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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Situation and Challenges of Endovascular Treatment Strategies for Acute Ischemic Stroke
edited by
submission deadline 20 Jan 2026 | 1 articles | Viewed by 1172 | Submission Open
Keywords: acute ischemic stroke; endovascular treatment; imaging; management of ischemic stroke; system and strategy for acute ischemic stroke; multidisciplinary approach for acute ischemic stroke
(This special issue belongs to the Section Clinical Neurology)
Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition
edited by Jaime A. Hernández-Montfort
submission deadline 20 Jan 2026 | 1 articles | Viewed by 787 | Submission Open
Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement
(This special issue belongs to the Section Cardiology)
Eating Disorders: Current Epidemiology and Advances in Diagnosis and Treatment—Second Edition submission deadline 20 Jan 2026 | 1 articles | Viewed by 461 | Submission Open
Keywords: eating disorder; bulimia nervosa; anorexia nervosa; binge eating disorder; sociocultural context; epidemiology; di-agnosis; treatment; prevention
(This special issue belongs to the Section Mental Health)
Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome submission deadline 20 Jan 2026 | 1 articles | Viewed by 422 | Submission Open
Keywords: endodontics; apical periodontitis; pulpitis; root canal treatment; risk factors; treatment outcomes; regenerative endodontics
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Practice and Future Perspectives on Laryngeal Surgery submission deadline 20 Jan 2026 | 1 articles | Viewed by 370 | Submission Open
Keywords: laryngeal disorders; laryngeal surgery; microsurgery; endoscopic surgery; open surgery; laser surgery
(This special issue belongs to the Section Otolaryngology)
Endometriosis: Diagnosis and Treatment submission deadline 20 Jan 2026 | 1 articles | Viewed by 279 | Submission Open
Keywords: endometriosis; diagnosis; video laparoscopy with and without robotic assistance; chronic pelvic pain; fertility preservation; minimally invasive surgery; biomarkers; artificial intelligence in endometriosis; adenomyosis; and adenomyoma care; multidisciplinary care; personalized medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Advancements in the Treatment of Myeloproliferative Neoplasms and Myelodysplastic Syndromes
edited by Ivan Krečak, Marko Skelin and Zinaida Perić
submission deadline 20 Jan 2026 | 1 articles | Viewed by 279 | Submission Open
Keywords: myeloproliferative neoplasms; myelodysplastic syndromes; treatment; risk stratification; prognosis
(This special issue belongs to the Section Hematology)
Multiple Myeloma: Therapeutic and Management Strategies
edited by Terri Parker
submission deadline 20 Jan 2026 | Viewed by 187 | Submission Open
Keywords: multiple myeloma; frontline treatment; monoclonal antibodies; sequencing of treatment; immunotherapy; CAR T; Bi-specific T cell engagers; toxicity management
(This special issue belongs to the Section Hematology)
Innovations and Evolution of Extracorporeal Organ Support in Critical Care
edited by , and Antonella Tosi
submission deadline 20 Jan 2026 | Viewed by 104 | Submission Open
Keywords: critical care; extracorporeal organ support; critical care nephrology; cardiology; ARDS; sepsis; blood purification; liver support
(This special issue belongs to the Section Intensive Care)
Cardiopulmonary Resuscitation in the Emergency Care Unit
edited by , Felipe Fernández-Méndez, and
submission deadline 20 Jan 2026 | Viewed by 83 | Submission Open
Keywords: cardiopulmonary resuscitation; advanced life support; new technologies; special circumstances; emergency care unit
(This special issue belongs to the Section Emergency Medicine)
Beyond the Kidney: Managing Chronic Kidney Disease in the Era of Cardio-Metabolic-Kidney Syndrome submission deadline 20 Jan 2026 | Viewed by 82 | Submission Open
