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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Immunization Strategies for Animal Health

edited by Eva Calvo-Pinilla and

Alejandro Marin-Lopez

submission deadline 31 Oct 2025 | 8 articles | Viewed by 24899 | Submission Open

Keywords: vaccine immunology; virus; emerging infectious disease; animal health; public health; vaccination

(This special issue belongs to the Section Veterinary Vaccines)

Promoting Research, Development and Access to Vaccines to Address Global Inequities

edited by

Yangmu Huang

submission deadline 31 Oct 2025 | 7 articles | Viewed by 14911 | Submission Open

Keywords: research and development; communicable diseases; vulnerable population; medical countermeasures; vaccine-preventable diseases; innovative vaccines; vaccine hesitancy; health education; vaccination coverage rates; vaccination strategies

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Viral Vector-Based Vaccines and Therapeutics

edited by Sujit Pujhari

submission deadline 31 Oct 2025 | 6 articles | Viewed by 11348 | Submission Open

Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Vaccine Development for Swine Viral Pathogens

edited by Qingli Niu

submission deadline 31 Oct 2025 | 6 articles | Viewed by 10781 | Submission Open

Keywords: vaccine engineering; design; formulation; adjuvants; delivery; testing

(This special issue belongs to the Section Veterinary Vaccines)

Next-Generation Vaccines for Animal Infectious Diseases

edited by Yongwen Luo, Huiying Fan and Qing Wang

submission deadline 31 Oct 2025 | 6 articles | Viewed by 10302 | Submission Open

Keywords: LNP-mRNA vaccines; VLP vaccines; polymeric/inorganic nanoparticle vaccines; self-assembled protein vaccines; biomimetic nanoparticle vaccines; novel vector-based vaccines; new adjuvanted vaccines; nanovaccines

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines Targeting Dendritic Cells

edited by Ronald A. Backer and Björn E. Clausen

submission deadline 31 Oct 2025 | 4 articles | Viewed by 9169 | Submission Open

Keywords: vaccines; dendritic cells; antigen targeting; immune responses; adjuvant; cancer immunotherapy; T cell activation

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Acceptance and Hesitancy in Vaccine Uptake: 2nd Edition

edited by Sherri Sheinfeld Gorin

submission deadline 31 Oct 2025 | 9 articles | Viewed by 8531 | Submission Open

Keywords: vaccine acceptance; vaccine hesitancy; vaccine uptake; vaccination

(This special issue belongs to the Section Vaccines and Public Health)

New Approaches to Vaccine Development and Delivery

edited by

Antonio Carlos de Freitas

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7969 | Submission Open

Keywords: vaccines; formulation; vaccine delivery; yeast-based vaccines; surface display; yeast shell; delivery systems; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; virus-like particles (VLPs); quality control

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Humoral and Cellular Response After Vaccination

edited by Adrian Onu and Iuliana Caras

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5509 | Submission Open

Keywords: vaccine; infectious disease; humoral immunity; cellular immunity; innate immunity; trained immunity; pathogen; virus

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

HIV Vaccine Development and Clinical Trails

edited by Massimiliano Bissa

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5493 | Submission Open

Keywords: HIV vaccine; HIV vaccine clinical trial; HIV vaccine adjuvant; correlate of decreased HIV risk; HIV immunogen; broadly neutralizing antibodies

(This special issue belongs to the Section HIV Vaccines)

Advances in Allergy, Clinical Immunology, and Vaccines

edited by

Laura Franza

submission deadline 31 Oct 2025 | 1 articles | Viewed by 3883 | Submission Open

Keywords: immunology; allergology; allergy; autoimmunity; biomarkers; environment; pollution

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Novel Viral Vaccine and Molecular Immunology

edited by

Chang Li

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3824 | Submission Open

Keywords: viral infectious diseases; novel vaccines; immune mechanism

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Research in Vaccine Adjuvants: Innovations and Challenges

edited by Haibo Li and

Hongwu Sun

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2091 | Submission Open

Keywords: vaccine adjuvants; immune response enhancement; mucosal vaccine adjuvants; adjuvant safety and efficacy; new adjuvant materials; adjuvant mechanisms of action; adjuvant development challenges

