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Phytochemical Investigation of Bioactive Constituents from Medicinal Plants

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 868

Special Issue Editors


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Guest Editor
Department of Medicinal Plant and Mushroom Biotechnology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland
Interests: plant biotechnology; phytochemistry; pharmaceutical botany; HPLC analyses
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Medicinal Plant and Mushroom Biotechnology, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Krakow, Poland
Interests: plant biotechnology; phytochemistry; pharmaceutical botany; biochemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Natural products have been used for years to prevent and treat many diseases. Due to their rich and diverse chemical composition, medicinal plants are very intensively used in this area. There is still a huge demand for research on the chemical composition of plant materials, methods of isolating metabolites, their biological activity, their bioavailability, and their metabolism. Our Special Issue aims to create a forum for presenting the latest research in this field and presenting the achievements in this area to date in the form of review articles. It will be extremely valuable to present research on the chemical composition and biological activity of plant materials from various sources—natural sites, crops, and in vitro cultures. Research on isolated metabolites, their activity, the possibility of chemical structure transformations, bioavailability, and metabolism are also interesting.

We look forward to your contribution to this special issue.

Dr. Agnieszka Szewczyk
Dr. Inga Kwiecien
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • primary metabolites
  • secondary metabolites
  • biological activity
  • phytochemistry
  • natural products
  • HPLC-analysis
  • spectral analysis
  • medicinal plants

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Published Papers (1 paper)

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Research

19 pages, 11997 KiB  
Article
Identification and Characterization of Volatile Organic Compounds Based on GC-IMS Technology in Different Organs of Lilium brownii var. viridulum and After Bud-Removal and Non-Bud-Removal Treatments
by Xiaoling Li, Zhihui Wang, Chaowen Hou, Xiujuan Gong, Zexiang Liu, Yuhe Shi, Jianye Yan and Qiaozhen Tong
Molecules 2025, 30(6), 1238; https://doi.org/10.3390/molecules30061238 - 10 Mar 2025
Viewed by 564
Abstract
Lilium brownii var. viridulum (Longya lily) is a widely used medicinal and culinary plant in China that is valued for its potential applications and development opportunities. The bulbs of Longya lily contain a variety of active components; volatile oil, as one of the [...] Read more.
Lilium brownii var. viridulum (Longya lily) is a widely used medicinal and culinary plant in China that is valued for its potential applications and development opportunities. The bulbs of Longya lily contain a variety of active components; volatile oil, as one of the main biologically active compounds, has been widely studied, and the stems, leaves, and flowers of Longya lily are also rich in volatile organic compounds (VOCs) and related pharmacological effects, but the horizontal comparison of different organs of lily plants is lacking. In order to promote the sustainable development of resources, the composition characteristics and differences of bulbs, stems, leaves, and flowers, as well as two crop management methods (bud-removal and non-bud-removal), were comprehensively studied by GC-IMS technology in this study. Additionally, multivariate statistical analyses were used to identify the key components responsible for the observed differences among the plant organs and treatments. The research identified a total of 93 volatile organic compounds in Longya lily samples, primarily consisting of aldehydes, alcohols, ketones, and esters. If the VOCs of Longya lily are to be used as raw materials, it is advisable to choose flowers and leaves with a higher concentration of these components for harvesting. Notably, bulbs that were non-bud-removal exhibited a greater total content of volatile flavor substances compared to those that were treated with bud removal, with hexanal-D and (E)-2-hexenal-D being the most prevalent volatile organic compounds. This study provided theoretical support for the harvesting parts and crop management methods of Longya lily based on volatile organic compounds and promoted the high-quality development of the Longya lily industry. Full article
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