Keywords: chronic kidney disease; disease-modifying therapy; physical exercise; cardio-metabolic-kidney syndrome; SGLT2 in-hibitors; MRA; renal nutrition; innovative therapies; low protein diet
(This special issue belongs to the Section Nephrology & Urology)
Artificial Intelligence (AI) and Deep Learning (DL) in Medical Imaging submission deadline 20 Jan 2026 | Viewed by 75 | Submission Open
Keywords: artificial intelligence; deep learning; imaging; diagnosis; precision medicine; oncologic
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Preventive Strategies and Novel Treatments for Rheumatoid Arthritis
edited by
submission deadline 20 Jan 2026 | Viewed by 74 | Submission Open
Keywords: rheumatoid arthritis; antibodies; biologics; JAK; environment; susceptibility; therapeutic strategies
(This special issue belongs to the Section Immunology)
Artificial Intelligence (AI) in Dental Clinical Practice
edited by and Keiichiro Watanabe
submission deadline 20 Jan 2026 | Viewed by 73 | Submission Open
Keywords: artificial intelligence; dental diagnostics; machine learning; deep learning; digital dentistry; clinical decision support; diagnostic automation; data transparency; evidence-based dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations in Infertility Treatment and Assisted Reproductive Technologies (ARTs)
edited by Diana Alecsandru
submission deadline 20 Jan 2026 | Viewed by 69 | Submission Open
Keywords: infertility; assisted reproductive technology (ARTs); fertility preservation; in vitro fertilization (IVF); reproductive endocrinology
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Updates and Current Challenges in Obstetrical Anesthesia
edited by Michael Froelich
submission deadline 20 Jan 2026 | Viewed by 64 | Submission Open
Keywords: obstetrical anesthesia; clinical innovation; practice guidelines; neuraxial techniques; enhanced recovery; risk stratification; maternal safety; multimodal analgesia; health systems innovation; global and low-resource care
(This special issue belongs to the Section Obstetrics & Gynecology)
New Insights in Trauma and Emergency Surgery
edited by Kai Oliver Jensen and Valentin Neuhaus
submission deadline 20 Jan 2026 | Viewed by 63 | Submission Open
Keywords: trauma and emergency surgery; multiple trauma; orthopedic trauma; surgery; concepts in trauma
(This special issue belongs to the Section Emergency Medicine)
Acute Myocardial Infarction: Diagnosis, Treatment, and Rehabilitation
edited by
submission deadline 20 Jan 2026 | Viewed by 62 | Submission Open
Keywords: acute myocardial infarction; coronary angioplasty; acute heart failure; cardiogenic shock; rehabilitation programs
(This special issue belongs to the Section Cardiovascular Medicine)
Bronchoscopy and Interventional Pulmonology
edited by Bryan S. Benn and
submission deadline 20 Jan 2026 | Viewed by 61 | Submission Open
Keywords: navigation-guided bronchoscopy; Robotic-guided bronchoscopy; 3D imaging integration; lung nodule/peripheral pulmonary lesion marking; transbronchial lung cryobiopsy and interstitial lung disease; malignant and benign central airway obstruction and stenosis; airway stents; pleuroscopic procedures; bronchoscopic lung volume reduction
(This special issue belongs to the Section Respiratory Medicine)
Sarcopenia Across the Lifespan: Risk Factors, Mechanisms, and Management in Aging and Disease submission deadline 20 Jan 2026 | Viewed by 60 | Submission Open
Keywords: sarcopenia; aging; chronic disease; risk factors; muscle physiology; prevention; nutrition; exercise; treatment strategies
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Prenatal Diagnosis and Fetal Therapy
edited by
submission deadline 20 Jan 2026 | Viewed by 58 | Submission Open
Keywords: prenatal diagnosis; fetal therapy; genetic screening; non-invasive testing; fetal surgery; imaging technologies; high-risk pregnancies; in utero treatments; stem cell therapies; clinical innovations
