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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Minimally Invasive Strategies and New Techniques in Cardiovascular Surgery

edited by

Alexander Weymann

, Horatiu Suciu and

Marius Mihai Harpa

submission deadline 30 Jan 2026 | 1 articles | Viewed by 1381 | Submission Open

Keywords: minimally invasive; endoscopic surgery; mitral repair; mini-thoracotomy; hybrid approach; percutaneous therapy

(This special issue belongs to the Section Cardiology)

The Association Between Cardiovascular Disease and Lung Cancer

edited by

Francesk Mulita

and

Vasileios Leivaditis

submission deadline 30 Jan 2026 | Viewed by 208 | Submission Open

Keywords: cardiovascular disease; lung cancer; incidence; mortality; survival; radiotherapy; chemotherapy

(This special issue belongs to the Section Cardiology)

Medicine and Dentistry: New Methods and Clinical Approaches—2nd Edition

edited by

Stefano Rizza

and Rocco Franco

submission deadline 31 Jan 2026 | 16 articles | Viewed by 55803 | Submission Open

Keywords: oral health; new materials; medical approach; periodontal disease; bruxism; oral surgery

(This special issue belongs to the Section Dentistry and Oral Health)

Current and Future Trends in Dentistry and Oral Health

edited by

Eva Klarić

Bruno Špiljak

and

Luka Šimunović

submission deadline 31 Jan 2026 | 7 articles | Viewed by 22016 | Submission Open

Keywords: digital dentistry; artificial intelligence in dentistry; biomaterials; orthodontics; endodontics; periodontics; oral– systemic health; dental public health; esthetic dentistry; implantology

(This special issue belongs to the Section Dentistry and Oral Health)

Anterior Cruciate Ligament (ACL) Injury

edited by

Riccardo D'Ambrosi

and Alessandro Carrozzo

submission deadline 31 Jan 2026 | 6 articles | Viewed by 11284 | Submission Open

Keywords: anterior cruciate ligament; anterolateral ligament; arthroscopy; knee; sports medicine

(This special issue belongs to the Section Orthopedics)

Recent Advances in Anesthesiology and Pain Medicine

edited by Adam Rudnik and

Izabela Duda

submission deadline 31 Jan 2026 | 4 articles | Viewed by 11157 | Submission Open

Keywords: anesthetic procedures; perioperative monitoring; airway management; pain management; standards of anesthesia; perioperative care

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Novel Innovations in Diabetes Mellitus Prevention, Screening and Management

edited by

Anca Pantea Stoian

Teodor Salmen

and

Mihaela Adela Iancu

submission deadline 31 Jan 2026 | 4 articles | Viewed by 10106 | Submission Open

Keywords: diabetes mellitus; prevention; screening; complications; cardiovascular disease; neuropathy; retinopathy; nephropathy

(This special issue belongs to the Section Endocrinology)

Clinical Recent Research in Rehabilitation and Preventive Medicine

edited by Mihai Berteanu,

Marius Nicolae Popescu

and

Mădălina-Gabriela Iliescu

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8423 | Submission Open

Keywords: physical medicine; rehabilitation; injury prevention; wearable sensor devices (WSDs); biomechanics; regenerative medicine; musculoskeletal ultrasound (MSKUS); AI in medicine; telehealth; motion analysis

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Cardiovascular Disease: From Clinical Diagnosis to Management and Treatment

edited by Florin Mitu,

Maria-Magdalena Leon

and

Alexandra Maștaleru

submission deadline 31 Jan 2026 | 4 articles | Viewed by 7629 | Submission Open

Keywords: cardiovascular disease; cardiac rehabilitation; secondary prevention; innovative treatment; risk stratification

(This special issue belongs to the Section Cardiology)

Clinical Treatment of Neuroendocrine Neoplasm

edited by Michele Klain and

Leandra Piscopo

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3816 | Submission Open

Keywords: neuroendocrine neoplasms; neuroendocrine cell system; gastro-entero-pancreatic NENs; immunohistochemical analysis; Ki-67 index; mitotic count; somatostatin analogue therapy; antiproliferative effect; positron emission tomography/computed tomography (PET/CT); peptide receptor radionuclide therapy (PRRT)

