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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovative Approaches to the Epidemiology, Diagnosis, and Treatment of Systemic Sclerosis

edited by

Antonio-Javier Chamorro

submission deadline 25 Sep 2026 | Viewed by 263 | Submission Open

Keywords: systemic sclerosis; scleroderma; epidemiology; biomarkers; personalized therapy; therapeutic strategies

(This special issue belongs to the Section Clinical Neurology)

Diagnosis, Treatment and Prognosis of Benign Prostatic Hyperplasia and Prostate Cancer

edited by Christian Wetterauer

submission deadline 25 Sep 2026 | Viewed by 227 | Submission Open

Keywords: benign prostatic hyperplasia; prostate cancer; urology; urological oncology; oncological outcomes; risk stratification; benign prostatic obstruction; minimally invasive techniques; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Challenges and Clinical Surveillance in Cerebral Aneurysm Management

edited by Joseph Antonios

submission deadline 25 Sep 2026 | Viewed by 225 | Submission Open

Keywords: intracranial aneurysm; cerebral aneurysm surveillance; risk stratification; aneurysm progression; vascular inflammation

(This special issue belongs to the Section Clinical Neurology)

Lifelong Care in Congenital Heart Disease

edited by

Cristina Ciuca

submission deadline 25 Sep 2026 | Viewed by 215 | Submission Open

Keywords: fetal echocardiography; pediatric cardiology; adults with congenital heart disease (ACHD); transition of care; cardio-obstetrics; heart failure; pregnancy; advanced imaging; echocardiography; cardiovascular risk prevention

(This special issue belongs to the Section Cardiovascular Medicine)

Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment

edited by Francesco Melillo

submission deadline 28 Sep 2026 | 3 articles | Viewed by 7680 | Submission Open

Keywords: aortic stenosis; mitral stenosis; TAVI

(This special issue belongs to the Section Cardiology)

Management of Female Pelvic Floor Disorders and Incontinence

edited by Luis López Fando

submission deadline 28 Sep 2026 | 2 articles | Viewed by 2212 | Submission Open

Keywords: pelvic floor disorders; urinary incontinence; pelvic organ prolapse; reconstructive urology; voiding dysfunction; multidisciplinary care; surgical techniques; urodynamics; patient-centered outcomes; digital learning in urology

(This special issue belongs to the Section Nephrology & Urology)

Current Challenges in Oral Surgery and Pathology

edited by

Christian Bacci

submission deadline 28 Sep 2026 | 2 articles | Viewed by 2015 | Submission Open

Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Clinical Perspective in Kidney Transplantation

edited by Nikolina Bašić-Jukić

submission deadline 29 Sep 2026 | 7 articles | Viewed by 6087 | Submission Open

Keywords: kidney transplantation; outcomes; desensitization; xenotransplantation; transplant nephropathology; multiorgan transplantations; post-transplant complications; inequities in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Glaucoma: Diagnosis and Management Insights

edited by

Stamatios Lampsas

and Efthymios Karmiris

submission deadline 29 Sep 2026 | 3 articles | Viewed by 2480 | Submission Open

Keywords: glaucoma; risk factors; progression; novel biomarkers; diagnosis; management

(This special issue belongs to the Section Ophthalmology)

New Insights into Cardiovascular Radiology

edited by Amalia Lupi and

Riccardo Cau

submission deadline 29 Sep 2026 | 3 articles | Viewed by 1727 | Submission Open

Keywords: CMR; tissue characterization; 4Dflow; CCTA; photon counting CT; plaque characterization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Advances in Musculoskeletal Physiotherapy: Exercise, Manual Therapy and Invasive Physiotherapy

edited by

Marcos José Navarro-Santana

and Ignacio Cancela-Cilleruelo

submission deadline 30 Sep 2026 | 6 articles | Viewed by 21816 | Submission Open

Keywords: musculoskeletal disorders; exercise therapy; manual therapy; invasive physical therapy; rehabilitation

(This special issue belongs to the Section Orthopedics)

