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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovative Anti-Toxoplasma Strategies: Pharmacology and Drug Development

edited by

Chunmei Jin

submission deadline 31 Jul 2026 | Viewed by 215 | Submission Open

Keywords: Toxoplasma gondii; drug discovery; pharmacology; antiparasitic agents; drug repurposing; novel therapeutics; toxoplasmosis; pharmacokinetics; drug resistance

(This special issue belongs to the Section Parasitic Pathogens)

New Horizons in Parasitic Infections Research

edited by

Rafaela Regina Fantatto

and

Kentaro Kato

submission deadline 31 Jul 2026 | Viewed by 215 | Submission Open

Keywords: parasitology; parasitic diseases; host– parasite interactions; parasitic infections

(This special issue belongs to the Section Parasitic Pathogens)

Bacterial Strategies to Subvert Innate Immune Defenses and Sustain Persistence

edited by

Rajesh Palanisamy

submission deadline 31 Jul 2026 | Viewed by 205 | Submission Open

Keywords: innate immune evasion; bacterial persistence; phagosome maturation; effector proteins nf-κ b signaling; inflammasome antagonism; biofilm formation; intracellular survival; cytokine modulation; host– pathogen interaction

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Infection and Immunity in Fish Models: Insights into Host Defense and Inflammation

edited by

Carla Lima

submission deadline 31 Jul 2026 | Viewed by 188 | Submission Open

Keywords: fish models; infection; immunity; host defense; inflammation

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Foodborne Pathogens: Genetic Profiling, Resistance, and Risk Assessment

edited by

Branko Velebit

and Urska Jamnikar-Ciglenecki

submission deadline 31 Jul 2026 | Viewed by 184 | Submission Open

Keywords: foodborne pathogens; genetic profiling; antimicrobial resistance; whole-genome sequencing; risk assessment

Antimicrobial Resistance in Klebsiella pneumoniae

edited by

Eduardo Rodriguez-Noriega

and

Dolores Alcantar-Curiel

submission deadline 31 Jul 2026 | Viewed by 182 | Submission Open

Keywords: Klebsiella pneumoniae; multidrug resistant; ESKAPE pathogen; carbapenem resistant; hypervirulent

(This special issue belongs to the Section Bacterial Pathogens)

Molecular Mechanisms of Stress Adaptation in Foodborne Pathogens

edited by

Mohamed K. Fakhr

and

Anand B. Karki

submission deadline 31 Jul 2026 | Viewed by 144 | Submission Open

Keywords: foodborne pathogens; stress adaptation; molecular mechanisms; genomics; transcriptomics; gene expression

Infectious Diseases of Domestic Animals: Epidemiology and Pathogenesis

edited by

Sergio Santos-Silva

and João Mesquita

submission deadline 31 Jul 2026 | Viewed by 128 | Submission Open

Keywords: domestic animals; infectious diseases; epidemiology; pathogenesis; zoonoses; surveillance; detection; prevention; emerging pathogens

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Focus on Cervicovaginal Health: Microbiome, Sexually Transmitted Infections, and Beneficial Microbes: 2nd Edition

edited by

Antonella Marangoni

and

Claudio Foschi

submission deadline 10 Aug 2026 | 3 articles | Viewed by 13806 | Submission Open

Keywords: vaginal microbiome; vaginal metabolome; lactobacilli; host– pathogen interactions; sexually transmitted infections; Chlamydia; gonorrhea; vaginal dysbiosis; vulvovaginal candidiasis; animal models

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Swine Infectious Diseases: Diagnostics, Pathogenesis, and Control Strategies

edited by

Luis G. Gimenez-Lirola

Jeffrey J. Zimmerman

and

Jesús Hernández

submission deadline 10 Aug 2026 | 7 articles | Viewed by 13299 | Submission Open

Keywords: swine; infectious diseases of swine; swine pathogens; diagnostics; pathogenesis; immune response; control strategies; surveillance; vaccines

Pathogenic Escherichia coli: Mechanisms of Virulence, Antimicrobial Resistance and Public Health Implications

edited by

Bogdan Nowicki

submission deadline 10 Aug 2026 | 2 articles | Viewed by 4953 | Submission Open

Keywords: pathogenic Escherichia coli; virulence factors; antimicrobial resistance; gastrointestinal infections; public health

