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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Approaches in Cataract and Refractive Surgery

edited by Stephen T. Armenti

submission deadline 20 May 2026 | Viewed by 147 | Submission Open

Keywords: cataract surgery; complex cataract surgery; secondary intraocular lens surgery; refractive surgery (LASIK; PRK; SMILE); astigmatism correction; multifocal intraocular lenses; femtosecond laser; dropless cataract surgery

(This special issue belongs to the Section Ophthalmology)

Clinical Management and Long-Term Prognosis in Intensive Care

edited by

Wioletta Mędrzycka-Dąbrowska

and

Sandra Lange

submission deadline 20 May 2026 | Viewed by 112 | Submission Open

Keywords: intensive care; post-intensive care syndrome; patient safety; improved survival; mental health; mechanical ventilation

(This special issue belongs to the Section Intensive Care)

Cutting Edge Research on Total Knee Arthroplasty

edited by

Nahum Rosenberg

submission deadline 20 May 2026 | 1 articles | Viewed by 112 | Submission Open

Keywords: total knee arthroplasty; robotic-assisted surgery; computer-navigated arthroplasty; implant design; kinematic alignment; enhanced recovery pathways; patient-reported outcomes; artificial intelligence in orthopedics; revision surgery

(This special issue belongs to the Section Orthopedics)

Artificial Intelligence in Exercise, Rehabilitation and Health Promotion: A Clinical Perspective

edited by

Ki-Hyuk Lee

and

Koji Koyama

submission deadline 20 May 2026 | Viewed by 109 | Submission Open

Keywords: artificial intelligence; machine learning and deep learning; large language models (LLMs); explainable AI; exercise and physical activity; rehabilitation and sports medicine; clinical applications; chronic disease and preventive health; digital health and big data analytics

(This special issue belongs to the Section Sports Medicine)

Spine Surgery: Current Challenges and Opportunities

edited by Kambiz Sarahrudi

submission deadline 20 May 2026 | Viewed by 91 | Submission Open

Keywords: vertebral fracture; spine trauma; spinal cord injury; adjacent segment degeneration; infection; spondylodiscitis; verte-bral metastasis; osteoporotic fracture; fracture of sacrum; disk degeneration; degenerative spine surgery; minimally invasive spine surgery

(This special issue belongs to the Section Orthopedics)

Clinical Challenges in Pancreatitis Management

edited by

Yusuke Tando

submission deadline 20 May 2026 | Viewed by 74 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; medical management; surgical management; nutritional support; pancreatic diabetes; clinical research; reviews

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Challenges in Oral and Maxillofacial Surgery

edited by

Federica Canfora

and Lucia Memé

submission deadline 20 May 2026 | Viewed by 70 | Submission Open

Keywords: oral and maxillofacial surgery; surgical management; virtual surgical planning; postoperative management; orthog-nathic surgery; reconstructive techniques; minimally invasive surgery; digital technologies; 3D printing

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Minimally Invasive Otolaryngology: Precision Techniques and Functional Outcomes

edited by Giovanni Colombo and

Matteo Di Bari

submission deadline 20 May 2026 | Viewed by 70 | Submission Open

Keywords: advances in otolaryngology; endoscopic surgery; head and neck surgery; functional outcomes; quality of life

(This special issue belongs to the Section Otolaryngology)

Physiotherapy in Clinical Practice: From Assessment to Rehabilitation

edited by

Inés Llamas Ramos

and

Rocío Llamas-Ramos

submission deadline 20 May 2026 | Viewed by 69 | Submission Open

Keywords: clinical assessment; rehabilitation; clinical practice; patient-centered care; physiotherapy innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Diagnosis and Management of Obstructive Sleep Apnea Syndrome

edited by

Graziano Montaruli

Domenico Ciavarella

and

Michele Tepedino

submission deadline 20 May 2026 | Viewed by 63 | Submission Open

Keywords: obstructive sleep apnea (OSA); apnea-hypopnea index (AHI); oxygen desaturation index (ODI); mandibular advancement device (MAD); polysomnography; upper airway; continuous positive airway pressure (C-PAP)

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Demyelinating and Neuroinflammatory Disorders

edited by

Julían Benito-Léon

submission deadline 20 May 2026 | Viewed by 62 | Submission Open

Keywords: multiple sclerosis; neuromyelitis optica spectrum disorder; MOG antibody– associated disease; neuroinflammation; biomarkers; advanced imaging; disease-modifying therapies; clinical outcomes

