Biological Pathways and Nutraceutical Compounds in Genetic Disease Treatment

Dear Colleagues,

Nutraceutical compounds are plant- or animal-derived substances that are used for health benefits. These compounds are usually taken at a level higher than one would obtain from the source food itself. Much focus has been on the use of nutraceuticals to improve general health, prevent chronic disease, increase lifespan, or delay aging in general. In this Special Issue, we seek research articles and reviews that provide new findings, up-to-date statuses, and future perspectives on nutraceutical uses to treat genetic diseases. Research involving trials of nutraceuticals for one of the ~1200 rare genetic diseases, such as abetalipoproteinemia, Prader–Willi syndrome, ornithine transcarbamylase deficiency, or pseudoachondroplasia, among others, is especially welcome. Studies on more common genetic conditions, such as obesity, bowel and digestive disorders, Alzheimer’s disease, cystic fibrosis, deafness, or Tay Sachs disease, among others, are also appropriate for this Special Issue. Moreover, preclinical animal model studies and studies using stem cells or cell line models examining the molecular and biological pathways affected by the nutraceutical compounds are welcome in this Special Issue. Submitted articles should include results at the molecular level, including changes in RNA and protein expression, DNA methylation, cell signaling molecules, microbiome changes, and similar findings, as appropriate for the International Journal of Molecular Sciences.

Dr. Deborah J. Good
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.