(This special issue belongs to the Section Bacterial Pathogens)

Immune Pathways and Mechanisms Involved in Viral Infections

edited by

Celina Monteiro Abreu

, Lendel Correia Da Costa, Ana Carolina Soares and

Isadora Alonso Corrêa

submission deadline 10 Aug 2026 | 1 articles | Viewed by 1512 | Submission Open

Keywords: viral infections; host– virus interactions; immune pathways; viral evasion; antiviral therapies; vaccine development

(This special issue belongs to the Section Viral Pathogens)

Mycoplasmas in Respiratory Tract Infections of Cattle: 2nd Edition

edited by

Katarzyna Dudek

submission deadline 10 Aug 2026 | 1 articles | Viewed by 1145 | Submission Open

Keywords: mycoplasmas; respiratory infections; bovine respiratory disease; immunology

Veterinary Parasitology: Advances in Diagnosis and Control

edited by

Laura Williams

and Timothy Wu

submission deadline 10 Aug 2026 | Viewed by 258 | Submission Open

Keywords: veterinary parasitology; diagnostic parasitology; host– parasite interactions; parasite control strategies

(This special issue belongs to the Section Parasitic Pathogens)

Laboratory Diagnostics in Epidemiological Diseases Caused by Animal Pathogens

edited by

Tomasz Grenda

and

Karol Stasiak

submission deadline 15 Aug 2026 | 4 articles | Viewed by 8355 | Submission Open

Keywords: animal pathogens; laboratory diagnostics; epidemiology; infections; toxins

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Zoonoses in Portugal: Epidemiology and Emerging Challenges in an Atlantic-Mediterranean Context

edited by

Ana Cláudia Coelho

João R. Mesquita

and

Luís Cardoso

submission deadline 15 Aug 2026 | Viewed by 269 | Submission Open

Keywords: epidemiology and monitoring of zoonotic diseases in Portugal; new and returning zoonoses in Atlantic– mediterranean ecosystems; vector-borne and climate-sensitive zoonotic infestations; wildlife; livestock; and companion animals as hosts of zoonotic pathogens; environmental and foodborne zoonoses; including marine-related risks; antimicrobial resistance in zoonotic pathogens

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Antiviral Strategies Against Mpox

edited by Julia Tree, Amanda Horton, David Ulaeto, Isobel Stokes and Amanda Phelps

submission deadline 15 Aug 2026 | Viewed by 248 | Submission Open

Keywords: Mpox virus; antiviral; vaccine; medical countermeasure; therapeutic; public health

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Research on Plant Microbial Pathogens: Interactions, Diagnostics and Sustainable Management

edited by Ahmad Ali

submission deadline 15 Aug 2026 | Viewed by 190 | Submission Open

Keywords: plant diseases; soil-borne pathogens; pathogen detection and diagnostics; microbiome interactions

Advanced Antimicrobial Agents: Combatting Multi-Drug Resistant Bacterial Infections

edited by Nachiket Vaze

submission deadline 20 Aug 2026 | 10 articles | Viewed by 22165 | Submission Open

Keywords: multi-drug resistance; antimicrobial susceptibility; nanoformulations; UV disinfection; antibiotic synergy

(This special issue belongs to the Section Bacterial Pathogens)

Coxiella burnetii: The Host Immune Response, Host–Pathogen Interaction and Pathogenesis

edited by

Guoquan Zhang

and Erin J. Van Schaik

submission deadline 20 Aug 2026 | 4 articles | Viewed by 8523 | Submission Open

Keywords: Coxiella burnetii; host immune responses; host– Coxiella interaction; vaccine development; pathogenesis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

New Insights into Zoonotic Intracellular Pathogens

edited by

Tarka Raj Bhatta

, Stephen Graves and

John Stenos

submission deadline 20 Aug 2026 | 2 articles | Viewed by 6053 | Submission Open

Keywords: zoonotic intracellular pathogens; bacteria; viruses; sequencing; virulence factors; immune system; vaccine development; diagnostic tools; one health

