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Molecules, Volume 30, Issue 13

July-1 2025 - 224 articles

Cover Story: Natural colorants, valued for their sustainable origins, provide a promising alternative for various applications. Recent evidence emphasizes their notable properties, resilience, and durability—traits that ancient dyes, produced through eco-friendly methods, have demonstrated successfully. Such findings highlight the potential of sustainable solutions in our field. In our study, we crafted three medieval temperas using gum arabic, parchment glue, and casein glue, each specifically formulated to preserve the purple hues from Chrozophora tinctoria extracts. In our work, we employ a comprehensive multi-analytical approach. The results reveal the unique characteristics of Chrozophora tinctoria, clearly setting it apart from orcein purples and illustrating each dye's distinctiveness. View this paper
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Articles (224)

  • Brief Report
  • Open Access
1 Citations
1,022 Views
11 Pages

Lipophenols, combining phenolic and lipid characteristics in an amphiphilic molecule, offer unique bioactive properties with therapeutic potential, including anti-inflammatory and anti-oxidant effects. Thus, palmitoyl-epigallocatechin gallate (PEGCG)...

  • Article
  • Open Access
2 Citations
1,343 Views
25 Pages

Accurate determination of carbon core-electron binding energies (C1s CEBEs) is crucial for X-ray photoelectron spectroscopy (XPS) assignments and predictive computational modeling. This study evaluates density functional theory (DFT)-based methods fo...

  • Review
  • Open Access
6 Citations
4,423 Views
27 Pages

Increasing Life Expectancy with Plant Polyphenols: Lessons from the Mediterranean and Japanese Diets

  • Marco Fiore,
  • Anton B. Tonchev,
  • Ruzha Z. Pancheva,
  • Tetsumori Yamashima,
  • Sabrina Venditti,
  • Giampiero Ferraguti and
  • Sergio Terracina

Plant polyphenols have emerged as potent bioactive molecules that can modulate key cellular pathways associated with aging and chronic disorders. The Mediterranean diet and the traditional Japanese style of life are rich in polyphenol-containing food...

  • Article
  • Open Access
1,182 Views
21 Pages

Revealing Serotonin Derivatives in Safflower Seed Meal as Potential Anti-Ulcerative Colitis Drugs: In Vitro and Computational Evidence

  • Liang Zhang,
  • Md Hasan Ali,
  • Chao Jiang,
  • Furong Fan,
  • Furong Zhu,
  • Yating Lu,
  • Mengwei Jia,
  • Haipeng Yin,
  • Jianwang Wei and
  • Dongsen Wu
  • + 2 authors

This study evaluated the in vitro anti-inflammatory activity of serotonin derivatives from safflower seed powder and elucidated their mechanism against ulcerative colitis using network pharmacology. Compounds were extracted and purified via silica ge...

  • Article
  • Open Access
2 Citations
1,631 Views
46 Pages

Rapid economic growth has led to an increase in the use of multilayer plastic packaging, which involves complex polymer compositions and hinders recycling. This study investigated the catalytic pyrolysis of plastic packaging waste in a 3000 cm3 semib...

  • Article
  • Open Access
741 Views
15 Pages

At a time of climate change, farmers face difficulties in providing food for a growing population. This results in the overuse of water and fertilisers. The aim of the research was to test the possibility of introducing waste sheep wool fibres into a...

  • Review
  • Open Access
5 Citations
4,176 Views
47 Pages

Oxysterol-Induced Inflammation in Human Diseases: Strategies for Treatment with Natural Compounds and Synthetic Molecules

  • Fatiha Brahmi,
  • John J. Mackrill,
  • Imen Ghzaiel,
  • Leila Rezig,
  • Rym Benkhalifa,
  • Amira Zarrouk,
  • Pierre Jouanny,
  • Anne Vejux and
  • Gérard Lizard

Oxysterols can be derived from the diet, physiologically produced via specific enzymes, or are generated by autoxidation. These molecules have physiological properties and can also adversely affect vital organs. Indeed, some of them have pro-oxidant...

  • Article
  • Open Access
2 Citations
1,658 Views
25 Pages

Phytochemical Screening and Biological Activities of Lippia multiflora Moldenke

  • Dorcas Tlhapi,
  • Ntsoaki Malebo,
  • Idah Tichaidza Manduna,
  • Monizi Mawunu and
  • Ramakwala Christinah Chokwe

Lippia multiflora Moldenke is widely used in Angola, on the African continent, and beyond for the treatment of many health conditions such as hypertension, enteritis, colds, gastrointestinal disturbances, stomachaches, jaundice, coughs, fevers, nause...

  • Article
  • Open Access
1,126 Views
21 Pages

Periodontitis is an inflammatory disease that affects the periodontal supporting tissues. Its cardinal clinical manifestations encompass gingival inflammation, periodontal pocket formation, and alveolar bone resorption. Urolithin A (UA), a gut microb...

  • Article
  • Open Access
1 Citations
1,146 Views
16 Pages

Synthesis of Novel Tetra-Substituted Pyrazole Derivatives Using Microwave Irradiation and Their Anti-Leukemic Activity Against Jurkat Cells

  • Felipe P. Machado,
  • Maria Clara Campos,
  • Juliana Echevarria-Lima,
  • Diego P. Sangi,
  • Carlos Serpa,
  • Otávio Augusto Chaves and
  • Aurea Echevarria

Three previously synthesized ketene dithioacetals were used as intermediates to obtain four nucleophiles to synthesize ten tetra-substituted pyrazoles (11–20). This was achieved through microwave irradiation in ethanol as the solvent, yielding...

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Molecules - ISSN 1420-3049