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24 Results Found

  • Review
  • Open Access
14 Citations
3,278 Views
15 Pages

Achromobacter spp. Surgical Site Infections: A Systematic Review of Case Reports and Case Series

  • Eve Ronin,
  • Christian Derancourt,
  • André Cabié and
  • Karine Marion-Sanchez

Achromobacter species are isolated from rare but severe healthcare-associated infections, including surgical site infections. They are considered to preferentially infect immunocompromised patients but so far with limited evidence. We conducted a sys...

  • Article
  • Open Access
14 Citations
3,586 Views
12 Pages

Adaptive Interactions of Achromobacter spp. with Pseudomonas aeruginosa in Cystic Fibrosis Chronic Lung Co-Infection

  • Angela Sandri,
  • Janus Anders Juul Haagensen,
  • Laura Veschetti,
  • Helle Krogh Johansen,
  • Søren Molin,
  • Giovanni Malerba,
  • Caterina Signoretto,
  • Marzia Boaretti and
  • Maria M. Lleo

In the lungs of patients with cystic fibrosis (CF), the main pathogen Pseudomonas aeruginosa is often co-isolated with other microbes, likely engaging in inter-species interactions. In the case of chronic co-infections, this cohabitation can last for...

  • Article
  • Open Access
11 Citations
3,322 Views
11 Pages

Achromobacter spp. in a Cohort of Non-Selected Pre- and Post-Lung Transplant Recipients

  • Cornelia Geisler Crone,
  • Omid Rezahosseini,
  • Hans Henrik Lawaetz Schultz,
  • Tavs Qvist,
  • Helle Krogh Johansen,
  • Susanne Dam Nielsen and
  • Michael Perch

28 January 2022

Achromobacter is an opportunistic pathogen that mainly causes chronic lung infections in cystic fibrosis (CF) patients and is associated with increased mortality. Little is known about Achromobacter spp. in the lung transplant recipient (LTXr) popula...

  • Article
  • Open Access
9 Citations
3,320 Views
13 Pages

Achromobacter spp. Adaptation in Cystic Fibrosis Infection and Candidate Biomarkers of Antimicrobial Resistance

  • Angela Sandri,
  • Laura Veschetti,
  • Giulia Maria Saitta,
  • Rebeca Passarelli Mantovani,
  • Maria Carelli,
  • Gloria Burlacchini,
  • Sara Preato,
  • Claudio Sorio,
  • Paola Melotti and
  • Giovanni Malerba
  • + 6 authors

17 August 2022

Achromobacter spp. can establish occasional or chronic lung infections in patients with cystic fibrosis (CF). Chronic colonization has been associated with worse prognosis highlighting the need to identify markers of bacterial persistence. To this pu...

  • Article
  • Open Access
8 Citations
3,915 Views
10 Pages

Mobilome Analysis of Achromobacter spp. Isolates from Chronic and Occasional Lung Infection in Cystic Fibrosis Patients

  • Laura Veschetti,
  • Angela Sandri,
  • Cristina Patuzzo,
  • Paola Melotti,
  • Giovanni Malerba and
  • Maria M. Lleò

Achromobacter spp. is an opportunistic pathogen that can cause lung infections in patients with cystic fibrosis (CF). Although a variety of mobile genetic elements (MGEs) carrying antimicrobial resistance genes have been identified in clinical isolat...

  • Article
  • Open Access
4 Citations
2,357 Views
12 Pages

In Vivo Inflammation Caused by Achromobacter spp. Cystic Fibrosis Clinical Isolates Exhibiting Different Pathogenic Characteristics

  • Angela Sandri,
  • Giulia Maria Saitta,
  • Laura Veschetti,
  • Federico Boschi,
  • Rebeca Passarelli Mantovani,
  • Maria Carelli,
  • Paola Melotti,
  • Caterina Signoretto,
  • Marzia Boaretti and
  • Maria M. Lleò
  • + 1 author

Achromobacter spp. lung infection in cystic fibrosis has been associated with inflammation, increased frequency of exacerbations, and decline of respiratory function. We aimed to evaluate in vivo the inflammatory effects of clinical isolates exhibiti...