Catheter Ablation of Cardiac Arrhythmias: Current Updates and Perspectives: 2nd Edition

edited by

Shaojie Chen

submission deadline 30 Sep 2026 | 3 articles | Viewed by 7176 | Submission Open

Keywords: ablation; arrhythmia; electrophysiology; atrial fibrillation; atrial flutter; atrial tachycardia; mapping; supraventricular tachycardia; ventricular arrhythmia

(This special issue belongs to the Section Cardiology)

Clinical Updates on Dyslipidemia

edited by

Nathan Wong

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5105 | Submission Open

Keywords: dyslipidemia; cardiovascular disease; prevention; treatment; risk factors

(This special issue belongs to the Section Cardiovascular Medicine)

Artificial Intelligence in Women’s Health and Medicine: Improving Clinical Practice, Diagnosis, Treatment Management and Patient Experiences

edited by

Shivaram Poigai Arunachalam

and Nasibeh Zanjirani Farahani

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4221 | Submission Open

Keywords: women’s health; artificial intelligence; machine learning; personalized medicine; reproductive health; health equity; social determinants of health; mental health; cancer; cardiovascular disease

(This special issue belongs to the Section Epidemiology & Public Health)

Clinical Advances in Hepatology

edited by

Dimitrios S. Karagiannakis

and

Theodoros Androutsakos

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4009 | Submission Open

Keywords: cirrhosis; portal hypertension; non-invasive tests; viral hepatitis; MASLD; HCC

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Modern Oral Surgery and Periodontology: Technological Advances, Innovation, and Clinical Applications

edited by Rafał Wiench and

Wojciech Niemczyk

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1323 | Submission Open

Keywords: oral surgery; periodontology; periodontal regeneration; implant dentistry; peri-implant diseases, guided surgery; biomaterials; platelet concentrates (PRF, PRP); bone regeneration

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Targeted Management of Orofacial Pain: From Pharmacology to Temporomandibular Joint Surgery

edited by

Matteo Val

Luca Guarda-Nardini

and Giulia Ottaviani

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1301 | Submission Open

Keywords: orofacial pain; chronic orofacial pain; neuropathic pain; pharmacological management; temporomandibular joint disorders; degenerative TMJ disease; conservative treatment; surgical management

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Burnout and Anxiety in Clinical and Occupational Contexts: Mental Health, Work-Related Stress, and Vulnerable Populations

edited by

Patricia Catalá

and

Cecilia Peñacoba-Puente

submission deadline 30 Sep 2026 | 1 articles | Viewed by 923 | Submission Open

Keywords: mental health; burnout; anxiety; occupational stress; women’s mental health; perinatal mental health; healthcare professionals; work-related stress; psychosocial factors; clinical interventions

(This special issue belongs to the Section Mental Health)

Interplay of Motility, Microbiota, and Function: New Insights into GI Disorders, IBS, and SIBO

edited by Tsachi Tsadok Perets

submission deadline 30 Sep 2026 | 1 articles | Viewed by 839 | Submission Open

Keywords: gastrointestinal motility; irritable bowel syndrome (IBS); small intestinal bacterial overgrowth (SIBO); gut microbiota; functional gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Updates and Advances in Aplastic Anemia and Other Bone Marrow Failures

edited by

Alicia Rovo

, Beatrice Drexler and Olaia Naveiras

submission deadline 30 Sep 2026 | Viewed by 465 | Submission Open

Keywords: aplastic anemia; severe aplastic anemia (SAA); bone marrow failures; paroxysmal nocturnal hemoglobinuria (PNH); inherited bone marrow failures

(This special issue belongs to the Section Hematology)

Acute Care Surgery: The Evolution of a Modern Specialty

edited by Mayur Narayan

submission deadline 30 Sep 2026 | Viewed by 342 | Submission Open

Keywords: acute care surgery; emergency surgery; health equity; global surgery; trauma care; surgical workforce; surgical in-novation; decision-making

(This special issue belongs to the Section Emergency Medicine)

Innovative Treatments and Management of Diabetes in Pregnancy

edited by Verónica Perea

submission deadline 30 Sep 2026 | Viewed by 259 | Submission Open

Keywords: diabetes in pregnancy; gestational diabetes mellitus; type 1 diabetes; continuous glucose monitoring; automated insulin delivery; innovative therapies; digital health

