International Journal of Molecular Sciences

Molecular and Cellular Mechanism in Neuroinflammation Research

edited by

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1926 | Submission Open

Keywords: non-coding RNA; nucleic acids; inflammatory cells; inflammatory mediators; neurotransmitters; neuroinflammation; immune cells; neurodegenerative diseases; cerebrovascular diseases; brain tumors

(This special issue belongs to the Section Molecular Neurobiology)

Oxidative and Redox Signalling in Neurological Diseases

edited by

Malamati Kourti

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1690 | Submission Open

Keywords: gasotransmitters; neurological diseases; oxidative stress; redox signalling; reactive oxygen species (ROS); neuroinflammation; mitochondrial dysfunction; cell death/apoptosis; nitrosative stress; endogenous gas signalling; neuromodulation; neurovascular coupling; therapeutic strategies; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Innovative Strategies and Molecular Insights Into Wound Healing

edited by

Cheong Hoon Seo

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1480 | Submission Open

Keywords: wound healing; tissue regeneration; hypertrophic scar; biomaterials; stem cell therapy; gene therapy; exosomes; burn rehabilitation; inflammation; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antibody Engineering and Therapeutic Applications

edited by

Yong-Seok Heo

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1356 | Submission Open

Keywords: monoclonal antibody (mAb) therapies; antibody engineering; antibody-drug conjugate (ADC); chimeric antigen receptor T cell (CAR-T); bispecific antibody; T-cell engager (TCE); cancer immunotherapy; immunocytokine; AI-driven antibody design; antibody structure and mechanism of action

(This special issue belongs to the Section Molecular Pharmacology)

RNA-Based Regulation in Human Health and Disease

edited by

Alfredo Ciccodicola

and

Sudharshan Setra Janardhana Shetty

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1276 | Submission Open

Keywords: non-coding RNAs (ncRNAs); small nucleolar RNAs (snoRNAs); long non-coding RNAs (lncRNAs); microRNAs (miRNAs); piwi-interacting RNAs (piRNAs); circular RNAs (circRNAs); RNA modifications (m6A; pseudouridylation); RNA-protein interactions; post-transcriptional gene regulation; RNA interference (RNAi); antisense oligonucleotides (ASOs); RNA-binding proteins (RBPs); epitranscriptomics; RNA-based therapeutics; cancer-associated ncRNAs; neurodegenerative diseases and RNA regulation; cardiovascular RNA biology; metabolic disorders and RNA; ribosomal RNA modifications; RNA-targeted drug discovery

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research into Chronic Heart Failure

edited by

Velia Cassano

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1194 | Submission Open

Keywords: heart failure; oxidative stress; cardiac remodeling; cardiomyopathy; proteomic; molecular science

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nutraceuticals and Healthy Aging: Molecular Mechanisms and Therapeutic Perspectives

edited by

Francesca Uberti

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1146 | Submission Open

Keywords: molecular mechanisms of the action of nutraceuticals on cellular aging; nutraceuticals and neuroprotection; effects of nutraceuticals on skin aging; nutraceuticals in the prevention or management of age-related metabolic diseases; interaction between nutraceuticals and gut microbiota in aging; nutraceuticals in bone and joint health; role of nutraceuticals in menopausal management; impact of nutraceuticals on BPH and prostate health; multi-target approaches of nutraceuticals in healthy aging; innovative nutraceutical delivery and formulation strategies to increase bioavailability; clinical and preclinical studies of nutraceuticals in the elderly population

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Neuropharmacological Innovations in Treating Neurodegenerative Diseases

edited by

Gabriela Cioca

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1140 | Submission Open

Keywords: neuropharmacology; neurodegenerative disorders; targeted drug delivery; blood– brain barrier permeability; synaptic modulation; neuroprotective agents; disease-modifying therapies; molecular mechanisms of neurodegeneration; innovative drug targets; translational neuroscience

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of Voltage-Gating and Modulation in Ion Channels

edited by Joao Carvalho de Souza

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1124 | Submission Open

Keywords: voltage-gated ion channels; voltage sensing; voltage sensor coupling; new modulators; ion channel modulation; cell excitability

(This special issue belongs to the Section Molecular Biophysics)

