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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Mar 2026 | 6 articles | Viewed by 15139 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Moving Forward to New Trends in Pulmonary Diseases

edited by

Ramona Cioboata

and

Costin Teodor Streba

submission deadline 20 Mar 2026 | 6 articles | Viewed by 13842 | Submission Open

Keywords: pulmonary tuberculosis; chronic obstructive airway diseases; bronchiectasis; COVID-19; sleep apnea; ultrasound; lung cancer; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Risk Prediction for Gynecological Cancer

edited by

Federico Ferrari

submission deadline 20 Mar 2026 | 7 articles | Viewed by 13109 | Submission Open

Keywords: cervical cancer; endometrial cancer; tubo-ovarian cancer; diagnosis; treatment; prognosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Management of Prosthetic Joint Infection (PJI)

edited by Daniel Pérez-Prieto

submission deadline 20 Mar 2026 | 7 articles | Viewed by 11332 | Submission Open

Keywords: prosthetic joint infection; debridement; biofilm; wound healing; multidisciplinary team; osteomyelitis

(This special issue belongs to the Section Orthopedics)

Chronic Kidney Disease: Clinical Challenges and Management

edited by

Shuzo Kobayashi

and

Takayasu Ohtake

submission deadline 20 Mar 2026 | 5 articles | Viewed by 9848 | Submission Open

Keywords: chronic kidney disease; clinical trial; end-stage renal disease; kidney dysfunction; management; challenge

(This special issue belongs to the Section Nephrology & Urology)

Innovation in Hand Surgery

edited by Rocco De Vitis and Marco Passiatore

submission deadline 20 Mar 2026 | 7 articles | Viewed by 9560 | Submission Open

Keywords: hand surgery; hand reconstruction; hand deformities; reconstructive surgery; peripheral nerve surgery; hand tumors; thumb arthritis; wrist arthritis; arthroscopy; prosthesis

(This special issue belongs to the Section Orthopedics)

Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation

edited by Young-Jin Seo

submission deadline 20 Mar 2026 | 6 articles | Viewed by 8942 | Submission Open

Keywords: anterior cruciate ligament (ACL); reconstruction; lateral extra-articular procedures; all-inside technique; internal bracing; slope reducing osteotomy; biologic augmentation; rehabilitation

(This special issue belongs to the Section Orthopedics)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 20 Mar 2026 | 3 articles | Viewed by 7864 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Surgical Treatment for Lung Cancer

edited by

Piotr Gabryel

, Cezary Piwkowski and Marek Ochman

submission deadline 20 Mar 2026 | 5 articles | Viewed by 7561 | Submission Open

Keywords: lung cancer; surgery; minimally invasive surgery; immunotherapy; enhanced recovery after surgery; segmentectomy

(This special issue belongs to the Section Respiratory Medicine)

New Advances in Musculoskeletal Physiotherapy: Exercise, Manual Therapy and Invasive Physiotherapy

edited by

Marcos José Navarro-Santana

and Ignacio Cancela-Cilleruelo

submission deadline 20 Mar 2026 | 5 articles | Viewed by 7537 | Submission Open

Keywords: musculoskeletal disorders; exercise therapy; manual therapy; invasive physical therapy; rehabilitation

(This special issue belongs to the Section Orthopedics)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Mar 2026 | 7 articles | Viewed by 7453 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Gastrointestinal Endoscopy: Clinical Advances in Diagnosis and Treatment, 2nd Edition

edited by Joao Santos-Antunes and

Tadateru Maehata

submission deadline 20 Mar 2026 | 2 articles | Viewed by 7147 | Submission Open

Keywords: diagnostic endoscopy; therapeutic endoscopy; gastrointestinal neoplasia; endoscopic mucosal resection; endoscopic submucosal dissection; early cancer; subepithelial lesions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Innovations in the Treatment for Depression and Anxiety

edited by Lucie Bartova

submission deadline 20 Mar 2026 | 3 articles | Viewed by 6787 | Submission Open

Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance

(This special issue belongs to the Section Mental Health)

Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future Directions

edited by

Scipione Carerj

and Fausto Pizzino

submission deadline 20 Mar 2026 | 4 articles | Viewed by 6569 | Submission Open

Keywords: echocardiographic imaging; transcatheter intervention; aortic stenosis; mitral regurgitation; tricuspid regurgitation; left atrial appendage closure; patent foramen ovale closure; atrial septal defect repair

(This special issue belongs to the Section Cardiology)

Renal Cell Carcinoma: From Diagnostic to Therapy

edited by Ithaar H. Derweesh and Zachary A. Hamilton

submission deadline 20 Mar 2026 | 4 articles | Viewed by 5953 | Submission Open

Keywords: biomarkers; clinical practice patterns; diagnosis; kidney cancer; metastasis; renal cell carcinoma; renal mass; staging; systemic therapy; surveillance

(This special issue belongs to the Section Nephrology & Urology)

Skin Disease and Inflammation

edited by

Taihao Quan

submission deadline 20 Mar 2026 | 1 articles | Viewed by 5428 | Submission Open

Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea

(This special issue belongs to the Section Dermatology)

Improving Diagnosis and Treatment of Vestibular Disorder: Latest Advances and Challenges

edited by

Enrico Armato

Andrea Castellucci

and Athanasia Korda

submission deadline 20 Mar 2026 | 2 articles | Viewed by 5105 | Submission Open

Keywords: vestibular system; balance disorders; dizziness; vertigo; vestibular testing; videonystagmography; video head impulse test; vestibular evoked myogenic potentials; vestibular rehabilitation therapy

(This special issue belongs to the Section Otolaryngology)

Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges, 2nd Edition

edited by Botond Csiky

submission deadline 20 Mar 2026 | 2 articles | Viewed by 4898 | Submission Open

Keywords: chronic kidney disease progression; cardiovascular risk factors; diabetes mellitus; obesity; kidney transplantation; survival; pathophysiology of CKD; hemodialysis; peritoneal dialysis; metabolic and mineral bone disease

(This special issue belongs to the Section Nephrology & Urology)

Advanced Therapy for Heart Failure and Other Combined Diseases

edited by Gori Mauro and Marco Marini

submission deadline 20 Mar 2026 | 5 articles | Viewed by 4829 | Submission Open

Keywords: heart failure with reduced and preserved ejection fraction; advanced heart failure; inotropes; acute heart failure; GDMT

(This special issue belongs to the Section Cardiology)

Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)

edited by

Pierluigi Carratù

submission deadline 20 Mar 2026 | 3 articles | Viewed by 4562 | Submission Open

Keywords: obstructive sleep apnea syndrome; diagnosis; obesity; treatment; CPAP; comorbidities; cardiovascular risk

(This special issue belongs to the Section Respiratory Medicine)

The Role of Scleral Lenses in the Management of Eye Disease

edited by Cherie B. Nau

submission deadline 20 Mar 2026 | 1 articles | Viewed by 4422 | Submission Open

Keywords: scleral lenses; corneal irregularity; corneal disease; dry eye disease; irregular astigmatism; keratoconus; meibomian gland dysfunction; midday fogging

(This special issue belongs to the Section Ophthalmology)

Advanced Approaches in Hip and Knee Arthroplasty

edited by Filippo Randelli and

Alberto Fioruzzi

submission deadline 20 Mar 2026 | 4 articles | Viewed by 4265 | Submission Open

Keywords: hip; hip surgery; knee arthroplasty; knee surgery; hip and knee arthroplasty

(This special issue belongs to the Section Orthopedics)

Psoriasis in Focus: Current Research, Treatments, and Future Directions

edited by

Tamara Gracia-Cazaña

and Josep Riera-Monroig

submission deadline 20 Mar 2026 | 4 articles | Viewed by 4201 | Submission Open

Keywords: psoriasis; biologic therapies; immunopathogenesis; precision medicine; comorbidities in psoriasis; psoriatic arthritis; phototherapy; topical treatments; systemic therapies

(This special issue belongs to the Section Dermatology)

Clinical and Surgical Updates on Bariatric Surgery

edited by

Claudio Gambardella

submission deadline 20 Mar 2026 | 2 articles | Viewed by 4120 | Submission Open

Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; surgical complications; diabetes remission; hypertension remission; hypercholesterolemia remission; GERD; de novo GERD