(This special issue belongs to the Section Endocrinology & Metabolism)

Update and Emerging Trends in Urological Surgery

edited by Yasmin Abu-Ghanem

submission deadline 30 Sep 2026 | Viewed by 240 | Submission Open

Keywords: urology; urological surgery; precision medicine; biomarkers; minimally invasive surgery; multidisciplinary care

(This special issue belongs to the Section Nephrology & Urology)

Current Concepts in Shoulder Arthroplasty—Degenerative Pathology, Scapular Morphology, Posture and Kinematics, Realignment Procedures, Fracture Reconstruction, and Outcome Measurement

edited by

Stefan Bauer

Allan W. Wang

and

William G. Blakeney

submission deadline 1 Oct 2026 | 3 articles | Viewed by 1764 | Submission Open

Keywords: reverse total shoulder arthroplasty; cuff tear arthropathy; osteoarthritis; proximal humeral fracture sequelae; revision; long-term outcome; implant design; biomechanics

(This special issue belongs to the Section Orthopedics)

Clinical Perspectives in Emerging Infectious Diseases

edited by

Steven Van Lelyveld

submission deadline 4 Oct 2026 | Viewed by 242 | Submission Open

Keywords: emerging infectious diseases; one health; arbovirus disease; avian influenza; hemorrhagic fever; coronavirus diseases; Nipah virus

(This special issue belongs to the Section Infectious Diseases)

Diagnosis and Treatment of Obstetrics and Gynecology Cancers

edited by

Gaspare Cucinella

submission deadline 5 Oct 2026 | 4 articles | Viewed by 12197 | Submission Open

Keywords: gynecological cancers; endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; vaginal cancer; breast cancer; surgery; radio-therapy; systemic treatment; immunotherapy; sentinel lymph node biopsy; minimally invasive surgery; fertility preservation; gestational trophoblastic disease

(This special issue belongs to the Section Obstetrics & Gynecology)

New Insights into Pediatric Otolaryngology: From Diagnosis to Minimally Invasive Therapies

edited by

Mariaconsiglia Santantonio

and

Luisa Bellussi

submission deadline 5 Oct 2026 | 3 articles | Viewed by 2395 | Submission Open

Keywords: pediatric otolaryngology; minimally invasive; early diagnosis; olfactory disorders; pediatric rhinology; pediatric airway; pediatric ENT; pediatric sleep disorders; pediatric diagnosis

(This special issue belongs to the Section Clinical Pediatrics)

Thoracic Radiochemoimmunotherapy for Non-Small Cell Lung Cancer (NSCLC): Evolving Techniques and Clinical Applications

edited by

Franz Zehentmayr

submission deadline 5 Oct 2026 | 1 articles | Viewed by 1309 | Submission Open

Keywords: radiotherapy; radiology; oncology; non-small cell lung cancer; real-world data; immunotherapy; radiation dose escalation

(This special issue belongs to the Section Oncology)

Current Progress and Future Directions in Orthodontics and Periodontology

edited by

Ligia Vaida

and

Ionut Luchian

submission deadline 5 Oct 2026 | Viewed by 353 | Submission Open

Keywords: orthodontics; periodontology; interdisciplinary treatment; orthodontic tooth movement; periodontal phenotype; digital dentistry; regenerative therapy; clinical outcomes; treatment planning; future perspectives of interdisciplinarity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Neuropathic Pain: From Prevention to Diagnosis and Management

edited by Enrico Martin

submission deadline 10 Oct 2026 | 2 articles | Viewed by 5666 | Submission Open

Keywords: neuropathic pain; clinical research; TMR; RPNI; preclinical studies; QoL; PROMS; translational medicine; pain mechanisms

(This special issue belongs to the Section Clinical Neurology)

New Insights into Clinical Application of Embolization Techniques

edited by

Bedros Taslakian

and Yan Epelboym

submission deadline 10 Oct 2026 | 3 articles | Viewed by 4153 | Submission Open

Keywords: embolization; interventional radiology; musculoskeletal embolization; uterine artery embolization; prostate artery embolization; vascular malformations; catheter-directed therapy

(This special issue belongs to the Section Vascular Medicine)