(This special issue belongs to the Section Oncology)

Advances in Gynecological Cancer Research: Emerging Technologies and Future Therapeutic Strategies

edited by Jae-Yun Song and

Seongmin Kim

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3313 | Submission Open

Keywords: gynecological cancer; innovative surgical techniques; genomic profiling; personalized medicine; artificial intelligence (AI) in oncology; machine learning in diagnosis; cancer research technologies; future therapeutic strategies

(This special issue belongs to the Section Obstetrics and Gynecology)

Clinical Advances in Cardiopulmonary Bypass Surgery: Innovations and Impacts on Patient Outcomes

edited by

Irina-Iuliana Costache

Ștefania-Teodora Duca

and Lucian Stoica

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2371 | Submission Open

Keywords: cardiac surgery; cardiopulmonary bypass; patient outcome; surgical techniques; extracorporeal circulation; postoperative care; perfusion strategies

(This special issue belongs to the Section Cardiology)

Clinical Ophthalmology: Current Status and Future Challenges

edited by

Theodora Papamitsou

, Athanasios Karamitsos and

Sofia Karachrysafi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2037 | Submission Open

Keywords: clinical ophthalmology; ophthalmic pharmacology; biomarkers in eye diseases; ocular diagnostics; AI in ophthalmology; minimally invasive eye surgery; retinal diseases; gene therapy in ophthalmology; surgical innovations in ophthalmology; regenerative medicine for eye diseases

(This special issue belongs to the Section Ophthalmology)

Advances in Gastrointestinal Surgeries

edited by Matei Bratu, Bogdan Diaconescu and Florin Iordache

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1878 | Submission Open

Keywords: minimal invasive surgery; oncologic surgery; endoscopic surgery; rare cases

(This special issue belongs to the Section Surgery)

Research Progress in Oral and Periodontal Surgery

edited by

Pradeep Koppolu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1524 | Submission Open

Keywords: implants; biomarkers; mucogingival procedures; regeneration; lasers

(This special issue belongs to the Section Dentistry and Oral Health)

Update on Surgical Treatment for Ovarian Cancer

edited by

Christos R. Iavazzo

and

Victoria Psomiadou

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1401 | Submission Open

Keywords: ovarian cancer; surgical resection; ovariotomy; HIPEC (hyperthermic intraperitoneal chemotherapy); minimally invasive surgery (MIS); neoadjuvant chemotherapy (NACT); fertility-preserving procedures; AI-assisted technologies

(This special issue belongs to the Section Obstetrics and Gynecology)

Current Trends and Challenges in the Diagnosis and Management of Pediatric Knee Disorders

edited by Marcin K. Krzysztof Waśko

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1367 | Submission Open

Keywords: patellar instability in children; osteochondritis dissecans; discoid meniscus; pediatric ACL tears; meniscal injuries in children; tibial spine avulsion fracture; physeal injuries of the knee; genu valgum/genu varum; Blount’ s disease; juvenile idiopathic arthritis of the knee

(This special issue belongs to the Section Orthopedics)

Atrial Fibrillation: Clinical Complications and Treatment

edited by

Oskars Kalejs

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1004 | Submission Open

Keywords: atrial fibrillation [AFib]; rhythm control; rate control; triggers of AFib; antiarrhythmic pharmacy; upstream therapy; non-direct antiarrhythmic pharmacy; catheter ablation; prevention of stroke and systemic embolism; anticoagulants; AF-CARE concept

(This special issue belongs to the Section Cardiology)

Coronary CT Angiography in Coronary Artery Disease: Challenges and Future Opportunities

edited by

Nikolaos Ktenopoulos

and Andreas Synetos

submission deadline 31 Jan 2026 | Viewed by 340 | Submission Open

Keywords: coronary CT angiography; coronary artery disease; cardiac imaging; non-invasive imaging; INOCA/ANOCA

(This special issue belongs to the Section Cardiology)

