Drug Therapy of Systemic Lupus Erythematosus
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 1019
Special Issue Editor
Special Issue Information
Dear Colleagues,
The landscape of SLE therapy has experienced significant progress following decades of setbacks and challenges, with the approvals of belimumab, anifrolumab, and voclosporin. More importantly, phase II trials have yielded promising results for TYK2 inhibitor deucravacitinib for general SLE and B-cell depletion therapy with obinutuzumab for lupus nephritis, potentially heralding successful phase III trials. Innovative cell therapies, particularly CD19 targeted CAR T-cell therapy, have demonstrated remarkable preliminary efficacy in SLE patients, paving the way for phase II/III trials. This evidence indicates a rapidly evolving field, with the potential to significantly alter SLE management and improve patient outcomes.
This Special Issue will comprehensively summarize the progress in SLE drug therapy over the past decade and explore emerging treatments. We seek submissions of original research, reviews, and clinical trial reports that delve into these advancements. To this end, contributions will highlight new pharmacological agents, cellular therapies, and personalized medicine approaches that are shaping the future of SLE treatment.
Dr. Dionysis Nikolopoulos
Guest Editor
Manuscript Submission Information
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Keywords
- systemic lupus erythematosus
- treatment
- drugs
- tailored strategies
- precision medicine
- biologics
- cell therapy
- randomized clinical trials
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