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Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future...
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Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future Directions

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 28 September 2025 | Viewed by 2910

Special Issue Editors

Prof. Dr. Scipione Carerj

E-Mail Website
Guest Editor
Department of Clinical and Experimental Medicine, Policlinic “G. Martino”, University of Messina, 98122 Messina, Italy
Interests: echocardiography; cardiomyopathies; cardiovascular; atrial fibrillation; atherosclerosis; cardiac imaging; transesophageal echocardiography; heart valve diseases; heart failure; hypertension
Dr. Fausto Pizzino

E-Mail Website
Guest Editor
Cardiology Unit, Heart Centre, Fondazione Gabriele Monasterio—Regione Toscana, 54100 Massa, Italy
Interests: clinical cardiology; advanced cardiovascular imaging; cardiac magnetic resonance; transthoracic echocardiography; transesophageal echocardiography
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Echocardiographic imaging has firmly established itself as a cornerstone in the realm of transcatheter structural interventions. This Special Issue, “Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future Directions”, seeks to illuminate the pivotal role of echocardiography in advancing patient care and procedural success in this dynamic field.

Echocardiography’s applications in transcatheter interventions are vast, encompassing the evaluation, guidance, and follow-up of procedures. Particularly, innovative approaches to the echocardiographic assessment and guidance of transcatheter treatments for valvular diseases, such as aortic stenosis, mitral regurgitation, and tricuspid regurgitation, are of great interest. Moreover, the use of echocardiography in left atrial appendage closure, patent foramen ovale closure, and atrial septal defect repair underscores its indispensable role.

We invite our esteemed colleagues to contribute review and original articles that showcase cutting-edge echocardiographic techniques and innovations. Research that focuses on novel imaging applications, the integration of advanced technologies, and solutions to current challenges in the echocardiographic evaluation and guidance of structural heart interventions is particularly welcomed.

Your contributions will not only highlight current practices but will also set the stage for future advancements in echocardiographic imaging, ensuring continued improvement in patient outcomes and procedural success.

Warm regards,

Prof. Dr. Scipione Carerj
Dr. Fausto Pizzino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • echocardiographic imaging
  • transcatheter intervention
  • aortic stenosis
  • mitral regurgitation
  • tricuspid regurgitation
  • left atrial appendage closure
  • patent foramen ovale closure
  • atrial septal defect repair

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Published Papers (2 papers)

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Research

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9 pages, 3086 KiB  
Article
Standardized 3D Transoesophageal Echocardiography Manoeuvre for Enhanced Tenting Height Evaluation During Transcatheter Mitral Valve Edge-to-Edge Repair
by Michela Bonanni, Giancarlo Trimarchi, Giovanni Benedetti, Andreina D’Agostino, Giuseppe Iuliano, Rachele Manzo, Rosangela Capasso, Elisa Cerone, Umberto Paradossi, Sergio Berti and Massimiliano Mariani
J. Clin. Med. 2024, 13(21), 6525; https://doi.org/10.3390/jcm13216525 - 30 Oct 2024
Cited by 5 | Viewed by 1792
Abstract
Background: Transcatheter treatments for structural heart disease, including edge-to-edge mitral valve repair (mTEER), heavily rely on transoesophageal echocardiography (TOE) for pre-procedural assessment and guidance. Trans-septal puncture (TSP) is one of the first key steps of such procedures, with two-dimensional (2D) TOE often providing [...] Read more.
Background: Transcatheter treatments for structural heart disease, including edge-to-edge mitral valve repair (mTEER), heavily rely on transoesophageal echocardiography (TOE) for pre-procedural assessment and guidance. Trans-septal puncture (TSP) is one of the first key steps of such procedures, with two-dimensional (2D) TOE often providing suboptimal imaging. Three-dimensional (3D) echocardiography could overcome the limitations of 2D TOE and improve the assessment of tenting height. Methods: This single-centre, retrospective study included 64 patients who underwent mTEER between October 2023 and April 2024. Tenting height during TSP was assessed by 2D TOE in mid-oesophageal (ME) four-chamber view and by 3D TOE after the acquisition of a 3D volume, including the interatrial septum, aortic valve, and mitral valve, and subsequent multiplanar reconstruction (MPR). A total of 100 TSP attempts with 2D and 3D TOE were evaluated. Results: Procedural success was obtained in 92.2% of cases. There was a statistically significant difference between 2D and 3D measurements (2D: 4.36 ± 0.61 cm, MPR: 4.59 ± 0.63 mm2, p < 0.001), despite good correlation (r = 0.880, p < 0.001). The difference between 2D and 3D tenting height measurements differed significantly between patients with optimal and suboptimal 2D image windows (p < 0.001). There was no significant difference in septal puncture success between optimal 2D and 3D data (p = 0.942). Conclusions: Adopting 3D TOE with multiplanar reconstruction for assessing tenting height in mTEER procedures offers significant advantages over traditional 2D TOE. Enhanced visualization, accuracy, and potential for standardization improve procedural outcomes and patient safety, making 3D TOE integration into routine practice highly beneficial and recommended. Full article
(This article belongs to the Special Issue Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future Directions)
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Review

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17 pages, 1468 KiB  
Review
Optimizing Imaging Techniques for Left Atrial Appendage Closure: Insights and Emerging Directions
by Valentina Barletta, Mattia Alberti, Riccardo Agostini, Fausto Pizzino, Giancarlo Trimarchi, Maria Grazia D’Alfonso, Marco Solari, Giulio Zucchelli and Alberto Cresti
J. Clin. Med. 2025, 14(10), 3607; https://doi.org/10.3390/jcm14103607 - 21 May 2025
Viewed by 750
Abstract
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in adults and is associated with significant morbidity and mortality, including an increased risk of stroke, heart failure, dementia, and recurrent hospitalizations. As life expectancy rises, both the incidence and prevalence of AF [...] Read more.
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in adults and is associated with significant morbidity and mortality, including an increased risk of stroke, heart failure, dementia, and recurrent hospitalizations. As life expectancy rises, both the incidence and prevalence of AF continue to grow. Stroke prevention remains a cornerstone of AF management, with oral anticoagulation being the primary strategy to reduce thromboembolic risk. However, despite their advantages, direct oral anticoagulants do not completely eliminate the risk of bleeding complications. For patients in whom anticoagulation is contraindicated, poorly tolerated, or ineffective at preventing AF-related stroke, interventional alternatives have gained traction. The left atrial appendage (LAA), a primary site of thrombus formation in AF, can be occluded through a catheter-based procedure known as left atrial appendage closure (LAAC) or left atrial appendage occlusion (LAAO). This review aims to provide imaging specialists with a comprehensive understanding of their role in LAAC, underscoring the importance of a multidisciplinary approach to enhance patient selection, procedural success, and long-term efficacy. Full article
(This article belongs to the Special Issue Echocardiographic Imaging in Transcatheter Structural Intervention: Current Practices and Future Directions)
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