Multiple Sclerosis: Recent Advances in Clinical Diagnosis and Treatment

edited by

Vasileios Giannopapas

, John Tzartos and Sotirios Giannopoulos

submission deadline 31 Jan 2026 | Viewed by 273 | Submission Open

Keywords: multiple sclerosis; demyelination; diagnostic criteria; treatment; disease-modifying therapies; comorbidities; rehabilitation; management

Diagnosis and Management of Upper Tract Urothelial Carcinomas

edited by

Yao-Chou Tsai

and

Shu-Yu Wu

submission deadline 31 Jan 2026 | Viewed by 193 | Submission Open

Keywords: upper urinary tract urothelial carcinoma (UTUC); nephroureterectomy; urinary tract biomarkers; chemotherapy; endoscopic management; molecular profiling; surgical treatment; target therapy

(This special issue belongs to the Section Urology & Nephrology)

From Conception to Birth: Embryonic Development and Disease

edited by

Paschalis Theotokis

, Soultana Meditskou and

Maria Eleni Manthou

submission deadline 1 Feb 2026 | 7 articles | Viewed by 29877 | Submission Open

Keywords: embryology; organogenesis; cell differentiation; gametes; reproduction; sex ratio; birth defects; pathophysiology; disease

Advances in Otorhinolaryngologic Diseases

edited by Karine Aubry, Mario Bilić and

Lana Kovač Bilić

submission deadline 15 Feb 2026 | 3 articles | Viewed by 4278 | Submission Open

Keywords: cochlear implant; ear surgery; otology; laryngeal cancer; oropharyngeal cancer; nasal polyposis; rhinoplasty; endoscopic sinus surgery; robotic surgery; dysphonia

(This special issue belongs to the Section Surgery)

Management of Gastrointestinal Disorders Related to Infectious Diseases and Medications

edited by

Amir Mari

and Fadi Abu Baker

submission deadline 15 Feb 2026 | 1 articles | Viewed by 2375 | Submission Open

Keywords: gastrointestinal symptoms; drug-related gastrointestinal disorders; gastrointestinal infections; diarrhea; infectious; intestinal microbiota; foodborne diseases; patient-centered outcomes

(This special issue belongs to the Section Gastroenterology & Hepatology)

Evaluation, Management, and Outcomes in Perioperative Medicine

edited by Yale Tung-Chen and

Francisco Javier García Sánchez

submission deadline 15 Feb 2026 | 2 articles | Viewed by 1840 | Submission Open

Keywords: perioperative medicine; surgical outcomes; prehabilitation; risk stratification; patient optimization; enhanced recovery; multimorbidity; postoperative complications; functional recovery; patient-centered care

(This special issue belongs to the Section Surgery)

New Insights into Cerebrovascular Disease

edited by Carolina Peña-Martínez

submission deadline 16 Feb 2026 | 2 articles | Viewed by 3424 | Submission Open

Keywords: cerebrovascular disease; stroke; small-vessel disease; vascular dementia; neuroinflammation

(This special issue belongs to the Section Neurology)

Craniomaxillofacial Surgery: Latest Innovations and Challenges

edited by Marius Octavian Pricop and Serban Talpos-Niculescu

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2801 | Submission Open

Keywords: maxillofacial and oral oncology; infections; orthognatic surgery; clefts; reconstructive surgery; bone regeneration; trauma

(This special issue belongs to the Section Surgery)

Abdominal Surgery: Innovative Techniques and Challenges

edited by

Tania Triantafyllou

and

Athanasios Pantelis

submission deadline 25 Feb 2026 | 2 articles | Viewed by 1585 | Submission Open

Keywords: minimally invasive surgery; abdominal surgery; surgical innovation; laparoscopy; robotic surgery; embedded systems; image-guided surgery

(This special issue belongs to the Section Surgery)

Advanced Ultrasound Technology and Its Application to Gynecologic Practice

edited by

Panagiotis Peitsidis

and Marco Gergolet

submission deadline 25 Feb 2026 | Viewed by 1507 | Submission Open

Keywords: gynecology; ultrasound; uterus; adnexa; pelvis; diagnosis

(This special issue belongs to the Section Obstetrics and Gynecology)

