Transforming Veterinary Vaccinology: From Empirical Immunity to Scientific and Systems-Based Approaches

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Veterinary Vaccines".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 243

Special Issue Editors

Animal and Plant Quarantine Agency, Gimcheon-si 39660, Gyeongsangbuk-do, Republic of Korea
Interests: vaccine; adjuvant; immunostimulant; antigen-delivery system; innate-adaptive immunity; mucosal–systemic immunity; maternally-derived antibodies; infectious viral disease; systems immunology
Translational Health Engineering Research Center, Michigan Technological University, 109 Michigan St. NW, Grand Rapids, MI 49503, USA
Interests: animal model; drug discovery; epithelial cells; Infectious diseases; immunopathogenesis; molecular immunology; mother to child transmission; mucosal immunology; vaccine; viral disease; veterinary microbiology
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Special Issue Information

Dear Colleagues,

This Special Issue aims to highlight the evolving landscape of veterinary vaccinology within the scope of the journal, Vaccines, by addressing not only cellular and humoral immunity-based approaches but also the simultaneous induction of systemic and mucosal immunity and, importantly, their experimental and multidimensional validation through advanced immune profiling.

Recent advances in experimental and clinical immunology have enabled dynamic investigations of both innate and adaptive immune responses. While traditional vaccine platforms—including inactivated, live attenuated, and recombinant vaccines—remain integral to veterinary vaccine strategies, ongoing progress in precision vaccinology has introduced more comprehensive and data-informed methodologies.

In particular, multidimensional immune analysis, comprehensive immune profiling, and data-driven insights are increasingly valuable tools for elucidating vaccine-induced immune mechanisms and guiding rational vaccine design. These integrative approaches emphasize not only the prediction of immune outcomes but also their rigorous biological and experimental validation, bridging the gap between data and practical vaccine application.

In parallel, the development of novel adjuvants and advanced antigen delivery systems plays a crucial role in maximizing the efficacy of next-generation veterinary vaccines.

Topics of interest include the following:

- Vaccine antigen discovery and characterization using AI-based epitope prediction, omics-driven host–pathogen interactions, and experimental efficacy validation;

- Development and evaluation of traditional and next-generation vaccine platforms;

- Multidimensional immune response profiling and identification of correlates of protection, with an emphasis on the biological validation of vaccine candidates following their design;

- Field application studies and efficacy assessments of new veterinary vaccines;

- Comparative vaccinology exploring immunological differences across various animal species;

- Tailored vaccine strategies by species or disease.

We welcome original research articles, reviews, and short communications addressing both traditional and emerging infectious diseases in livestock, companion animals, and wildlife.

Dr. Min Ja Lee
Dr. Bapi Pahar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • veterinary vaccinology
  • precision vaccinology
  • multidimensional immune analysis
  • next-generation vaccine platform
  • novel adjuvants
  • comparative and translational vaccinology
  • biological validation

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Published Papers

This special issue is now open for submission.
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