Evolving Landscape of Cardiovascular Pathophysiology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 25 July 2026 | Viewed by 74
Special Issue Editor
Interests: complement immunity; complement anaphylatoxin receptor signaling; complement role in autoimmune and infectious diseases; complement dysfunction in rheumatoid arthritis-related cardiopulmonary fibrosis
Special Issue Information
Dear Colleagues,
Cardiovascular diseases (CVDs) continue to represent the leading cause of morbidity and mortality globally, causing a significant healthcare burden, despite the fact that prevention and treatment methods have advanced considerably. Understanding the underlying pathophysiological mechanisms is essential in developing innovative therapies and improving patient outcomes. Drawing on current trends and recent breakthroughs in the field of cardiovascular medicine, this Special Issue, “Evolving Landscape of Cardiovascular Pathophysiology”, will bring together cutting-edge research articles and comprehensive reviews that illuminate the complex biological processes driving cardiovascular disorders. We will focus on transformative developments that are reshaping our understanding and treatment of heart disease. Contributions should highlight the convergence of cutting-edge technologies and traditional research to bridge the gap between bench science and clinical applications. This Special Issue will feature research exploring emerging cardio-metabolic insights, including endothelial metabolomics, inflammatory mechanisms, and single-cell transcriptomics in cardiac adversities in humans and experimental models. Insights into the gut–heart axis, including the role of gut dysbiosis in promoting atherosclerosis, hypertension, and heart failure, can aid in identifying potential therapeutic targets for balancing the gut microbiota. We also welcome research on AI-based technologies for predicting conditions such as cardiomyopathies and heart failure. We also encourage work on precision diagnostics and therapeutic innovations for this Special Issue.
Dr. Pooja Shivshankar
Guest Editor
Manuscript Submission Information
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Keywords
- biomarker discovery in cardiovascular pathophysiology
- precision diagnostics-novel contrast agents combined with PET/CT, MRI
- machine learning/AI and clinical implementations in cardiology
- cardio-metabolic disease, inflammation and immunity in cardiovascular diseases, mechanisms of non-coding RNAs and microRNAs in cardiac diseases
- translational research in large animals bridging the rodent re-search with human pathophysiology
- targeted therapies- genetic therapies/gene editing approach (CRISPR), stem cell therapies, and therapeutic mRNA and siRNA-based approaches
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