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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Urologic Disorders: Advances in Diagnosis and Therapy

edited by Carmen Gonzalez-Enguita and

Alberto Budía-Alba

submission deadline 15 Oct 2026 | Viewed by 267 | Submission Open

Keywords: prostatic hyperplasia; urinary incontinence; urothelial carcinoma; minimally invasive surgery; kidney stone; urinary tract infection

(This special issue belongs to the Section Nephrology & Urology)

Advances in Coronary Heart Disease: From Diagnosis to Long-Term Care

edited by

Marco Cirillo

and Cristian Leva

submission deadline 15 Oct 2026 | Viewed by 240 | Submission Open

Keywords: coronary heart disease; myocardial ischemia; percutaneous coronary intervention; coronary artery bypass surgery; left ventricular reconstruction; coronary diagnostic; coronary microvascular dysfunction; personalized medicine

(This special issue belongs to the Section Cardiology)

Clinical Management of Pemphigus

edited by

Cezary Kowalewski

submission deadline 15 Oct 2026 | Viewed by 233 | Submission Open

Keywords: pemphigus; pemphigus IgA; paraneoplastic pemphigus; cell–cell contact proteins and diagnostic procedures; novel therapies

(This special issue belongs to the Section Dermatology)

Otolaryngologic Clinical Findings and Management Across the Spectrum of Idiopathic Intracranial Hypertension

edited by Bülent Mamikoǧlu

submission deadline 15 Oct 2026 | Viewed by 211 | Submission Open

Keywords: idiopathic intracranial hypertension; intracranial pressure dysregulation; pulsatile tinnitus; venous sinus stenosis; CSF–inner ear coupling; vestibular migraine; dizziness and vertigo; aural fullness; glymphatic system; Chiari malformation; otologic manifestations of IIH; endovascular treatment; acetazolamide therapy

(This special issue belongs to the Section Otolaryngology)

Current Challenges and Innovations in Spine Deformity: Biomechanics, Imaging and AI-Driven Analysis

edited by Dong-Ho Kang

submission deadline 16 Oct 2026 | 4 articles | Viewed by 4439 | Submission Open

Keywords: spinal deformity; cervical deformity; biomechanics; postural alignment; sagittal imbalance; medical imaging; radiographic analysis; artificial intelligence; machine learning; deep learning; phenotyping; computer-assisted diagnosis; predictive modeling; surgical planning

(This special issue belongs to the Section Orthopedics)

Haemodialysis and Peritoneal Dialysis: Current Clinical Practices and Innovations

edited by

Susanne Angermann

submission deadline 16 Oct 2026 | 1 articles | Viewed by 912 | Submission Open

Keywords: haemodialysis; peritoneal dialysis; end-stage kidney disease; chronic kidney disease; nephrology

(This special issue belongs to the Section Nephrology & Urology)

Contemporary Treatment of Complement-Mediated Diseases

edited by

Daniel Turudić

and Danko Milošević

submission deadline 16 Oct 2026 | Viewed by 259 | Submission Open

Keywords: complement-mediated diseases; complement activation; atypical hemolytic uremic syndrome; C3 glomerulopathy; thrombotic microangiopathy; complement inhibitors; kidney transplantation; antibody-mediated rejection; complement dysregulation; genetic testing; kidney failure; dialysis; kidney transplantation; kidney allograft rejection

(This special issue belongs to the Section Nephrology & Urology)

Advances and Clinical Updates in the Gastrointestinal and Abdominal Diseases

edited by Elissavet Anestiadou, Savvas Symeonidis and Ioannis Mantzoros

submission deadline 19 Oct 2026 | 1 articles | Viewed by 644 | Submission Open

Keywords: gastrointestinal surgery; minimally invasive surgery; enhanced recovery; digestive oncology; inflammatory bowel disease; abdominal wall reconstruction; biomaterials; perioperative management

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Acute Ischemic Stroke Management Strategies

edited by

Marta Iacobucci

submission deadline 20 Oct 2026 | 8 articles | Viewed by 15568 | Submission Open

Keywords: mechanical thrombectomy; leptomeningeal collateral circulation; neuroprotection; reperfusion injury; ischemic penumbra

(This special issue belongs to the Section Clinical Neurology)

