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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence in Exercise, Rehabilitation and Health Promotion: A Clinical Perspective

edited by

Ki-Hyuk Lee

and

Koji Koyama

submission deadline 20 May 2026 | Viewed by 132 | Submission Open

Keywords: artificial intelligence; machine learning and deep learning; large language models (LLMs); explainable AI; exercise and physical activity; rehabilitation and sports medicine; clinical applications; chronic disease and preventive health; digital health and big data analytics

(This special issue belongs to the Section Sports Medicine)

Surgery in the Era of Neoadjuvant Immune Checkpoint Inhibitors Therapy for Thoracic Oncology

edited by

Mohsen Ibrahim

submission deadline 20 May 2026 | Viewed by 127 | Submission Open

Keywords: neoadjuvant therapy; immune checkpoint inhibitors; unresectable disease; lung cancer; locally advanced lung cancer

(This special issue belongs to the Section General Surgery)

Spine Surgery: Current Challenges and Opportunities

edited by Kambiz Sarahrudi

submission deadline 20 May 2026 | Viewed by 117 | Submission Open

Keywords: vertebral fracture; spine trauma; spinal cord injury; adjacent segment degeneration; infection; spondylodiscitis; verte-bral metastasis; osteoporotic fracture; fracture of sacrum; disk degeneration; degenerative spine surgery; minimally invasive spine surgery

(This special issue belongs to the Section Orthopedics)

Current Challenges in Oral and Maxillofacial Surgery

edited by

Federica Canfora

and Lucia Memé

submission deadline 20 May 2026 | Viewed by 111 | Submission Open

Keywords: oral and maxillofacial surgery; surgical management; virtual surgical planning; postoperative management; orthog-nathic surgery; reconstructive techniques; minimally invasive surgery; digital technologies; 3D printing

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Neurovascular Interventions: Evolving Techniques and Insights

edited by Delia Cannizzaro

submission deadline 20 May 2026 | Viewed by 104 | Submission Open

Keywords: endovascular treatment; intracranial aneurysms; AI in neurointerventional surgery; intracranial vascular malformation; new endovascular device

(This special issue belongs to the Section Clinical Neurology)

Clinical Progress in Oral and Maxillofacial Surgery

edited by Luis M. Junquera and Giuseppe Consorti

submission deadline 20 May 2026 | Viewed by 99 | Submission Open

Keywords: oral and maxillofacial surgery; craniofacial surgery; facial deformity; cleft lip and palate; TMJ surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Challenges in Pancreatitis Management

edited by

Yusuke Tando

submission deadline 20 May 2026 | Viewed by 96 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; medical management; surgical management; nutritional support; pancreatic diabetes; clinical research; reviews

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Perioperative Pain Management: 3rd Edition

edited by

Felice Eugenio Agro

Giuseppe Pascarella

and

Fabio Costa

submission deadline 20 May 2026 | Viewed by 96 | Submission Open

Keywords: anesthesia and intensive care; pain management; spinal anesthesia; postoperative pain; breast surgery; fascial plane blocks; abdominal surgery; cardiac surgery; thoracotomy; knee surgery; orthopedic surgery; hip surgery; ultrasound

(This special issue belongs to the Section Anesthesiology)

Anesthesia in Head and Neck Surgery

edited by

Luigi V. La Via

and Antonino Maniaci

submission deadline 20 May 2026 | Viewed by 94 | Submission Open

Keywords: airway management; hemodynamic stability; perioperative monitoring; head and neck surgery; anesthesia

(This special issue belongs to the Section Anesthesiology)

Diagnosis and Treatment of Connective Tissue Diseases: A Clinician's Perspective: 2nd Edition

edited by

Agnieszka Żebrowska

Adam Reich

and Aleksandra Dańczak-Pazdrowska

submission deadline 20 May 2026 | Viewed by 94 | Submission Open

Keywords: connective tissue diseases; lupus erythematosus; scleroderma; dermatomyositis; MCTD; clinical picture; spectrum of clinical symptoms; treatment; complications; clinical follow-up

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Trends and Prospects in Urology Surgery: 2nd Edition

edited by

Lazaros Tzelves

submission deadline 20 May 2026 | Viewed by 89 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; endourology; minimally invasive surgery; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Strategies in Complex Hand Trauma: Bridging Orthopedics, Plastic Surgery and Rehabilitation

edited by Clarisa Simón-Pérez and

Pedro Hernandez-Cortes

submission deadline 20 May 2026 | Viewed by 86 | Submission Open

Keywords: complex hand trauma; orthopedics; plastic surgery; microsurgery; rehabilitation; functional reconstruction; multidis-ciplinary management