(This special issue belongs to the Section General Surgery)

Clinical Advances in Kidney Transplantation

edited by

Florin Ioan Elec

and

Oana Antal

submission deadline 20 Mar 2026 | 3 articles | Viewed by 3915 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy

edited by

Athanasios Samaras

and

Andreas S. Papazoglou

submission deadline 20 Mar 2026 | 2 articles | Viewed by 3689 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology

(This special issue belongs to the Section Cardiology)

Acute Pancreatitis and Its Complications: Current Diagnostics and Management

edited by

Beata Jabłońska

submission deadline 20 Mar 2026 | 3 articles | Viewed by 3468 | Submission Open

Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Mar 2026 | 5 articles | Viewed by 3380 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

Advances in Breast Reconstruction: New Technologies Improving Clinical Outcomes

edited by Luigi Antonio Valdatta

submission deadline 20 Mar 2026 | 3 articles | Viewed by 3086 | Submission Open

Keywords: breast reconstruction; acellular dermal matrix (ADM); artificial intelligence in surgery; advanced prostheses; breast malformation correction; 3D printing in reconstruction; robotic-assisted breast surgery; regenerative surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Challenges and Opportunities in Prenatal Diagnosis

edited by Diana Massalska and

Julia Bijok

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2919 | Submission Open

Keywords: prenatal diagnosis; genetic testing; fetal imaging; fetal therapy; personalized prenatal medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Artificial Intelligence, Computer Modeling and Technology: Clinical Changing Practice in Reconstructive Surgery

edited by

Warren Matthew Rozen

and

Ishith Seth

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2768 | Submission Open

Keywords: reconstructive surgery; plastic surgery; breast surgery; breast reconstruction; oncologic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Recent Advances in the Prevention, Treatment, and Rehabilitation of Sports Injuries

edited by Nili Steinberg

submission deadline 20 Mar 2026 | 3 articles | Viewed by 2727 | Submission Open

Keywords: athletes; physical activity; sports; injuries; musculoskeletal; pain; rehabilitation; prevention; risk factors; functional abilities; muscle strength; joint range of motion (ROM); postural balance; ultrasonography maturation; adolescent

(This special issue belongs to the Section Sports Medicine)

Management of Inflammatory Bowel Disease: A Multidisciplinary Perspective

edited by

Gary Edward Wild

and

Kimberly Carrière

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2661 | Submission Open

Keywords: inflammatory bowel disease management; Crohn's disease; ulcerative colitis; patient-centered care; multidisciplinary management; personalized treatment

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Progress in Pediatric Orthopedics and Pediatric Spine Surgery

edited by

Barbara Jasiewicz

submission deadline 20 Mar 2026 | 3 articles | Viewed by 2425 | Submission Open

Keywords: pediatric spine; scoliosis; clubfoot; flatfoot; developmental dysplasia of the hip; rare diseases

(This special issue belongs to the Section Clinical Pediatrics)

Hypertension: Clinical Treatment and Management

edited by

José L. Flores-Guerrero

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2313 | Submission Open

Keywords: hypertension management; weight control; blood pressure monitoring; wearable technology; telemonitoring sys-tems; immune therapy; resistant hypertension; lifestyle interventions; cardiovascular health; advanced treatment strate-gies

(This special issue belongs to the Section Epidemiology & Public Health)

Dual-Energy and Spectral CT in Clinical Practice: 2nd Edition

edited by

Giovanni Foti

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1968 | Submission Open

Keywords: dual-energy CT; spectral CT; photon counting CT; oncology; bone marrow edema; prosthesis; liver; pancreas; lung; kidney; adrenal; brain; abdomen; cardiac; coronary arteries; arthritis

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Implications of Pupil Function: Optical Quality, Visual Performance, and Neurological Biomarkers

edited by Pablo De Gracia and Héctor E. Soriano Baron

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1901 | Submission Open

Keywords: pupil function; visual performance; intraocular lens (IOL) optimization; pupillometry diagnostics; neuro-ophthalmic biomarkers

(This special issue belongs to the Section Ophthalmology)

