Special Issues

Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioengineering Strategies for Developing Vaccines
edited by Chen Zhao and Jiayi Shu
submission deadline 30 Sep 2025 | Viewed by 288 | Submission Open
Keywords: vaccine platform; antigen design; targeted delivery; mRNA; nanoparticle; artificial intelligence
Vaccine Against Sexually Transmitted Diseases
edited by Weiming Tang
submission deadline 30 Sep 2025 | Viewed by 278 | Submission Open
Keywords: vaccination; sexually transmitted infections; HPV; HIV; syphilis; gonorrhea; and chlamydia; vaccine development; public health; epidemiology; health equity; preventive strategies
(This special issue belongs to the Section HIV Vaccines)
Innovations in Immunotherapy: Advancements in Cancer Vaccines and Immune Modulation
edited by and
submission deadline 30 Sep 2025 | Viewed by 205 | Submission Open
Keywords: multi-omics; cancer therapy; precision medicine; cancer vaccines
(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)
Virus-Like Particle (VLP) Vaccines Against Emerging Infectious Diseases—2nd Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 151 | Submission Open
Keywords: emerging infectious diseases (EIDs); virus-like particle (VLP); vaccines
(This special issue belongs to the Section Vaccine Adjuvants)
Factors Affecting Influenza Vaccine Uptake
edited by
submission deadline 20 Oct 2025 | 1 articles | Viewed by 1250 | Submission Open
Keywords: influenza; vaccines; coverage; uptake; hesitancy; risk groups
(This special issue belongs to the Section Influenza Virus Vaccines)
New Technology for Vaccines and Vaccine-Preventable Diseases
edited by
submission deadline 20 Oct 2025 | Viewed by 348 | Submission Open
Keywords: artificial intelligence in vaccines; big data in vaccine research; emerging infectious diseases; vaccine accessibility; vaccine delivery systems; vaccine efficacy and safety; vaccine-preventable diseases; vaccine technology
(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)
Viral Vector-Based and Other Vaccine Strategies for Poultry and Livestock
edited by Mathias Martins
submission deadline 20 Oct 2025 | Viewed by 341 | Submission Open
Keywords: vaccine strategies; viral vector-based vaccines; poultry; livestock; infectious diseases; immune responses; vaccine platforms; genetic engineering; veterinary medicine; antigen delivery
(This special issue belongs to the Section Veterinary Vaccines)
Vaccines Against Influenza and Other Respiratory Virus Infections
edited by
submission deadline 20 Oct 2025 | Viewed by 141 | Submission Open
Keywords: adjuvants; influenza; mucosal immunity; respiratory viral pathogens; vaccine effectiveness; vaccine safety
(This special issue belongs to the Section Influenza Virus Vaccines)
Immunization Strategies for Animal Health
edited by Eva Calvo-Pinilla and
submission deadline 31 Oct 2025 | 6 articles | Viewed by 15145 | Submission Open
Keywords: vaccine immunology; virus; emerging infectious disease; animal health; public health; vaccination
(This special issue belongs to the Section Veterinary Vaccines)
Viral Vector-Based Vaccines and Therapeutics
edited by Sujit Pujhari
submission deadline 31 Oct 2025 | 5 articles | Viewed by 7741 | Submission Open
Keywords: viral vectors; vaccine technology; gene therapy; immunization strategies; vector design; vaccine safety; vector-based therapeutics
(This special issue belongs to the Section Attenuated/Inactivated/Live and Vectored Vaccines)
Next-Generation Vaccines for Animal Infectious Diseases
edited by Yongwen Luo, Huiying Fan and Qing Wang
submission deadline 31 Oct 2025 | 5 articles | Viewed by 6778 | Submission Open
Keywords: LNP-mRNA vaccines; VLP vaccines; polymeric/inorganic nanoparticle vaccines; self-assembled protein vaccines; biomimetic nanoparticle vaccines; novel vector-based vaccines; new adjuvanted vaccines; nanovaccines
(This special issue belongs to the Section Veterinary Vaccines)
Vaccine Development for Swine Viral Pathogens
edited by Qingli Niu
submission deadline 31 Oct 2025 | 4 articles | Viewed by 5577 | Submission Open
Keywords: vaccine engineering; design; formulation; adjuvants; delivery; testing
(This special issue belongs to the Section Veterinary Vaccines)
Animal Diseases: Immune Response and Vaccines
edited by , José M. Rojas and
submission deadline 31 Oct 2025 | 4 articles | Viewed by 5487 | Submission Open
Keywords: immune responses; ruminants; vaccines; animal health