Molecular Genetics and Genomics of Aquatic Crustaceans

edited by

Xianhong Meng

, Falin Zhou and Lingbo Ma

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1016 | Submission Open

Keywords: genome sequencing; epigenomics; CRISPR/Cas9 gene editing; transcriptomics; gene expression profiling; genome-wide association studies (GWASs); quantitative trait loci (QTL) mapping; genomic selection; marker-assisted selection (MAS); molecular markers

(This special issue belongs to the Section Molecular Genetics and Genomics)

25th Anniversary of IJMS: Updates and Advances in Molecular Biology

edited by

Irmgard Tegeder

,

Antonio Ieni

and

Costantino Balestra

submission deadline 31 Jan 2026 | 1 articles | Viewed by 996 | Submission Open

Keywords: next-generation sequencing (NGS); CRISPR-Cas9; liquid biopsy; molecular diagnostics; personalized medicine; genome-wide association studies (GWAS)

(This special issue belongs to the Section Molecular Biology)

Ion Channels as Therapeutic Target: Drug Design and Pharmacological Investigation (3rd Edition)

edited by

Gabriella Guerrini

submission deadline 31 Jan 2026 | 1 articles | Viewed by 938 | Submission Open

Keywords: LGIC; voltage-gated ion channel; other ion channels; biological studies; molecular modeling; drug design; synthesis

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Basic and Translational Research in Colorectal Cancer

edited by

Gina Gheorghe

submission deadline 31 Jan 2026 | 1 articles | Viewed by 907 | Submission Open

Keywords: colorectal cancer; diagnostic and prognostic biomarkers; genetic and epigenetic alterations; MMR/MSI; cytokine profiling; inflammatory mediators; gut microbiota; tumor microenvironment; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Toxicity Induced by Engineered Nanomaterials

edited by

Shan Zienolddiny-Narui

submission deadline 31 Jan 2026 | 1 articles | Viewed by 890 | Submission Open

Keywords: toxicity; occupational health; engineered nanomaterials; physical– chemical characteristics; toxicokinetic; toxicodynamic; in vivo; NAMs; NGRA (new-generation risk assessment)

(This special issue belongs to the Section Molecular Toxicology)

Advances in Molecular Target and Anti-Cancer Therapies

edited by Laura Denisa Dragu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 870 | Submission Open

Keywords: cancer; conventional therapy; targeted therapy; immunotherapy; natural compounds; combinatorial therapy; molecular target; molecular mechanism; drug design; drug resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Th2-Mediated Inflammation in Dermatology: Mechanistic and Therapeutic Perspectives

edited by

Luca Mastorino

submission deadline 31 Jan 2026 | 1 articles | Viewed by 865 | Submission Open

Keywords: Th2 inflammation; inflammatory skin disease; immunology of the skin; type 2 inflammatory diseases; immunophenotype

(This special issue belongs to the Section Molecular Immunology)

New Insights into the Mechanisms of Neurodegeneration and Regeneration: From Bench to Bedside

edited by Irina Ivanova Stoyanova

submission deadline 31 Jan 2026 | 1 articles | Viewed by 839 | Submission Open

Keywords: neurodegeneration; neuroregeneration; molecular neurobiology; brain development; developmental brain disorders; synaptogenesis; synaptic plasticity; cognitive neuroscience; neurotrauma

(This special issue belongs to the Section Molecular Neurobiology)

Abiotic Stress in Plants: Physiological and Molecular Responses

edited by Edyta Zdunek-Zastocka

submission deadline 31 Jan 2026 | 1 articles | Viewed by 833 | Submission Open

Keywords: cold; drought; gene expression; heat; heavy metals; oxidative stress; salinity; stress tolerance; stress perception; stress signaling

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advances in Radiation Oncology: Mechanisms, Immunotherapy and Innovation

edited by Jasna But-Hadžić

submission deadline 31 Jan 2026 | 1 articles | Viewed by 813 | Submission Open

Keywords: molecular radiation oncology; DNA damage response; immunoradiotherapy; radiosensitization; tumor– immune interactions; radiogenomics; predictive biomarkers; combination therapies; translational radiobiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cell Proliferation and Differentiation in Cancer

edited by

Sérgio Paulo Bydlowski

submission deadline 31 Jan 2026 | 1 articles | Viewed by 777 | Submission Open

Keywords: cell signaling; cell transduction; transcriptional and post-transcriptional pathways; growth factors; second messengers; cell proliferation; cell differentiation; cell metabolism; cell death; cell invasion

(This special issue belongs to the Section Molecular Oncology)