Emerging and Neglected Zoonotic Pathogens in Companion Animals

edited by Olga Szalus̈-Jordanow

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2366 | Submission Open

Keywords: zoonotic pathogens; host– pathogen interactions; companion animals; one Health; antimicrobial resistance; emerging infectious diseases; interspecies transmission; molecular epidemiology; pathogen surveillance

(This special issue belongs to the Section Emerging Pathogens)

Malaria in a Changing World

edited by

Harry Tagbor

and

Luiz Shozo Ozaki

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1450 | Submission Open

Keywords: malaria; climate change; vector-borne disease; global health; drug resistance; health systems; technological innovation; epidemiological transition; social determinants of health; one health

(This special issue belongs to the Section Parasitic Pathogens)

Pathogen-Integrated Non-Coding Sequences: Regulatory Roles in Infection, Immune Response, and Disease

edited by

Xiao-Ou Zhang

submission deadline 20 Aug 2026 | Viewed by 440 | Submission Open

Keywords: non-coding sequences; pathogen genome integration; immune response; lymphocyte subpopulations; diagnostic biomarkers; tuberculosis; HPV-related cancers; cervical cancer; pathogen-associated cancers; infectious diseases

Water-Borne Pathogens: 2nd Edition

edited by

María José Figueras

and

Ana Fernández-Bravo

submission deadline 20 Aug 2026 | Viewed by 294 | Submission Open

Keywords: water-borne pathogens; epidemiology; virulence; immune response

The Oral–Systemic Microbiome Axis: From Local Dysbiosis to Multi-Organ Disease Pathogenesis

edited by

David R. Drake

submission deadline 20 Aug 2026 | Viewed by 284 | Submission Open

Keywords: oral microbiome; dysbiosis; microbial diversity; pathobiont; commensal bacteria; oral biofilm; periodontitis; dental caries; oral cancer; gingivitis; cardiovascular disease; diabetes; Alzheimer's disease; rheumatoid arthritis; cancer; obesity; 16S rRNA sequencing; metagenomics; metabolomics; machine learning; biomarkers; oral– systemic health; dentistry; cardiology; neurology; gastroenterology; precision medicine

Thinking Inside the Host: Strategies of Facultative Intracellular Bacteria

edited by

Cecilia Ambrosi

submission deadline 25 Aug 2026 | 1 articles | Viewed by 2064 | Submission Open

Keywords: facultative intracellular bacteria; eukaryotic hosts; pathogens invade; pathogens persist; pathogens disseminate

(This special issue belongs to the Section Bacterial Pathogens)

One Health—Viral Zoonosis: Epidemiology, Pathogenesis, Surveillance and Early Warning, Novel Prevention and Control Technologies

edited by Xuejie Yu, Xuexing Zheng and Lina Yan

submission deadline 30 Aug 2026 | 2 articles | Viewed by 4153 | Submission Open

Keywords: viral zoonoses; epidemiology; pathogenesis; surveillance; prevention and control technologies

(This special issue belongs to the Section Viral Pathogens)

Viral Infections and Their Effects on the Central Nervous System (CNS), 2nd Edition

edited by Rajnish S. Dave, Josué Pérez-Santiago and

Dianne Langford

submission deadline 30 Aug 2026 | 1 articles | Viewed by 1955 | Submission Open

Keywords: virus; CNS; COVID-19; HIV-1; neuroinflammation

(This special issue belongs to the Section Viral Pathogens)

Tick-Borne Pathogens: Advanced Identification, Characterization, Transmission, and Prevalence Studies

edited by

Sara Savić

submission deadline 31 Aug 2026 | 7 articles | Viewed by 16012 | Submission Open

Keywords: ticks; tick-borne pathogens; identification; characterization; transmission; prevalence; host interactions; zoonoses

(This special issue belongs to the Section Ticks)

Exploring Natural Products as Antiparasitic Agents: Efficacy Against Parasites of Veterinary and Public Health Significance

edited by

Agustín Olmedo-Juárez

and

Elke Von Son-De Fernex

submission deadline 31 Aug 2026 | 9 articles | Viewed by 13934 | Submission Open

Keywords: plant extracts; phytochemicals; fungi; parasites; anthelmintics; secondary metabolites; natural compounds; ethnoveterinary