Clinical Management of Pediatric Heart Diseases

edited by

Michele Lioncino

submission deadline 20 Oct 2026 | 11 articles | Viewed by 12137 | Submission Open

Keywords: pediatric heart diseases; children; pediatric cardiology; congenital heart disease; clinical management; congenital heart surgery; outcome

(This special issue belongs to the Section Clinical Pediatrics)

Chronic Disease Management and Rehabilitation in Older Adults

edited by

Justyna Mazurek

submission deadline 20 Oct 2026 | 7 articles | Viewed by 11516 | Submission Open

Keywords: chronic disease; older adults; geriatric rehabilitation; holistic physiotherapy; physical activity; health outcomes; elderly people; geriatric care; health promotion

(This special issue belongs to the Section Geriatric Medicine)

Clinical Challenges and Innovations in Cochlear Implantation and Hearing Rehabilitation

edited by

Meredith Holcomb

submission deadline 20 Oct 2026 | 10 articles | Viewed by 10235 | Submission Open

Keywords: cochlear implant outcomes; clinical efficiency; barriers to care; cochlear implant surgery; cochlear implant referral; cochlear implant evaluation; cochlear implant candidacy; rehabilitation; rehabilitation strategies; quality of life

(This special issue belongs to the Section Otolaryngology)

Acute Myeloid Leukemia: Latest Advances in Diagnostics, Therapeutic Strategies and Clinical Management: 2nd Edition

edited by Michael D. Diamantidis

submission deadline 20 Oct 2026 | 5 articles | Viewed by 10101 | Submission Open

Keywords: ELN; ICC and WHO 2022 AML classifications; molecular AML diagnostics; AML biology; measurable residual disease (MRD); novel targeted AML therapies; AML immunotherapies; hematopoietic stem cell transplantation (HSCT)

(This special issue belongs to the Section Hematology)

Clinical Management of Patients with Heart Failure: 3rd Edition

edited by

Cristina Tudoran

submission deadline 20 Oct 2026 | 10 articles | Viewed by 9195 | Submission Open

Keywords: acute heart failure; chronic heart failure; treatment options; management of heart failure; lifestyle changes; diagnosis of heart failure

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Update on Thoracic Trauma

edited by

Duilio Divisi

submission deadline 20 Oct 2026 | 6 articles | Viewed by 8427 | Submission Open

Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation

(This special issue belongs to the Section Respiratory Medicine)

Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases

edited by

Calin Pop

and

Antoniu Petris

submission deadline 20 Oct 2026 | 5 articles | Viewed by 8290 | Submission Open

Keywords: echocardiography; cardiac diseases; 3D echo; stress; myocardial strain; intracardiac; subclinical cardiac disease

(This special issue belongs to the Section Cardiology)

Clinical Management of Corneal Diseases

edited by Hyeck Soo Son

submission deadline 20 Oct 2026 | 3 articles | Viewed by 7703 | Submission Open

Keywords: corneal diseases; keratoconus; corneal dystrophy; corneal ectasia; corneal transplantation; DMEK; DSAEK; kerato-prosthesis; crosslinking; ICRS; CAIRS; Bowman layer transplantation; treatment outcomes; clinical management

(This special issue belongs to the Section Ophthalmology)

Recent Developments in Hearing and Balance Disorders: 2nd Edition

edited by

Juan Carlos Amor-Dorado

submission deadline 20 Oct 2026 | 4 articles | Viewed by 7407 | Submission Open

Keywords: ear; otology; audiology; hearing disorders; deafness; hearing loss; autoimmunity; ENT; inflammation; vertigo; imbalance

(This special issue belongs to the Section Otolaryngology)

Advances in Maternal Fetal Medicine

edited by

Georgios Eleftheriou

and Anna Franca Cavaliere

submission deadline 20 Oct 2026 | 4 articles | Viewed by 6782 | Submission Open

Keywords: drugs use during pregnancy; fetal treatment; pregnancy complications; infectious diseases; neonatal poor adaptation syndrome

(This special issue belongs to the Section Obstetrics & Gynecology)

Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy

edited by

Carlo Brembilla

, Francesco Costa and Filippo Maria Polli

submission deadline 20 Oct 2026 | 4 articles | Viewed by 5963 | Submission Open

Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g., kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction

(This special issue belongs to the Section Clinical Neurology)

Pediatric Dentistry: Real-World Clinical Insights

edited by

Ruth M. Santamaría

submission deadline 20 Oct 2026 | 4 articles | Viewed by 5449 | Submission Open

Keywords: pediatric dentistry; minimally invasive dentistry; new technologies; biomaterials; innovative management approaches; caries management; pulp management; dental trauma; molar incisor hypomineralization; public health services research; epidemiological research; translational research

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Insights and Emerging Techniques in Interventional Cardiology

edited by

Giuseppe Panuccio

submission deadline 20 Oct 2026 | 1 articles | Viewed by 5059 | Submission Open

Keywords: percutaneous coronary intervention; coronary imaging; intravascular ultrasound; IVUS; computed tomography; optical coherence tomography; OCT; chronic total occlusions; drug-coated balloons; bifurcations; calcified coronary lesions; rotational atherectomy; intravascular lithotripsy; acute coronary syndromes; chronic coronary syndromes

(This special issue belongs to the Section Cardiology)

Recent Developments in Gynecological Endocrinology: 2nd Edition

edited by

Błażej Męczekalski

submission deadline 20 Oct 2026 | 2 articles | Viewed by 4901 | Submission Open

Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause

(This special issue belongs to the Section Obstetrics & Gynecology)

Heart Failure: Treatment and Clinical Perspectives

edited by Geza Halasz, Domenico Gabrielli and Francesco Grigioni

submission deadline 20 Oct 2026 | 6 articles | Viewed by 4821 | Submission Open

Keywords: heart failure; chronic heart failure; acute heart failure; treatment; cardiac imaging; diagnostics; patient outcomes; prognosis

(This special issue belongs to the Section Cardiology)

Skin Cancer: Prevention, Diagnosis, Quality of Life and Treatment Outcomes

edited by Athanassios A. Kyrgidis and

Aimilios Lallas

submission deadline 20 Oct 2026 | 5 articles | Viewed by 4815 | Submission Open

Keywords: skin cancer; melanoma; squamous cell carcinoma; basal cell carcinoma; clinical biomarkers; dermoscopy; quality of life

(This special issue belongs to the Section Dermatology)

Intrarenal Surgery for Kidney Stones and Other Kidney Diseases

edited by Razvan Multescu

submission deadline 20 Oct 2026 | 4 articles | Viewed by 4801 | Submission Open

Keywords: intrarenal surgery; flexible ureteroscopy; percutaneous nephrolithotomy (PCNL); Mini-PCNL; thulium laser; ureteral access sheaths; flexible and navigable suction (FANS); upper urinary tract urothelial tumors

(This special issue belongs to the Section Nephrology & Urology)

New Insights into Retinal Diseases

edited by Fabio Scarinci and Giulio Pocobelli

submission deadline 20 Oct 2026 | 5 articles | Viewed by 4334 | Submission Open

Keywords: optical coherence tomography; optical coherence tomography angiography; vitreoretinal diseases; retinal imaging analysis; biomarkers; segmentation; retinal ischemia; retinal blood flow; choroidal blood flow

(This special issue belongs to the Section Ophthalmology)

Clinical Implications of Pupil Function: Optical Quality, Visual Performance, and Neurological Biomarkers

edited by Pablo De Gracia and Héctor E. Soriano Baron

submission deadline 20 Oct 2026 | 1 articles | Viewed by 4232 | Submission Open

Keywords: pupil function; visual performance; intraocular lens (IOL) optimization; pupillometry diagnostics; neuro-ophthalmic biomarkers

(This special issue belongs to the Section Ophthalmology)

Recent Advances in Endocrine Surgery—2nd Edition

edited by

Gregorio Scerrino

submission deadline 20 Oct 2026 | 2 articles | Viewed by 4174 | Submission Open

Keywords: endocrine surgery; thyroid; thyroid cancer; parathyroid; parathyroidectomy; adrenal glands; disorders of hepatobiliary and gastrointestinal tract

(This special issue belongs to the Section General Surgery)