(This special issue belongs to the Section Veterinary Vaccines)
Vaccines Targeting Dendritic Cells
edited by Ronald A. Backer and Björn E. Clausen
submission deadline 31 Oct 2025 | 4 articles | Viewed by 5218 | Submission Open
Keywords: vaccines; dendritic cells; antigen targeting; immune responses; adjuvant; cancer immunotherapy; T cell activation
(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)
Humoral and Cellular Response after Vaccination
edited by Adrian Onu and Iuliana Caras
submission deadline 31 Oct 2025 | 2 articles | Viewed by 4715 | Submission Open
Keywords: vaccine; infectious disease; humoral immunity; cellular immunity; innate immunity; trained immunity; pathogen; virus
(This special issue belongs to the Section Cellular/Molecular Immunology)
Promoting Research, Development and Access to Vaccines to Address Global Inequities
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 4506 | Submission Open
Keywords: research and development; communicable diseases; vulnerable population; medical countermeasures; vaccine-preventable diseases; innovative vaccines; vaccine hesitancy; health education; vaccination coverage rates; vaccination strategies
(This special issue belongs to the Section Vaccine Efficacy and Safety)
HIV Vaccine Development and Clinical Trails
edited by Massimiliano Bissa
submission deadline 31 Oct 2025 | 2 articles | Viewed by 3928 | Submission Open
Keywords: HIV vaccine; HIV vaccine clinical trial; HIV vaccine adjuvant; correlate of decreased HIV risk; HIV immunogen; broadly neutralizing antibodies
(This special issue belongs to the Section HIV Vaccines)
Acceptance and Hesitancy in Vaccine Uptake: 2nd Edition
edited by Sherri Sheinfeld Gorin
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3371 | Submission Open
Keywords: vaccine acceptance; vaccine hesitancy; vaccine uptake; vaccination
(This special issue belongs to the Section Human Vaccines and Public Health)
Vaccine Efficacy and Safety in Transplant Recipients
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2980 | Submission Open
Keywords: transplant recipients; vaccination; kidney; heart; lung; stem cell transplants; safety; antibody response; efficacy
(This special issue belongs to the Section Vaccine Efficacy and Safety)
Novel Viral Vaccine and Molecular Immunology
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 2933 | Submission Open
Keywords: viral infectious diseases; novel vaccines; immune mechanism
(This special issue belongs to the Section Cellular/Molecular Immunology)
New Approaches to Vaccine Development and Delivery submission deadline 31 Oct 2025 | 2 articles | Viewed by 2626 | Submission Open
Keywords: vaccines; formulation; vaccine delivery; yeast-based vaccines; surface display; yeast shell; delivery systems; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; virus-like particles (VLPs); quality control
(This special issue belongs to the Section Vaccination Optimization)
Advances in Allergy, Clinical Immunology, and Vaccines
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1804 | Submission Open
Keywords: immunology; allergology; allergy; autoimmunity; biomarkers; environment; pollution
(This special issue belongs to the Section Clinical Immunology)
Research in Vaccine Adjuvants: Innovations and Challenges
edited by Haibo Li and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 957 | Submission Open
Keywords: vaccine adjuvants; immune response enhancement; mucosal vaccine adjuvants; adjuvant safety and efficacy; new adjuvant materials; adjuvant mechanisms of action; adjuvant development challenges
(This special issue belongs to the Section Vaccine Adjuvants)
Personalised Cancer Vaccines
edited by Andrew L. Coveler
submission deadline 31 Oct 2025 | 1 articles | Viewed by 900 | Submission Open
Keywords: peptide vaccines; mRNA vaccines; DNA vaccines; cancer vaccines
(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)
Infectious Diseases and Immunization in Animals
edited by , Ezgi Akdesir and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 583 | Submission Open
Keywords: animal vaccination; zoonotic diseases; One Health; host– pathogen interaction; veterinary immunology; emerging infectious diseases; antimicrobial resistance; vaccine development
(This special issue belongs to the Section Veterinary Vaccines)
The Development of Recombinant and Subunit Vaccines Against Infectious Diseases
edited by
