allelopathic Substances from Plumbago rosea Stem Extracts and Their Allelopathic Effects

  • Thang Lam Lun,
  • Arihiro Iwasaki,
  • Kiyotake Suenaga and
  • Hisashi Kato-Noguchi

26 August 2022

The plant Plumbago rosea Linn., belonging to the Plumbaginaceae family, is an important medicinal herb distributed in part of Southeast Asia, and there are many reports of its pharmacological properties. However, the allelopathic activities of P. ros...

  • Article
  • Open Access
8 Citations
2,375 Views
16 Pages

Antiparasitic Activity of Plumbago auriculata Extracts and Its Naphthoquinone Plumbagin against Trypanosoma cruzi

  • Raiza Brandão Peres,
  • Marcos Meuser Batista,
  • Ana Luíza Rangel Bérenger,
  • Flávia da Cunha Camillo,
  • Maria Raquel Figueiredo and
  • Maria de Nazaré Correia Soeiro

Chagas disease (CD) caused by the protozoan Trypanosoma cruzi affects more than six million people worldwide. Treatment is restricted to benznidazole (Bz) and nifurtimox (Nf) that display low activity in the later chronic stage besides triggering tox...

  • Review
  • Open Access
3 Citations
2,661 Views
40 Pages

The Occurrence, Uses, Biosynthetic Pathway, and Biotechnological Production of Plumbagin, a Potent Antitumor Naphthoquinone

  • Polavarapu B. Kavi Kishor,
  • Bangaru Naidu Thaddi,
  • Rajasheker Guddimalli,
  • Tukaram Dayaram Nikam,
  • Krothapalli Raja Surya Sambasiva Rao,
  • Rupasree Mukhopadhyay and
  • Prashant Singam

Plumbagin is an important naphthoquinone with potent anticancer properties besides multitudinous uses in healthcare. It is produced in a limited number of species and families but mostly in the roots of Plumbaginaceae family members. The biosynthetic...