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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Geriatric Cardiology: Clinical Advances and Comprehensive Management
edited by
submission deadline 25 Jun 2026 | Viewed by 37 | Submission Open
Keywords: geriatric assessment; management of cardiovascular disease; cardiovascular health; geriatric cardiology; frailty evaluation and management
(This special issue belongs to the Section Geriatric Medicine)
Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Current Concepts and Clinical Implications
edited by
submission deadline 25 Jun 2026 | Viewed by 35 | Submission Open
Keywords: myopic optic neuropathy; glaucomatous optic neuropathy; tilting; axonal transport; lamina cribrosa
(This special issue belongs to the Section Ophthalmology)
Diagnosis and Management of Corneal Diseases
edited by Nicola Cardascia
submission deadline 25 Jun 2026 | Viewed by 32 | Submission Open
Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation
(This special issue belongs to the Section Ophthalmology)
Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition submission deadline 25 Jun 2026 | Viewed by 32 | Submission Open
Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure
(This special issue belongs to the Section Cardiology)
Advances in Minimally Invasive and Endoscopic Neurosurgery
edited by Shunsuke Shibao
submission deadline 25 Jun 2026 | Viewed by 31 | Submission Open
Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery
(This special issue belongs to the Section Clinical Neurology)
Oral Health and Systemic Diseases: Clinical Insights
edited by
submission deadline 25 Jun 2026 | Viewed by 29 | Submission Open
Keywords: oral health; endodontics; orthodontic; periodontal disease; dental caries
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in Immunohematology: From Pathophysiology to Tailored Treatments submission deadline 25 Jun 2026 | Viewed by 22 | Submission Open
Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination
(This special issue belongs to the Section Immunology & Rheumatology)
Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition submission deadline 25 Jun 2026 | Viewed by 19 | Submission Open
Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives
edited by Shintaro Chiba
submission deadline 25 Jun 2026 | Viewed by 19 | Submission Open
Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology
(This special issue belongs to the Section Respiratory Medicine)
Cystic Fibrosis: Management Strategies and Patient Outcomes
edited by Marta Rachel
submission deadline 25 Jun 2026 | Viewed by 19 | Submission Open
Keywords: cystic fibrosis; multidisciplinary care; personalized medicine; patient outcomes; telemedicine; pediatric pulmonology; CFTR modulators; chronic disease management
(This special issue belongs to the Section Respiratory Medicine)
Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies submission deadline 25 Jun 2026 | Viewed by 16 | Submission Open
Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities
(This special issue belongs to the Section Epidemiology & Public Health)
Clinical Management of Traumatic Brain Injury
edited by Adam James Wells and Peter Hutchinson
submission deadline 25 Jun 2026 | Viewed by 14 | Submission Open
Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence
(This special issue belongs to the Section Clinical Neurology)
Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases
edited by
submission deadline 25 Jun 2026 | Viewed by 13 | Submission Open
Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in General and Regional Anaesthesia
edited by Michał Jan Stasiowski, and
submission deadline 26 Jun 2026 | Viewed by 25 | Submission Open
Keywords: general anaesthesia; regional anaesthesia; ropivacaine; bupivacaine; postoperative pain; postoperative nausea and vomiting; preventive analgesia; rescue opioid analgesia; total intravenous anaesthesia; inhalational anaesthesia
(This special issue belongs to the Section Anesthesiology)
Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management submission deadline 30 Jun 2026 | Viewed by 33 | Submission Open
Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics
(This special issue belongs to the Section Orthopedics)
Integrating a One Health Approach into Antimicrobial Stewardship and Shared Care in Wound Management
edited by Joanna F. Blackburn
submission deadline 30 Jun 2026 | Viewed by 32 | Submission Open
Keywords: antimicrobial stewardship; antimicrobial resistance; one health; shared care; wound care; wound care management; chronic wound care; acute wound care; digital health; wound diagnostics; antimicrobials; antibiotics
(This special issue belongs to the Section Dermatology)
Clinical Advances in Aortic Disease and Revascularization: 2nd Edition
edited by Andrej Udelnow
submission deadline 30 Jun 2026 | Viewed by 21 | Submission Open
Keywords: aortic disease; aortic aneurysm; endovascular aortic repair; atherosclerosis; aortic dissections; overall survival; quality of life; intravascular ultrasound
(This special issue belongs to the Section Vascular Medicine)
Modern Challenges in Pediatric Endocrinology: From Growth Disorders to Metabolic Dysregulation
edited by Katarzyna A. Majewska and Piotr Fichna
submission deadline 2 Jul 2026 | Viewed by 5 | Submission Open