  • Article
  • Open Access
3 Citations
2,929 Views
12 Pages

Genetic and Biochemical Characterization of AXC-2 from Achromobacter ruhlandii

  • Mariana Papalia,
  • Francisco González-Espinosa,
  • Fátima Quiroga Castedo,
  • Gabriel Gutkind,
  • María Soledad Ramírez,
  • Pablo Power and
  • Marcela Radice

27 January 2024

Achromobacter spp. are intrinsically resistant to multiple antibiotics and can also acquire resistance to those commonly used for the treatment of respiratory infections, especially in patients with cystic fibrosis. The aim of this study was to perfo...

  • Article
  • Open Access
12 Citations
3,392 Views
14 Pages

25 February 2022

Achromobacter spp. are intrinsically multidrug-resistant environmental microorganisms which are known to cause opportunistic, nosocomial, and sometimes chronic infections. The existing literature yields scarcely any larger datasets, especially with r...

  • Article
  • Open Access
7 Citations
3,744 Views
17 Pages

Decabrominated diphenyl ether (BDE-209) is a primary component of the brominated flame retardants used in a variety of industrial and domestic applications. BDE-209 bioaccumulates in aquatic organisms and has been identified as an emerging contaminan...

  • Brief Report
  • Open Access
1,241 Views
12 Pages

Development of a Simple and Accurate Molecular Protocol Using 16SrRNA for Species-Specific Identification of Achromobacter spp.

  • Giulia Maria Saitta,
  • Laura Veschetti,
  • Rebecca Feletti,
  • Angela Sandri,
  • Marzia Boaretti,
  • Paola Melotti,
  • Maria Carelli,
  • Maria M. Lleò,
  • Giovanni Malerba and
  • Caterina Signoretto

The Achromobacter genus comprises 22 species and various genogroups. Some species with higher virulence or antibiotic resistance are more likely to cause chronic infections in people with cystic fibrosis (CF). Current identification methods often fai...

  • Article
  • Open Access
9 Citations
4,363 Views
23 Pages

Compounding Achromobacter Phages for Therapeutic Applications

  • Ana Georgina Cobián Güemes,
  • Tram Le,
  • Maria Isabel Rojas,
  • Nicole E. Jacobson,
  • Helena Villela,
  • Katelyn McNair,
  • Shr-Hau Hung,
  • Lili Han,
  • Lance Boling and
  • Anca M. Segall
  • + 11 authors

30 July 2023

Achromobacter species colonization of Cystic Fibrosis respiratory airways is an increasing concern. Two adult patients with Cystic Fibrosis colonized by Achromobacter xylosoxidans CF418 or Achromobacter ruhlandii CF116 experienced fatal exacerbations...

  • Article
  • Open Access
2,979 Views
14 Pages

29 January 2024

Bakanae is one of the important diseases of rice in Bangladesh that causes substantial yield loss every year. We collected thirty isolates of Fusarium spp. from bakanae-infected rice plants from different agroecological zones of Bangladesh and invest...

  • Article
  • Open Access
7 Citations
3,735 Views
19 Pages

Analysis of a Novel Bacteriophage vB_AchrS_AchV4 Highlights the Diversity of Achromobacter Viruses

  • Laura Kaliniene,
  • Algirdas Noreika,
  • Algirdas Kaupinis,
  • Mindaugas Valius,
  • Edvinas Jurgelaitis,
  • Justas Lazutka,
  • Rita Meškienė and
  • Rolandas Meškys

27 February 2021

Achromobacter spp. are ubiquitous in nature and are increasingly being recognized as emerging nosocomial pathogens. Nevertheless, to date, only 30 complete genome sequences of Achromobacter phages are available in GenBank, and nearly all of those pha...