Application of Artificial Intelligence in Disease Diagnosis and Treatment

edited by Ricardo Martinez-Murillo and

Oscar Casanova Carvajal

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1261 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; medical diagnosis; clinical decision support; predictive modelling; medical imaging; personalised medicine; healthcare AI applications; explainable AI

(This special issue belongs to the Section Epidemiology & Public Health)

Advancements and Innovations in Dental Implantology

edited by

Roberta Gasparro

and

Adina Simona Coșarcă

submission deadline 25 Feb 2026 | Viewed by 234 | Submission Open

Keywords: bone augmentation; dental implants; tilted implants; preimplant reconstructive surgery

(This special issue belongs to the Section Dentistry and Oral Health)

Childhood and Adolescent Obesity: Risk Factors, Complications and Management

edited by Julian Hamilton-Shield and Dinesh Giri

submission deadline 25 Feb 2026 | Viewed by 231 | Submission Open

Keywords: childhood obesity; adolescent obesity; obesity risk factors; metabolic syndrome

(This special issue belongs to the Section Pediatrics)

Recent Advances in Coronary Heart Disease and Related Complications

edited by

Konstantinos Tsioufis

and

Panayiotis Iliakis

submission deadline 25 Feb 2026 | Viewed by 216 | Submission Open

Keywords: cardiology; hypertension; cardiovascular disease; coronary heart disease; structural heart disease; genomics; proteomics; interventional treatment; percutaneous coronary interventions; imaging; gene therapy

(This special issue belongs to the Section Cardiology)

Advances in Obstetrics and Maternal-Fetal Medicine

edited by Nicolae Suciu and

Catalin G Herghelegiu

submission deadline 28 Feb 2026 | 8 articles | Viewed by 21778 | Submission Open

Keywords: prenatal diagnosis; fetal ultrasound; maternal-fetal medicine; genomic sequencing; non-invasive prenatal testing (NIPT); perinatal pathology; high-risk pregnancy

(This special issue belongs to the Section Obstetrics and Gynecology)

Clinical Profile and Treatment Response of Patients with Ocular Inflammation

edited by

Valeria Albano

and Giovanni Alessio

submission deadline 28 Feb 2026 | 4 articles | Viewed by 12287 | Submission Open

Keywords: ocular inflammation; anterior uveitis; posterior uveitis; intermediate uveitis; masquerade syndrome

(This special issue belongs to the Section Ophthalmology)

Optimizing Outcomes in Head and Neck Surgery

edited by Carmen Aurelia Mogoantă and Daniela Vrinceanu

submission deadline 28 Feb 2026 | 4 articles | Viewed by 10374 | Submission Open

Keywords: head and neck; surgery; oncology; outcomes; artificial intelligence; otology; biologics; immunotherapy; multidisciplinary approach

(This special issue belongs to the Section Surgery)

New Advances in Acute Stroke Rehabilitation

edited by Jong Bae Choi

submission deadline 28 Feb 2026 | 3 articles | Viewed by 9035 | Submission Open

Keywords: stroke rehabilitation; robotic rehabilitation; virtual reality; telerehabilitation; motor imagery training; transcranial magnetic stimulation (TMS); swallowing rehabillitation; gait; mirror therapy; kinesio taping; upper limb function

(This special issue belongs to the Section Neurology)

Diagnosis and Treatment of Adolescent Idiopathic Scoliosis

edited by

Laura Scaramuzzo

and

Calogero Velluto

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7006 | Submission Open

Keywords: adolescent idiopathic scoliosis; spinal deformities; diagnosis; surgical treatment; minimally invasive techniques; biomechanics; clinical outcomes; patient-centered care; multidisciplinary approaches

(This special issue belongs to the Section Orthopedics)

Multidisciplinary Approaches and Recent Advances in Anesthesiology and Critical Care

edited by Silvius Ioan Negoiţǎ,

Dan E. Corneci

and

Emanuel Moisa

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6302 | Submission Open

Keywords: general anesthesia; regional anesthesia; intensive care medicine; patient safety; perioperative medicine; ERAS; point-of-care ultrasound; medical simulation; personalized medicine

