Cardiac Disease in Pregnancy: Diagnosis, Management and Outcomes

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 25 June 2025 | Viewed by 523

Special Issue Editor


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Guest Editor
Department of Cardiovascular Medicine, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA
Interests: congenital heart disease; cardiac imaging and echocardiography; pregnancy and heart disease; marfan syndrome and aortopathies
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Special Issue Information

Dear Colleagues,

Cardiovascular disease is a major cause of non-obstetric maternal morbidity and mortality, with increasing prevalence over the last two decades. It affects close to 1% of pregnancies in the developed world and 4% in the developing world. Although rheumatic heart disease comprises the most common maternal cardiac disease in the developing world, congenital heart disease is the most common maternal cardiac disease in the Western world. Optimal care for pregnant patients is best delivered by a multidisciplinary team which includes specialties such as cardiologists, maternal–fetal medicine specialists, anesthesiologists, geneticists, cardiovascular interventionalists and cardiac surgeons. The increased prevalence has led to the development and growth of the cardio-obstetrics field and related clinics worldwide.

Dr. David S. Majdalany
Guest Editor

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Keywords

  • maternal cardiac disease
  • cardio-obstetrics
  • pregnancy and heart disease
  • cardiac disease in pregnancy
  • maternal-fetal medicine

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Published Papers (1 paper)

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14 pages, 264 KiB  
Review
Pregnancy-Related Heart Disease in the Emergency Department
by Nicole R. Hodgson, Rachel A. Lindor, Jessica Monas, Kimberly Heller, Patrick Kishi, Aaron Thomas, Cody Petrie, Lauren B. Querin, Andrej Urumov and David S. Majdalany
J. Pers. Med. 2025, 15(4), 148; https://doi.org/10.3390/jpm15040148 - 8 Apr 2025
Viewed by 291
Abstract
Pregnancy induces significant physiologic changes that impact the cardiovascular system, potentially exacerbating pre-existing cardiac conditions or precipitating new illnesses. Pregnant patients with cardiac emergencies pose unique challenges, as standard interventions may pose risks to the developing fetus. This article aims to enhance emergency [...] Read more.
Pregnancy induces significant physiologic changes that impact the cardiovascular system, potentially exacerbating pre-existing cardiac conditions or precipitating new illnesses. Pregnant patients with cardiac emergencies pose unique challenges, as standard interventions may pose risks to the developing fetus. This article aims to enhance emergency physicians’ confidence in managing pregnancy-related cardiac emergencies by providing a structured approach to initial evaluation and stabilization. We review eight common categories of pregnancy-associated cardiac illness: gestational hypertension and pre-eclampsia, cardiomyopathy, arrhythmias, valvular disease, aortopathies, congenital heart disease and pulmonary hypertension, coronary disease, and anticoagulation-related complications. For each condition, we summarize relevant pregnancy-specific pathophysiology and outline evidence-based, personalized emergency management strategies. Full article
(This article belongs to the Special Issue Cardiac Disease in Pregnancy: Diagnosis, Management and Outcomes)
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