Keywords: growth hormone deficiency; growth hormone therapy; short stature; obesity; obesity complications; obesity treatment; insulin resistance; prediabetes; type 1 diabetes; type 2 diabetes; hypothyroidism; hyperthyroidism; autoimmune thyroiditis; puberty disorders
(This special issue belongs to the Section Clinical Pediatrics)
Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside submission deadline 10 Jul 2026 | Viewed by 35 | Submission Open
Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers
(This special issue belongs to the Section Respiratory Medicine)
Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics
edited by Dafni Charisopoulou and
submission deadline 10 Jul 2026 | Viewed by 23 | Submission Open
Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure
(This special issue belongs to the Section Cardiology)
Endoscopic Therapy in Gastroesophageal Reflux Disease (GERD): Current Evidence, Techniques, and Future Perspectives
edited by Pier Alberto Testoni
submission deadline 10 Jul 2026 | Viewed by 19 | Submission Open
Keywords: gastroenterology; gastroesophageal reflux disease; GERD; esophageal diseases; endoscopic therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery
edited by , RareÈ™ Calin Roman and Mihaela Carmen HedeÅŸiu
submission deadline 15 Jul 2026 | Viewed by 368 | Submission Open
Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies
edited by
submission deadline 15 Jul 2026 | Viewed by 30 | Submission Open
Keywords: infertility; assisted reproductive technologies (ARTs); ovarian reserve; antral follicle count (AFC); anti-mullerian hormone (AMH); fertility preservation; IVF pregnancy; ovarian stimulation; embryo selection
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Approaches to Prevention and Management of Postoperative Complications in Minimally Invasive Surgery
edited by Shingo Tsujinaka
submission deadline 15 Jul 2026 | Viewed by 25 | Submission Open
Keywords: minimally invasive surgery; postoperative complications; preventive measures; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes
(This special issue belongs to the Section General Surgery)
Aortic Dissection: Current Trends, Complexities, and Future Directions
edited by Aung Ye Oo
submission deadline 15 Jul 2026 | Viewed by 23 | Submission Open
Keywords: aortic dissection; aortic surgery; hybrid and endovascular repair; diagnostic delay; systems of care; patient safety; biomarkers and imaging; postoperative outcomes; multidisciplinary collaboration in aortic disease management
(This special issue belongs to the Section Cardiovascular Medicine)
Current Challenges and Advancements in Stroke Prevention and Cerebrovascular Disorders
edited by and Sylwia Krzemińska
submission deadline 15 Jul 2026 | Viewed by 19 | Submission Open
Keywords: risk factors; secondary prevention; health education; health behaviors
(This special issue belongs to the Section Clinical Rehabilitation)
Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment submission deadline 15 Jul 2026 | Viewed by 19 | Submission Open
Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment
(This special issue belongs to the Section Orthopedics)
Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options
edited by Przemysław Puz, and
submission deadline 15 Jul 2026 | Viewed by 10 | Submission Open
Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection
(This special issue belongs to the Section Clinical Neurology)
Neurosurgery Advancements: Techniques and Patient Outcomes
edited by Vianney Gilard
submission deadline 15 Jul 2026 | Viewed by 3 | Submission Open
Keywords: neurosurgery; minimally invasive surgery; endoscopic spine surgery; intraoperative imaging; neuro-oncology; functional neurosurgery; neurovascular surgery; patient outcomes
(This special issue belongs to the Section Clinical Neurology)
Current Concepts in Melanoma: Innovations in Early Detection, Prognosis and Management
edited by Babar Khan Rao
submission deadline 20 Jul 2026 | Viewed by 96 | Submission Open
Keywords: melanoma; early detection; non-invasive diagnostic innovations; artificial intelligence-assisted diagnosis; melanoma management
(This special issue belongs to the Section Dermatology)
Exercise for Healthy Aging: Clinical Physiology, Functional Outcomes, and Implications for Clinical Practice submission deadline 20 Jul 2026 | Viewed by 53 | Submission Open
Keywords: exercise; healthy aging; functional independence; mitochondrial adaptations; physical activity interventions; neuromuscular function; cardiorespiratory fitness; metabolic health; biomarkers of aging
(This special issue belongs to the Section Sports Medicine)
Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Advancing Diagnosis and Management
edited by Olga Reitblat
submission deadline 20 Jul 2026 | Viewed by 46 | Submission Open
Keywords: cataract surgery; premium intraocular lenses (IOLs); IOL power calculation; visual outcomes; refractive cataract surgery; multifocal IOL; extended depth of focus (EDOF) IOL; toric IOL; full range; vision IOL; biometry
(This special issue belongs to the Section Ophthalmology)
Clinical Implications of Artificial Intelligence in Patient Care
edited by and
submission deadline 20 Jul 2026 | Viewed by 41 | Submission Open
Keywords: artificial intelligence; clinical decision support; human factors; digital health; patient care; implementation science; medical informatics; trust in AI