Epilepsy: Exploring the Molecular Mechanisms and Potential Medications

edited by

Motohiro Okada

submission deadline 31 Jan 2026 | 1 articles | Viewed by 759 | Submission Open

Keywords: idiopathic epilepsy; genetic epilepsy; transmission; development; signaling; synaptic plasticity; pathophysiology; modulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Functional Nanomaterials

edited by

Łukasz Laskowski

submission deadline 31 Jan 2026 | 1 articles | Viewed by 699 | Submission Open

Keywords: functional materials; nanomaterials; molecular structure; molecular materials; functional molecules; nanotechnology; self-assembly methods

(This special issue belongs to the Section Molecular Nanoscience)

Emerging Strategies Targeting Solid Tumors and the Tumor Microenvironment

edited by Emanuela Berrino and

Giuseppina Catanzaro

submission deadline 31 Jan 2026 | 1 articles | Viewed by 679 | Submission Open

Keywords: cancer; tumor microenvironment; medicinal chemistry; drug design; structure– activity relationships; nanotechnologies; antibody– drug conjugates; non-coding RNAs; epigenetic

(This special issue belongs to the Section Molecular Oncology)

Synthesis, Biosynthesis and Implications of Chalcones

edited by

Pal Perjesi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 678 | Submission Open

Keywords: chalcones; biosynthesis; biochemistry

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms of Plant Virus Infection, Resistance and Control

edited by

Carl Spetz

submission deadline 31 Jan 2026 | 1 articles | Viewed by 675 | Submission Open

Keywords: plant virus; host– pathogen interaction; viral replication; virus movement; RNA silencing; molecular virology; CRISPR; resistance

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Pancreatic Diseases

edited by

Wasif Saif

submission deadline 31 Jan 2026 | 1 articles | Viewed by 673 | Submission Open

Keywords: pancreatic cancer; pancreatic neuroendocrine tumors; KRAS; KRAS inhibitors; KRASG12D inhibitor in pancreatic ductal adenocarcinoma; XPO1 inhibitor; PNET

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Application of Nanomedicine in Cancer Targeting and Treatment

edited by

Kee Siang Lim

submission deadline 31 Jan 2026 | Viewed by 565 | Submission Open

Keywords: nanomedicine; nanoimaging/bioimaging; cancer biology; theranostics; translational nanomedicine

(This special issue belongs to the Section Molecular Nanoscience)

Oral Fibrosis and Oral Cancers: From Molecular Targets to Therapeutics

edited by Ila Pant

submission deadline 31 Jan 2026 | Viewed by 519 | Submission Open

Keywords: OSF; oral cancer; myofibroblast activation; collagen homeostasis; cancer stem cells; immunotherapy; monoclonal antibodies; DNA or RNA based targeted therapy; small molecule inhibitors; targeted nano-delivery systems; resistance to targeted therapies; molecular targets; natural compounds

(This special issue belongs to the Section Molecular Oncology)

Molecular Research in Protein–Ligand Interactions

edited by

Qiaomei Sun

submission deadline 31 Jan 2026 | 1 articles | Viewed by 517 | Submission Open

Keywords: interaction; protein– ligand; computer simulation; docking; molecular simulation

(This special issue belongs to the Section Biochemistry)

Advances in Angiogenesis: From Molecular Insights to Therapeutic Strategies

edited by

Emanuela Pessolano

submission deadline 31 Jan 2026 | 1 articles | Viewed by 516 | Submission Open

Keywords: angiogenesis; molecular signaling; endothelial cells; tumor microenvironment; pro-angiogenic factors; anti-angiogenic therapy; vascular remodeling; hypoxia; VEGF pathway; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic and Molecular Research on the Malaria Parasite

edited by Hajime Hisaeda and

Takashi Imai

submission deadline 31 Jan 2026 | 1 articles | Viewed by 511 | Submission Open

Keywords: plasmodium; malaria parasite; molecular biology; genomics; gene expression; host– parasite interaction; drug resistance; vaccine development

(This special issue belongs to the Section Molecular Microbiology)

The Interactions Between Nutrients and Adipose Tissue

edited by

Junseok Son

submission deadline 31 Jan 2026 | Viewed by 504 | Submission Open

Keywords: adipose tissue; nutrients; metabolic health; insulin resistance; inflammation; energy homeostasis; adipokines; obesity; lipolysis; thermogenesis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms of Thromboinflammation

edited by Ana B. Arroyo

submission deadline 31 Jan 2026 | Viewed by 458 | Submission Open

Keywords: thromboinflammation; coagulation; inflammation; immune system; sepsis; stroke; autoimmune diseases; cancer; hematology; biomarkers; translational medicine