Current Trends and Future Challenges in Coronary Artery Disease

edited by Federica Agnello

submission deadline 10 Oct 2026 | 2 articles | Viewed by 1650 | Submission Open

Keywords: coronary artery disease; cardiovascular prevention; coronary computed tomography angiography (CCTA); CT-derived fractional flow reserve (FFR-CT); intracoronary imaging; residual risk; functional assessment; artificial intelligence in cardiology; percutaneous coronary intervention

(This special issue belongs to the Section Cardiology)

Treatment Strategies in Congenital Heart Disease: Current Practices and Future Directions

edited by Anastasia Schleiger, Julia Moosmann and

Antonia Schulz

submission deadline 10 Oct 2026 | 2 articles | Viewed by 1550 | Submission Open

Keywords: congenital heart disease; transcatheter management of congenital heart defects; surgical strategies for congenital heart defects; medical heart failure treatment; mechanical circulatory support; hybrid procedures; pulmonary hypertension; heart teams; multidisciplinary management; quality of life

(This special issue belongs to the Section Cardiology)

Clinical Advances and Insights in Cardiovascular Imaging

edited by Maurizio Cusmà Piccione

submission deadline 10 Oct 2026 | 2 articles | Viewed by 961 | Submission Open

Keywords: cardiovascular imaging; multimodality imaging; cardiac magnetic resonance; cardiac computed tomography; advanced echocardiography

(This special issue belongs to the Section Cardiovascular Medicine)

Biomarkers in Peripheral Artery Disease

edited by Ben Li

submission deadline 10 Oct 2026 | 1 articles | Viewed by 720 | Submission Open

Keywords: vascular diseases; biomarkers; diagnosis; prognosis; risk stratification; vascular inflammation; endothelial dysfunction; aneurysmal degeneration; imaging biomarkers; precision medicine

(This special issue belongs to the Section Vascular Medicine)

The Evolution of Knee Surgery: The Role of Robotics and Personalization

edited by

Joong Il Kim

submission deadline 10 Oct 2026 | 1 articles | Viewed by 652 | Submission Open

Keywords: robotic knee surgery; robot-assisted knee arthroplasty; personalized knee replacement; personalized alignment; total knee arthroplasty

(This special issue belongs to the Section Orthopedics)

Application of Artificial Intelligence in Cardiology

edited by

Matthias Unterhuber

submission deadline 13 Oct 2026 | 9 articles | Viewed by 15171 | Submission Open

Keywords: artificial intelligence; cardiology; clinical practice; valvular heart disease; arrhythmias; device therapy; machine learning

(This special issue belongs to the Section Cardiology)

Innovations in Parkinson’s Disease

edited by

Sneha Mantri

submission deadline 15 Oct 2026 | 5 articles | Viewed by 8193 | Submission Open

Keywords: Parkinson’s disease; parkinsonism; patient-reported outcomes; wearable technology; disease-modifying therapies; non-pharmacological therapies; care delivery; models of care

(This special issue belongs to the Section Clinical Neurology)

Clinical Diagnostics and Therapeutic Advances in Pregnancy Complications

edited by

Theresa Reischer

and

Gülen Yerlikaya-Schatten

submission deadline 15 Oct 2026 | 5 articles | Viewed by 7660 | Submission Open

Keywords: prenatal diagnosis; pre-eclampsia; gestational diabetes; pregnancy complications; preterm labor; congenital mal-formations; prenatal genetic testing

(This special issue belongs to the Section Obstetrics & Gynecology)

Pharmacotherapy and Patient Care in Rheumatoid Arthritis

edited by

Ryu Watanabe

submission deadline 15 Oct 2026 | 2 articles | Viewed by 6657 | Submission Open

Keywords: rheumatoid arthritis; pharmacotherapy; patient care; biomarkers; treatment outcomes

(This special issue belongs to the Section Immunology & Rheumatology)

Retinal Dystrophies—Structure and Function Relationship

edited by

Katarzyna Nowomiejska

submission deadline 15 Oct 2026 | 3 articles | Viewed by 4071 | Submission Open

Keywords: retinal dystrophies; structural changes; functional impairment; in retinal degenerative diseases; retinitis pigmentosa