(This special issue belongs to the Section Clinical Research Methods)
Clinical Updates in Fractures: Orthopedics, Trauma Surgery, and Rehabilitation
edited by
submission deadline 20 Jul 2026 | Viewed by 40 | Submission Open
Keywords: orthopedic surgery; global orthopedic health; surgical techniques; outreach; inreach; artificial intelligence; robotics; outcome measures
(This special issue belongs to the Section Orthopedics)
Advances in the Management of Cough and Asthma
edited by Ebymar Arismendi
submission deadline 20 Jul 2026 | Viewed by 32 | Submission Open
Keywords: asthma; chronic cough; biomarkers; exacerbations; biologics; precision medicine; airway inflammation; pediatric asthma
(This special issue belongs to the Section Respiratory Medicine)
Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options
edited by Antonio J. Amor and Tonet Serés-Noriega
submission deadline 20 Jul 2026 | Viewed by 29 | Submission Open
Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound
(This special issue belongs to the Section Cardiovascular Medicine)
Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives submission deadline 20 Jul 2026 | Viewed by 28 | Submission Open
Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine
(This special issue belongs to the Section Clinical Rehabilitation)
Thoracic Surgery Today: Innovations, Challenges, and Future Perspectives
edited by Jeffrey B. Velotta and
submission deadline 20 Jul 2026 | Viewed by 27 | Submission Open
Keywords: thoracic surgery; minimally invasive thoracic surgery; innovation; esophageal surgery; robotic-assisted thoracic surgery; lung cancer; advanced techniques; thoracic surgical oncology; mediastinal surgery; mesothelioma surgery
(This special issue belongs to the Section General Surgery)
Current Advances and Future Perspectives in Cardiothoracic Surgery
edited by Tomislav Kopjar
submission deadline 20 Jul 2026 | Viewed by 24 | Submission Open
Keywords: cardiothoracic surgery; minimally invasive techniques; robotic-assisted surgery; personalized therapy; surgical innovation; prosthetic devices; perioperative management; transplantation; technological advances; postoperative care; surgical outcomes; future perspectives; healthcare disparities
(This special issue belongs to the Section General Surgery)
Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease
edited by and Aleksander Dokollari
submission deadline 20 Jul 2026 | Viewed by 20 | Submission Open
Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement
(This special issue belongs to the Section Cardiology)
Current Updates on Pediatric Neurological Disorders and Neurorehabilitation submission deadline 20 Jul 2026 | Viewed by 19 | Submission Open
Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy
(This special issue belongs to the Section Clinical Pediatrics)
Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention
edited by Marco Ciardetti and Alessio Mattesini
submission deadline 20 Jul 2026 | Viewed by 17 | Submission Open
Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification
(This special issue belongs to the Section Cardiology)
State of the Art in Spinal Cord Injuries: Clinical Rehabilitation and Management
edited by
submission deadline 20 Jul 2026 | Viewed by 13 | Submission Open
Keywords: neurorehabilitation; assistive technologies; neuroplasticity; neuromodulation; spinal cord injury
(This special issue belongs to the Section Clinical Rehabilitation)
Orthodontics: Current Management and Future Options
edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė
submission deadline 20 Jul 2026 | Viewed by 12 | Submission Open
Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology submission deadline 20 Jul 2026 | Viewed by 12 | Submission Open
Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence
(This special issue belongs to the Section Cardiology)
Pre-Hospital and In-Hospital Emergency Care Research
edited by , and Yohei Okada
submission deadline 20 Jul 2026 | Viewed by 8 | Submission Open
Keywords: pre-hospital; in-hospital; emergency care; emergency medical services; acute care
(This special issue belongs to the Section Emergency Medicine)
Clinical Advances in Chronic Lymphocytic Leukemia: Focus on Elderly Frail Patients
edited by Driss Chaoui
submission deadline 20 Jul 2026 | Viewed by 5 | Submission Open
Keywords: CLL; elderly; frailty; guidelines; quality of life; IBTK; BCL2; antiCD20
(This special issue belongs to the Section Hematology)
New Perspective of Oral and Maxillo-Facial Surgery:2nd Edition
edited by , and Alessandra Lucchese
submission deadline 20 Jul 2026 | Viewed by 4 | Submission Open
Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies submission deadline 20 Jul 2026 | Viewed by 3 | Submission Open
Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound
(This special issue belongs to the Section Obstetrics & Gynecology)
Minimally Invasive Spine Surgery: Evidence, Advances and Controversies
edited by , Constantine Constantoyannis, Mark A. MacLean and Oliver Lasry
submission deadline 20 Jul 2026 | Viewed by 2 | Submission Open
Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality
(This special issue belongs to the Section Clinical Neurology)
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