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Bioactive Properties and Chemical Composition of Wild Edible Species, 2nd Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 1591

Special Issue Editor

Special Issue Information

Dear Colleagues,

Wild edible species have been collected and consumed for thousands of years due to their ability to enhance the flavour and aroma of a wide range of foods; thus, they are often used in traditional and gourmet dishes. Wild edible species also offer valuable nutritional benefits, including a high content of macro- and micronutrients, such as vitamins and minerals, and numerous bioactive compounds.

Many of these species are key ingredients in dietary patterns worldwide, and although they are consumed in low amounts, they can play an important role in preventing common chronic diseases and improving well-being. Among the various known phytochemicals, polyphenols stand out due to their prominent bioactivities and significantly contribute to the overall health benefits of dietary products. Although they are not classified as nutrients, the regular dietary intake of these secondary metabolites is associated with various health-protective effects. They are found throughout the plant kingdom, playing a role in defence mechanisms against biotic and abiotic stressors or other plant processes, and they exhibit significant variation in their chemical structures. Apart from polyphenols, other phytochemicals include flavonoids, isoflavonoids, anthocyanidins, phytoestrogens, terpenoids, carotenoids, limonoids, phytosterols, glucosinolates, and fibres, which are equally important in terms of their bioactivity and beneficial health effects. Finally, wild edible species are also rich in several compounds, such as fatty acids, free sugars, tocopherols and other vitamins, and organic acids, which may contribute to human health through their intrinsic bioactive properties.

Considering the wide distribution of phytochemicals in plant tissues, this Special Issue focuses on analyzing the chemical composition of wild and/or underutilized edible species, including wild edible species; further identifying bioactive properties related to the composition of phytochemicals and biosynthesis; and revealing the mechanisms of action behind these activities. Moreover, this Special Issue aims to investigate the effect that pre- and post-harvest factors may have on the composition of phytochemicals and the bioavailability of the detected compounds and their possible practical applications for pharmaceutical and nutraceutical purposes and/or in functional food products. This Special Issue invites both reviews and research papers, encompassing a wide range of multidisciplinary topics, including crop production and plant physiology, analytical chemistry and biochemistry, food chemistry, food processing, and pharmacology, among others.

Dr. Spyridon Petropoulos
Guest Editor

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Keywords

  • wild edible species
  • bioactive properties
  • polyphenols
  • antioxidant activity
  • antimicrobial properties
  • carotenoids
  • vitamins

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Related Special Issue

Published Papers (2 papers)

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Review

25 pages, 846 KB  
Review
Phytonutrient Profiles of Mistletoe and Their Values and Potential Applications in Ethnopharmacology and Nutraceuticals: A Review
by Maeleletse G. Mopai, Semakaleng Mpai, Johannes Van Staden and Ashwell R. Ndhlala
Molecules 2025, 30(22), 4390; https://doi.org/10.3390/molecules30224390 - 13 Nov 2025
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Abstract
Mistletoe species grow hemiparasitically on a wide spectrum of trees occurring in the tropical, subtropical and temperate zones. Mistletoe has been associated with fertility, vitality and fatality in humans. In the present review, we examine articles published in English and/or with the option [...] Read more.
Mistletoe species grow hemiparasitically on a wide spectrum of trees occurring in the tropical, subtropical and temperate zones. Mistletoe has been associated with fertility, vitality and fatality in humans. In the present review, we examine articles published in English and/or with the option to translate them into English on the distribution mechanism, ecological impact and value. This study aimed to interrogate and outline the phytonutrient profiling, ethnomedicinal and ethnopharmacological applications, toxicology and quality control of mistletoes, particularly the Loranthaceae and Viscaceae families. There are at least 1400 species of mistletoe belonging to these two families across the world. Humans have used mistletoe for years, and it has a rich history, mainly in traditional medicine. Recent research interests accompanied by investigations on mistletoe have made a major contribution to our understanding of the survival behavior and mechanisms of the species. This has prompted researchers to intensively investigate and justify its potential and applications in traditional medicine systems to further incorporate it into conventional scientific medicine processes. This study thoroughly outlines the nutritional and phytochemical constituents of various mistletoe species, as well as the factors that play a role in the process. The sections in this study dedicated to elaborating on the nutritional and phytochemical composition of mistletoe show that it is a plant species rich in nutrients and bioactive compounds, especially compared to its host. Its survival mechanism makes it possible for this plant species to contain significant quantities of both nutrients (proximate components and mineral elements) and bioactive compounds (viscin, alkaloids, phenolics and polyphenolics, tannins, flavonoids, terpenoids, glycosides, and saponins). Overall, mistletoe species have potential as medicinal plants, offering a range of health benefits and the ability to treat ailments (both communicable and non-communicable diseases). However, there are insufficient investigations and records of mistletoe’s toxicity, safety and quality control. Therefore, it is important to further investigate the potential applications, mechanisms of action, and optimal uses of mistletoe preparations and/or extracts. Full article
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18 pages, 931 KB  
Review
Unlocking the Alkaloid Biological Potential of Chili Pepper (Capsicum spp.), Cacao (Theobroma cacao L.), and Coffee (Coffea spp.) Byproducts: Characterization, Non-Conventional Extraction, Applications, and Future Perspectives
by Anahí Cárdenas, Luis Mojica, Luis Coronado-Cáceres and Gustavo A. Castillo-Herrera
Molecules 2025, 30(18), 3795; https://doi.org/10.3390/molecules30183795 - 18 Sep 2025
Viewed by 1045
Abstract
Chili peppers (Capsicum spp.), cacao (Theobroma cacao L.), and coffee (Coffea spp.) are important crops worldwide. Nearly 35%, 80%, and 45% of the respective fruits are underutilized or discarded, representing a considerable economic loss. This work reviews and analyzes the [...] Read more.
Chili peppers (Capsicum spp.), cacao (Theobroma cacao L.), and coffee (Coffea spp.) are important crops worldwide. Nearly 35%, 80%, and 45% of the respective fruits are underutilized or discarded, representing a considerable economic loss. This work reviews and analyzes the environmental factors that influence the concentration of the main alkaloids in these crops, including capsaicin, theobromine, and caffeine. Their reported anti-inflammatory, cardioprotective, neuroprotective, and cytotoxic properties are also reviewed. This work explores strategies for the revalorization of these crops, comparing alkaloid extraction methods that use non-conventional techniques, including supercritical fluid extraction (SFE), ultrasound-assisted extraction (UAE), high-pressure and -temperature extraction (HPTE), pressurized liquid extraction (PLE), pressurized hot water extraction (PHWE), enzyme-assisted extraction (EAE), and pulsed electric field-assisted extraction (PEFAE), and their combination to enhance the recovery of capsaicin, theobromine, and caffeine, leading to sustainable and innovative uses of these crops’ byproducts. Capsaicin, theobromine, and caffeine alkaloids are promising ingredients for the development of functional foods, cosmeceuticals, and pharmaceuticals. Full article
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