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Pandemic Influenza Vaccination

edited by Francisco Nogareda and Shoshanna Goldin

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1372 | Submission Open

Keywords: pandemic influenza; vaccines; zoonotic influenza; influenza A/H5; preparedness; response

(This special issue belongs to the Section Influenza Virus Vaccines)

The Development of Recombinant and Subunit Vaccines Against Infectious Diseases

edited by

Abu Salim Mustafa

submission deadline 31 Oct 2025 | Viewed by 673 | Submission Open

Keywords: infectious diseases; vaccines; recombinant antigens; adjuvants

(This special issue belongs to the Section Vaccines against Infectious Diseases)

Bioengineering in Vaccine Design and Delivery

edited by

Massimo Zollo

submission deadline 1 Nov 2025 | 3 articles | Viewed by 9139 | Submission Open

Keywords: vaccine design; vaccine delivery; vaccine synthesis; vaccine carriers; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design

edited by Tony W. Ng and Steven A. Porcelli

submission deadline 1 Nov 2025 | 2 articles | Viewed by 4330 | Submission Open

Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Molecular Virology and Translational Research in Antiviral Vaccine Development

edited by

Safder Ganaie

submission deadline 20 Nov 2025 | Viewed by 369 | Submission Open

Keywords: molecular virology; antiviral development; vaccine design; host– pathogen interactions; viral entry and replication; immune evasion; structural virology; emerging and re-emerging viruses; zoonotic viruses

COVID Vaccines: Design, Development, and Immune Response Studies: 2nd Edition

edited by

Fabrizio Maggi

and

Licia Bordi

submission deadline 30 Nov 2025 | 24 articles | Viewed by 114453 | Submission Open

Keywords: COVID-19 vaccine; mucosal immunity; immune response; SARS-CoV-2; vaccine design

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Feature Papers of DNA and mRNA Vaccines

edited by

Jorge H. Leitão

submission deadline 30 Nov 2025 | 10 articles | Viewed by 53842 | Submission Open

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Advance Public Health Through Vaccination

edited by

Gianluca Voglino

, Maria Rosaria Gualano,

Giuseppina Lo Moro

and

Erica De Vita

submission deadline 30 Nov 2025 | 16 articles | Viewed by 41761 | Submission Open

Keywords: epidemiology; vaccination strategies; vaccine hesitancy; health equity; vulnerable population

(This special issue belongs to the Section Vaccines and Public Health)

Cancer Vaccines and Immunotherapy: Latest Advances, Limitations and Prospects

edited by

Eyad Elkord

and Afsheen Raza

submission deadline 30 Nov 2025 | 5 articles | Viewed by 14112 | Submission Open

Keywords: cancer; tumor microenvironment; tumor immunotherapy; therapy; cancer vaccines; combination therapy; tumor immune microenvironment; advanced therapies; biomarkers

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Vaccine Efficacy and Safety in Patients with Immune-Mediated Intestinal Diseases

edited by

Adi Lahat

and

Kassem Sharif

submission deadline 30 Nov 2025 | 5 articles | Viewed by 11116 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; celiac disease; vaccines; immune-mediated intestinal disease

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Advanced Concepts in Vaccines in Public Health

edited by Maria Elena Flacco

submission deadline 30 Nov 2025 | 4 articles | Viewed by 10015 | Submission Open

Keywords: vaccines; vaccine safety; vaccine efficacy; vaccine hesitancy; new vaccines; vaccine cost-effectiveness

(This special issue belongs to the Section Vaccines and Public Health)

Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition

edited by Juan Yang and Wei Wang

submission deadline 30 Nov 2025 | 4 articles | Viewed by 8360 | Submission Open

Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Advances in HIV Vaccine Development, 2nd Edition

edited by

Xueling Wu

submission deadline 30 Nov 2025 | 2 articles | Viewed by 6678 | Submission Open

Keywords: HIV; envelope glycoprotein; vaccine; adjuvant; antibody; neutralization; ADCC; ADCP; complement; cellular immune response

(This special issue belongs to the Section HIV Vaccines)

Intracellular Parasites: Immunology, Resistance, and Therapeutics

edited by

Rajesh Mani

and Nagendran Tharmalingam

submission deadline 30 Nov 2025 | 2 articles | Viewed by 4326 | Submission Open

Keywords: intracellular parasites; host– parasite interaction; chronic parasitic infections; innate and adaptive immunity; molecular genetics; immune evasion; antibiotic resistance; immune modulation; immunotherapy; vaccine development; biomaterials; nanoparticles

