Discovery of New Natural Derived Compounds and Mechanisms for Chronic Diseases Therapy
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 196
Special Issue Editors
2. Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain
Interests: chronic diseases; neurodegenerative dysfunctions; biomaterials; supramolecular chemistry; drug delivery systems; medicinal chemistry; natural products
Special Issues, Collections and Topics in MDPI journals
Interests: cancer therapies; natural products; biomolecular recognition; coordination chemistry; targeted drug delivery
Special Issue Information
Dear Colleagues,
Promising and novel cancer therapies have been investigated in natural compounds, their structural analogs, and semisynthetic derivatives, revealing a remarkable diversity in their chemical properties. Moreover, the modular structure of these products with natural frameworks enhances their potential for greater safety and effectiveness.
Among the many natural molecular systems are flavonoids, porphyrins, sugars, and mimetic peptides, as well as their metallo-derivatives, which have provided platforms for the specific recognition and stabilization of biomolecules. This has opened new possibilities in biomedicine to avoid unwanted effects, pharmacological resistance, and to enhance the bioavailability of promising therapeutic agents. Coordination chemistry and self-assembly have been among the most versatile synthetic tools for developing new molecular and supramolecular architectures that target elusive biological targets associated with degenerative or chronic disorders. The ability of these systems to organize themselves in a structured and functional way is crucial for their specific interactions with biomolecules, enabling the development of innovative devices such as biomolecular sensors, controlled drug delivery systems, and platforms for personalized therapies.
Prof. Dr. Eduardo Sobarzo-Sánchez
Guest Editor
Dr. Marianela Saldías
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- cancer therapies
- natural products
- biomolecular recognition
- coordination chemistry
- targeted drug delivery
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