(This special issue belongs to the Section Parasitic Pathogens)

The Epidemiology, Control, and Global Impact of African Swine Fever and Other Transboundary Swine Diseases

edited by

Mary-Louise Penrith

Juanita Van Emmenes

and

Pam Dachung Luka

submission deadline 31 Aug 2026 | 4 articles | Viewed by 9002 | Submission Open

Keywords: African swine fever; classical swine fever; PRRS; porcine coronaviruses; management

(This special issue belongs to the Section Viral Pathogens)

Pathogenesis, Epidemiology, and Control of Animal Influenza Viruses—2nd Edition

edited by Christina M. Leyson and

Silvia Carnaccini

submission deadline 31 Aug 2026 | 2 articles | Viewed by 6156 | Submission Open

Keywords: avian influenza; swine influenza; equine influenza; animal influenza; influenza epidemiology; pathogenesis; influenza vaccines; influenza phylogenetics.

(This special issue belongs to the Section Viral Pathogens)

Human Cytomegalovirus: From Molecular Pathogenesis to Therapeutic Innovations

edited by

Gaëtan Ligat

and Alexia Damour

submission deadline 31 Aug 2026 | 6 articles | Viewed by 5402 | Submission Open

Keywords: human cytomegalovirus; therapeutic strategies and vaccines; glioblastoma; congenital infection; immunocompromised

(This special issue belongs to the Section Viral Pathogens)

The Interplay of Microbiota and Polyomaviruses in Human Health and Disease

edited by

Valeria Pietropaolo

submission deadline 31 Aug 2026 | 2 articles | Viewed by 5101 | Submission Open

Keywords: human polyomaviruses (HPyVs); microbiota; co-infection patterns; cancer; diagnostic markers; cellular pathways; immunosuppression

(This special issue belongs to the Section Viral Pathogens)

Parasitic Diseases in Livestock: Advances in Diagnostics, Understanding and Control

edited by

César Cristiano Bassetto

and Ana Cláudia Alexandre de Albuquerque

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4120 | Submission Open

Keywords: gastrointestinal nematodes; livestock; parasitic diseases; parasites; sheep; cattle; host– parasite interaction

(This special issue belongs to the Section Parasitic Pathogens)

Toxoplasmosis in Humans and Animals

edited by

Coralie L'Ollivier

and

Younes Laidoudi

submission deadline 31 Aug 2026 | 4 articles | Viewed by 4007 | Submission Open

Keywords: Toxoplasma gondii; zoonosis; congenital toxoplasmosis; applied epidemiology; One Health; host– pathogen interaction; diagnostic methods; foodborne transmission

(This special issue belongs to the Section Parasitic Pathogens)

Infectious Diseases in Pediatric Populations: Clinical Challenges and Emerging Perspectives

edited by Piero Pavone,

Roberta Leonardi

and Manuela Lo Bianco

submission deadline 31 Aug 2026 | 2 articles | Viewed by 3008 | Submission Open

Keywords: pediatric infectious diseases and immune responses; post-infectious syndromes; diagnosis and treatment of pediatric infectious diseases; pediatric microbiome; viral; fungal; and bacterial infections in children

Advances in Yersinia: Pathogenesis, Host Response, Epidemiology and Ecology of Diseases, Prevention, and Treatment

edited by

Deborah Anderson

and Vladimir Motin

submission deadline 31 Aug 2026 | 5 articles | Viewed by 2466 | Submission Open

Keywords: Yersinia pathogenesis; host response; plague vaccines; Yersinia genomics; zoonotic transmission; emerging and reemerging yersiniosis; plague; vaccines; flea transmission

(This special issue belongs to the Section Bacterial Pathogens)

From Acute Infection to Chronic Sequelae: A Research Trajectory in Viral Infections Disease Management

edited by

Olga Adriana Caliman-Sturdza

and

Roxana Gheorghita

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1859 | Submission Open

Keywords: viral pathogenesis; post-acute infection syndromes; chronic sequelae; long-term outcomes; disease management

(This special issue belongs to the Section Viral Pathogens)