submission deadline 31 Oct 2025 | Viewed by 491 | Submission Open
Keywords: infectious diseases; vaccines; recombinant antigens; adjuvants
(This special issue belongs to the Section Vaccines against Infectious Diseases)
Pandemic Influenza Vaccination
edited by Francisco Nogareda and Shoshanna Goldin
submission deadline 31 Oct 2025 | Viewed by 470 | Submission Open
Keywords: pandemic influenza; vaccines; zoonotic influenza; influenza A/H5; preparedness; response
(This special issue belongs to the Section Influenza Virus Vaccines)
Innovations Advancing Vaccine Preparedness and Response Capabilities to Counter Pandemic Influenza
edited by , Sam Lee, and
submission deadline 31 Oct 2025 | Viewed by 399 | Submission Open
Keywords: influenza vaccines; efficacy; vaccine uptake; rapid manufacturing; vaccine mechanism of action; alternative routes of administration; single-dose regimens
(This special issue belongs to the Section Influenza Virus Vaccines)
The Development of Peptide-Based Vaccines submission deadline 31 Oct 2025 | Viewed by 249 | Submission Open
Keywords: peptide antigens; vaccine design; immunogenicity; epitope mapping; adjuvants; multi-epitope vaccines; personalized peptide vaccines; vaccine delivery systems; computational vaccine design; synthetic peptides
Antiviral Immunity and Vaccine Development
edited by and Tao Yu
submission deadline 31 Oct 2025 | Viewed by 190 | Submission Open
Keywords: antiviral innate immunity; adaptive immune responses; viral pathogenesis; immune evasion; host– virus interactions; antiviral vaccine development; vaccine design; novel vaccine platforms; vaccine adjuvants; vaccines and therapeutics
(This special issue belongs to the Section Pathogens-host Immune Interface)
Nanomaterial Application in Vaccines
edited by and
submission deadline 31 Oct 2025 | Viewed by 47 | Submission Open
Keywords: nanomaterials; vaccine delivery; immunogenicity enhancement; tolerogenic nanovaccine; nanotechnology; vaccine stability; vaccine design; nanoparticles; immunization strategies; biotechnology in vaccines
Innovative Vaccines That Modulate the Immune System to Enhance Cancer Therapy
edited by
submission deadline 31 Oct 2025 | Viewed by 42 | Submission Open
Keywords: cancer vaccines; CAR T cell therapy; checkpoint-inhibitors; combination therapy; tumor microenvironment; tumor-infiltrating lymphocytes
(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)
Bioengineering in Vaccine Design and Delivery
edited by
submission deadline 1 Nov 2025 | 3 articles | Viewed by 7303 | Submission Open
Keywords: vaccine design; vaccine delivery; vaccine synthesis; vaccine carriers; virus-like particles
(This special issue belongs to the Section Attenuated/Inactivated/Live and Vectored Vaccines)
Immunobiology of Mycobacterium tuberculosis and Its Implication in Vaccine Design
edited by Tony W. Ng and Steven A. Porcelli
submission deadline 1 Nov 2025 | 2 articles | Viewed by 2886 | Submission Open
Keywords: Mycobacterium tuberculosis; polyfunctional T cells; antibodies; trained immunity; vaccination routes; non-human primates; persisters; auxotrophs; adjuvants
(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)
Molecular Virology and Translational Research in Antiviral Vaccine Development
edited by
submission deadline 20 Nov 2025 | Viewed by 36 | Submission Open
Keywords: molecular virology; antiviral development; vaccine design; host– pathogen interactions; viral entry and replication; immune evasion; structural virology; emerging and re-emerging viruses; zoonotic viruses
COVID Vaccines: Design, Development, and Immune Response Studies: 2nd Edition
edited by and
submission deadline 30 Nov 2025 | 16 articles | Viewed by 73245 | Submission Open
Keywords: COVID-19 vaccine; mucosal immunity; immune response; SARS-CoV-2; vaccine design
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Feature Papers of DNA and mRNA Vaccines
edited by
submission deadline 30 Nov 2025 | 9 articles | Viewed by 37575 | Submission Open
(This special issue belongs to the Section DNA and mRNA Vaccines)
Advance Public Health Through Vaccination
edited by , Maria Rosaria Gualano, and
submission deadline 30 Nov 2025 | 14 articles | Viewed by 24951 | Submission Open
Keywords: epidemiology; vaccination  strategies; vaccine hesitancy; health equity; vulnerable population
(This special issue belongs to the Section Human Vaccines and Public Health)