  • Review
  • Open Access
4 Citations
2,992 Views
16 Pages

Rarely Encountered Gram-Negative Rods and Lung Transplant Recipients: A Narrative Review

  • Eric Farfour,
  • Antoine Roux,
  • Edouard Sage,
  • Hélène Revillet,
  • Marc Vasse and
  • Alexandre Vallée

The respiratory tract of lung transplant recipients (LTR) is likely to be colonized with non-fermentative Gram-negative rods. As a consequence of the improvements in molecular sequencing and taxonomy, an increasing number of bacterial species have be...

  • Article
  • Open Access
7 Citations
3,475 Views
14 Pages

Characterization of Novel Lytic Bacteriophages of Achromobacter marplantensis Isolated from a Pneumonia Patient

  • Hiu Tat Chan,
  • Heng Ku,
  • Ying Ping Low,
  • Steven Batinovic,
  • Mwila Kabwe,
  • Steve Petrovski and
  • Joseph Tucci

8 October 2020

Achromobacter spp. are becoming increasingly associated with lung infections in patients suffering from cystic fibrosis (CF). A. marplatensis, which is closely related to A. xylosoxidans, has been isolated from the lungs of CF patients and other huma...

  • Review
  • Open Access
8 Citations
9,073 Views
31 Pages

Rare or Unusual Non-Fermenting Gram-Negative Bacteria: Therapeutic Approach and Antibiotic Treatment Options

  • Nicholas Geremia,
  • Andrea Marino,
  • Andrea De Vito,
  • Federico Giovagnorio,
  • Stefano Stracquadanio,
  • Agnese Colpani,
  • Stefano Di Bella,
  • Giordano Madeddu,
  • Saverio Giuseppe Parisi and
  • Giuseppe Nunnari
  • + 1 author

Non-fermenting Gram-negative bacteria (NFGNB) are a heterogeneous group of opportunistic pathogens increasingly associated with healthcare-associated infections. While Pseudomonas aeruginosa, Acinetobacter baumannii, and Stenotrophomonas maltophilia...

  • Review
  • Open Access
15 Citations
25,197 Views
40 Pages

Bacterial Contamination of Antiseptics, Disinfectants and Hand Hygiene Products in Healthcare Facilities in High-Income Countries: A Scoping Review

  • Palpouguini Lompo,
  • Anne-Sophie Heroes,
  • Esenam Agbobli,
  • Vera Kühne,
  • Halidou Tinto,
  • Dissou Affolabi and
  • Jan Jacobs

19 April 2023

This scoping review addresses bacterial contamination of antiseptics, low-level disinfectants, and hand hygiene products in healthcare settings in high-income countries. Over 70 years, 114 articles were found: 68 outbreaks, 13 pseudo-outbreaks and 33...

  • Article
  • Open Access
10 Citations
3,459 Views
19 Pages

Cervicovaginal-Microbiome Analysis by 16S Sequencing and Real-Time PCR in Patients from Novosibirsk (Russia) with Cervical Lesions and Several Years after Cancer Treatment

  • Mikhail K. Ivanov,
  • Evgeny V. Brenner,
  • Anastasia A. Hodkevich,
  • Victoria V. Dzyubenko,
  • Sergey E. Krasilnikov,
  • Alphiya S. Mansurova,
  • Irina E. Vakhturova,
  • Eduard F. Agletdinov,
  • Anastasia O. Shumeikina and
  • Sergei E. Titov
  • + 1 author

Disturbed cervicovaginal-microbiome (CVM) structure promotes human papillomavirus (HPV) persistence and reflects risks of cervical lesions and cancer onset and recurrence. Therefore, microbiomic biomarkers may be useful for cervical disease screening...

  • Article
  • Open Access
15 Citations
7,971 Views
12 Pages

Larvicidal Activities against Aedes aegypti of Supernatant and Pellet Fractions from Cultured Bacillus spp. Isolated from Amazonian Microenvironments

  • Ricardo M. Katak,
  • Elerson M. Rocha,
  • Juan C. Oliveira,
  • Veranilce A. Muniz,
  • Marta R. Oliveira,
  • Francisco A. S. Ferreira,
  • William R. Silva,
  • Rosemary A. Roque,
  • Antonia Q. L. de Souza and
  • Wanderli P. Tadei
  • + 3 authors

The Aedes aegypti mosquito is the primary vector of Dengue, Chikungunya and Zika causing major problems for public health, which requires new strategies for its control, like the use of entomopathogenic microorganisms. In this study, bacteria from va...

