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Pathogens publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Products Chemistry: Innovation and New Frontiers in Antiparasitic Therapies

edited by Raymundo Alejandro Pérez Hernández,

Ramiro Quintanilla-Licea

Eduardo Sánchez-García

and

Joel Horacio Elizondo Luevano

submission deadline 15 Dec 2025 | 1 articles | Viewed by 914 | Submission Open

Keywords: natural products; antiparasitic activity; medicinal plants; microorganisms; marine organisms; animal byproducts; in vitro; in vivo; and in silico approaches; natural products chemistry; pharmacognosy; innovative therapies; ethnopharmacology; micro-nanoparticles; targeted therapy; epidemiology; purification and extraction; ligand& ndash; receptor activity

(This special issue belongs to the Section Parasitic Pathogens)

Parasites of Wildlife and Livestock: Recent Progress and Future Challenges

edited by

Beatriz Brener

submission deadline 15 Dec 2025 | Viewed by 369 | Submission Open

Keywords: helminths; protozoan; ectoparasites; animals

(This special issue belongs to the Section Parasitic Pathogens)

Vector-Borne and Zoonotic Viral Infections

edited by

Nariman Shahhosseini

submission deadline 15 Dec 2025 | Viewed by 285 | Submission Open

Keywords: vector-borne viruses; genomics; arbovirus; zoonosis; pathogenesis; epidemiology

(This special issue belongs to the Section Viral Pathogens)

Emerging and Re-Emerging Avian Influenza Viruses in Wildlife

edited by

Klaudia Chrzastek

submission deadline 15 Dec 2025 | Viewed by 193 | Submission Open

Keywords: avian influenza virus; HPAIV; LPAIV; wildlife; surveillance; epidemiology; phylogenetics; next-generation sequencing

(This special issue belongs to the Section Viral Pathogens)

Pathogenic Escherichia coli: Mechanisms of Virulence, Antimicrobial Resistance and Public Health Implications

edited by

Bogdan Nowicki

submission deadline 15 Dec 2025 | Viewed by 187 | Submission Open

Keywords: pathogenic Escherichia coli; virulence factors; antimicrobial resistance; gastrointestinal infections; public health

(This special issue belongs to the Section Bacterial Pathogens)

Microbial Mechanisms and Host Interactions in Oral Diseases: Implications for Pathogenesis, Prevention, and Novel Therapeutics

edited by

Shankargouda B. Patil

submission deadline 15 Dec 2025 | Viewed by 177 | Submission Open

Keywords: oral diseases; dental caries; periodontal disease; microbial biofilms; innovative therapeutics

Understanding the Dynamics of HIV Reservoirs Is Fundamental for Finding a Potential HIV Cure

edited by Germán Gornalusse and Sulggi Lee

submission deadline 15 Dec 2025 | Viewed by 171 | Submission Open

Keywords: HIV reservoir; HIV latency; HIV cure

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Occupational Exposure to Zoonotic Vector-Borne Diseases: Risks, Prevention, and Emerging Challenges

edited by

Angela Stufano

submission deadline 15 Dec 2025 | Viewed by 150 | Submission Open

Keywords: zoonotic vector-borne diseases; ZVBDs; preventive strategies

New Insights into Host-Vector-Pathogen Interactions

edited by Eva Špitalská and

Mária Kazimírová

submission deadline 15 Dec 2025 | Viewed by 126 | Submission Open

Keywords: vector-borne viruses; vector-borne bacteria; ticks; mosquitoes; vectors

Dynamics of Vector-Borne Infections

edited by Eduardo Massad

submission deadline 15 Dec 2025 | Viewed by 104 | Submission Open

Keywords: mathematical models; vector-borne infections; population dynamics

(This special issue belongs to the Section Viral Pathogens)

Bacterial Pathogens-Host Interface in Cystic Fibrosis

edited by

Roberto Rosales-Reyes

submission deadline 15 Dec 2025 | Viewed by 103 | Submission Open

Keywords: cystic fibrosis; bacterial pathogens; bacterial adaptation; bacterial pathogenesis; cell– host interaction; immune response; modulators effect; antimicrobial resistance

(This special issue belongs to the Section Bacterial Pathogens)

Diagnostic Challenges in Joint Infections: From Culture to Molecular Techniques

edited by Jochen Hofstaetter

submission deadline 15 Dec 2025 | Viewed by 90 | Submission Open

Keywords: joint infections; molecular diagnostics; periprosthetic joint infections