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

The Vaccine Development and Study of Swine Diseases

edited by

Chunhe Guo

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3332 | Submission Open

Keywords: swine diseases; viruses; vaccines; protection; control

(This special issue belongs to the Section Veterinary Vaccines)

Bacterial and Viral Infections: Current Challenges and Vaccine Innovations

edited by Dima El Safadi

submission deadline 30 Nov 2025 | 3 articles | Viewed by 3049 | Submission Open

Keywords: bacterial and viral infections; vaccine platforms; antimicrobial resistance; vaccine effectiveness; vaccine access and equity; global health

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

New Insights into Vaccination and Public Health: 2nd Edition

edited by

Paolo Castiglia

and

Antonella Arghittu

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2304 | Submission Open

Keywords: innovative vaccines; vaccine hesitancy; vaccination strategies; health communication; vaccine-preventable diseases

(This special issue belongs to the Section Vaccines and Public Health)

Animal Infectious Diseases and Vaccinology in One Health

edited by

Edith Rojas-Anaya

and Elizabeth Loza-Rubio

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2175 | Submission Open

Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses

(This special issue belongs to the Section Veterinary Vaccines)

Cost-Effectiveness of Vaccines and Public Health

edited by Sachin A. Silva

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1564 | Submission Open

Keywords: cost-effectiveness; public health value; vaccines; valuation; vaccination; immunization; benefit– cost; welfare; extended cost-effectiveness; QALYs

(This special issue belongs to the Section Vaccines and Public Health)

Advances in the Use of Nanoparticles for Vaccine Platform Development: 2nd Edition

edited by

Imran Saleem

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1071 | Submission Open

Keywords: nanoparticles; vaccine; immunotherapy; subunit vaccine; RNA vaccine; adjuvant; nanotechnology

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Vaccines Design Against Porcine Circovirus

edited by

Jianli Shi

Junki Maruyama

and

Takeshi Saito

submission deadline 30 Nov 2025 | Viewed by 600 | Submission Open

Keywords: porcine circovirus; vaccine; new adjuvants; evaluation method

(This special issue belongs to the Section Veterinary Vaccines)

Tuberculosis Diagnosis and Vaccines Research

edited by Shumaila Nida Javed Tunio

submission deadline 30 Nov 2025 | Viewed by 323 | Submission Open

Keywords: developing new diagnostic methods; new drugs; new vaccines for tuberculosis

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccines for Porcine Coronaviruses

edited by

Jung-Eun Park

submission deadline 1 Dec 2025 | Viewed by 446 | Submission Open

Keywords: porcine coronavirus; porcine epidemic diarrhea virus (PEDV); transmissible gastroenteritis virus (TGEV); porcine deltacoronavirus (PDCoV); swine acute diarrhea syndrome coronavirus (SADS-CoV); porcine respiratory coronavirus (PRCV); porcine hemagglutinating encephalomyelitis virus (PHEV); vaccine; immune response; protective efficacy

(This special issue belongs to the Section Veterinary Vaccines)

Vaccination and Public Health in the 21st Century

edited by

Evridiki Patelarou

Enkeleint A. Mechili

and

Athina E. Patelarou

submission deadline 20 Dec 2025 | 10 articles | Viewed by 15061 | Submission Open

Keywords: vaccines; public health; clinical vaccine research; immunization; health technology assessment; vaccine development

(This special issue belongs to the Section Vaccines and Public Health)

Nanotechnology-Based Vaccines for the Prevention of Infectious Diseases

edited by Wandi Zhu

submission deadline 20 Dec 2025 | Viewed by 370 | Submission Open

Keywords: infectious diseases; nanoparticle vaccines; nanovaccine delivery; immune responses; vaccine adjuvant; immune protection; mucosal immunity

Human Immune Responses to Infection and Vaccination

edited by

Alexander Batista-Duharte

and

Gabriel Cabrera

submission deadline 31 Dec 2025 | 9 articles | Viewed by 19349 | Submission Open

Keywords: vaccine immunogenicity; adjuvants; new generation of vaccines; vaccine development; immune regulation; translational vaccinology; system vaccinology; herd immunity; vaccine safety; correlates of protection