Clinical Updates in Imaging of Musculoskeletal Diseases

edited by

Federico Zaottini

and

Riccardo Picasso

submission deadline 20 Oct 2026 | 4 articles | Viewed by 4080 | Submission Open

Keywords: musculoskeletal imaging; ultrasound; magnetic resonance; sport imaging; rheumatology; nerve imaging

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Periodontology and Dental Implants: State of the Art and Future Perspectives

edited by Magda Mensi and

Davide Farronato

submission deadline 20 Oct 2026 | 2 articles | Viewed by 3881 | Submission Open

Keywords: periodontology; dental implants; regenerative dentistry; peri-implant diseases; digital dentistry; implant surface modifications; tissue engineering; oral microbiome; risk assessment; personalized treatment

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Advances and Clinical Outcomes of Endocrinology

edited by Stefana Catalina Bilha and

Cristina Preda

submission deadline 20 Oct 2026 | 2 articles | Viewed by 3710 | Submission Open

Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions

(This special issue belongs to the Section Endocrinology & Metabolism)

New Challenges and Perspectives in Surgical Treatment of Spinal Deformity

edited by Jung-Hee Lee

submission deadline 20 Oct 2026 | 5 articles | Viewed by 3515 | Submission Open

Keywords: adult spinal deformity; decompensation; kyphosis; lateral lumbar interbody fusion; orthopedic surgery; osteotomy; proximal junctional kyphosis; rod fracture

(This special issue belongs to the Section Orthopedics)

Hip and Knee Arthroplasty: Update on Clinical Management

edited by Maximilian F. Kasparek

submission deadline 20 Oct 2026 | 4 articles | Viewed by 3251 | Submission Open

Keywords: total hip arthroplasty (THA); total knee arthroplasty (TKA); revision arthroplasty; implant fixation; cemented; cementless; hybrid; alignment in TKA; mechanical alignment; kinematic alignment; restricted kinematic alignment; functional alignment; navigation; robotic-assisted surgery; patient-specific instrumentation; additive manufacturing; 3D printing; personalized implant

(This special issue belongs to the Section Orthopedics)

Orofacial Pain: Innovations in Treatment Modalities and Patient Care

edited by

Takahiko Nagamine

submission deadline 20 Oct 2026 | 1 articles | Viewed by 3053 | Submission Open

Keywords: orofacial pain; treatment; patient care; oral dysfunction; chronic pain; burning mouth syndrome; temporomandibular joint pain: oral cenesthopathy; atypical odontalgia; phantom bite syndrome

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Genitourinary Tumors and Radiation Therapy: Current Advances and Future Directions

edited by Shalini Moningi

submission deadline 20 Oct 2026 | 4 articles | Viewed by 2841 | Submission Open

Keywords: cancer; prostate cancer; bladder cancer; kidney cancer; radiation therapy

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Optimizing Outcomes in Emergency Medicine and Cardiopulmonary Resuscitation

edited by

Andreas S. Papazoglou

and

Dimitrios V. Moysidis

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2781 | Submission Open

Keywords: emergency medicine; cardiopulmonary resuscitation; prehospital care; outcome prediction; post-pesuscitation care; advanced life support; emergency response systems; medical ethics; simulation in medicine

(This special issue belongs to the Section Emergency Medicine)

Clinical Advances in Endodontic Dentistry

edited by

Luciano Giardino

and

Luigi Generali

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2640 | Submission Open

Keywords: antimicrobial agents; biofilm; confocal laser scanning microscopy; endodontic materials; irrigants; microbiome; micro-CT; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Peritoneal Dialysis and Hemodialysis: Early and Late Outcomes

edited by

Keren Cohen-Hagai

and

David Pereg

submission deadline 20 Oct 2026 | 3 articles | Viewed by 2608 | Submission Open

Keywords: peritoneal dialysis; dialysis; hemodialysis; chronic kidney disease; end-stage renal disease

(This special issue belongs to the Section Nephrology & Urology)

Acute Kidney Injury: Current Challenges and Future Directions in Diagnosis and Treatment

edited by

Grazia Maria Virzì

submission deadline 20 Oct 2026 | 3 articles | Viewed by 2574 | Submission Open

Keywords: acute kidney injury (AKI); biomarkers; precision nephrology; AKI-to-CKD transition, renal replacement therapy (RRT); subclinical AKI; sepsis-associated AKI; renal recovery