(This special issue belongs to the Section General Surgery)

Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies

edited by Carla Contaldi

submission deadline 20 May 2026 | Viewed by 86 | Submission Open

Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification

(This special issue belongs to the Section Cardiology)

Prevention, Treatment, and Prognosis of Cerebral Aneurysms

edited by

Murai Yasuo

submission deadline 20 May 2026 | Viewed by 86 | Submission Open

Keywords: cerebral aneurysm; subarachnoid hemorrhage; clipping; interventional surgery; mortarity; long-term; surgical com-plication; bypass

(This special issue belongs to the Section Clinical Neurology)

Clinical Research Progress in Atrial Fibrillation

edited by

Roddy Hiram

submission deadline 20 May 2026 | Viewed by 86 | Submission Open

Keywords: atrial fibrillation; atrial arrhythmias; cardiac fibrosis; inflammation; electrical remodeling

(This special issue belongs to the Section Cardiology)

Advances in Demyelinating and Neuroinflammatory Disorders

edited by

Julían Benito-Léon

submission deadline 20 May 2026 | Viewed by 85 | Submission Open

Keywords: multiple sclerosis; neuromyelitis optica spectrum disorder; MOG antibody– associated disease; neuroinflammation; biomarkers; advanced imaging; disease-modifying therapies; clinical outcomes

(This special issue belongs to the Section Clinical Neurology)

Alcohol-Associated Liver Disease: Diagnosis and Treatment of Acute and Chronic Conditions

edited by Halina Cichoz-Lach and

Beata Kasztelan-Szczerbińska

submission deadline 20 May 2026 | Viewed by 85 | Submission Open

Keywords: alcohol-associated liver disease; alcohol-associated hepatitis; alcohol-associated liver cirrhosis; excessive alcohol intake; oxidative liver damage; gut– liver axis; organ-to-organ crosstalk

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Presbyopia, Laser, Cataract and Refractive Surgery: State-of-the-Art Research: Second Edition

edited by

Ivo Guber

submission deadline 20 May 2026 | Viewed by 82 | Submission Open

Keywords: presbyopia; cataract surgery; refractive surgery; femtosecond laser; intraocular lenses; corneal refractive procedures; phakic intraocular lenses; visual outcomes; patient-reported outcomes; surgical innovations

(This special issue belongs to the Section Ophthalmology)

Clinical Perspectives on Obesity and Bariatric Surgery: Outcomes and Complications

edited by Dilhana S. Badurdeen

submission deadline 20 May 2026 | Viewed by 81 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; Roux-en-Y Gastric Bypass (RYGB); sleeve gastrectomy; revisional bariatric surgery; complications; outcomes; weight loss maintenance; metabolic syndrome; type 2 diabetes remission; nutritional deficiencies; gastrointestinal adaptation; quality of life; long-term follow-up

(This special issue belongs to the Section General Surgery)

Acute Coronary Syndromes | Circulation Research

edited by

Leslie Marisol Lugo Gavidia

and

Roberto Pedrinelli

submission deadline 20 May 2026 | Viewed by 81 | Submission Open

Keywords: acute coronary syndromes; cardiovascular risk; individualized therapy; STEMI; risk factors

(This special issue belongs to the Section Cardiology)

The Current Trend in the Management of Bruxism and Temporomandibular Disorders, 2nd Edition

edited by

Luís Eduardo Almeida

submission deadline 20 May 2026 | Viewed by 81 | Submission Open

Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Ocular Surgeries: Innovations in Cataract, Retinal, and Beyond

edited by

Seung Pil Bang

and Yu Cheol Kim

submission deadline 20 May 2026 | Viewed by 80 | Submission Open

Keywords: cataract surgery; retinal surgery; intraocular lenses; femtosecond laser; minimally invasive vitrectomy; ocular imaging; surgical innovation; ocular trauma; corneal transplantation; glaucoma surgery

(This special issue belongs to the Section Ophthalmology)

Clinical Aspects of Return to Sport After Injuries: 2nd Edition

edited by

Anna Mika

and

Łukasz Oleksy

submission deadline 20 May 2026 | Viewed by 79 | Submission Open

Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine

(This special issue belongs to the Section Sports Medicine)

Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition

edited by

Elad Asher

submission deadline 20 May 2026 | Viewed by 78 | Submission Open

Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances in Hemodialysis: 2nd Edition

edited by Maurizio Bossola

submission deadline 20 May 2026 | Viewed by 77 | Submission Open

Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy

(This special issue belongs to the Section Nephrology & Urology)

Foot and Ankle Surgery: Clinical Challenges and New Insights: 2nd Edition

edited by

Byung-Ki Cho

submission deadline 20 May 2026 | Viewed by 77 | Submission Open

Keywords: hallux valgus; minimal invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis

(This special issue belongs to the Section Orthopedics)

Advances in Diagnosis and Management of Scoliosis

edited by

Peter G. Passias

submission deadline 20 May 2026 | Viewed by 70 | Submission Open

Keywords: scoliosis; spinal deformities; therapeutic strategies; personalized care; quality of life

(This special issue belongs to the Section Orthopedics)

Neurological Surgery: Clinical Advances and AI-Driven Innovations

edited by Ali A. Alattar

submission deadline 20 May 2026 | Viewed by 69 | Submission Open

Keywords: neurosurgery; artificial intelligence; machine learning; deep learning; radiomics; image segmentation; surgical video analytics; navigation and robotics; predictive modeling; clinical decision support

(This special issue belongs to the Section Clinical Neurology)

The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications

edited by

Jonathan Guez

and

Rotem Saar

submission deadline 20 May 2026 | Viewed by 67 | Submission Open

Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications

(This special issue belongs to the Section Mental Health)

Acute Medical Threats: Evidence-Driven Strategies in Emergency Medicine

edited by

Alexandra Arvanitaki

submission deadline 20 May 2026 | Viewed by 63 | Submission Open

Keywords: emergency medicine protocols; acute medical care; trauma management; resuscitation; critical care; infectious disease preparedness

(This special issue belongs to the Section Emergency Medicine)

Spine Surgery and Rehabilitation: Technical Nuances and Outcomes

edited by Sehan Park and Dong-Ho Lee

submission deadline 20 May 2026 | Viewed by 63 | Submission Open

Keywords: spine surgery; rehabilitation; postoperative outcomes; surgical techniques; patient centered perspective

(This special issue belongs to the Section Orthopedics)

Contemporary Advances in Joint Arthroplasty: Optimizing Outcomes and Expanding Indications

edited by

Ashim Gupta

and

Hugo C. Rodriguez

submission deadline 20 May 2026 | Viewed by 62 | Submission Open

Keywords: joint arthroplasty; total joint replacement; revision arthroplasty; robotic-assisted surgery; periprosthetic joint infection (PJI); enhanced recovery after surgery (ERAS); machine learning; artifical intelligence

(This special issue belongs to the Section Orthopedics)

Myocardial Infarction: Current Status and Future Challenges—2nd Edition

edited by Isaac Pascual and

Rebeca Lorca

submission deadline 20 May 2026 | Viewed by 61 | Submission Open

Keywords: myocardial infarction; acute coronary syndrome (ACS); ischemic heart disease; coronary artery disease (CAD); percutaneous coronary intervention; pharmacological therapy; cardiovascular risk factors

(This special issue belongs to the Section Cardiology)

The Application of Mechanical Circulatory Support Within Cardiology Practice

edited by

Takami Yoshiyuki

submission deadline 20 May 2026 | Viewed by 60 | Submission Open

Keywords: mechanical circulatory support (MCS); cardiogenic shock; intra-aortic balloon pumping (IABP); extracorporeal membranous oxygenation (ECMO); Impella; ventricular assist device (VAD)

(This special issue belongs to the Section Cardiology)

Bladder Cancer: Diagnosis, Treatment and Future Opportunities

edited by

Jørgen Bjerggaard Jensen

submission deadline 20 May 2026 | Viewed by 60 | Submission Open

Keywords: urology; bladder cancer; urothelial cancer; non-muscle invasive bladder cancer; muscle invasive bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

Transcatheter Aortic Valve Implantation and Replacement: Prospects and Challenges—2nd Edition

edited by Konstantinos Toutouzas and

Panayotis Vlachakis

submission deadline 20 May 2026 | Viewed by 58 | Submission Open

Keywords: TAVI; aortic stenosis; valve-in-valve; structural heart disease; TAVI-in-TAVI

(This special issue belongs to the Section Cardiology)

Valvular Heart Disease: Current Knowledge and Therapeutic Prospects

edited by Simona Mega

submission deadline 20 May 2026 | Viewed by 52 | Submission Open

Keywords: valvular heart disease; echocardiographic assessment; cardiovascular imaging; valvular regurgitation; valvular stenosis; structural heart intervention; minimally invasive cardiac surgery; catheter-based interventions