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Hemodialysis: 2nd Edition

edited by Maurizio Bossola

submission deadline 20 May 2026 | Viewed by 62 | Submission Open

Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy

(This special issue belongs to the Section Nephrology & Urology)

Neurovascular Interventions: Evolving Techniques and Insights

edited by Delia Cannizzaro

submission deadline 20 May 2026 | Viewed by 60 | Submission Open

Keywords: endovascular treatment; intracranial aneurysms; AI in neurointerventional surgery; intracranial vascular malformation; new endovascular device

(This special issue belongs to the Section Clinical Neurology)

Advances in Clinical Rheumatology—2nd Edition

edited by

Jacopo Ciaffi

submission deadline 20 May 2026 | Viewed by 60 | Submission Open

Keywords: rheumatoid arthritis; spondylarthritis; interventional; osteoporosis; complex regional pain syndrome

(This special issue belongs to the Section Immunology & Rheumatology)

Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies

edited by Carla Contaldi

submission deadline 20 May 2026 | Viewed by 59 | Submission Open

Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification

(This special issue belongs to the Section Cardiology)

Acute Coronary Syndromes | Circulation Research

edited by

Leslie Marisol Lugo Gavidia

and

Roberto Pedrinelli

submission deadline 20 May 2026 | Viewed by 59 | Submission Open

Keywords: acute coronary syndromes; cardiovascular risk; individualized therapy; STEMI; risk factors

(This special issue belongs to the Section Cardiology)

Clinical Progress in Oral and Maxillofacial Surgery

edited by Luis M. Junquera and Giuseppe Consorti

submission deadline 20 May 2026 | Viewed by 58 | Submission Open

Keywords: oral and maxillofacial surgery; craniofacial surgery; facial deformity; cleft lip and palate; TMJ surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Diagnosis and Treatment of Connective Tissue Diseases: A Clinician's Perspective: 2nd Edition

edited by

Agnieszka Żebrowska

Adam Reich

and Aleksandra Dańczak-Pazdrowska

submission deadline 20 May 2026 | Viewed by 58 | Submission Open

Keywords: connective tissue diseases; lupus erythematosus; scleroderma; dermatomyositis; MCTD; clinical picture; spectrum of clinical symptoms; treatment; complications; clinical follow-up

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Perspectives on Obesity and Bariatric Surgery: Outcomes and Complications

edited by Dilhana S. Badurdeen

submission deadline 20 May 2026 | Viewed by 56 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; Roux-en-Y Gastric Bypass (RYGB); sleeve gastrectomy; revisional bariatric surgery; complications; outcomes; weight loss maintenance; metabolic syndrome; type 2 diabetes remission; nutritional deficiencies; gastrointestinal adaptation; quality of life; long-term follow-up

(This special issue belongs to the Section General Surgery)

Presbyopia, Laser, Cataract and Refractive Surgery: State-of-the-Art Research: Second Edition

edited by

Ivo Guber

submission deadline 20 May 2026 | Viewed by 55 | Submission Open

Keywords: presbyopia; cataract surgery; refractive surgery; femtosecond laser; intraocular lenses; corneal refractive procedures; phakic intraocular lenses; visual outcomes; patient-reported outcomes; surgical innovations

(This special issue belongs to the Section Ophthalmology)

Strategies in Complex Hand Trauma: Bridging Orthopedics, Plastic Surgery and Rehabilitation

edited by Clarisa Simón-Pérez and

Pedro Hernandez-Cortes

submission deadline 20 May 2026 | Viewed by 53 | Submission Open

Keywords: complex hand trauma; orthopedics; plastic surgery; microsurgery; rehabilitation; functional reconstruction; multidis-ciplinary management

(This special issue belongs to the Section General Surgery)

Anesthesia in Head and Neck Surgery

edited by

Luigi V. La Via

and Antonino Maniaci

submission deadline 20 May 2026 | Viewed by 53 | Submission Open

Keywords: airway management; hemodynamic stability; perioperative monitoring; head and neck surgery; anesthesia

(This special issue belongs to the Section Anesthesiology)

Clinical Updates on Perioperative Pain Management: 3rd Edition

edited by

Felice Eugenio Agro

Giuseppe Pascarella

and

Fabio Costa

submission deadline 20 May 2026 | Viewed by 52 | Submission Open

Keywords: anesthesia and intensive care; pain management; spinal anesthesia; postoperative pain; breast surgery; fascial plane blocks; abdominal surgery; cardiac surgery; thoracotomy; knee surgery; orthopedic surgery; hip surgery; ultrasound