(This special issue belongs to the Section Nephrology & Urology)

New Insights in Joint Arthroplasty—2nd Edition

edited by

Richard Lass

submission deadline 20 Oct 2026 | 4 articles | Viewed by 2514 | Submission Open

Keywords: total hip arthroplasty; total knee arthroplasty; robotic-assisted technology and navigation; modern implant materials; modern implant fixation techniques; alignment in TKA; spinopelvic alignment in THA

(This special issue belongs to the Section Orthopedics)

Retinal Diseases: Emerging Therapies and Vision Rehabilitation

edited by

Hisanori Imai

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2509 | Submission Open

Keywords: vitreoretinal disorder; vitrectomy; digital assisted vitrectomy; intraoperative optical coherence tomography; diabetic retinopathy; epiretinal membrane

(This special issue belongs to the Section Ophthalmology)

Advances in Cervical Spine Surgery: Techniques, Outcomes, and Complications

edited by

Bartosz Godlewski

and Tae Sik Goh

submission deadline 20 Oct 2026 | 5 articles | Viewed by 2424 | Submission Open

Keywords: cervical spine; fusion assessment; surgical outcomes; cervical alignment; radiological measurements; subsidence; surgical complications

(This special issue belongs to the Section Orthopedics)

Bruxism and Temporomandibular Disorders: Assessment and Clinical Insights

edited by

Aneta Wieczorek

Małgorzata Kulesa-Mrowiecka

and

Michał Ginszt

submission deadline 20 Oct 2026 | 4 articles | Viewed by 2241 | Submission Open

Keywords: bruxism; temporomandibular disorders; TMD; clinical assessment; diagnosis; orofacial pain; masticatory system; interdisciplinary management

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Sights in Retinal Diseases Therapeutics: Innovation and Clinical Practice

edited by

Giacomo Boscia

Pasquale Viggiano

, Stefano Dore and Alfonso Savastano

submission deadline 20 Oct 2026 | 3 articles | Viewed by 2213 | Submission Open

Keywords: retinal diseases; central serous chorioretinopathy; age-related macular degeneration; eye diseases; diabetic retinopathy

(This special issue belongs to the Section Ophthalmology)

Prostate Surgery: The Latest Advances and Future Trends

edited by Akhil K. Das and

Bruce Gao

submission deadline 20 Oct 2026 | 1 articles | Viewed by 2111 | Submission Open

Keywords: benign prostatic hyperplasia (BPH); minimally invasive surgical therapies (MIST); laser enucleation (HoLEP, ThuLEP); Aquablation; Rezum; robotic prostatectomy; anatomic enucleation

(This special issue belongs to the Section Nephrology & Urology)

Innovations in Surgical and Medical Approaches of Urologic Oncology

edited by

Sung Han Kim

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2086 | Submission Open

Keywords: urologic oncology; robotic surgery; immunotherapy; targeted therapy; image-guided techniques; personalized medicine; minimally invasive surgery; focal therapy

(This special issue belongs to the Section Nephrology & Urology)

Advances in Clinical Craniofacial Reconstructive Surgery

edited by Rami S. Kantar

submission deadline 20 Oct 2026 | 2 articles | Viewed by 2047 | Submission Open

Keywords: craniofacial; craniofacial conditions; craniofacial surgery; cleft; cleft lip; cleft palate; reconstructive surgery; craniofacial anomalies

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Surgical Insights into Foot and Ankle Diseases

edited by Konstantinos Tsikopoulos

submission deadline 20 Oct 2026 | 1 articles | Viewed by 1982 | Submission Open

Keywords: lower limb surgery; infection research; foot and ankle

(This special issue belongs to the Section Orthopedics)

Paradigm Changes in Cardiac Surgery and Interventional Cardiology

edited by

Miklos Bitay

submission deadline 20 Oct 2026 | 2 articles | Viewed by 1848 | Submission Open

Keywords: cardiac surgery; trans-catheter interventions; ischaemic heart disease; structural heart disease; electrophysiological interventions; state-of-the-art techniques; golden standards; therapeutic guidelines

(This special issue belongs to the Section Cardiology)

Displaying special issue 301-350 on page 7 of 30.

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