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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Osteoimmunology: Interactions of the Bone and Immune System

edited by

Galliera Emanuela Rita

submission deadline 20 Feb 2026 | 1 articles | Viewed by 4762 | Submission Open

Keywords: osteoimmunology markers; bone infection; inflammation and bone; immune response and bone; diagnostic and prognostic markers; bone remodeling; osteoclasts; immune-mediated bone diseases; bone– immune interface

(This special issue belongs to the Section Molecular Immunology)

Inflammation in Pregnancy and Childbirth

edited by

Małgorzata Szczuko

and Maciej Ziętek

submission deadline 20 Feb 2026 | 2 articles | Viewed by 4754 | Submission Open

Keywords: pregnancy; labor; eicosanoid; chronic inflammation; cytokines; intestinal dysbiosis; mitogen-activated protein kinase; nuclear factor kappa-light-enhancer-activated B cell; maresins; resolvins and protectins

(This special issue belongs to the Section Molecular Immunology)

The Extracellular Matrix in Physiopathology

edited by

Eric Huet

submission deadline 20 Feb 2026 | 4 articles | Viewed by 4673 | Submission Open

Keywords: extracellular matrix; glycosaminoglycans; matrix metalloproteinases; tissue remodeling; cell interactions; physiopathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Brain-Body Interactions in Mental Disorders: Molecular Mechanisms and Therapeutics

edited by Yan-Xue Xue

submission deadline 20 Feb 2026 | 1 articles | Viewed by 4652 | Submission Open

Keywords: mental disorders; brain– body interactions; neural mechanisms; therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Cervical Cancer and Its Therapy

edited by Ilaria Cuccu and

Violante Di Donato

submission deadline 20 Feb 2026 | 1 articles | Viewed by 4454 | Submission Open

Keywords: cervical cancer; cervical cancer surgery; fertility-sparing techniques; targeted therapy; immunotherapy; immune checkpoint inhibitors; DNA damage repair inhibitors; antibody– drug conjugates; precision medicine; oncological outcomes

(This special issue belongs to the Section Molecular Oncology)

Drug Therapy of Systemic Lupus Erythematosus

edited by Dionysis Nikolopoulos

submission deadline 20 Feb 2026 | 3 articles | Viewed by 4413 | Submission Open

Keywords: systemic lupus erythematosus; treatment; drugs; tailored strategies; precision medicine; biologics; cell therapy; randomized clinical trials

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Structural and Functional Properties of G-Quadruplexes and Aptamers

edited by

Antonella Virgilio

Veronica Esposito

and

Aldo Galeone

submission deadline 20 Feb 2026 | 5 articles | Viewed by 4407 | Submission Open

Keywords: G-quadruplex structure; aptamer; DNAzyme; catalytic G-quadruplexes

(This special issue belongs to the Section Molecular Biology)

Immune Mechanisms and Biomarkers in Systemic Lupus Erythematosus—Second Edition

edited by

Ioannis Parodis

submission deadline 20 Feb 2026 | 3 articles | Viewed by 4398 | Submission Open

Keywords: systemic lupus erythematosus; lupus nephritis; neuropsychiatric lupus; autoimmunity; biomarkers; B lymphocyte; interferons

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Osteoarthritis Pathways and Biomarker Research

edited by

Előd Ernő Nagy

submission deadline 20 Feb 2026 | 5 articles | Viewed by 4353 | Submission Open

Keywords: osteoarthritis; low-grade inflammation; cartilage chondrocyte; synovial membrane; synovial fluid; subchondral bone; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Aspects of Breast Cancer Metastasis

edited by

Hideki Furuya

submission deadline 20 Feb 2026 | 2 articles | Viewed by 4144 | Submission Open

Keywords: precision medicine; omics-based discovery research (genomics; proteomics; transcriptomics; and radiomics); non-invasive test; liquid biopsy; first-in-class medications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antimicrobial Resistology: A New Approach in the Fight Against Antimicrobial Resistance

edited by

Ziad Daoud

submission deadline 20 Feb 2026 | 2 articles | Viewed by 4137 | Submission Open

Keywords: antimicrobial resistance; resistology; ESBL; AmpC; carbapenem resistance; one health