(This special issue belongs to the Section Anesthesiology)

Alcohol-Associated Liver Disease: Diagnosis and Treatment of Acute and Chronic Conditions

edited by Halina Cichoz-Lach and

Beata Kasztelan-Szczerbińska

submission deadline 20 May 2026 | Viewed by 52 | Submission Open

Keywords: alcohol-associated liver disease; alcohol-associated hepatitis; alcohol-associated liver cirrhosis; excessive alcohol intake; oxidative liver damage; gut– liver axis; organ-to-organ crosstalk

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Acute Medical Threats: Evidence-Driven Strategies in Emergency Medicine

edited by

Alexandra Arvanitaki

submission deadline 20 May 2026 | Viewed by 49 | Submission Open

Keywords: emergency medicine protocols; acute medical care; trauma management; resuscitation; critical care; infectious disease preparedness

(This special issue belongs to the Section Emergency Medicine)

Clinical Advances in Ocular Surgeries: Innovations in Cataract, Retinal, and Beyond

edited by

Seung Pil Bang

and Yu Cheol Kim

submission deadline 20 May 2026 | Viewed by 49 | Submission Open

Keywords: cataract surgery; retinal surgery; intraocular lenses; femtosecond laser; minimally invasive vitrectomy; ocular imaging; surgical innovation; ocular trauma; corneal transplantation; glaucoma surgery

(This special issue belongs to the Section Ophthalmology)

Clinical Research Progress in Atrial Fibrillation

edited by

Roddy Hiram

submission deadline 20 May 2026 | Viewed by 49 | Submission Open

Keywords: atrial fibrillation; atrial arrhythmias; cardiac fibrosis; inflammation; electrical remodeling

(This special issue belongs to the Section Cardiology)

Myocardial Infarction: Current Status and Future Challenges—2nd Edition

edited by Isaac Pascual and

Rebeca Lorca

submission deadline 20 May 2026 | Viewed by 48 | Submission Open

Keywords: myocardial infarction; acute coronary syndrome (ACS); ischemic heart disease; coronary artery disease (CAD); percutaneous coronary intervention; pharmacological therapy; cardiovascular risk factors

(This special issue belongs to the Section Cardiology)

The Current Trend in the Management of Bruxism and Temporomandibular Disorders, 2nd Edition

edited by

Luís Eduardo Almeida

submission deadline 20 May 2026 | Viewed by 48 | Submission Open

Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

The Application of Mechanical Circulatory Support Within Cardiology Practice

edited by

Takami Yoshiyuki

submission deadline 20 May 2026 | Viewed by 46 | Submission Open

Keywords: mechanical circulatory support (MCS); cardiogenic shock; intra-aortic balloon pumping (IABP); extracorporeal membranous oxygenation (ECMO); Impella; ventricular assist device (VAD)

(This special issue belongs to the Section Cardiology)

Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition

edited by Hendrik Kohlhof

submission deadline 20 May 2026 | Viewed by 46 | Submission Open

Keywords: knee and hip replacements; joint replacement; biomechanics; revision arthroplasty; orthogeriatrics and perioperative management

(This special issue belongs to the Section Orthopedics)

Clinical Trends and Prospects in Urology Surgery: 2nd Edition

edited by

Lazaros Tzelves

submission deadline 20 May 2026 | Viewed by 45 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; endourology; minimally invasive surgery; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Prevention, Treatment, and Prognosis of Cerebral Aneurysms

edited by Murai Yasuo

submission deadline 20 May 2026 | Viewed by 44 | Submission Open

Keywords: cerebral aneurysm; subarachnoid hemorrhage; clipping; interventional surgery; mortarity; long-term; surgical com-plication; bypass

(This special issue belongs to the Section Clinical Neurology)

Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition

edited by

Elad Asher

submission deadline 20 May 2026 | Viewed by 44 | Submission Open

Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Aspects of Return to Sport After Injuries: 2nd Edition

edited by

Anna Mika

and

Łukasz Oleksy

submission deadline 20 May 2026 | Viewed by 42 | Submission Open

Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine

(This special issue belongs to the Section Sports Medicine)

Spine Surgery and Rehabilitation: Technical Nuances and Outcomes

edited by Sehan Park and Dong-Ho Lee

submission deadline 20 May 2026 | Viewed by 42 | Submission Open

Keywords: spine surgery; rehabilitation; postoperative outcomes; surgical techniques; patient centered perspective

(This special issue belongs to the Section Orthopedics)