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Evaluation of Vaccine Efficacy, Safety and Immunogenicity Against Influenza, RSV and COVID-19

edited by

Roland Zahn

submission deadline 31 Dec 2025 | 5 articles | Viewed by 14811 | Submission Open

Keywords: influenza; respiratory syncytial virus (RSV); COVID-19; SARS-CoV-2; vaccines; immunogenicity; efficacy; safety; universal vaccine

(This special issue belongs to the Section Vaccine Advancement, Efficacy and Safety)

Health Technology Assessment of Vaccination: Strategies, Public Health and Values

edited by Maarten J. Postma, Jurjen Van der Schans and

Cornelis Boersma

submission deadline 31 Dec 2025 | 5 articles | Viewed by 11406 | Submission Open

Keywords: health technology assessment; population access vaccine studies; vaccination cost-effectiveness; vaccine hesitancy

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines Against Poultry Viruses

edited by

Xiuli Feng

submission deadline 31 Dec 2025 | 2 articles | Viewed by 9949 | Submission Open

Keywords: poultry and waterfowl; pigeons; wild birds; viral diseases; immunosuppressive disease; respiratory syndrome disease; poultry tumor diseases; immunoenhancers and adjuvants; genetically engineered vaccines; biosafety management of clinical veterinarians; antiviral drugs

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines for the Vulnerable Population

edited by

My Kieu Ha

submission deadline 31 Dec 2025 | 3 articles | Viewed by 8688 | Submission Open

Keywords: vaccines; vulnerable populations; infectious diseases; immunization

(This special issue belongs to the Section Vaccines and Public Health)

The Current Development of Glycoconjugate Vaccines for Infectious Diseases

edited by Fatme Mawas

submission deadline 31 Dec 2025 | 4 articles | Viewed by 8425 | Submission Open

Keywords: bacterial vaccines; polysaccharides; conjugate vaccines; carrier proteins

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccination and Public Health Strategy

edited by Shenglan Tang, Lance E. Rodewald and Taufique Joarder

submission deadline 31 Dec 2025 | 4 articles | Viewed by 7536 | Submission Open

Keywords: immunization Agenda 2030; vaccine equity; new vaccines introduction; sustainable immunization and financing; sustainable vaccine supply and procurement

(This special issue belongs to the Section Vaccines and Public Health)

Vaccines and Antibody-Based Therapeutics Against Infectious Disease

edited by Suman Kundu

submission deadline 31 Dec 2025 | 5 articles | Viewed by 7269 | Submission Open

Keywords: infectious disease; vaccine; antibody; therapy; agriculture; protection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Prevention of Human Papillomavirus (HPV) and Vaccination

edited by

Sara Boccalini

Paolo Bonanni

and

Angela Bechini

submission deadline 31 Dec 2025 | 3 articles | Viewed by 6850 | Submission Open

Keywords: HPV vaccination; screening; PAP test; HPV-DNA test; HPV vaccine coverage; vaccine hesitancy; promotion

(This special issue belongs to the Section Human Papillomavirus Vaccines)

The Development of mRNA Vaccines

edited by Minghui Yang, Yuming Li and Bo Hu

submission deadline 31 Dec 2025 | 3 articles | Viewed by 6333 | Submission Open

Keywords: nanoparticle delivery system; mRNA vaccines; infectious disease; tumor immunity; adjuvant

(This special issue belongs to the Section Nucleic Acid (DNA and mRNA) Vaccines)

Strategies for the Monitoring, Treatment, and Prevention of Mpox and Other Poxvirus Infections

edited by Patrick Obermeier and Susanne Buder

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6211 | Submission Open

Keywords: poxvirus; mpox; emerging infection; epidemiology; surveillance; vaccine; vaccine efficacy; immunity; one health; global health

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Recent Scientific Advances in Vaccines for Shigella

edited by Akamol Suvarnapunya, Kristen A Clarkson, Renee Laird and August Louis Bourgeois

submission deadline 31 Dec 2025 | 4 articles | Viewed by 6042 | Submission Open

Keywords: Shigella; vaccines; global health

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

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