Cancer Vaccines and Immunotherapy: Latest Advances, Limitations and Prospects
edited by and Afsheen Raza
submission deadline 30 Nov 2025 | 4 articles | Viewed by 7289 | Submission Open
Keywords: cancer; tumor microenvironment; tumor immunotherapy; therapy; cancer vaccines; combination therapy; tumor immune microenvironment; advanced therapies; biomarkers
(This special issue belongs to the Section Cancer Vaccines and Immunotherapy)
Vaccine Efficacy and Safety in Patients with Immune-Mediated Intestinal Diseases
edited by and
submission deadline 30 Nov 2025 | 4 articles | Viewed by 6721 | Submission Open
Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; celiac disease; vaccines; immune-mediated intestinal disease
(This special issue belongs to the Section Vaccine Efficacy and Safety)
Advanced Concepts in Vaccines in Public Health
edited by and Maria Elena Flacco
submission deadline 30 Nov 2025 | 3 articles | Viewed by 5448 | Submission Open
Keywords: vaccines; vaccine safety; vaccine efficacy; vaccine hesitancy; new vaccines; vaccine cost-effectiveness
(This special issue belongs to the Section Human Vaccines and Public Health)
The Vaccine Development and Study of Swine Diseases
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1546 | Submission Open
Keywords: swine diseases; viruses; vaccines; protection; control
(This special issue belongs to the Section Veterinary Vaccines)
Population Immunity and Persistence to SARS-CoV-2 Induced by Infection and Vaccination, Protection Against New Infections and Implication for Further Vaccination: 2nd Edition
edited by Juan Yang and Wei Wang
submission deadline 30 Nov 2025 | 2 articles | Viewed by 1546 | Submission Open
Keywords: SARS-CoV-2; COVID-19; serology; population immunity; hybrid immunity; vaccination; antibody kinetics; cross-protection
(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)
Intracellular Parasites: Immunology, Resistance, and Therapeutics
edited by and Nagendran Tharmalingam
submission deadline 30 Nov 2025 | Viewed by 1231 | Submission Open
Keywords: intracellular parasites; host– parasite interaction; chronic parasitic infections; innate and adaptive immunity; molecular genetics; immune evasion; antibiotic resistance; immune modulation; immunotherapy; vaccine development; biomaterials; nanoparticles
(This special issue belongs to the Section Pathogens-host Immune Interface)
New Insights into Vaccination and Public Health: 2nd Edition submission deadline 30 Nov 2025 | 1 articles | Viewed by 1149 | Submission Open
Keywords: innovative vaccines; vaccine hesitancy; vaccination strategies; health communication; vaccine-preventable diseases
(This special issue belongs to the Section Human Vaccines and Public Health)
Cost-Effectiveness of Vaccines and Public Health
edited by Sachin A. Silva
submission deadline 30 Nov 2025 | Viewed by 598 | Submission Open
Keywords: cost-effectiveness; public health value; vaccines; valuation; vaccination; immunization; benefit– cost; welfare; extended cost-effectiveness; QALYs
(This special issue belongs to the Section Human Vaccines and Public Health)
Animal Infectious Diseases and Vaccinology in One Health
edited by and Elizabeth Loza-Rubio
submission deadline 30 Nov 2025 | 1 articles | Viewed by 562 | Submission Open
Keywords: vaccinology; productive animals; one health; infectious diseases; zoonoses
(This special issue belongs to the Section Veterinary Vaccines)
Vaccines Design Against Porcine Circovirus submission deadline 30 Nov 2025 | Viewed by 511 | Submission Open
Keywords: porcine circovirus; vaccine; new adjuvants; evaluation method
(This special issue belongs to the Section Veterinary Vaccines)
Factors Affecting and Strategies Enhancing the Willingness to Receive and Uptake of Seasonal Influenza Vaccination submission deadline 30 Nov 2025 | Viewed by 337 | Submission Open
Keywords: factors; strategies; willingness; uptake; seasonal influenza vaccination
(This special issue belongs to the Section Human Vaccines and Public Health)
Bacterial and Viral Infections: Current Challenges and Vaccine Innovations
edited by Dima El Safadi
submission deadline 30 Nov 2025 | Viewed by 324 | Submission Open
Keywords: bacterial and viral infections; vaccine platforms; antimicrobial resistance; vaccine effectiveness; vaccine access and equity; global health
(This special issue belongs to the Section Pathogens-host Immune Interface)
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