Pathogen-Integrated Non-Coding Sequences: Regulatory Roles in Infection, Immune Response, and Disease

edited by

Xiao-Ou Zhang

submission deadline 15 Dec 2025 | Viewed by 89 | Submission Open

Keywords: non-coding sequences; pathogen genome integration; immune response; lymphocyte subpopulations; diagnostic biomarkers; tuberculosis; HPV-related cancers; cervical cancer; pathogen-associated cancers; infectious diseases

Advancements in Understanding and Managing Human Herpesvirus Infections and Diseases

edited by

Francesco Broccolo

and

Jing Wu

submission deadline 15 Dec 2025 | Viewed by 85 | Submission Open

Keywords: herpesviruses; antiviral therapies; immunopathogenesis; treatment; vaccine

(This special issue belongs to the Section Viral Pathogens)

Antiviral Strategies Against Mpox

edited by Julia Tree, Amanda Horton, David Ulaeto, Isobel Stokes and Amanda Phelps

submission deadline 15 Dec 2025 | Viewed by 64 | Submission Open

Keywords: Mpox virus; antiviral; vaccine; medical countermeasure; therapeutic; public health

(This special issue belongs to the Section Vaccines and Therapeutic Developments)

Immunopathogenesis of Influenza and Respiratory Syncytial Virus Infection

edited by

Norbert J. Roberts, Jr.

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2091 | Submission Open

Keywords: influenza virus; respiratory syncytial virus; viral pathogenesis; monocytes– macrophages; lymphocytes

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Understanding Microbial Keratitis: Basic Science, Epidemiology, Diagnosis and Management

edited by

Chameen Samarawickrama

, Vannessa Leung, Yashar Seyed Razavi and Samantha Bobba

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1975 | Submission Open

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

New Insights on Parasites as Bioindicators

edited by Jaqueline Bianque de Oliveira and Müller Ribeiro Andrade

submission deadline 20 Dec 2025 | Viewed by 420 | Submission Open

Keywords: parasitic ecology; habitat change; bioindicators; emerging infectious diseases; zoonoses; wildlife; One Health

(This special issue belongs to the Section Parasitic Pathogens)

Epidemiology of Human Infectious Diseases During Health Crises in Low- and Middle-Income Countries

edited by

Samia Boussaa

and Youssef Ikken

submission deadline 20 Dec 2025 | Viewed by 143 | Submission Open

Keywords: epidemiology of infectious disease; COVID19; measles; tuberculosis; malaria; VIH; bacterial meningitis; infectious diseases; antibioresistance

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Pathogen–Host Interactions: Death, Defense, and Disease

edited by Hongyan Guo and Heather S. Koehler

submission deadline 20 Dec 2025 | Viewed by 94 | Submission Open

Keywords: host– pathogen interaction; immune evasion; virulence factors; antimicrobial resistance; zoonosis

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Host Interaction and Immune Modulation of RNA Viruses

edited by

Zhenlong Liu

and

Sonia Navas-Martin

submission deadline 22 Dec 2025 | 1 articles | Viewed by 1762 | Submission Open

Keywords: RNA viruses; viral immunology; antiviral therapy development

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Dairy Cattle Health: Mastitis, Milk Quality, and Antimicrobial Resistance from a One Health Perspective

edited by

Alfonso Zecconi

submission deadline 30 Dec 2025 | 1 articles | Viewed by 939 | Submission Open

Keywords: udder immune defenses; inflammation; milk leukocytes; mastitis control; One Health approach; immune components in milk

(This special issue belongs to the Section Bacterial Pathogens)

Current Challenges in Veterinary Virology

edited by

Magdalena Materniak-Kornas

Marzena Rola-Łuszczak

and

Grzegorz Woźniakowski

submission deadline 31 Dec 2025 | 14 articles | Viewed by 21300 | Submission Open

Keywords: virus; veterinary; diagnostics; host interaction; epidemiology; evolution

(This special issue belongs to the Section Viral Pathogens)

Detection of Indoor Fungi: Part II

edited by

Donát Magyar

submission deadline 31 Dec 2025 | 5 articles | Viewed by 12800 | Submission Open

Keywords: molds; fungi; indoor environment; indoor air quality and molds; mycotoxins; fungal MVOCs; fungal allergens; pathogenic fungi in the indoor environment; biodeterioration by fungi in the indoor environment; aeromycology; fungal diversity

(This special issue belongs to the Section Fungal Pathogens)

New Insights into Viral Pathogenesis, Host Immune Responses and Immunotherapies

edited by

Dawei Zhou

, Taiwei Li and

Theresa Chang

submission deadline 31 Dec 2025 | 6 articles | Viewed by 8514 | Submission Open

Keywords: virus-host interaction; viral replication; viral pathogenesis; host immune responses; antiviral immunotherapies

