Risk Prediction for Gynecological Cancer
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 2471
Special Issue Editor
Interests: gynecological cancers; primary peritoneal cancer; tubo-ovarian cancer; uterine and cervical cancer; vaginal and vulvar cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Risk prediction for gynaecological cancer is crucial for the early prevention, timely diagnosis, and effective treatment of cervical, endometrial and tubo-ovarian cancers. These cancers pose significant health threats to women worldwide, and understanding risk factors and tools to achieve early diagnosis can help researchers to reduce their incidence and mortality rates. Cervical cancer risk prediction relies heavily on screening and vaccination. Human papillomavirus (HPV) is the primary cause, so regular pap smears and HPV testing are essential, and screening programs and new assessments should be incorporated in clinical practice worldwide. Endometrial cancer, primarily affecting postmenopausal women, is often linked to obesity, diabetes, hypertension, and hormonal imbalances. Predictive models focus on these factors, as well as genetic predispositions and lifestyle choices. Early detection through symptom awareness and ultrasound assessment, both combined with timely endometrial biopsies, is crucial, and in this context, a hysteroscopic approach is of utmost importance. Ovarian cancer presents the greatest challenge due to its often-late diagnosis and subtle early symptoms. Risk factors include age, a family history of ovarian or breast cancer, and genetic mutations like BRCA1 and BRCA2. Risk prediction involves genetic testing, particularly for those with a family history, and regular pelvic exams. Prophylactic surgeries (such as salpingo-oophorectomy) are considered for high-risk individuals. Research into biomarkers and advanced imaging techniques continues to evolve, aiming to improve early detection rates. Integrating these risk prediction strategies into routine healthcare can significantly enhance the prevention and early diagnosis of gynaecological cancers. This Special Issue will highlight recent advances in the context of diagnosis, treatment, and the prediction of prognosis for these malignancies.
Dr. Federico Ferrari
Guest Editor
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Keywords
- cervical cancer
- endometrial cancer
- tubo-ovarian cancer
- diagnosis
- treatment
- prognosis
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