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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Phenolic Based Complexes
edited by
submission deadline 30 Apr 2026 | 6 articles | Viewed by 10904 | Submission Open
Keywords: phenolic compounds; complexes; structure; properties; applications; analysis
Food Bioactive Components in Functional Foods and Nutraceuticals submission deadline 30 Apr 2026 | 5 articles | Viewed by 9370 | Submission Open
Keywords: functional foods; nutraceuticals; bioactive compounds; health benefits; disease prevention; bioavailability
(This special issue belongs to the Section Food Chemistry)
Exploring Analytical Techniques in Pharmaceutical and Biomedical Analysis
edited by and
submission deadline 30 Apr 2026 | 6 articles | Viewed by 9242 | Submission Open
Keywords: pharmaceutical analysis; biomedical analysis; chromatographic analysis; spectroscopic analysis; mass spectrometry analysis; capillary electrophoresis; electrochemical analysis
(This special issue belongs to the Section Medicinal Chemistry)
Therapeutic Agents for Neurodegenerative Disorders—2nd Edition
edited by
submission deadline 30 Apr 2026 | 4 articles | Viewed by 9177 | Submission Open
Keywords: beta amyloid; tau; alpha-synuclein; huntingtin; autophagy; neuromodulators; neurotrophins; natural compounds; neuroinflammation; vascular dysfunction; neuronal death; drug development; therapeutic biomarkers; blood– brain barrier; small-molecule therapeutics; theranostics
(This special issue belongs to the Section Medicinal Chemistry)
Natural Products: Extraction, Analysis and Biological Activities
edited by and Łukasz Paprotny
submission deadline 30 Apr 2026 | 5 articles | Viewed by 8055 | Submission Open
Keywords: plant products; secondary metabolites; extraction; analysis; quality of natural products; biological activity; health-promoting properties; agricultural waste
(This special issue belongs to the Section Natural Products Chemistry)
Materials for Emerging Electrochemical Devices—2nd Edition submission deadline 30 Apr 2026 | 4 articles | Viewed by 7908 | Submission Open
Keywords: solid-state devices; batteries; electrochromic devices; smart windows; electrochemical devices
(This special issue belongs to the Section Materials Chemistry)
Phytochemical Investigation of Bioactive Constituents from Medicinal Plants submission deadline 30 Apr 2026 | 4 articles | Viewed by 6682 | Submission Open
Keywords: primary metabolites; secondary metabolites; biological activity; phytochemistry; natural products; HPLC-analysis; spectral analysis; medicinal plants
(This special issue belongs to the Section Natural Products Chemistry)
Volatile Natural Products: Extraction, Characterization and Application
edited by
submission deadline 30 Apr 2026 | 5 articles | Viewed by 6409 | Submission Open
Keywords: volatile components; aroma; essential oil; extraction methods; gas chromatography; gas chromatography– mass spectrometry; natural products
(This special issue belongs to the Section Natural Products Chemistry)
The Anticancer Drugs: A New Perspective
edited by and
submission deadline 30 Apr 2026 | 3 articles | Viewed by 6143 | Submission Open
Keywords: anticancer therapy; targeted therapy; drug design; drug discovery; drug synthesis; nanotechnology
(This special issue belongs to the Section Medicinal Chemistry)
Synthesis and Biological Evaluation of Coordination Compounds
edited by , Francisco Ferreira De Sousa and
submission deadline 30 Apr 2026 | 4 articles | Viewed by 5683 | Submission Open
Keywords: synthetic chemistry; coordination chemistry; biological activity; complexes; drug design; molecular targeting; metal– ligand interactions
(This special issue belongs to the Section Inorganic Chemistry)
Green and Environmentally Friendly Visible-Light- and Transition Metal-Catalyzed Synthesis
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 5233 | Submission Open
Keywords: green synthesis; sustainable chemistry; transition metal catalysis; light induced transformations; photoredox catalysis; organic synthesis
(This special issue belongs to the Section Organic Chemistry)
Exploring Bioactive Compounds in Foods and Nutrients for Human Health submission deadline 30 Apr 2026 | 3 articles | Viewed by 5179 | Submission Open
Keywords: chronic non-communicable diseases; bioactive compounds; nutrients; human health
Advances in Computational Spectroscopy, 2nd Edition
edited by and Małgorzata Biczysko
submission deadline 30 Apr 2026 | 6 articles | Viewed by 5040 | Submission Open
Keywords: spectroscopy; computational spectroscopy in inorganic chemistry; computational spectroscopy in bioinorganic chemistry; computational spectroscopy in biological systems; molecular and supramolecular structure; crystal structure; molecular modelling; time-independent and time-dependent approaches; molecular dynamics; density functional theory (DFT); time-dependent DFT (TD-DFT); coupled cluster (CC) approaches and composite schemes; bottom-up and top-down semi-experimental approaches
