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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Exploring the Therapeutic Potential of Peptides in Anti-Cancer Treatments submission deadline 30 Jun 2025 | Viewed by 156 | Submission Open
Keywords: anticancer peptides; antimicrobial peptides; cell-penetrating peptides; therapeutic peptides; cancer vaccine; theranostics; peptidomimetics; anticancer drugs; metal– peptide drugs
(This special issue belongs to the Section Medicinal Chemistry)
Contemporary Synthetic Glycoscience: A Theme Issue Dedicated to the Memory of Hans Paulsen
edited by Joachim Erich Thiem
submission deadline 30 Jun 2025 | Viewed by 155 | Submission Open
Keywords: synthesis; chemical; enzymatic; glycosylation; mono-; di-; tri-; oligosaccharides; carbohydrate-based; modified carbohydrates; glycoconjugates
(This special issue belongs to the Section Bioorganic Chemistry)
Advances in Extraction, Biological Activity of Natural Products and Their Derivatives
edited by Ernesto Santoro and
submission deadline 30 Jun 2025 | Viewed by 137 | Submission Open
Keywords: novel extraction; absolute configuration; supercritical fluid; microwave-assisted extraction; natural products
(This special issue belongs to the Section Natural Products Chemistry)
Advances in European Medicinal Chemistry submission deadline 30 Jun 2025 | Viewed by 134 | Submission Open
Keywords: medicinal chemistry; drug design; natural compounds; synthesis and analysis; structure-activity relationships; biological screening; chemical biology and biological chemistry; biomaterials; excipients
(This special issue belongs to the Section Medicinal Chemistry)
Food Polysaccharides: Structure, Properties and Application, 3rd Edition submission deadline 30 Jun 2025 | Viewed by 133 | Submission Open
Keywords: food polysaccharides; food gums; food additives; dietary fiber; structure; properties; functions; application; bioactivity
(This special issue belongs to the Section Food Chemistry)
Analytical Techniques in Environmental Chemistry, 2nd Edition
edited by
submission deadline 30 Jun 2025 | Viewed by 107 | Submission Open
Keywords: environmental analytical chemistry; contaminants; environmental impact assessment; analytical techniques; environmental pollution
(This special issue belongs to the Section Analytical Chemistry)
Wastewater Treatments Based on Adsorption, Catalysis, Biodegradation, and Beyond, 3rd Edition submission deadline 30 Jun 2025 | Viewed by 107 | Submission Open
Keywords: groundwater; wastewater; soil; environment chemistry; nanoscale zero-valent iron; photocatalysis; heavy metal; biosorbent; mechanism
(This special issue belongs to the Section Applied Chemistry)
Advances in Conversion of Biomass
edited by and Anjani Ravi Kiran Gollakota
submission deadline 30 Jun 2025 | Viewed by 106 | Submission Open
Keywords: biomass conversion; bio-based material; catalyst design; heterogeneous catalysis; enzyme catalysis
(This special issue belongs to the Section Green Chemistry)
Advances in Molecular Electric, Magnetic and Optical Properties submission deadline 30 Jun 2025 | Viewed by 83 | Submission Open
Keywords: optical properties; magnetic properties; electrical and dielectrical properties; molecular interactions; spectroscopic characterization; molecular vibrations; complex molecules
(This special issue belongs to the Section Molecular Structure)
Bioinorganic Chemistry of Metal Ions submission deadline 30 Jun 2025 | Viewed by 70 | Submission Open
Keywords: metalloproteins; metalloenzymes; metal clusters; metal– organic frameworks; oxygen-evolving Mn4CaO5 cluster; drug targets; metal-associated pathologies
(This special issue belongs to the Section Inorganic Chemistry)
The Therapeutic Potential of Natural Polysaccharides or Polysaccharide Conjugates
edited by
submission deadline 30 Jun 2025 | Viewed by 68 | Submission Open
Keywords: antioxidants in plants; oxidative damage and health hazards; scavenging effects of free radicals; enhancement in antioxidant enzyme activities; intestinal flora metabolism and antioxidant effects
(This special issue belongs to the Section Natural Products Chemistry)
Chemistry of the Manganese(III) Ion
edited by
submission deadline 30 Jun 2025 | Viewed by 63 | Submission Open
Keywords: manganese; Mn(III); Mn environmental chemistry; dissolved Mn(III); Mn(III) analysis; Mn(III) speciation; Mn geochemistry; Mn geobiology
Advancing Drug Discovery for Neglected Tropical Diseases (NTDs) submission deadline 1 Jul 2025 | 1 articles | Viewed by 965 | Submission Open
Keywords: antimicrobial agents; structure- and ligand-based drug design; poverty-related diseases; challenges and opportunities; global health
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Synthesis of Antiviral Compounds
