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Most Recent

  • Article
  • Open Access

19 December 2025

Background/Objectives: Associations between renal function, as measured by the estimated glomerular filtration rate (eGFR) or its decline (dGFR), and clinical parameters in patients with rheumatoid arthritis (RA) were evaluated using a retrospective...

  • Feature Paper
  • Review
  • Open Access
2 Citations
1,764 Views
46 Pages

17 November 2025

Background/Objectives: Autoimmune rheumatic diseases (AIRDs) are complex, heterogeneous, and relapsing–remitting conditions in which early diagnosis, flare prediction, and individualized therapy remain major unmet needs. This review aims to syn...

  • Case Report
  • Open Access
311 Views
6 Pages

10 November 2025

Introduction: In hemoglobinopathies, the amount of globin synthesis in hemoglobin (Hb) or its structure is altered. Clinical features are related to the rate and kind of structural aberrations. The heterozygous form of the Lepore syndrome resembles m...

  • Review
  • Open Access
2,424 Views
16 Pages

CAR-T Cell Therapy in Autoimmune Diseases: Promise, Progress, and Pitfalls

  • Alessandro Conforti,
  • Carlos Cifuentes-González,
  • Alarico Ariani,
  • Alberto Lo Gullo and
  • Rupesh Agrawal

31 October 2025

Background: Chimeric Antigen Receptor T-cell (CAR-T) cell therapy has revolutionized cancer treatment and is now being explored as a novel approach to treat refractory autoimmune diseases by targeting autoreactive immune components, especially B cell...

  • Article
  • Open Access
743 Views
15 Pages

Using Social Media Listening to Characterize the Flare Lexicon in Patients with Sjögren’s Disease

  • Chiara Baldini,
  • Maurice Flurie,
  • Zachary Cline,
  • Colton Flowers,
  • Coralie Peter Bouillot,
  • Linda J. Stone,
  • Lauren Dougherty,
  • Christopher DeFelice and
  • Maria Picone

26 September 2025

Background/Objectives: Sjögren’s disease (SjD) flares are incompletely understood. The patient perspective is critical to closing this gap. This retrospective social media listening (SML) study characterized the flare lexicon within the on...

  • Article
  • Open Access
2,433 Views
8 Pages

The Relationship Between Chronic Low Back Pain and Cigarette Smoking Habits in Patients Treated with Conservative Therapy

  • Fabiola Cappella,
  • Alessandro Di Rienzo,
  • Mario Chiapponi,
  • Valentina Liverotti and
  • Mauro Dobran

2 September 2025

Aim of the study: This paper focuses on the correlation of nicotine use with chronic lumbar back pain (CLBP). Methods: This is a cross-sectional observational study involving smoker and non-smoker patients with a diagnosis of chronic low back pain (C...

  • Review
  • Open Access
1,392 Views
16 Pages

25 August 2025

Living with inflammatory arthritis can have a significant impact; early identification, diagnosis and treatment has been shown to improve outcomes. The clinician working in settings where people with undiagnosed inflammatory arthritis may present for...

  • Article
  • Open Access
1,060 Views
11 Pages

21 August 2025

Background/Objectives: Chronic medical conditions are comorbid with psychological disorders, often attributed to the weight of managing persistent demands associated with debilitating illness. Lifestyle adjustments, physical pain, and costs of health...

  • Article
  • Open Access
1,348 Views
18 Pages

Unequal Burdens: Exploring Racial Disparities in Cardiovascular and SLE Outcomes Using National Inpatient Database 2016–2021

  • Freya Shah,
  • Siddharth Pravin Agrawal,
  • Darshilkumar Maheta,
  • Jatin Thukral and
  • Syeda Sayeed

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with significant racial and ethnic disparities in prevalence, disease severity, and outcomes. Cardiovascular complications, including pericarditis, myocarditis, valvular...

  • Review
  • Open Access
818 Views
11 Pages

Adipokines: Do They Affect the Osteochondral Unit?

  • Sergio Rosini,
  • Gianantonio Saviola,
  • Stefano Rosini,
  • Eleonora Baldissarro and
  • Luigi Molfetta

Obesity, characterized by excessive or abnormal accumulation of body fat, is associated with a range of metabolic and inflammatory diseases, including osteoarthritis (OA). In obese individuals, adipose tissue expansion—via adipocyte hypertrophy...

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Rheumato - ISSN 2674-0621