Advances in Diagnosis and Management of Scoliosis

edited by

Peter G. Passias

submission deadline 20 May 2026 | Viewed by 40 | Submission Open

Keywords: scoliosis; spinal deformities; therapeutic strategies; personalized care; quality of life

(This special issue belongs to the Section Orthopedics)

Transcatheter Aortic Valve Implantation and Replacement: Prospects and Challenges—2nd Edition

edited by Konstantinos Toutouzas and

Panayotis Vlachakis

submission deadline 20 May 2026 | Viewed by 37 | Submission Open

Keywords: TAVI; aortic stenosis; valve-in-valve; structural heart disease; TAVI-in-TAVI

(This special issue belongs to the Section Cardiology)

Contemporary Advances in Joint Arthroplasty: Optimizing Outcomes and Expanding Indications

edited by

Ashim Gupta

and

Hugo C. Rodriguez

submission deadline 20 May 2026 | Viewed by 36 | Submission Open

Keywords: joint arthroplasty; total joint replacement; revision arthroplasty; robotic-assisted surgery; periprosthetic joint infection (PJI); enhanced recovery after surgery (ERAS); machine learning; artifical intelligence

(This special issue belongs to the Section Orthopedics)

Valvular Heart Disease: Current Knowledge and Therapeutic Prospects

edited by Simona Mega

submission deadline 20 May 2026 | Viewed by 35 | Submission Open

Keywords: valvular heart disease; echocardiographic assessment; cardiovascular imaging; valvular regurgitation; valvular stenosis; structural heart intervention; minimally invasive cardiac surgery; catheter-based interventions

(This special issue belongs to the Section Cardiology)

Clinical Challenges in Uterus Transplant Management

edited by Giuliano Testa

submission deadline 20 May 2026 | Viewed by 34 | Submission Open

Keywords: uterus transplant; absolute uterine infertility; fertility treatment; immunosuppression in uterus transplant; pregnancy complications; uterine donor evaluation

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease

edited by Josuel Ora

submission deadline 20 May 2026 | Viewed by 32 | Submission Open

Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities

(This special issue belongs to the Section Respiratory Medicine)

Neurological Surgery: Clinical Advances and AI-Driven Innovations

edited by Ali A. Alattar

submission deadline 20 May 2026 | Viewed by 31 | Submission Open

Keywords: neurosurgery; artificial intelligence; machine learning; deep learning; radiomics; image segmentation; surgical video analytics; navigation and robotics; predictive modeling; clinical decision support

(This special issue belongs to the Section Clinical Neurology)

Bladder Cancer: Diagnosis, Treatment and Future Opportunities

edited by

Jørgen Bjerggaard Jensen

submission deadline 20 May 2026 | Viewed by 26 | Submission Open

Keywords: urology; bladder cancer; urothelial cancer; non-muscle invasive bladder cancer; muscle invasive bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

Foot and Ankle Surgery: Clinical Challenges and New Insights: 2nd Edition

edited by

Byung-Ki Cho

submission deadline 20 May 2026 | Viewed by 22 | Submission Open

Keywords: hallux valgus; minimal invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis

(This special issue belongs to the Section Orthopedics)

The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications

edited by

Jonathan Guez

and

Rotem Saar

submission deadline 20 May 2026 | Viewed by 21 | Submission Open

Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications

(This special issue belongs to the Section Mental Health)

Audiology and Phoniatrics in Head and Neck Surgery: Functional Assessment, Rehabilitation Strategies, and Quality of Life Outcomes

edited by

Claudia Cassandro

submission deadline 20 May 2026 | Viewed by 16 | Submission Open

Keywords: audiology; phoniatrics; voice disorders; hearing preservation; speech rehabilitation; head and neck surgery; functional outcomes; quality of life; voice analysis; audiometry; cochlear implants; dysphagia; laryngeal surgery

(This special issue belongs to the Section Otolaryngology)

Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)

edited by

Orestis Ioannidis

submission deadline 25 May 2026 | 4 articles | Viewed by 7804 | Submission Open

Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative

(This special issue belongs to the Section General Surgery)

Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition

edited by

Giulio Maurizi

submission deadline 25 May 2026 | 1 articles | Viewed by 5113 | Submission Open

Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer

(This special issue belongs to the Section Respiratory Medicine)

Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies

edited by

Kamil Nelke

Maciej Dobrzyński

and

Michał Gontarz

submission deadline 25 May 2026 | 1 articles | Viewed by 725 | Submission Open

Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 1301-1350 on page 27 of 31.

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