edited by and Francesco Saccoliti
submission deadline 1 Jul 2025 | Viewed by 158 | Submission Open
Keywords: antiviral; drug design; medicinal chemistry; antiviral small molecules; synthesis; synthetic drugs; antimicrobial
(This special issue belongs to the Section Organic Chemistry)
Biomass-Derived Nanomaterials: Sustainable Production and Application
edited by
submission deadline 3 Jul 2025 | 3 articles | Viewed by 11180 | Submission Open
Keywords: carbon nanotubes; nanocellulose; nanostructures; lignin nanoparticles; top-down approaches; surface functionalization; applications; cytoxicity; toxicology; life-cycle assessment
(This special issue belongs to the Section Nanochemistry)
Natural Products with Antiviral, Anti-inflammatory and Immunomodulatory Activities
edited by
submission deadline 7 Jul 2025 | 4 articles | Viewed by 10508 | Submission Open
Keywords: antiviral; anti-inflammatory and immunomodulatory activities; rational drug design; structural modification; biotransformation; chemical biology; mechanism
(This special issue belongs to the Section Natural Products Chemistry)
Chemical Constituents and Biological Activities of Natural Sources submission deadline 15 Jul 2025 | 3 articles | Viewed by 2388 | Submission Open
Keywords: natural compounds; biological activities; isolation; identification and structural elucidation; pharmacological evaluation
(This special issue belongs to the Section Natural Products Chemistry)
Deep Eutectic Solvents for the Extraction of Bioactive Compounds from Natural Sources
edited by Kristina Radošević and
submission deadline 15 Jul 2025 | 1 articles | Viewed by 958 | Submission Open
Keywords: bioactive compounds; natural sources; biological activity; deep eutectic solvents; green extraction; sustainable solvents; natural product valorization
(This special issue belongs to the Section Cross-Field Chemistry)
ECSOC-28 submission deadline 15 Jul 2025 | Viewed by 284 | Submission Open
Keywords: organic synthesis; synthesis of natural products; computational chemistry
Synthesis, Characterization and Biological Evaluation of Metal Complexes submission deadline 15 Jul 2025 | Viewed by 112 | Submission Open
Keywords: metal complexes; biological activity; anticancer; bioinorganic; anti-inflammatory; antimicrobial; Alzheimer's disease
(This special issue belongs to the Section Cross-Field Chemistry)
Nutritional Properties and Sensory Analysis of Food submission deadline 15 Jul 2025 | Viewed by 8 | Submission Open
Keywords: sensory evaluation; sensory methods; nutritional value of food; functional ingredients; food safety; texture of food; antioxidant activity; chemical composition
(This special issue belongs to the Section Food Chemistry)
Lipids and Surfactants in Delivery Systems
edited by Agnieszka Lewińska and Marta Domżał-Kędzia
submission deadline 22 Jul 2025 | 2 articles | Viewed by 2046 | Submission Open
Keywords: delivery systems; controlled-release systems; targeted delivery systems; preparation and characterization; surfactant– lipid interactions; lipid and surfactant nanocarriers; bioavailability enhancement; nanotechnology
(This special issue belongs to the Section Nanochemistry)
Unlocking the Formulation Potential of Cyclodextrins and Their Derivatives—2nd Edition
edited by , and Paraskevi Papakyriakopoulou
submission deadline 25 Jul 2025 | 4 articles | Viewed by 5126 | Submission Open
Keywords: cyclodextrins; cyclodextrin-drug interactions; formulations; drug loading; release kinetics; routes of administration; in vitro-in vivo evaluation; PK/PD studies
(This special issue belongs to the Section Medicinal Chemistry)
New Perspective on Polysaccharides: From Isolation to Biological Evaluation
edited by and Zhiqiang Xiong
submission deadline 30 Jul 2025 | Viewed by 123 | Submission Open
Keywords: extraction methodology; separation technology; bioactivities; biological evaluation; polysaccharides
(This special issue belongs to the Section Natural Products Chemistry)
New Insights into Electrochemical Energy Storage and Conversion: Aqueous Rechargeable Batteries
edited by and Ruizheng Zhao
submission deadline 30 Jul 2025 | 1 articles | Viewed by 120 | Submission Open
Keywords: aqueous batteries; electrochemical reactions; electrode materials; electrolyte; regulation
(This special issue belongs to the Section Electrochemistry)
π-Conjugated Functional Molecules & Polymers submission deadline 31 Jul 2025 | 15 articles | Viewed by 23501 | Submission Open
Keywords: π -conjugated functional materials; conjugated porous polymers; covalent organic framework; metal– organic framework; synthetic methodology; aggregation-induced organic emissions; nonlinear optics; light-emitting diodes; organic field effect transistors; organic photovoltaic cells; photocatalysis