(This special issue belongs to the Section Immunological Responses and Immune Defense Mechanisms)

Emergence and Re-Emergence of Animal Viral Diseases

edited by

Zaheer Ahmed

submission deadline 31 Dec 2025 | 5 articles | Viewed by 4991 | Submission Open

Keywords: animal viral diseases; virus emergence; molecular characterization; novel assays; whole-genome sequencing (WGS); foreign animal diseases; disease surveillance and monitoring; pathogen evolution; diagnostic innovations; epidemiological trends

(This special issue belongs to the Section Emerging Pathogens)

Host-Pathogen Interactions During Pathogenic Human Coronavirus Infection: 2nd Edition

edited by

Masfique Mehedi

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3421 | Submission Open

Keywords: COVID-19; spike; mRNA; goblet cell; viremia; pneumonia; convalescent; antibody; transmission

(This special issue belongs to the Section Viral Pathogens)

Molecular Detection and Characterisation of Viral Pathogens: 2nd Edition

edited by

Armanda Bastos

and David P. Tchouassi

submission deadline 31 Dec 2025 | 3 articles | Viewed by 2827 | Submission Open

Keywords: diversity; evolution; genomics; molecular diagnostics; molecular epidemiology; vaccines; vector-borne; virulence; zoonotic

(This special issue belongs to the Section Viral Pathogens)

Laboratory Diagnostics in Epidemiological Diseases Caused by Animal Pathogens

edited by

Tomasz Grenda

and

Karol Stasiak

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2611 | Submission Open

Keywords: animal pathogens; laboratory diagnostics; epidemiology; infections; toxins

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Acinetobacter baumannii: An Emerging Pathogen

edited by

Suresh G. Joshi

and

Robert A. Bonomo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2546 | Submission Open

Keywords: Acinetobacter baumannii; Acinetobacter baumannii virulence factors; animal model(s) of infection; antimicrobial agents; and their synergism; carbapenem resistance; immune response and antibody evaluation; multi-drug resistance; nosocomial infection; surgical and wound infection; transferable genes; vaccine and vaccine development

(This special issue belongs to the Section Bacterial Pathogens)

Hepatitis E Virus (HEV) Infection Among Humans and Animals: Epidemiology, Clinical Characteristics, Treatment and Prevention—2nd Edition

edited by

Jelena Prpić

and

Magdalena Baymakova

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1631 | Submission Open

Keywords: seroprevalence; molecular analysis; clinical characteristics; prevention; treatment

(This special issue belongs to the Section Viral Pathogens)

HIV/AIDS Epidemiology, Prevention and Diagnostics: Current State of Research

edited by

Lars Henning

and Maria Castellanos

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1482 | Submission Open

Keywords: HIV; AIDS; diagnostics; epidemiology; prevention

(This special issue belongs to the Section Epidemiology of Infectious Diseases)

Tick-Borne Pathogens and Their Impact on Human and Animal Health

edited by

and

Aleksandar Cvetkovikj

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1429 | Submission Open

Keywords: tick-borne diseases; zoonotic pathogens; Lyme borreliosis; emerging tick-borne pathogens; Rickettsia; vector biology; disease transmission; public health impact; animal health; tick control and prevention; the control and prevention of tick-borne diseases

(This special issue belongs to the Section Ticks)

Drug Resistant Pathogens: Diagnosis, Treatment, and Global Health Implications

edited by

Giuseppe Pipitone

Alberto Enrico Maraolo

and

Luigi Principe

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1405 | Submission Open

Keywords: antibiotics; multi-drug-resistant microorganisms; difficult-to-treat infections

(This special issue belongs to the Section Bacterial Pathogens)

Covalent Inhibitors of Pathogenic Bacterial, Protozoal, Viral, and Fungal Targets

edited by

Monika I. Konaklieva

and Balbina J. Plotkin

submission deadline 31 Dec 2025 | 1 articles | Viewed by 931 | Submission Open

Keywords: covalent inhibitors; pathogenic bacterial and viral protein targets; protozoa; fragment-based drug discovery; chemical warheads; prodrugs; STD NMR; MS; SITE (single-injection thermal extinction)

Surveillance, Prevention and Control of Sexually Transmitted Infections

edited by

Miguel A. Sánchez-Alemán

submission deadline 31 Dec 2025 | Viewed by 762 | Submission Open

Keywords: sexually transmitted infections; syphilis; herpes; papillomavirus; HIV; sexual health; epidemiology; reproductive health; prevention; diagnosis; treatment