Lung Transplantation: Clinical Advances and Practice Updates

edited by Milton Saute

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1877 | Submission Open

Keywords: lung transplantation; respiratory failure; thoracic surgery; cardiothoracic surgery; solid organ transplantation; immunosuppression; lung cancer

(This special issue belongs to the Section Respiratory Medicine)

Diagnosis and Surgical Treatment for Colorectal Cancer

edited by Nidal Issa, Wisam Khoury and Rachel Gingold-Belfer

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1758 | Submission Open

Keywords: colorectal cancer; laparoscopy; colonoscopy; colectomy; diagnosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Advances in Systemic Lupus Erythematosus (SLE)

edited by

Chang-Hee Suh

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1756 | Submission Open

Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life

(This special issue belongs to the Section Immunology & Rheumatology)

Systemic Autoimmune Disorder with Pulmonary Involvement: Novel Insights from Underlying Mechanisms of Drug Development and Intervention

edited by

Fabio Perrotta

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1637 | Submission Open

Keywords: rheumatic diseases; pulmonary involvement; connective tissue disorders; systemic autoimmune disorders (SARDs); diagnosis; innovative treatments

(This special issue belongs to the Section Respiratory Medicine)

Clinical Therapy in Dementia and Related Diseases

edited by

Takao Yamasaki

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1561 | Submission Open

Keywords: dementia; aging society; disease-modifying therapies (DMT); early diagnosis; lifestyle interventions; multimorbidity management; non-pharmacological treatments; personalized medicine; quality of life (QOL); digital health technologies

(This special issue belongs to the Section Mental Health)

Advances in Clinical Exercise for Health

edited by

Pedro Miguel Forte

and Joana Ribeiro

submission deadline 20 Mar 2026 | 3 articles | Viewed by 1517 | Submission Open

Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology

(This special issue belongs to the Section Sports Medicine)

Thrombosis and Haemostasis: Clinical Advances

edited by Hui Yin Lim

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1309 | Submission Open

Keywords: venous thrombosis; biomarkers; bleeding; direct oral anticoagulants; pulmonary embolism; factor XI inhibitors; factor XII inhibitors; endovascular treatment

(This special issue belongs to the Section Vascular Medicine)

Clinical Developments of Oral and Maxillofacial Surgery

edited by

José María Martinez-Gonzalez

and

Natalia Martínez-Rodríguez

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1304 | Submission Open

Keywords: oral surgery; maxillofacial surgery; bone resorption; implant surgery; oral rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Acute Hypoxemic Respiratory Failure: Progress, Challenges and Future

edited by

Davide Alberto Chiumello

and

Jesús Villar

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1253 | Submission Open

Keywords: ARDS; artificial intelligence; mechanical ventilation; non-invasive ventilation; lung imaging

(This special issue belongs to the Section Intensive Care)

Clinical Diagnosis and Therapeutic Approaches for Acute and Chronic Coronary Syndromes

edited by Rocco Antonio Montone

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1239 | Submission Open

Keywords: coronary artery disease; clinical diagnosis; therapeutic approaches; atherosclerosis; risk factors; percutaneous cor-onary intervention; acute coronary syndrome; MINOCA; INOCA

(This special issue belongs to the Section Cardiology)

Pancreatic Surgery: Clinical Practices and Challenges

edited by Guido Alsfasser and

Roberto Salvia

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1163 | Submission Open

Keywords: prognostic variables; surgical technique; outcome; timing of surgery; perioperative strategies; pancreatic cancer; pancreatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Perspectives in Cardiac Imaging: How to See the Unseen

edited by

Adriana D'Antonio

and Wanda Acampa

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1125 | Submission Open

Keywords: cardiac imaging; MPI; PET; SPECT; CCTA; MR; CAD; heart failure; cardiac sarcoidosis; cardiac amyloidosis; valvular disease; artificial intelligence

(This special issue belongs to the Section Cardiology)

Advances in Minimally Invasive Gynecologic Surgery: Optimizing Outcomes and Perioperative Strategies

edited by Raanan Meyer

submission deadline 20 Mar 2026 | 2 articles | Viewed by 1082 | Submission Open

Keywords: minimally invasive gynecologic surgery; MIGS; laparoscopy; robotic surgery; endometrial cancer; endometriosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 851-900 on page 18 of 31.

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