(This special issue belongs to the Section Cardiology)

Audiology and Phoniatrics in Head and Neck Surgery: Functional Assessment, Rehabilitation Strategies, and Quality of Life Outcomes

edited by

Claudia Cassandro

submission deadline 20 May 2026 | Viewed by 42 | Submission Open

Keywords: audiology; phoniatrics; voice disorders; hearing preservation; speech rehabilitation; head and neck surgery; functional outcomes; quality of life; voice analysis; audiometry; cochlear implants; dysphagia; laryngeal surgery

(This special issue belongs to the Section Otolaryngology)

Osteoporosis: A Renascent Impact of Vertebral Fractures in the Diagnosis and Management

edited by Csaba Horvath

submission deadline 20 May 2026 | Viewed by 42 | Submission Open

Keywords: osteoporosis; vertebral fractures; imminent fracture risk; FRAX; bone densitometry; vertebral fracture assessment

(This special issue belongs to the Section Orthopedics)

Clinical Challenges in Uterus Transplant Management

edited by Giuliano Testa

submission deadline 20 May 2026 | Viewed by 40 | Submission Open

Keywords: uterus transplant; absolute uterine infertility; fertility treatment; immunosuppression in uterus transplant; pregnancy complications; uterine donor evaluation

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease

edited by Josuel Ora

submission deadline 20 May 2026 | Viewed by 39 | Submission Open

Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Venous Thrombosis

edited by Nicola Mumoli

submission deadline 20 May 2026 | Viewed by 35 | Submission Open

Keywords: direct oral anticoagulants (DOACs); cancer-associated thrombosis (CAT); venous thromboembolism (VTE); thrombolytic therapy; post-thrombotic syndrome (PTS); artificial intelligence in VTE prediction

(This special issue belongs to the Section Vascular Medicine)

Clinical Features and Management of Psychosis

edited by

Maria Margariti

George Konstantakopoulos

and Michael Hadjulis

submission deadline 22 May 2026 | 4 articles | Viewed by 11022 | Submission Open

Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis

(This special issue belongs to the Section Mental Health)

Thoracic Surgery: Recent Developments and Future Challenges

edited by

Marco Andolfi

and Lucio Cagini

submission deadline 22 May 2026 | 1 articles | Viewed by 2789 | Submission Open

Keywords: VATS; RATS; ERAS; sublobar resection; minimally invasive thoracic surgery; target therapy; nodule localization

(This special issue belongs to the Section Respiratory Medicine)

Thrombotic Risk and Its Management Across Diverse Clinical Settings

edited by Samuel Bogdan Todor and Ana Maria Vlǎdǎreanu

submission deadline 22 May 2026 | 1 articles | Viewed by 1642 | Submission Open

Keywords: thrombosis; thrombotic risk; hematologic disorders; thrombophilia; myeloproliferative neoplasms; antithrombotic therapy; cardiovascular diseases; biomarkers

(This special issue belongs to the Section Hematology)

Clinical Updates on Rheumatoid Arthritis: 2nd Edition

edited by Francesca Bandinelli

submission deadline 22 May 2026 | 1 articles | Viewed by 1635 | Submission Open

Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease

(This special issue belongs to the Section Immunology & Rheumatology)

Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management

edited by

Andreas Mitsis

and

Nikolaos Kadoglou

submission deadline 22 May 2026 | Viewed by 294 | Submission Open

Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management

(This special issue belongs to the Section Cardiology)

Role of Platelet in Inflammation, Infection, and Immune Response

edited by

Amir Houshang Shemirani

submission deadline 22 May 2026 | Viewed by 213 | Submission Open

Keywords: platelets; platelet count; dual antiplatelet therapy; inflammation; thrombosis; inflammation; hemostasis; immune response

(This special issue belongs to the Section Hematology)

Clinical Pharmacology: Adverse Drug Reactions

edited by

Andrej Belančić

and Ivana Mudnić

submission deadline 25 May 2026 | 6 articles | Viewed by 26495 | Submission Open

Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety

(This special issue belongs to the Section Pharmacology)

Neurovascular Diseases: Clinical Advances and Challenges

edited by

Roberto Colasanti

, Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez

submission deadline 25 May 2026 | 12 articles | Viewed by 24516 | Submission Open

Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms

(This special issue belongs to the Section Clinical Neurology)

Displaying special issue 1151-1200 on page 24 of 32.

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