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Recent Advances in Porous Materials, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 5 articles | Viewed by 4896 | Submission Open
Keywords: porous carbon; adsorption; catalysis; supercapacitor; biomass; energy storage; zeolite; fuel cell; molecular sieves; metal– organic frameworks; porous metal oxide; mesoporous silicon; macroporous resin; aerogel; separation; porous composites; covalent organic frameworks
(This special issue belongs to the Section Materials Chemistry)
Chemical Analysis of Pollutant in the Environment submission deadline 30 Apr 2026 | 5 articles | Viewed by 4744 | Submission Open
Keywords: inorganic and organic pollutants; persistent organic pollutants; heavy metals; nano- and microplastics; chemical methods; instrumental methods; validation
(This special issue belongs to the Section Green Chemistry)
Functional Materials for Chemical Sensing in Molecules
edited by , and Ming Hou
submission deadline 30 Apr 2026 | 2 articles | Viewed by 4565 | Submission Open
Keywords: functional materials; sensing materials; nanomaterials; composites; design and synthesis; chemical sensing; gas sensors; humidity sensors; biosensors
(This special issue belongs to the Section Materials Chemistry)
Innovative Approaches to Sustainable Wastewater Treatment—Recent Developments in Hazardous Pollutants Removal submission deadline 30 Apr 2026 | 6 articles | Viewed by 4379 | Submission Open
Keywords: wastewater treatment; industrial wastewater; physical methods; chemical methods; biological methods; emerging micropollution; dyes; heavy metals; removal; (bio)sorbent; ion exchange resin
(This special issue belongs to the Section Green Chemistry)
Recent Advances in Transition Metal Catalysis, 2nd Edition
edited by Dingyi Wang
submission deadline 30 Apr 2026 | 3 articles | Viewed by 4264 | Submission Open
Keywords: transition metal catalysis; photocatalysis; electrosynthesis; organic synthesis; asymmetric synthesis; C-H functionalization; C-C functionalization; C-X functionalization
(This special issue belongs to the Section Organic Chemistry)
Advance in Radiochemistry, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 4 articles | Viewed by 4074 | Submission Open
Keywords: radiochemistry; radionuclide (radioisotopes); radiolabeling; radiopharmaceutical (radiotracer); nuclear medicine; theranostics (diagnostics and therapeutics); molecular imaging
(This special issue belongs to the Section Medicinal Chemistry)
Advances and Opportunities of Natural Products in Drug Discovery submission deadline 30 Apr 2026 | 5 articles | Viewed by 3846 | Submission Open
Keywords: natural products; drug discovery; pharmacological activity; biological activity; new compounds
(This special issue belongs to the Section Natural Products Chemistry)
Advanced Functional Membrane Materials: Fabrication and Applications
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 3772 | Submission Open
Keywords: functional membrane material; nanochemistry; polymeric synthesis; molecular design; synthesis method; material processing; catalysis and separation
(This special issue belongs to the Section Applied Chemistry)
Catalytic Materials for Energy and Environment: Preparation, Properties and Applications
edited by and Yanfei Xu
submission deadline 30 Apr 2026 | 2 articles | Viewed by 3657 | Submission Open
Keywords: biomass conversion; CO2 hydrogenation; plastic degradation; alkane dehydrogenation; syngas conversion; methane reforming; catalysts for energy and environment; catalytic mechanism
(This special issue belongs to the Section Materials Chemistry)
Bee Product Chemistry: Identification and Characterization of Natural Compounds, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 4 articles | Viewed by 3443 | Submission Open
Keywords: honey; wax; bee pollen; venom; propolis; royal jelly; bee larvae
(This special issue belongs to the Section Natural Products Chemistry)
Exploring the Therapeutic Potential of Peptides in Anti-Cancer Treatments submission deadline 30 Apr 2026 | 2 articles | Viewed by 2918 | Submission Open
Keywords: anticancer peptides; antimicrobial peptides; cell-penetrating peptides; therapeutic peptides; cancer vaccine; theranostics; peptidomimetics; anticancer drugs; metal– peptide drugs
(This special issue belongs to the Section Medicinal Chemistry)
Plant Metabolites: Isolation, Phytochemistry, and Biological Activities
edited by , Karolina Grabowska and
submission deadline 30 Apr 2026 | 3 articles | Viewed by 2908 | Submission Open
Keywords: isolation; plant metabolites; plant extracts; medicinal plants; biological activity assessment
(This special issue belongs to the Section Natural Products Chemistry)
Back to Nature: Pharmacological Activities of Phytochemicals Isolated from Medicinal Plants
edited by and Ludmila Yarmolinsky
submission deadline 30 Apr 2026 | 2 articles | Viewed by 2813 | Submission Open