  • Article
  • Open Access
15 Citations
4,908 Views
13 Pages

Contamination of Hospital Surfaces with Bacterial Pathogens under the Current COVID-19 Outbreak

  • Andrei A. Pochtovyi,
  • Daria V. Vasina,
  • Daria D. Kustova,
  • Elizaveta V. Divisenko,
  • Nadezhda A. Kuznetsova,
  • Olga A. Burgasova,
  • Ludmila V. Kolobukhina,
  • Artem P. Tkachuk,
  • Vladimir A. Gushchin and
  • Alexander L. Gintsburg

The SARS-CoV-2 pandemic remains a global health issue for several reasons, such as the low vaccination rates and a lack of developed herd immunity to the evolution of SARS-CoV-2, as well as its potential inclination to elude neutralizing antibodies....

  • Brief Report
  • Open Access
7 Citations
3,084 Views
13 Pages

Cefiderocol for the Treatment of Infections by VIM-Type-Producing Gram-Negative Bacteria

  • Cristina Kirkegaard-Biosca,
  • Ester del Barrio-Tofiño,
  • Miguel Villamarín,
  • Nieves Larrosa,
  • David Campany,
  • Juan José González-López,
  • Ricard Ferrer,
  • Belén Viñado,
  • Laura Doménech and
  • Ibai Los-Arcos
  • + 3 authors

12 September 2024

VIM-type-producing Gram-negative bacteria (GNB) infections are difficult to treat. This is a retrospective single-center study of 34 patients who received cefiderocol for the treatment of VIM-type-producing GNB infections, including 25 Pseudomonas sp...

  • Article
  • Open Access
7 Citations
5,200 Views
17 Pages

Impact of Lactobacillus acidophilus—La5 on Composition and Metabolism of the Intestinal Microbiota of Type 2 Diabetics (T2D) and Healthy Individuals Using a Microbiome Model

  • Mateus Kawata Salgaço,
  • Fellipe Lopes de Oliveira,
  • Adilson Sartoratto,
  • Victoria Mesa,
  • Marcia Pinto Alves Mayer and
  • Katia Sivieri

Type 2 diabetes is characterized by dysbiosis in the gut, which may lead to systemic inflammation. Therefore, the use of probiotics may help to achieve a balanced microbiota and improve glycemic control. The aim of this study was to verify the impact...

  • Article
  • Open Access
847 Views
15 Pages

Molecular Epidemiological Surveillance of Carbapenem-Resistant Gram-Negative Bacteria in Southern Lebanon

  • Anwar Al Souheil,
  • Hadi Hussein,
  • Ziad Jabbour,
  • Sara Barada,
  • Jose-Rita Gerges,
  • Ghada Derbaj,
  • Abdallah Kurdi,
  • Hassan Jamil Kazma,
  • Nour Nahouli and
  • Antoine Abou Fayad
  • + 6 authors

7 November 2025

Introduction: Carbapenem-resistant Gram-negative bacteria (CR-GNB) are rapidly spreading pathogens that increase morbidity and mortality in hospital settings and significantly restrict available treatment options worldwide. The lack of molecular epid...

  • Article
  • Open Access
29 Citations
4,385 Views
18 Pages

In vitro Activity of Cefiderocol and Comparators against Carbapenem-Resistant Gram-Negative Pathogens from France and Belgium

  • Saoussen Oueslati,
  • Pierre Bogaerts,
  • Laurent Dortet,
  • Sandrine Bernabeu,
  • Hend Ben Lakhal,
  • Christopher Longshaw,
  • Youri Glupczynski and
  • Thierry Naas

4 October 2022

Infections with carbapenem-resistant (CR) Gram-negative (GN) pathogens have increased in many countries worldwide, leaving only few therapeutic options. Cefiderocol (CFDC) is approved in Europe for the treatment of aerobic GN infections in adults wit...