Leishmania & Leishmaniasis

edited by

Maria Inês Fernandes Pimentel

and

Liliane de Fátima Antonio Oliveira

submission deadline 31 Dec 2025 | 1 articles | Viewed by 649 | Submission Open

Keywords: leishmaniasis; visceral leishmaniasis; cutaneous leishmaniasis; mucosal leishmaniasis; mucocutaneous leishmaniasis; human visceral leishmaniasis; canine visceral leishmaniasis

(This special issue belongs to the Section Parasitic Pathogens)

Respiratory Diseases in Swine: Epidemiology, Diagnosis and Control

edited by

Arkadiusz Dors

submission deadline 31 Dec 2025 | 1 articles | Viewed by 489 | Submission Open

Keywords: swine; respiratory diseases; diagnostics; surveillance; control strategies

Tick-Borne Encephalitis Virus: 2nd Edition

edited by

Anna Moniuszko-Malinowska

submission deadline 31 Dec 2025 | Viewed by 340 | Submission Open

Keywords: TBE; TBEV; tick; encephalitis; meningitis

Understanding Emerging and Re-Emerging Viral Infections

edited by

Jose Angel Regla Nava

submission deadline 31 Dec 2025 | Viewed by 281 | Submission Open

Keywords: diagnosis; pathogenesis; evolution; epidemiology; drugs; vaccines

(This special issue belongs to the Section Viral Pathogens)

Zoonotic Parasites in Livestock: A One Health Perspective

edited by

Helga Waap

submission deadline 31 Dec 2025 | Viewed by 280 | Submission Open

Keywords: zoonotic parasites; livestock; helminths; protozoa; arthropods; One Health

(This special issue belongs to the Section Parasitic Pathogens)

Malaria: Updates on Prevention, Diagnosis, and Treatment

edited by Temi Lampejo and

Andrew Taylor-Robinson

submission deadline 31 Dec 2025 | Viewed by 236 | Submission Open

Keywords: malaria; plasmodium; prevention; vaccines; therapeutics

(This special issue belongs to the Section Parasitic Pathogens)

Multidrug-Resistant Microorganisms’ (MDROs) Genomic Characteristics Integrated with Serum Biomarkers Measurement in the Diagnosis and Prognosis of Severe Infectious Disease as Sepsis

edited by

Silvia Spoto

and

Silvia Angeletti

submission deadline 31 Dec 2025 | Viewed by 221 | Submission Open

Keywords: procalcitonin (PCT); mid-regional-pro-adrenomedullin (MR-proADM); multidrug-resistant microorganisms (MDRO); active surveillance cultures (ACS); healthcare-associated infections (HCAIs)

Classic and Emerging Pathogens as a Cause of Healthcare-Associated Infections: Current Knowledge and Future Approaches

edited by

Alessio Facciolà

and

Antonio Laganà

submission deadline 31 Dec 2025 | Viewed by 201 | Submission Open

Keywords: antimicrobial resistance; epidemiology; healthcare-associated infections; microbiology; preventive medicine; public health

Advances in Chlamydia-Related Diseases

edited by

Katalin Burián

submission deadline 31 Dec 2025 | Viewed by 188 | Submission Open

Keywords: chlamydia; pathomechanism; host interaction; host-specific immunity; in vitro persistence model; epidemiology; treatment; vaccination

(This special issue belongs to the Section Bacterial Pathogens)

Vector-Borne Diseases and Transboundary Zoonoses: A One Health Perspective

edited by

Rafael Felipe da Costa Vieira

and

Richard de Campos Pacheco

submission deadline 31 Dec 2025 | Viewed by 172 | Submission Open

Keywords: zoonoses; one health approach; vector control; pathogen transmission; animal reservoirs; emerging infectious diseases; veterinary medicine; disease surveillance; epidemiology

Emerging Trends in Arbovirus Research: Diagnosis, Transmission, and Therapeutic Development

edited by

Paulo Ricardo da Silva Sanches

submission deadline 31 Dec 2025 | Viewed by 166 | Submission Open

Keywords: arboviruses; vector-borne diseases; viral pathogenesis; molecular diagnostics; antiviral therapies; vaccine develop-ment; vector control; infectious diseases

(This special issue belongs to the Section Viral Pathogens)

Monitoring and Management of Mosquito-Borne Pathogens in Mosquito Populations

edited by

Bethany Bolling

and Hannah Romo

submission deadline 31 Dec 2025 | Viewed by 165 | Submission Open

Keywords: mosquitoes; arboviruses; surveillance; mosquito collection; mosquito testing; integrated mosquito management; mosquito control; response plans; outbreak response

Epidemiology, Diagnosis and Clinical Management of Human Parasitic Infections—2nd Edition

edited by