Host–Microbiota Interactions in Periodontal Disease: Pathogenic Invasion, Immune Evasion, and Commensal Defense

edited by

Giancarlo A. Cuadra

and

Dominic L. Palazzolo

submission deadline 31 Aug 2026 | 1 articles | Viewed by 651 | Submission Open

Keywords: oral commensal streptococci; oral pathogens; oral epithelial tissues; pathogenic invasion; host defense; immune evasion; periodontal disease; external factors associated with periodontal disease; therapeutic strategies for periodontal disease

HIV Reservoir Dynamics and Latency Mechanisms Under Current and Emerging Antiviral Strategies

edited by

Chen Zhang

and

Prasanta K. Dash

submission deadline 31 Aug 2026 | Viewed by 551 | Submission Open

Keywords: HIV reservoirs; HIV latency mechanisms; reservoir persistence; reservoir dynamics prediction; HIV therapies; reservoir targeting; reservoir eradication strategies; new gene-editing delivery vehicles

(This special issue belongs to the Section Viral Pathogens)

Regulation of Host Innate Immunity During Pathogens Infection

edited by

Xin Ran

submission deadline 31 Aug 2026 | Viewed by 229 | Submission Open

Keywords: pathogens; bacterial pathogens; pattern-recognition receptors; innate immune circuits; gram-negative and gram-positive infections; inflammasome activation

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Transmission and Control of Antimicrobial-Resistant Pathogens in Animal-Derived Foods: Molecular Mechanisms from Farm to Fork

edited by

Martina Rega

and

Mauro Conter

submission deadline 31 Aug 2026 | Viewed by 160 | Submission Open

Keywords: antimicrobial resistance; food safety; molecular mechanisms; One Health; veterinary public health

Innovative Strategies Against Resistant Bacterial Infections: Bacteriophage Therapy

edited by

Katarzyna Kosznik-Kwaśnicka

Agnieszka Necel

and

Byeonghwa Jeon

submission deadline 1 Sep 2026 | 1 articles | Viewed by 458 | Submission Open

Keywords: bacteriophage therapy; antimicrobial resistance; multidrug-resistant bacteria; phage– antibiotic synergy; phage-derived enzymes; biofilms; alternative antimicrobials; phage genomics

(This special issue belongs to the Section Bacterial Pathogens)

Immunopathogenesis of Influenza and Respiratory Syncytial Virus Infection

edited by

Norbert J. Roberts, Jr.

submission deadline 10 Sep 2026 | 2 articles | Viewed by 5610 | Submission Open

Keywords: influenza virus; respiratory syncytial virus; viral pathogenesis; monocytes– macrophages; lymphocytes

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Epidemiology, Diagnostics, and Therapeutics of High-Risk Human Papillomavirus (HPV) Infections

edited by Zhengchun Lu and Guang Fan

submission deadline 10 Sep 2026 | 2 articles | Viewed by 1667 | Submission Open

Keywords: high-risk HPV; HPV-associated diseases; screening and diagnostics; HPV epidemiology; therapeutic and preventive strategies

(This special issue belongs to the Section Viral Pathogens)

Virulence and Resistance Mechanisms in Multidrug-Resistant Gram-Negative Bacteria: 2nd Edition

edited by

Steven E. Fiester

and

William Penwell

submission deadline 10 Sep 2026 | 1 articles | Viewed by 709 | Submission Open

Keywords: antibiotic resistance mechanisms; MDR gram-negative bacteria; gram-negative nosocomial infections; carbapenem-resistant Enterobacteriaceae infections; bacterial infection

(This special issue belongs to the Section Bacterial Pathogens)

Viral Infection and Antiviral Drug

edited by Hiya Lahiri and

Jochen Bodem

submission deadline 10 Sep 2026 | Viewed by 245 | Submission Open

Keywords: viral diseases; structural analysis; antivirals; artificial intelligence

(This special issue belongs to the Section Viral Pathogens)

Surveillance, Prevention and Control of Sexually Transmitted Infections

edited by

Miguel A. Sánchez-Alemán

submission deadline 15 Sep 2026 | 2 articles | Viewed by 2488 | Submission Open

Keywords: sexually transmitted infections; syphilis; herpes; papillomavirus; HIV; sexual health; epidemiology; reproductive health; prevention; diagnosis; treatment

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