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Diagnosis and Treatment of Colorectal Cancer

edited by Steven T. Brower and Robert Pergolizzi

submission deadline 20 Feb 2026 | 3 articles | Viewed by 4076 | Submission Open

Keywords: colorectal cancer; biomarkers; epigenetics; targeted therapy; chemoresistance; personalized cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Functional Genomics of Insects: Unraveling Genetic Mechanisms and Applications

edited by

Bin Li

submission deadline 20 Feb 2026 | 4 articles | Viewed by 4051 | Submission Open

Keywords: genomics; comparative genomics; gene regulation networks; developmental biology; metamorphosis; vector biology; insecticide resistance mechanisms; insect– plant interactions; environmental adaptation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Melanoma: Molecular Mechanism and New Agents for Prevention and Therapy

edited by

M. Letizia Motti

submission deadline 20 Feb 2026 | 3 articles | Viewed by 4045 | Submission Open

Keywords: melanoma; therapy resistance; melanoma microenvironment (MME); melanoma plasticity; epigenetic mechanism; predictive markers; prognostic markers; extracellular vesicles; molecular therapy; natural molecules

(This special issue belongs to the Section Molecular Oncology)

Progress in the Use of Graphene and Graphene-Like Materials in Various Applications

edited by Piotr Kamedulski

submission deadline 20 Feb 2026 | 2 articles | Viewed by 4042 | Submission Open

Keywords: graphene; porous carbons; carbon-based materials; 3D graphene; graphene exfoliation; nanotubes; nanomaterials; N-rich nano-porous carbon matrixes; N-rich activated carbons; carbon molecular sieves; hybrid materials; medical applications

(This special issue belongs to the Section Materials Science)

Advances in Stem Cell-Based Regenerative Medicine for Renal Disorders

edited by In-Yong Kim

submission deadline 20 Feb 2026 | 1 articles | Viewed by 4014 | Submission Open

Keywords: chronic kidney disease; acute kidney injury; stem cells; regenerative medicine; stem cell therapy; cellular reprogramming; cell transplantation

(This special issue belongs to the Section Molecular Biology)

Aging: From Molecular Mechanisms and Pathophysiology to Novel Therapeutic Approaches (3rd Edition)

edited by

Darío Acuña-Castroviejo

submission deadline 20 Feb 2026 | 5 articles | Viewed by 3962 | Submission Open

Keywords: human aging; molecular clock; aging genes; epigenetics; nutrigenomics; inflammaging; stem cells; telomeres; mitochondria; brain-gut axis; brain-muscle axis; gut microbiota; chronodisruption

(This special issue belongs to the Section Molecular Biology)

Modulating the Niche: Targeting the Tumor Microenvironment for Enhanced Therapy

edited by

Dong Min Lee

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3771 | Submission Open

Keywords: microenvironment dynamics; immune modulation; biomarker discovery; tumor microenvironment; extracellular matrix; cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Micropollutants in Various Enviroments

edited by

Anna Lenart-Boroń

submission deadline 20 Feb 2026 | 3 articles | Viewed by 3763 | Submission Open

Keywords: airborne microorganisms; antibiotics; antibiotic resistance; circular economy of water; environmental bacteria and fungi; wastewater treatment; waterborne microorganisms; water quality

(This special issue belongs to the Section Molecular Toxicology)

CRISPR/Cas Systems and Genome Editing—3rd Edition

edited by

Dmitry Karpov

submission deadline 20 Feb 2026 | 3 articles | Viewed by 3759 | Submission Open

Keywords: CRISPR/Cas; bacterial argonauts; transcription regulation; genome editing; genome editing tools

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Forensics and the Genetic Foundations of Forensic Biology

edited by

Laura Caine

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3758 | Submission Open

Keywords: molecular forensics; forensic genetics; epigenetics; biological fluid identification; forensic microbiology; sexual assault

(This special issue belongs to the Section Molecular Biology)

New Advances in Neuroscience: Molecular Biological Insights

edited by

Palsamy Periyasamy

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3733 | Submission Open

Keywords: neurodegenerative diseases; neurodevelopmental disorders; neurohiv; drug abuse; neuropharmacology; epigenetics; exosomes; inflammasomes; biomarkers; gene therapy; stem cell therapy; deep brain stimulation; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; autism spectrum disorder; ADHD; dyslexia; neuroinflammation

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms Study of Functional Foods and Nutrients in Human Health Interventions

edited by

Rui Jiao

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3631 | Submission Open

Keywords: functional foods; molecular mechanisms; nutrient bioavailability; chronic disease prevention; health interventions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Erythrocyte Cell Death: Molecular Insights

edited by

Anton Tkachenko

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3626 | Submission Open

Keywords: cell death signaling; eryptosis; erythrocyte senescence; erythrocytes; necroptosis; regulated cell death