Keywords: medicinal plant; pharmacological activity; phytochemical; disease; drug; therapeutic; polyphenol; terpene; carotenoid; saponin; alkaloid; thiophene; sugar; fatty oil; resin; phytosterol; protein; peptide; anti-inflammatory; antidiabetic; neuroprotective; anticancer; antioxidative; antimicrobial; antiviral; antifungal
(This special issue belongs to the Section Natural Products Chemistry)
Chemical Biology in Asia—Second Edition
edited by and
submission deadline 30 Apr 2026 | 1 articles | Viewed by 2709 | Submission Open
Keywords: chemical biology; drug discovery; bioorganic chemistry; enzymology; synthetic biology; analytical tools
(This special issue belongs to the Section Chemical Biology)
Supramolecular Host/Guest Compounds and Their Prospects for Multifunctional Materials
edited by Angela Danil De Namor and Nawal Al Hakawati
submission deadline 30 Apr 2026 | 1 articles | Viewed by 2385 | Submission Open
Keywords: supramolecular chemistry; host-guest chemistry; macrocycles and cages; self-assembly; supramolecular materials
(This special issue belongs to the Section Macromolecular Chemistry)
A Themed Issue in Honor of the 20th Anniversary of the Mexican Academy of Organic Chemistry (AMQO)
edited by Ivan Romero-Estudillo, , Alicia Boto and
submission deadline 30 Apr 2026 | 3 articles | Viewed by 2364 | Submission Open
Keywords: organic chemistry; chemistry process; chemistry; chemical science; science in Mexico
(This special issue belongs to the Section Organic Chemistry)
Bioactive Properties and Chemical Composition of Wild Edible Species, 2nd Edition
edited by Spyridon Petropoulos
submission deadline 30 Apr 2026 | 2 articles | Viewed by 2093 | Submission Open
Keywords: wild edible species; bioactive properties; polyphenols; antioxidant activity; antimicrobial properties; carotenoids; vitamins
(This special issue belongs to the Section Natural Products Chemistry)
Biopolymers for Drug Delivery Systems
edited by and Petra Arany
submission deadline 30 Apr 2026 | 3 articles | Viewed by 1944 | Submission Open
Keywords: drug delivery systems; biopolymers; personalized medication; nanoparticle; hydrogel; 3D printing
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Electrochemical Reactions, Mechanisms and Sensing Applications submission deadline 30 Apr 2026 | 1 articles | Viewed by 1927 | Submission Open
Keywords: electrochemical reactions; reaction mechanisms; electrocatalysis; electrochemical sensing; organic and organometallic compounds; analytical electrochemistry
(This special issue belongs to the Section Electrochemistry)
Natural Products Chemistry in Asia
edited by and
submission deadline 30 Apr 2026 | 3 articles | Viewed by 1895 | Submission Open
Keywords: isolation protocol; structure elucidation; synthesis; biosynthesis; bioactivity; chemical ecology
(This special issue belongs to the Section Natural Products Chemistry)
Re-Valorization of Waste and Food Co-Products submission deadline 30 Apr 2026 | 1 articles | Viewed by 1890 | Submission Open
Keywords: by-products; valorization; reutilization; zero waste; application of functional ingredients; circular economy
(This special issue belongs to the Section Green Chemistry)
Synthesis, Bioactivity and Structure–Activity Relationship of Natural Products and Their Derivatives
edited by Jelena R. Đorović Jovanović and
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1728 | Submission Open
Keywords: natural products; structure– activity relationship (SAR); semi-synthetic derivatives; bioactivity; drug discovery; therapeutic potential; pharmaceutical innovation; bioactive compound modification
(This special issue belongs to the Section Natural Products Chemistry)
Design and Synthesis of Novel Adsorbents for Pollutant Removal, 2nd Edition
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1714 | Submission Open
Keywords: wastewater treatment; adsorbents; sustainable materials; adsorption mechanisms; surface chemistry; selective adsorption
(This special issue belongs to the Section Physical Chemistry)
Design, Synthesis and Biological Evaluation of Medicinal Potential Compounds—2nd Edition submission deadline 30 Apr 2026 | 3 articles | Viewed by 1713 | Submission Open
Keywords: bioactive compounds; design; synthesis; biological evaluation; in silico evaluation; in vitro evaluation; in vivo evaluation
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Extraction Techniques for Elemental Analysis
edited by Ricardo Cassella
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1674 | Submission Open
Keywords: sample preparation; microextraction; liquid— liquid extraction; solid-phase extraction; elemental analysis
(This special issue belongs to the Section Analytical Chemistry)
Chemical Analysis of Organic Contaminants and Microplastics submission deadline 30 Apr 2026 | 1 articles | Viewed by 1455 | Submission Open
Keywords: environment and food; instrumentation; plastic– organic contaminants interactions; life-cycle assessment; (eco)toxicity
