This study investigates landslide occurrence in Taiwan, a region highly susceptible to landslides due to steep mountains and frequent typhoons (TYPs). The primary objective is to understand how both geomorphological factors and TYP characteristics co...
Sirtuin-3 (Sirt3) is a major mitochondrial deacetylase enzyme that regulates multiple metabolic pathways, and its expression is decreased in diabetes type 1 and type 2 diabetes. This study aimed to elucidate Sirt3′s molecular mechanism in regul...
Atrazine (ATR) is a herbicide globally used to eliminate undesired weeds. Herbicide usage leads to various adverse effects on human health and the environment. The primary source of herbicides in humans is the food laced with the herbicides. The ATR...
Adipocytes not only act as the body’s energy warehouse – they also effectively form a highly active endocrine organ [...]
Nichtsteroidale Antirheumatika und Antiphlogistika vom Typ der Arylessig- und Arylpropionsäuren. [...]
To continuously improve air quality, after implementation of the “Clean Air Action Plan, 2013–2017” (CAAP), the “Three-year Action Plan to Fight Air Pollution” (TYP) was further conducted from 2018 to 2020. However, the effectiveness of the TYP remai...
This study was conducted to evaluate the influence of kernel size and its potential interaction with genotype on durum wheat quality with emphases on kernel physical characteristics, milling performance, and color-related quality parameters. Wheat sa...
Terpenoids, also known as isoprenoids, are a broad and diverse class of plant natural products with significant industrial and pharmaceutical importance. Many of these natural products have antitumor, anti-inflammatory, antibacterial, antiviral, and...
Background/Objectives: Metabolic reprogramming is an essential feature of tumors. Mitochondrial sirtuins SIRT3 and SIRT5 differently regulate glutamine metabolism with SIRT5 inhibiting glutaminase (GLS) and SIRT3 increasing glutamate dehydrogenase (G...
In vitro expansion-mediated replicative senescence has severely limited the clinical applications of mesenchymal stem cells (MSCs). Accumulating studies manifested that nicotinamide adenine dinucleotide (NAD+) depletion is closely related to stem cel...
Vascular calcification (VC) is a common pathophysiological process of chronic kidney disease (CKD). Sirtuin 3 (Sirt3), a major NAD+-dependent protein deacetylase predominantly in mitochondria, is involved in the pathogenesis of VC. We previously repo...
Previous studies have demonstrated that melatonin (MLT) enhances boar sperm motility by modulating energy metabolism status, yet the underlying mechanisms remain incompletely understood. This study aims to investigate whether sirtuin 3 (SIRT3), a key...
Wstęp: Indywidualne ryzyko zachorowania na raka płuca zależy nie tylko od ekspozycji na dym tytoniowy, ale również od aktywności enzymów biorących udział w aktywacji lub deaktywacji substancji rakotwórczych. Arylamino N-acetylotransferazy (EC 2.3.1.5...
The purpose of the paper is to study new algebraic operations and fundamental properties of totally dependent-neutrosophic sets and totally dependent-neutrosophic soft sets. First, the in-coordination relationships among the original inclusion relati...
Pruning experimental studies have been performed in different vineyards, in France, USA and Australia. This article investigates and models the effects of pruning quality on the installation of desiccation cones and wood necrotization. Two different...
In the process of continuous improvement of manufacturing processes, this study was developed within the framework of the Ecovoss project, based on the inclusion of lightweight and new materials parts in the automotive sector. The objective was based...
When agents need to collaborate without previous coordination, the multi-agent cooperation problem transforms into an ad hoc teamwork (AHT) problem. Mainstream research on AHT is divided into type-based and type-free methods. The former depends on kn...
The study investigated the effect of pterostilbene (PTE) on intestinal glucose absorption and its underlying mechanisms in high-intensity swimming exercise (HISE)-treated mice. Male C57BL/6 mice were treated with PTE for 4 weeks and performed high-in...
Immunoterapia z zastosowaniem leków blokujących punkty kontrolne zdaje się rewolucjonizować leczenie nowotworów litych, w tym raka płuca. Blokery szlaku PD-1, PD-L1 wykazały skuteczność w zakresie długotrwałego przeżycia w zaawansowanym raku płuca z...
This study systematically investigates the effects of enzyme type (Alcalase, Trypsin, Protamex) on the properties of rice peptide nanoparticles (RPNs) and their efficacy in stabilizing high internal phase emulsions (HIPEs). RPNs prepared with Alcalas...
Sperm quality is an important indicator to evaluate the reproduction ability of animals. Nicotinamide mononucleotide (NMN) participates in cell energy metabolism and reduces cell oxidative stress. However, the effect and regulatory mechanism of NMN o...
Polymer-based capacitive strain gauges are a novel and promising concept for measuring large displacements and strains in various applications. These novel sensors allow for high strain, well above the maximum values achieved with state-of-the-art st...
Oxidative stress has been identified as a major cause of cellular injury in a variety of neurodegenerative disorders. This study aimed to investigate the cytoprotective effects of piceatannol on hydrogen peroxide (H2O2)-induced pheochromocytoma-12 (P...
Post-translational modifications (PTMs) have been confirmed to be involved in multiple female reproductive events, but their role in physiological ovarian aging is far from elucidated. In this study, mice aged 3, 12 or 17 months (3M, 12M, 17M) were s...
Pearl color is the primary determinant of its value, and the mantle donor tissue (saibo) used in pearl culture plays a critical role in color formation. To elucidate the molecular mechanisms underlying nacre color, we performed comparative transcript...
Wstęp: Zmiany miąższowe w tomografii komputerowej płuc o wysokiej rozdzielczości (TKWR) obserwowane są u niektórych chorych na idiopatyczne tętnicze nadciśnienie płucne (IPAH), pomimo że nie mają oni śródmiąższowej choroby płuc. Najczęściej opisuje s...
Wprowadzenie: Postępowanie chirurgiczne stanowi podstawową metodę leczenia niedrobnokomórkowego raka płuca. Materiał i metody: W pracy przeprowadzono retrospektywną analizę skuteczności tego leczenia w grupie 431 chorych operowanych w Klinice Chirurg...