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Orthopedic Surgery: Latest Advances and Future Prospects—2nd Edition
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Orthopedic Surgery: Latest Advances and Future Prospects—2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 15 April 2026 | Viewed by 684

Special Issue Editors

Prof. Dr. Andrea Marinozzi

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Guest Editor
1. Operative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, 00128 Rome, Italy
2. Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico Di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy
Interests: foot and ankle surgery; fracture management; lower limb arthroplasty
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Biagio Zampogna

E-Mail Website
Guest Editor
1. Operative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, 00128 Rome, Italy
2. Research Unit of Orthopaedic and Trauma Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico Di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy
3. BIOMORF Department of Biomedical, Dental, Morphological and Functional Images, Department of Orthopaedic and Trauma Surgery, University of Messina, A.O.U. Policlinico "G.Martino", Via Consolare Valeria 1, 98124 Messina, Italy
Interests: adult reconstruction; hip and knee arthroplasty; robotic surgery; perioperative optimization; arthroscopic surgery of the knee and shoulder
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Following the success of the first volume of this Special Issue (https://www.mdpi.com/journal/jcm/special_issues/61238DDZIP), we decided to launch a second volume to discuss a greater number of relevant topics.

The progress achieved in the last 10 years in orthopedic surgery is remarkable.

In particular, in prosthetic surgery, the evolution of the design and tribology of prosthetic components and the refinement of navigated and robotic techniques have certainly prolonged the survival of implants, improving the mechanics of neo-articulations, considerably improving patient satisfaction as a result.

Another innovative breakthrough that opens exciting prospects of research is the development of 3D printing to fabricate prosthetic elements and support the surgeon, enabling the realization of increasingly precise implants customized to the individual patient.

Finally, the remarkable development of new minimally invasive techniques for treating numerous orthopedic diseases should be considered.

In this Special Issue, we invite the authors to present articles on the advances in and perspectives regarding prosthetics and minimally invasive surgery.

Prof. Dr. Andrea Marinozzi
Prof. Dr. Biagio Zampogna
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • custom-made
  • regenerative
  • prosthetic
  • noninvasive surgery
  • robotic surgery
  • percutaneous surgery
  • minimally invasive surgery

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Published Papers (1 paper)

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Research

11 pages, 330 KB  
Article
Endoscopic Assistance in Minimally Invasive Repair of Acute Achilles Ruptures: A Prospective Observational Study Comparing Endoscopic-Assisted, Minimally Invasive, and Open Techniques
by Paolo Ceccarini, Marco Donantoni, Lorenzo Lucchetta, Andrea Marinozzi, Pierluigi Antinolfi, Giuseppe Rinonapoli and Auro Caraffa
J. Clin. Med. 2025, 14(22), 8117; https://doi.org/10.3390/jcm14228117 - 17 Nov 2025
Viewed by 454
Abstract
Background: The optimal management of acute Achilles tendon (AT) ruptures remains debated. Historically, surgical treatment has been preferred over conservative management because of a lower risk of rerupture. In recent decades, minimally invasive (MIS) and percutaneous techniques have been introduced to reduce [...] Read more.
Background: The optimal management of acute Achilles tendon (AT) ruptures remains debated. Historically, surgical treatment has been preferred over conservative management because of a lower risk of rerupture. In recent decades, minimally invasive (MIS) and percutaneous techniques have been introduced to reduce the complications associated with the traditional open surgery. Comparable clinical outcomes have been demonstrated, with a lower rate of general complications but a higher risk of sural nerve palsy. Endoscopic assistance has been finally proposed to improve intraoperative visualization and potentially decrease this risk, although its actual potential benefit remains uncertain. Methods: A prospective observational study including a total of 94 patients who underwent surgical treatment for acute subcutaneous AT rupture was conducted. 60 of the patients were male and 34 were female, with a mean age at the time of surgery of 42.5 [18–78] years. The patients were then divided into three groups according to the surgical procedure performed: endoscopic-assisted MIS technique (A, n = 30), Ma-Griffith minimally invasive technique (M-G/MISI) (B, n = 34) and traditional open surgery (C, n = 32). Same post-operative protocol. The mean follow-up was 32 months (24–60 months). Patients were evaluated by time taken to return to driving (RTD), to their usual work activities (RTW), and, in active patients, to sports activities (RTS) at a level comparable to that prior to the injury was recorded. Clinical outcomes were evaluated with Achilles tendon Total Rupture Score (ATRS) and Ankle Hindfoot American Orthopaedic Foot and Ankle Society (AH-AOFAS) scores. Results: Significant differences among groups were found for RTD (p = 0.001), RTW (p < 0.001), and ATRS (p < 0.001), while RTS (p = 0.46) and AOFAS (p = 0.41) did not differ significantly. Post hoc analyses showed that the M-G/MISI group achieved faster return to driving and work and higher ATRS compared with the open group (all p < 0.05). No significant differences were detected between M-G/MISI and endoscopic-assisted techniques. Conclusions: All three techniques achieved good functional outcomes and low complication rates. Endoscopic assistance allowed visualization of suture passage and confirmation of gap reduction, but no superiority was observed in clinical outcomes or sural nerve safety. The M-G/MISI approach was associated with faster return to activity and higher ATRS compared with open repair. Full article
(This article belongs to the Special Issue Orthopedic Surgery: Latest Advances and Future Prospects—2nd Edition)
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