Advances in Aging and Alzheimer’s Disease Research: From Molecular Mechanisms to Therapeutics—2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 34
Special Issue Editor
Interests: ageing; Alzheimer’s disease; bioinformatics; RNA-seq; Parkinson’s disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Aging is an inevitable process common to all humans and a major risk factor for several age-related diseases, including neurodegenerative diseases. During human aging, neurodegenerative diseases and their associated cognitive deficits, which affect human health and life, are prevalent. Alzheimer's disease (AD) is one of the most common neurodegenerative brain diseases, a main symptom of which is the functional decline and disruption of the blood–brain barrier, which is characterized by the accumulation of amyloid-β plaques, neural disassembly, synaptic dysfunction, and cellular damage to neurons, as well as other brain cells in the brain parenchyma. These effects can lead to memory impairment, behavioral changes, the loss of cognitive function, and dementia.
For this Special Issue of the International Journal of Molecular Sciences, we aim to gather insights into the pathogenesis of Alzheimer's disease, barrier dysfunction, neuronal transmission, brain changes associated with aging, oxidative stress, mitochondrial dysfunction, and the identification of amyloid, tau, and p-tau, as well as other biomarkers.
Dr. Lilach Soreq
Guest Editor
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Keywords
- aging
- Alzheimer’s disease
- bioinformatics
- RNA-seq
- Parkinson’s disease
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