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Advances in Lupus Erythematosus and Lupus Nephritis: Pathogenesis, Biomarkers and Treatments, 2nd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 2

Special Issue Editor


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Guest Editor
Department of Medicine, Tuen Mun Hospital, Tsing Chung Koon Road, New Territories, Hong Kong
Interests: lupus; biologics; biomarkers; therapeutics; osteoporosis; rheumatoid arthritis; lupus nephritis; targeted therapies
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Special Issue Information

Dear Colleagues,

Despite the availability of new immunomodulatory therapies, the survival of systemic lupus erythematosus (SLE) has failed to improve since the mid-1990s. Today, the need to develop novel SLE management strategies that incorporate a better balance of efficacy and toxicity has yet to be met. 

These strategies include earlier recognition of major organ manifestations, such as lupus nephritis (LN), early aggressive therapies for high-risk patients to minimize organ damage, better monitoring of disease activity, maintenance therapies to reduce disease flares, and enhancement of medication adherence. The ultimate goal of SLE therapy is to induce and maintain a long-lasting remission, minimize organ damage and treatment-related complications, and to improve quality of life. 

Volume 1.0 of the Special Issue “Advances in Lupus Erythematosus and Lupus Nephritis: Pathogenesis, Biomarkers and Treatments” (https://www.mdpi.com/journal/ijms/special_issues/1UXZ95ODM6) has been highly successful. We therefore aim to reopen this topic as volume 2.0. This second Special Issue covers works in different research areas of SLE. We welcome original articles, clinical trials, laboratory works, reviews, and meta-analyses. 

Topics of interest include, but are not limited to, the following:

  1. Genomic, transcriptomic, and metabolomic studies of systemic lupus erythematosus/ lupus nephritis (SLE/LN);
  2. Classification criteria;
  3. Disease activity indices;
  4. Organ damage and comorbidities;
  5. Serological, urine, and tissue biomarkers for the prediction of SLE/LN prognosis and flares;
  6. Novel therapeutic modalities and strategies for SLE and LN.

Dr. Chi Chiu Mok
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lupus erythematosus
  • lupus nephritis
  • SLE
  • LN
  • organ damage
  • pathogenesis
  • biomarkers
  • genomic
  • transcriptomic
  • metabolomic
  • treatments
  • therapeutic

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Published Papers

This special issue is now open for submission.
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