(This special issue belongs to the Section Materials Chemistry)
Featured Review Papers in Bioorganic Chemistry submission deadline 31 Jul 2025 | 4 articles | Viewed by 19502 | Submission Open
Keywords: bioorganic chemistry; enzyme inhibitors; biocatalysis; biosynthesis; immunochemical techniques; membrane chemistry; peptides chemistry
(This special issue belongs to the Section Bioorganic Chemistry)
Tea Processing and Flavor Research submission deadline 31 Jul 2025 | 4 articles | Viewed by 12967 | Submission Open
Keywords: processing theory and technology; six types of tea; flavor chemistry; flavor analysis; aroma and flavor perception
(This special issue belongs to the Section Flavours and Fragrances)
Novel Two-Dimensional Energy-Environmental Materials
edited by , Ning Wang and Xiangkai Kong
submission deadline 31 Jul 2025 | 10 articles | Viewed by 10893 | Submission Open
Keywords: two-dimensional energy materials and heterostructures; solar cells and photodetectors; thermoelectric materials; photocatalysis; electrocatalysis; energy storage materials; environmentally friendly materials; environmental pollution remediation; synthesis and preparation methods
(This special issue belongs to the Section Materials Chemistry)
Applied Chemistry in Europe
edited by and Gianluca D'Abrosca
submission deadline 31 Jul 2025 | 4 articles | Viewed by 10106 | Submission Open
Keywords: industrial applications; nano-materials; environmental chemistry; chemical synthesis; green chemistry; theoretical chemistry; analytical methods
(This special issue belongs to the Section Applied Chemistry)
Study on Synthesis and Photochemistry of Dyes
edited by Liang Han
submission deadline 31 Jul 2025 | 6 articles | Viewed by 8765 | Submission Open
Keywords: synthesis of dyes; photochemistry of dyes; organic dyes; functional organic dyes; photo-inducing materials; organic photoelectric materials
(This special issue belongs to the Section Photochemistry)
Organometallic Compounds: Design, Synthesis and Application
edited by
submission deadline 31 Jul 2025 | 9 articles | Viewed by 8587 | Submission Open
Keywords: organometallic compounds; design and synthesis; transition metal complexes; catalysis; metal coordination; catalytic applications; mechanisms; organic– inorganic hybrid compounds
(This special issue belongs to the Section Organometallic Chemistry)
Current Development of Asymmetric Catalysis and Synthesis
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 8157 | Submission Open
Keywords: asymmetric synthesis; asymmetric catalysis; transition metal-catalyzed asymmetric catalysis and synthesis; organocatalyzed asymmetric catalysis and synthesis; enzyme-catalyzed catalysis and synthesis; kinetic resolution; theoretical investigations into asymmetric catalysis and synthesis
(This special issue belongs to the Section Organic Chemistry)
Research and Application of Plant Sourced Polysaccharides—2nd Edition
edited by and
submission deadline 31 Jul 2025 | 8 articles | Viewed by 8135 | Submission Open
Keywords: polysaccharide; characterization; structure; physiochemical properties; functional activity
(This special issue belongs to the Section Natural Products Chemistry)
Design, Synthesis and Applications of Bioactive Compounds submission deadline 31 Jul 2025 | 5 articles | Viewed by 7961 | Submission Open
Keywords: bioactive compounds; molecular design; synthetic methods; natural products and modification of natural products; in silico drug design; structure– activity relationship; drug discovery; biomedical applications
(This special issue belongs to the Section Medicinal Chemistry)
10th Anniversary of Green Chemistry Section submission deadline 31 Jul 2025 | 11 articles | Viewed by 7749 | Submission Open
Keywords: green catalysts; green extraction and processing; chemistry based on natural products; bio-based solvents with sub- and super-critical fluids; microwave and ultrasound; organic reaction in green solvents; bioconversion of biomass and sustainable biomaterials; creating fine chemicals and polymers from renewable resources; green nanotechnology; green analytical chemistry; green degradation process
(This special issue belongs to the Section Green Chemistry)
Analytical Methods for Food and Environmental Pollutants: Current and Future Perspectives submission deadline 31 Jul 2025 | 6 articles | Viewed by 6638 | Submission Open
Keywords: emerging pollutants; food samples; environmental samples; sampling; sample preparation; analytical instrumentation; chemometric tools
(This special issue belongs to the Section Analytical Chemistry)
Analyses and Applications of Phenolic Compounds in Food—2nd Edition submission deadline 31 Jul 2025 | 5 articles | Viewed by 5845 | Submission Open
Keywords: phenolics; extraction; identification; applications in food matrix