(This special issue belongs to the Section Ophthalmology)

Orthopedic Surgery: Latest Advances and Future Prospects—2nd Edition

edited by Andrea Marinozzi and

Biagio Zampogna

submission deadline 15 Oct 2026 | 4 articles | Viewed by 3503 | Submission Open

Keywords: custom-made; regenerative; prosthetic; noninvasive surgery; robotic surgery; percutaneous surgery; minimally invasive surgery

(This special issue belongs to the Section Orthopedics)

Prenatal Diagnosis and Intervention: Shaping the Future of Maternal–Fetal Medicine

edited by

Misgav Rottenstreich

submission deadline 15 Oct 2026 | 4 articles | Viewed by 3284 | Submission Open

Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Transjugular Intrahepatic Portosystemic Shunt: Challenges and Perspectives—2nd Edition

edited by

Lorenzo Ridola

, Stefania Gioia and

Silvia Nardelli

submission deadline 15 Oct 2026 | 2 articles | Viewed by 2251 | Submission Open

Keywords: hepatic encephalopathy; spontaneous portal-systemic shunts; transjugular intrahepatic portosystemic shunt; cirrhosis; portal hypertension; sarcopenia; myosteatosis; gastrointestinal bleeding; ascites; non cirrhotic portal hypertension

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Liver Transplantation and Organ Perfusion

edited by Franziska A. Meister

submission deadline 15 Oct 2026 | 4 articles | Viewed by 1917 | Submission Open

Keywords: liver transplantation; extended criteria donors; ischemia–reperfusion injury; graft dysfunction; organ preservation; machine perfusion; normothermic perfusion; hypothermic perfusion; transplant outcomes

(This special issue belongs to the Section General Surgery)

Clinical Challenges in Endocrine Oncology

edited by

Francesco Dondi

submission deadline 15 Oct 2026 | 2 articles | Viewed by 1291 | Submission Open

Keywords: neuroendocrine tumors; thyroid cancer; adrenocortical carcinoma; pituitary adenoma; multiple endocrine neoplasia (MEN); hormone-secreting tumors

(This special issue belongs to the Section Endocrinology & Metabolism)

Contemporary Challenges and Advances in Pulmonary Embolism

edited by Roy Beigel, Shlomi Matetzky and Fernando Chernomordik

submission deadline 15 Oct 2026 | 1 articles | Viewed by 1156 | Submission Open

Keywords: pulmonary embolism; treatment; coagulation; venous thrombosis; thrombolysis; anticoagulation; risk stratification; PERT; CTEPH

(This special issue belongs to the Section Respiratory Medicine)

Comprehensive Approaches in Gastrointestinal Oncology: Focus on Colorectal, Gastric, and Pancreatic Cancer Treatment

edited by

Stefano Rausei

and

Georgios D. Lianos

submission deadline 15 Oct 2026 | 2 articles | Viewed by 940 | Submission Open

Keywords: colorectal cancer; gastric cancer; pancreatic cancer; biological staging; clinical staging; early tumors; locally advanced tumors; oligometastatic tumor; neoadjuvant approach; chemotherapy; radiotherapy; immunotherapy; radical surgery; conservative treatment; targeted therapy

(This special issue belongs to the Section Oncology)

Cardiac Surgery: Current Clinical Challenges and New Perspectives

edited by Sadeq Ali-Hasan-Al-Saegh and

Alexander Weymann

submission deadline 15 Oct 2026 | 3 articles | Viewed by 758 | Submission Open

Keywords: cardiac surgery; surgical challenges; innovations in cardiology; minimally invasive techniques; robotic-assisted surgery; artificial intelligence in cardiac surgery; postoperative management; quality improvement in cardiac surgery

(This special issue belongs to the Section Cardiology)

Clinical and Surgical Treatment for Orthopedic Trauma

edited by Mihnea Ioan Gabriel Popa

submission deadline 15 Oct 2026 | Viewed by 314 | Submission Open

Keywords: orthopedic surgery; orthopedic trauma; trauma surgery; musculoskeletal oncology; musculoskeletal biomaterials; infection management; complication management

(This special issue belongs to the Section Orthopedics)

Displaying special issue 201-250 on page 5 of 30.

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