Clinical Advances in Liver Transplantation and Organ Perfusion

Dear Colleagues,

The field of liver transplantation (LTx) continues to face substantial unresolved challenges. Donor organ shortage, increasing use of extended criteria donors, ischemia–reperfusion injury, and post-transplant graft dysfunction remain major limitations in clinical practice. Despite advances in surgical techniques, perioperative management, and preservation strategies, many fundamental problems in LTx are still not fully resolved.

In this context, organ perfusion technologies have emerged as a rapidly developing area in transplant medicine. Machine perfusion, including normothermic and hypothermic approaches, offers new opportunities for improved graft preservation, viability assessment, and organ reconditioning prior to transplantation. These strategies may enhance the utilization of marginal organs and improve post-transplant outcomes, while also raising important clinical and translational questions.

Importantly, this Special Issue is not limited to organ perfusion research. We welcome submissions covering the full spectrum of LTx, including donor and recipient selection, surgical and technical innovations, and short- and long-term outcomes. Studies focusing exclusively on LTx without organ perfusion technologies are equally encouraged.

We invite authors to submit original research articles and reviews addressing recent clinical advances in LTx for improving graft function and patient outcomes.

Dr. Franziska A. Meister
Guest Editor

Manuscript Submission Information

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