Non-Coding RNAs as Key Regulators in Human Disease Processes
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025
Special Issue Editor
Special Issue Information
Dear Colleagues,
Non-coding RNAs (ncRNAs) have emerged as key regulators of gene expression and cellular function, profoundly influencing a wide range of physiological and pathological processes. In recent years, increasing evidence has highlighted the pivotal role of ncRNAs—including microRNAs, long non-coding RNAs, and circular RNAs—in the onset and progression of human diseases, ranging from cancer and neurodegenerative disorders to metabolic and cardiovascular diseases. These molecules not only serve as crucial players in disease mechanisms but also represent promising diagnostic biomarkers and therapeutic targets. This Special Issue aims to gather original research articles and comprehensive reviews that explore the functional roles of ncRNAs in human pathologies, their underlying molecular mechanisms, and their translational potential in clinical settings.
Dr. Beatrice Polini
Guest Editor
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Keywords
- non-coding RNAs
- microRNAs
- long non-coding RNAs
- circular RNAs
- biomarkers
- therapeutic targets
- molecular mechanisms
- RNA-based therapy
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