(This special issue belongs to the Section Obstetrics & Gynecology)
Cardiac and Pulmonary Involvements in High-Risk Neonatal Cohorts: Short- and Long-Term Issues
edited by Arvind Sehgal
submission deadline 20 Jan 2026 | Viewed by 57 | Submission Open
Keywords: fetal growth restriction; lung disease; cardiac maladaptation; placenta; public health; neurodevelopment; long term; adulthood; Barker’ s hypothesis; newborn; vascular
(This special issue belongs to the Section Clinical Pediatrics)
Emerging Trends in Multiple Myeloma
edited by
submission deadline 20 Jan 2026 | Viewed by 51 | Submission Open
Keywords: multiple myeloma; personalized medicine; high-risk disease; cellular therapies; refractory disease
(This special issue belongs to the Section Hematology)
Glaucoma Surgery: Current Challenges and Future Perspectives submission deadline 20 Jan 2026 | Viewed by 49 | Submission Open
Keywords: glaucoma; filtration surgery; trabeculectomy; MIGS; scarring; anti-metabolites; wound healing; anti-fibrotics
(This special issue belongs to the Section Ophthalmology)
Current Status and Future of Urological Surgery
edited by , Davide De Marchi and
submission deadline 20 Jan 2026 | Viewed by 46 | Submission Open
Keywords: urological surgery; robotic-assisted surgery; minimally invasive surgery; artificial intelligence; augmented reality; surgical navigation; endourology; laparoscopic urology; reconstructive urology; functional urology; bph treatment; urinary incontinence; prostate cancer surgery; bladder cancer surgery; surgical innovation; digital surgery
(This special issue belongs to the Section Nephrology & Urology)
Insights and Innovations in Sports Cardiology submission deadline 20 Jan 2026 | Viewed by 43 | Submission Open
Keywords: sports cardiology; athlete heart; cardiovascular screening; arrhythmias; sudden cardiac death; cardiac rehabilitation; exercise prescription; mobile health; preventive cardiology; personalized medicine; pediatric fitness
(This special issue belongs to the Section Sports Medicine)
Therapeutic Strategies for Obesity and Diabetes in Cardiovascular Disease Patients
edited by Davide D'Andrea
submission deadline 20 Jan 2026 | Viewed by 43 | Submission Open
Keywords: obesity; diabetes; cardiovascular complications; diabetes management; pharmacological treatment; bariatric surgery; regular monitoring
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Update on Aortic Valve Disease Treatments
edited by
submission deadline 20 Jan 2026 | Viewed by 42 | Submission Open
Keywords: aortic valve disease; minimally invasive surgery; transcatheter procedures; echocardiography; diagnosis; therapy; innovation
(This special issue belongs to the Section Cardiology)
The Association Between Cancer and Cardiovascular Diseases: Insights After a Quarter of the Century
edited by Tomer Ziv-Baran and Elena Izkhakov
submission deadline 20 Jan 2026 | Viewed by 42 | Submission Open
Keywords: cancer survivors; cardiovascular disease; cardio-oncology; chemotherapy; radiation therapy; immunotherapy; multidisciplinary approach
(This special issue belongs to the Section Epidemiology & Public Health)
Rehabilitation and Treatment of Post-COVID-19 Condition submission deadline 20 Jan 2026 | Viewed by 42 | Submission Open
Keywords: post-COVID-19 condition; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); comorbidities; interdisciplinary; multimodal; digital medicine; rehabilitation; treatment; health-related quality of life; disability; return to work
(This special issue belongs to the Section Clinical Rehabilitation)
Lung Transplantation: Current Challenges and New Perspectives
edited by Reinaldo E. Rampolla and Pedro A. Catarino
submission deadline 20 Jan 2026 | Viewed by 42 | Submission Open
Keywords: lung transplantation; interstitial lung diseases; pulmonary hypertension; chronic obstructive pulmonary disease; bronchiectasis; extra corporeal membrane oxygenation; robotic lung transplantation