(This special issue belongs to the Section Molecular Biology)

Current Developments in Glioblastoma Research and Therapy: 2nd Edition

edited by

Aleksandra Majchrzak-Celińska

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3573 | Submission Open

Keywords: diagnostic; prognostic and predictive biomarkers of glioblastoma; ways to target glioma stem cells; targeting glioblastoma-related signaling pathways; epigenetics of glioblastoma; treatment resistance mechanisms; novel treatment options for glioblastoma; combinatorial therapies; immunotherapy; nanotherapy; the application of CRISPR/Cas9 in glioma research; molecular testing of long-term glioblastoma survivors

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms and Targeted Regulation of Autoimmune Diseases

edited by

Davide Raineri

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3549 | Submission Open

Keywords: autoimmunity; autoimmune diseases; multiple sclerosis; rheumatoid arthritis; lupus; type 1 diabetes; inflammatory bowel disease; biomarkers; immune cells; signaling molecules

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Crop Stress Biology and Molecular Breeding: 5th Edition

edited by

Youxiong Que

submission deadline 20 Feb 2026 | 3 articles | Viewed by 3546 | Submission Open

Keywords: biotic and abiotic stress; variety improvement; crop stress biology; molecular breeding; biological basis; signal transduction pathway; agronomic traits; excellent germplasm

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Associations Between Adipose Tissue and Diseases

edited by

Roberto Cannataro

Erika Cione

and

Maria Cristina Caroleo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3470 | Submission Open

Keywords: lipedema; adipose tissue; adipocyte; adipose organ; body fat; miRNA; ketogenic diet

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Molecular Network, Key Biomarkers, and Therapeutic Targets in Colorectal Cancer

edited by

Katharina M. Robertson

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3415 | Submission Open

Keywords: inflammation; metabolism; tumor-associated macrophages; tumor microenvironment; early-onset colorectal cancer; colorectal neoplasms; obesity; immunotherapy; epigenetics; cytokines; microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Redox Systems in Humans, Animals, Plants and Aquatic Ecosystems and Their Microbiomes

edited by

Eugenio Luigi Iorio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3273 | Submission Open

Keywords: redox systems; aging and disease; nutraceuticals; probiotics; animals; plants; aquatic ecosystems; microbiomes

(This special issue belongs to the Section Molecular Biology)

Molecular Studies of Bone Biology and Bone Tissue: 2nd Edition

edited by

Giovanna Iezzi

submission deadline 20 Feb 2026 | 4 articles | Viewed by 3226 | Submission Open

Keywords: bone; stem cells; immunomodulation; biomaterials; bone regeneration; bone repair; bone diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Micro(nano) Plastics as Endocrine Disruptors in Human Diseases

edited by

Anna Maria Giuseppina Poma

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3208 | Submission Open

Keywords: micro(nano) plastics; estrogens; endocrine disruptors; female reproductive system; breast; colon

(This special issue belongs to the Section Molecular Biology)

Drug-Induced Neurotoxicity and Neurodegeneration: Mechanisms, Models and Implications

edited by

Daniel José Barbosa

and

Renata Silva

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3172 | Submission Open

Keywords: drugs of abuse; pharmaceutical drugs; environmental toxins; drug exposure; neurotoxicity; neurodegeneration; brain health; substance use disorders; therapeutic interventions; in vivo models; in vitro models; in silico models; biomarkers of damage; translational studies

(This special issue belongs to the Section Molecular Neurobiology)

Editorial Board Member's Collection Series: The Memory of the Immune Cells

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3138 | Submission Open

Keywords: immunological memory; innate immune memory; dendritic cells; natural killer cells; macrophage memory

(This special issue belongs to the Section Molecular Immunology)

Intestinal 3D Culture, Organoids and Gut-on-Chip in Intestinal Disorders

edited by

Vanessa D’Antongiovanni

and

Carolina Pellegrini

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3125 | Submission Open

Keywords: 3D cultures; gut-on-chip; intestinal organoids; spheroids; organotypic cultures; morphological studies; pharmacological studies; intestinal cancer; inflammatory bowel disease; intestinal functional disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Adsorbing Materials

edited by Mounia Achak

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3027 | Submission Open

Keywords: adsorption process; adsorbing materials; bio-based adsorbents; regeneration and reusability; pollutant removal; wastewater treatment; industrial and environmental applications