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Evolving Concepts in Clinical Cardiology

edited by

Riccardo Proietti

and

Andrea Silvio Giordani

submission deadline 28 Feb 2026 | 1 articles | Viewed by 3520 | Submission Open

Keywords: clinical cardiology; cardiovascular diseases; molecular diagnostics; personalized strategies; precision medicine; cardiac imaging; interventional cardiology; cardiovascular comorbidities

(This special issue belongs to the Section Cardiology)

Automated Insulin Delivery Systems in Pediatric Type 1 Diabetes: From Real-World Evidence to Future Perspectives

edited by

Stefano Passanisi

and

Bruno Bombaci

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2336 | Submission Open

Keywords: adolescents; algorithm; children; insulin pump; nutrition; patient-reported outcomes; quality of life

(This special issue belongs to the Section Endocrinology)

Advances in Cancer Cell Metastasis and Its Inhibition

edited by

Amit K. Tripathi

and

Yogesh Srivastava

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2132 | Submission Open

Keywords: cancer metastasis; tumor inhibition; cellular mechanisms; therapeutic strategies; molecular biology; signal transduction; tumor microenvironment; chemotherapy resistance; targeted therapy; biomarkers

(This special issue belongs to the Section Oncology)

Clinical Update on Optic Nerve Disorders

edited by Ingrida Janulevičienė

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1497 | Submission Open

Keywords: optic nerve; neurodegenerative disorders; glaucoma; optic neuritis; ischemic optic neuropathy

(This special issue belongs to the Section Ophthalmology)

Advances in the Diagnosis, Treatment and Prognosis of Hepatocellular Carcinoma—2nd Edition

edited by

Emidio Scarpellini

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1229 | Submission Open

Keywords: hepatocellular carcinoma; metabolic-associated fatty liver disease; hepatic disease

(This special issue belongs to the Section Gastroenterology & Hepatology)

Cutaneous Melanoma: Updating from Pathogenesis to Therapy

edited by

Catalin G. Manole

and

Dana Antonia Țăpoi

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1040 | Submission Open

Keywords: cutaneous melanoma; pathogenesis; surgery; diagnosis; biomarkers; melanoma management

(This special issue belongs to the Section Dermatology)

Advances in Minimally Invasive Spine Surgery: Technology Innovations and Complications Management

edited by Sravisht Iyer and

Atahan Durbas

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1039 | Submission Open

Keywords: minimally invasive techniques; spine surgery; fusion; robotic; image-guided surgery; endoscopic spine surgery; spinal deformity; spinal implants and biomaterials; patient outcomes; perioperative care

(This special issue belongs to the Section Orthopedics)

Spinal Surgery: Advances and Concerns

edited by Filippo Migliorini and Gaetano Pappalardo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 949 | Submission Open

Keywords: spine; surgery; minimally invasive; deformity; motion preservation; oncology; infections; trauma; complications; instrumentation; outcomes

(This special issue belongs to the Section Neurology)

Regenerative Dentistry: A New Paradigm in Oral Health Care

edited by

Raluca Cosgarea

and Felicia Gabriela Beresescu

submission deadline 28 Feb 2026 | 1 articles | Viewed by 521 | Submission Open

Keywords: regenerative dentistry; tissue engineering; stem cells; dental pulp regeneration; biomaterials; oral tissue repair; periodontal regeneration; craniofacial regeneration

(This special issue belongs to the Section Dentistry and Oral Health)

Advances in Echocardiography for Critical Care Management: Challenges and Innovations

edited by

Efstratios Karagiannidis

and Aristi Boulmpou

submission deadline 28 Feb 2026 | Viewed by 363 | Submission Open

Keywords: echocardiography; advanced cardiovascular imaging; cardiomyopathies

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Advances in Airway Surgery

edited by

Fernando J. Abelha

and Helder Pereira

submission deadline 28 Feb 2026 | Viewed by 359 | Submission Open

Keywords: airway management; airway surgery; airway trauma; minimally invasive airway surgery; reconstruction; airway stenosis; pediatric airway; endoscopic techniques; surgical innovations

(This special issue belongs to the Section Surgery)

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