(This special issue belongs to the Section Analytical Chemistry)
Exploring Phytochemicals: Their Structure, Biological Activities and Health-Promoting Effects
edited by and Samireh Jorfi
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1359 | Submission Open
Keywords: phytochemicals; medicinal/culinary plants; bioactive properties; health benefits
(This special issue belongs to the Section Natural Products Chemistry)
Ligand-Based Design and Optimization of Antibacterial Agents: From Structure to Activity submission deadline 30 Apr 2026 | 1 articles | Viewed by 1343 | Submission Open
Keywords: ligand-based drug design (LBDD); antibacterial agents; quantitative structure– activity relationship (QSAR); pharmacophore modeling; virtual screening; cheminformatics; molecular optimization
(This special issue belongs to the Section Medicinal Chemistry)
Innovative Strategies for the Extraction, Processing, and Encapsulation of Food Bioactive Compounds
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1235 | Submission Open
Keywords: bioactive compounds; extraction techniques; green and sustainable approaches; processing technologies; encapsulation systems; stability and bioavailability; food chemistry and nanotechnology; functional food applications
(This special issue belongs to the Section Food Chemistry)
Plant-Based Food Science: Chemical Composition and Biological Activity—2nd Edition
edited by and Barbara Soldo
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1190 | Submission Open
Keywords: plants; extraction; chemical composition; biologically active compounds; antioxidation; antitumor activity; microbiological activity
(This special issue belongs to the Section Natural Products Chemistry)
Functional Nanomaterials in Green Chemistry: Catalysis and Environmental Remediation
edited by , and Ingridy Dayane dos Santos Silva
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1082 | Submission Open
Keywords: functional nanomaterials; green chemistry; nanocatalysis; environmental catalysts; environmental remediation; biomass conversion; heterogeneous catalysis
(This special issue belongs to the Section Green Chemistry)
Pharmacological Bioassays of Secondary Metabolites of Medicinal Plants submission deadline 30 Apr 2026 | 1 articles | Viewed by 1058 | Submission Open
Keywords: pharmacology of medicinal plants; pharmacology of natural products; medicinal plants; mechanisms of action (cardiovascular; nervous system; digestive; etc.); active principles in diseases (Parkinson's; cancer; ulcers; etc.); isolation and bioassays of medicinal plant extracts
(This special issue belongs to the Section Natural Products Chemistry)
Photoelectrochemical Properties of Nanostructured Thin Films
edited by , Zheng Xie and Xiaofeng Zhao
submission deadline 30 Apr 2026 | 1 articles | Viewed by 885 | Submission Open
Keywords: photoelectrochemical water splitting; CO2 reduction; photocatalysis; surface engineering; co-catalyst integration; sustainable energy conversion; thin-film heterojunctions; advanced functional nanomaterials
(This special issue belongs to the Section Photochemistry)
Novel Food Processing Technologies and Their Effects on Bioactive Components in Foods
edited by and Xiao Wang
submission deadline 30 Apr 2026 | 1 articles | Viewed by 794 | Submission Open
Keywords: food processing technologies; bioactive constituents; nutrient retention; functional foods; bioavailability; non-thermal processing; sustainable processing; in vitro digestion models; metabolomics
(This special issue belongs to the Section Food Chemistry)
Plasmonic Metal Nanoparticles: From Synthesis to Major Applications
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 769 | Submission Open
Keywords: metal nanoparticles and nanoclusters; plasmonic metal nanoparticles; metal nanocomposites; shape-selected synthesis; size-selected synthesis; functional properties; high-resolution electron microscopy; surface plasmon resonance; interfacial properties; surface modification; catalysis; plasmonics; surface-enhanced Raman scattering; biomedical sensing; environmental sensing
(This special issue belongs to the Section Physical Chemistry)
Solid Waste and Fly Ash Chemical Treatment Methods—2nd Edition
edited by , and Huimin Liu
submission deadline 30 Apr 2026 | 1 articles | Viewed by 752 | Submission Open
Keywords: solid waste; fly ash; chemical treatment; waste management; thermal treatment; resource recovery; waste-to-energy; environmental chemistry
(This special issue belongs to the Section Green Chemistry)
Advancements in Enzyme Immobilization Techniques submission deadline 30 Apr 2026 | Viewed by 746 | Submission Open
Keywords: enzyme immobilization; biocatalysis; enzyme stabilization; reusability/recyclability; activity retention; operational stability; mass transfer limitation
(This special issue belongs to the Section Applied Chemistry)
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