(This special issue belongs to the Section Materials Science)

Acute Kidney Injury: Molecular Mechanism and Targeted Therapeutic Approaches

edited by

Bin Yang

submission deadline 20 Feb 2026 | 3 articles | Viewed by 3001 | Submission Open

Keywords: kidney injury; repair; immunoresponse; biomarker; targeted therapy; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research and Applications of Nanomaterials

edited by

Sónia Carabineiro

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2958 | Submission Open

Keywords: molecular research; application; functionality of nanomaterials; catalysis; environmental science

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Research on Immune Response to Virus Infection and Vaccines

edited by

Giulia Matusali

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2883 | Submission Open

Keywords: immunogenicity; emerging pathogen vaccination; molecular and cellular determinants of vaccine responses in immunocompromised individuals; predictive markers of immune response; laboratory methods to dissect immune responses to infections and vaccinations

(This special issue belongs to the Section Molecular Immunology)

Molecular Biology of Periodontal Disease and Periodontal Pathogens

edited by Yago Leira and

João Botelho

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2880 | Submission Open

Keywords: periodontitis; general medicine; inflammation; bacteraemia; education

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Towards Complex Molecular Cancer Therapies

edited by

Luba Hunáková

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2872 | Submission Open

Keywords: precision medicine; immune system harnessing; targeted therapies TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Oncology)

Advanced Molecular Research in Brain Tumors

edited by

Shiv K. Gupta

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2871 | Submission Open

Keywords: targeted therapy; blood– brain barrier; GBM; glioma; immune checkpoint blockers; TME

(This special issue belongs to the Section Molecular Oncology)

Nucleic Acid Recognition and Pharmaceutical Ligand Design

edited by

Marijana Radić Stojković

and

Atanas Kurutos

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2842 | Submission Open

Keywords: nucleic acid recognition; ligand design; analytical techniques; computational chemistry; therapeutics

(This special issue belongs to the Section Macromolecules)

Microbiome-Immunity Crosstalk and Its Role in Health and Disease

edited by

Ana Isabel Beltrán-Velasco

and Sara Uceda

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2815 | Submission Open

Keywords: gut microbiota; immune system; nutrition; inflammatory processes; dysbiosis; neurodegenerative diseases

(This special issue belongs to the Section Molecular Microbiology)

Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition

edited by

Jyotshna Kanungo

submission deadline 20 Feb 2026 | 3 articles | Viewed by 2807 | Submission Open

Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders

(This special issue belongs to the Section Molecular Biology)

Drugs—from Chemical Structure to Biological Activity

edited by

Sravani Sana

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2784 | Submission Open

Keywords: hit molecule; lead optimization; drug design; virtual screening; molecule descriptors; structure– activity relationship; pharmacokinetic/ADME profile; in vitro biological activity

(This special issue belongs to the Section Molecular Pharmacology)

Pathophysiological Insights, Biomarkers and New Therapeutic Strategies in Immune-Mediated Disorders and Neurodegenerative Diseases

edited by

Eleonora Virgilio

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2748 | Submission Open

Keywords: neurodegeneration; neuroimmunology; inflammation; biomarkers; treatment; pathophysiology; multiple sclerosis; myasthenia gravis; neurodegenerative disease

(This special issue belongs to the Section Molecular Immunology)

Viral Vector-Mediated Genome Editing Therapy

edited by

Izumu Saito

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2683 | Submission Open

Keywords: genome editing; adenovirus vector; knock-in; inherited disease; viral vectors

(This special issue belongs to the Section Molecular Genetics and Genomics)

Stem Cells Research: Advancing Science and Medicine

edited by Susana Rosa

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2673 | Submission Open

Keywords: stem cell; stem cell biology; stem cell-based therapies; regenerative medicine; disease modeling

(This special issue belongs to the Section Biochemistry)

Environmental Heavy Metals with Their Benefits and Risks for Human Health

edited by

Rolf Teschke

submission deadline 20 Feb 2026 | 1 articles | Viewed by 2648 | Submission Open

Keywords: heavy metals; metal compound; iron; copper; cadmium; arsenic; oxidative stress; cell death; toxicology; Wilson disease; hemochromatosis

(This special issue belongs to the Section Molecular Toxicology)

Displaying special issue 851-900 on page 18 of 67.

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