(This special issue belongs to the Section Respiratory Medicine)
Recent Advances and Future Perspectives of Subarachnoid Hemorrhage
edited by Alexandros Doukas and Athanasios K. Petridis
submission deadline 20 Jan 2026 | Viewed by 41 | Submission Open
Keywords: subarachnoid hemorrhage; neuromonitoring; neurocritical care; neurointerventions; neurointensive care
(This special issue belongs to the Section Clinical Neurology)
Recent Management of Hip Fractures
edited by
submission deadline 20 Jan 2026 | Viewed by 41 | Submission Open
Keywords: hip fracture; internal fixation; hemiarthroplasty; arthroplasty and fixation; osteoporosis management; fracture prevention; multidisciplinary care; surgical treatment; rehabilitation strategies
(This special issue belongs to the Section Orthopedics)
Advances in Chronic Pain Research and Therapy
edited by Elena Makovac
submission deadline 20 Jan 2026 | Viewed by 38 | Submission Open
Keywords: chronic pain; pain perception; brain-body interactions; therapeutic effectiveness; integrated approach
(This special issue belongs to the Section Clinical Rehabilitation)
Aortic Valve Disease: Current Evolution and Future Opportunities
edited by Gianluigi Perri
submission deadline 20 Jan 2026 | Viewed by 37 | Submission Open
Keywords: aortic valve disease; aortic valve repair; Ross procedure; aortic valve replacement; diagnosis of aortic valve disease
(This special issue belongs to the Section Cardiology)
Clinical Application of Echocardiography in Heart Disease: 2nd Edition
edited by
submission deadline 20 Jan 2026 | Viewed by 36 | Submission Open
Keywords: transthoracic echocardiography; transesophageal echocardiography; stress echocardiography; valve disease; coronary artery disease; myocardial disease; pericardial disease; aortic disease; congenital heart disease
(This special issue belongs to the Section Cardiology)
From Dual Diagnosis to Dual Disorder(s): Bridging Comorbidity and Integrated Clinical Understanding submission deadline 20 Jan 2026 | Viewed by 34 | Submission Open
Keywords: dual diagnosis; dual disorder; psychiatric comorbidity; addiction; integrated care; self-medication; substance use; mental illness; treatment models
(This special issue belongs to the Section Mental Health)
New Clinical Perception of Cardiac Rehabilitation
edited by and Mario Pacileo
submission deadline 20 Jan 2026 | Viewed by 34 | Submission Open
Keywords: cardiac rehabilitation; digital health; exercise therapy; cardiovascular prevention; chronic disease management; psychosocial support; personalized medicine
(This special issue belongs to the Section Clinical Rehabilitation)
Emerging Treatment Options in Inflammatory Bowel Disease
edited by and Roberta Maselli
submission deadline 20 Jan 2026 | Viewed by 30 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; biologics; small molecule therapies; personalized medicine; therapeutic drug monitoring; immunology; gut microbiome; clinical practice; endoscopic mucosal resection (EMR); endoscopic submucosal dissection (ESD); endoscopic balloon dilation and endoscopic stent placement; chromoendoscopy; confocal laser endomicroscopy; artificial intelligence
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Surgical Management of Vascular Diseases: Challenges and Innovations in the 21st Century
edited by Reinhardt T. Grundmann
submission deadline 20 Jan 2026 | Viewed by 29 | Submission Open
Keywords: abdominal aortic aneurysm; carotid stenosis; peripheral vascular disease; endovascular therapy; open surgery; vascular disease and cancer outcomes; clinical trial; meta-analysis; surgical innovation
(This special issue belongs to the Section Cardiovascular Medicine)
Pulmonary Disease and Comorbidities, Clinical and Epidemiological Studies: From Neonates to Adults
edited by
submission deadline 20 Jan 2026 | Viewed by 29 | Submission Open