(This special issue belongs to the Section Food Chemistry)
Chemistry of Nucleosides and Nucleotides and Their Analogues submission deadline 31 Jul 2025 | 2 articles | Viewed by 5704 | Submission Open
Keywords: nucleosides; nucleotides; and nucleic acids; modified nucleosides and nucleotides; nucleoside and nucleotide analogues; antimetabolites; oligonucleotides; organic synthesis; bioorganic chemistry; medicinal chemistry
(This special issue belongs to the Section Organic Chemistry)
Surfactants at the Soft Interfacial Layer
edited by
submission deadline 31 Jul 2025 | 4 articles | Viewed by 5681 | Submission Open
Keywords: surfactant; water surface; evaporation; emulsion; foaming
(This special issue belongs to the Section Physical Chemistry)
Natural Products with Pharmaceutical Activities
edited by and
submission deadline 31 Jul 2025 | 8 articles | Viewed by 5546 | Submission Open
Keywords: bioactive compounds; drug discovery; natural products chemistry; pharmacological evaluation; structure– activity relationship
(This special issue belongs to the Section Natural Products Chemistry)
Exclusive Papers of the Editorial Board Members and Topical Advisory Panel Members of Molecules in the Section “Applied Chemistry”
edited by and Eleonora-Mihaela Ungureanu
submission deadline 31 Jul 2025 | 4 articles | Viewed by 5083 | Submission Open
Keywords: applied chemistry; new molecules/materials; analytical methods and techniques; electrochemistry and catalysis; green chemistry; theoretical chemistry
(This special issue belongs to the Section Applied Chemistry)
Applications of Fluorescent Sensors in Food and Environment submission deadline 31 Jul 2025 | 3 articles | Viewed by 4975 | Submission Open
Keywords: environmental pollutants; food quality; heavy metals and anions sensing; fluorescent quantum dots; luminescent metal organic frameworks (LMOFs); fluorescent polymers; fluorescent small molecules and supramolecular sensors; vapoluminescent materials
(This special issue belongs to the Section Materials Chemistry)
Recent Advances in Functional Composite Materials
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 4892 | Submission Open
Keywords: functional composites; material innovation; enhanced properties; nanotechnology; smart materials
(This special issue belongs to the Section Materials Chemistry)
Bioactive Compounds: Applications and Benefits for Human Health
edited by Sara Baldelli, and
submission deadline 31 Jul 2025 | 4 articles | Viewed by 4697 | Submission Open
Keywords: bioactive compounds; polyphenols; terpenoids; alkaloids; glucosinolates; antioxidant; anti-inflammatory; cardiovascular diseases; bacterial and viral infections; microbiota; neurodegenerative diseases; cancer; sarcopenia; identification; purification; extraction; pre-clinical; clinical
(This special issue belongs to the Section Natural Products Chemistry)
Boron Chemistry and Applications
edited by Liang Xu and Yu Wei
submission deadline 31 Jul 2025 | 4 articles | Viewed by 4654 | Submission Open
Keywords: boron-based materials; boron-based catalysts; boronyl synthons; boron neutron capture therapy
(This special issue belongs to the Section Organic Chemistry)
Research Progress of Fluorescent Probes
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 4601 | Submission Open
Keywords: one-photon fluorescent probes; two-photon fluorescent probes; multi-photon fluorescent probes; upconverting fluorescent probes; AIE fluorescent probes
(This special issue belongs to the Section Photochemistry)
Design, Synthesis and Applications of Novel Transition Metal Catalysts
edited by Hui Jiang and Junfang Gong
submission deadline 31 Jul 2025 | 5 articles | Viewed by 4496 | Submission Open
Keywords: pincer catalysts; transition metal catalysts; organic synthetic methodologies; photocatalysis; electrocatalysis; polymerization; fine chemistry
(This special issue belongs to the Section Applied Chemistry)
Bioactive Compounds from Foods for Health Benefits submission deadline 31 Jul 2025 | 3 articles | Viewed by 4477 | Submission Open
Keywords: polyphenolic compounds; bioactive compound; natural products; food safety; phytochemicals; carotenoids; LC-MS/MS techniques; HPLC-DAD-MS; fruits; vegetables; and mushrooms; antioxidant compounds; functional food; prebiotics; health beneficial
(This special issue belongs to the Section Natural Products Chemistry)
The Medicinal Value of Natural Products submission deadline 31 Jul 2025 | 1 articles | Viewed by 4391 | Submission Open
Keywords: natural products; antioxidants; antimicrobial properties; drug discovery; therapeutics; anti-neoplastic; pharmacognosy
(This special issue belongs to the Section Natural Products Chemistry)
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