Keywords: pulmonary disorders; comorbidity; neonatal lung disease; pediatric pulmonology; adult respiratory disease; chronic respiratory conditions; clinical epidemiology; pulmonary function testing; diagnostic imaging; lung biomarkers; risk factors
(This special issue belongs to the Section Respiratory Medicine)
Regional Anesthesia in Pain Management
edited by Jaime L. Baratta
submission deadline 20 Jan 2026 | Viewed by 29 | Submission Open
Keywords: acute pain; perioperative medicine; general anesthesiology; regional anesthesia; orthopedic anesthesia; multimodal analgesia
(This special issue belongs to the Section Anesthesiology)
Clinical Advances, Opportunities, and Challenges in Digestive Diseases of the Foregut
edited by Valentin Mocanu and
submission deadline 20 Jan 2026 | Viewed by 28 | Submission Open
Keywords: obesity; achalasia; reflux; malrotation; therapeutic endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Obesity-Related Metabolic and Cardiovascular Disorders
edited by and Federica Vinciguerra
submission deadline 20 Jan 2026 | Viewed by 20 | Submission Open
Keywords: obesity; type 2 diabetes mellitus; insulin resistance; metabolic syndrome; cardiovascular disease; lipid disorder; adipose tissue dysfunction; visceral adiposity; cardiometabolic risk; endothelial dysfunction; health disparities; gut microbiota; bariatric surgery; precision medicine
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances in Urologic Oncology: 2nd Edition
edited by Saum Ghodoussipour
submission deadline 20 Jan 2026 | Viewed by 17 | Submission Open
Keywords: bladder cancer; kidney cancer; prostate cancer; testis cancer; penile cancer; minimally invasive; cancer treatment
(This special issue belongs to the Section Nephrology & Urology)
Cardiometabolic Insights into Metabolic Dysfunction: From Mechanisms to Therapeutic Strategies
edited by Alessandro Andreis, and
submission deadline 20 Jan 2026 | Viewed by 13 | Submission Open
Keywords: cardiovascular complications; pharmacological; interventional strategies; cardiology; endocrinology; hepatology
(This special issue belongs to the Section Cardiology)
Macular Diseases: From Diagnosis to Treatment
edited by
submission deadline 22 Jan 2026 | Viewed by 37 | Submission Open
Keywords: age-related macular degeneration; retinal vascular diseases; intraocular tumours; retinal imaging; OCT; OCT angiography; anti-VEGF; laser therapy; macular surgery; gene therapy; biomarkers; progression; intravitreal injections; biomarkers
(This special issue belongs to the Section Ophthalmology)
Personalized Radiological and Surgical Strategies for Breast Cancer Treatment
edited by Vlad Alexandru Gata, Maximilian Muntean and
submission deadline 22 Jan 2026 | Viewed by 10 | Submission Open
Keywords: breast cancer; targeted and immune therapies; predictive biomarkers; surgical de-escalation; MRI of the breast; breast reconstruction
(This special issue belongs to the Section General Surgery)
Clinical Advances and New Challenges in Laparoscopic Surgery
edited by Ionut Bogdan Diaconescu and Matei Bratu
submission deadline 23 Jan 2026 | Submission Open
Keywords: laparoscopic surgery; trauma surgery; surgical oncology; abdominal surgery; colorectal surgery; general surgery; minimally invasive surgery; gastrointestinal surgery; hernia surgery; surgery; advance laparoscopic surgery; cancer surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates on Cardiac and Vascular Toxicities from Antineoplastic Drugs and Beyond
edited by
submission deadline 25 Jan 2026 | 5 articles | Viewed by 9408 | Submission Open
Keywords: cardiotoxicity; vascular toxicity; cardio-oncology; immune checkpoint inhibitors; anthracyclines; tyrosine kinase inhibitors; HER2; proteasome inhibitors; platinum; antimetabolites; microtubule inhibitors
(This special issue belongs to the Section Cardiovascular Medicine)
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