(This special issue belongs to the Section Molecular Immunology)

HIV Infection, Pathogenesis and Treatment

edited by

Mudit Tyagi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 450 | Submission Open

Keywords: HIV Infection; HIV; host immune responses; pathogenesis

(This special issue belongs to the Section Molecular Microbiology)

Antitumor Activity of Natural Product

edited by

Fuad Fares

submission deadline 31 Jan 2026 | 1 articles | Viewed by 438 | Submission Open

Keywords: natural products; cancer treatment; cancer prevention; medicinal plants; medicinal mushrooms

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights into Recent Research in Composite Materials

edited by Aboulfazl Barati

submission deadline 31 Jan 2026 | Viewed by 435 | Submission Open

Keywords: composite materials; molecular-level structure– property relationships; polymer nanocomposites; interfacial interactions; sustainable and biodegradable composites; hybrid organic– inorganic systems

(This special issue belongs to the Section Materials Science)

Advances in Melanoma Immunotherapy and Molecular Mechanisms of Drug Resistance, Second Edition

edited by Antonino Guerrisi and

Italia Falcone

submission deadline 31 Jan 2026 | Viewed by 421 | Submission Open

Keywords: melanoma; targeted therapy; immunotherapy; precision medicine; biomarkers; omics technologies; tumor microenvironment

(This special issue belongs to the Section Molecular Immunology)

Plant Responses to Abiotic Stress: Mechanisms and Adaptations

edited by

Shalini Tiwari

and

Lam-Son Phan Tran

submission deadline 31 Jan 2026 | Viewed by 414 | Submission Open

Keywords: salinity stress; heat and cold stress; oxidative stress; signal transduction; stress-responsive genes; antioxidant defence mechanisms; hormonal regulation; molecular adaptation; epigenetic regulation; plant-microbe interaction; crop improvement; stress-resilient plants

(This special issue belongs to the Section Molecular Plant Sciences)

The Application of an Electron Microscope in the Study of Cell Structure

edited by

Ivana Bocina

submission deadline 31 Jan 2026 | 1 articles | Viewed by 411 | Submission Open

Keywords: intracellular structure; organelles; cell surface structure; immuno-labeling

(This special issue belongs to the Section Molecular Biophysics)

Novel Mechanisms of Receptor Activation

edited by

Zong-Jie Cui

submission deadline 31 Jan 2026 | Viewed by 297 | Submission Open

Keywords: G protein-coupled receptors; nuclear (steroid) hormone receptors; catalytic receptors; receptor structural motifs important for activation; receptor pharmacophores; structure– function correlates; cellular functions; integrated physiology; compartmentalized GPCRs; receptor pharmacology; aryl hydrocarbon receptor (AHR); “ orphan” GPCRs

(This special issue belongs to the Section Biochemistry)

Advances in the Molecular Pathogenesis of Gastrointestinal Malignancies with Implications for Diagnosis and Therapy

edited by Laura Necula

submission deadline 31 Jan 2026 | 1 articles | Viewed by 285 | Submission Open

Keywords: gastrointestinal cancers; biomarkers; early diagnosis; circulating molecules; non-invasive tests

(This special issue belongs to the Section Molecular Oncology)

Advanced Strategies for Melanoma Immunotherapy

edited by

Andrzej Mackiewicz

and

Piotr Rutkowski

submission deadline 31 Jan 2026 | Viewed by 256 | Submission Open

Keywords: melanoma immunotherapy; immune Checkpoint Inhibitors; combination therapies; biomarkers; tumor microenvironment

(This special issue belongs to the Section Molecular Immunology)

Fine-Tuning Proteostasis: Insights into Ubiquitination and Deubiquitination Pathways

edited by

Kwang-Hyun Baek

submission deadline 31 Jan 2026 | Viewed by 253 | Submission Open

Keywords: deubiquitination; homeostasis; posttranslational modification; proteasomal degradation; protein quality control; proteolysis; proteostasis; signaling pathway; small molecule; ubiquitin-proteasome system; ubiquitination

(This special issue belongs to the Section Biochemistry)

Novel Heterocyclic Bioactive Compounds: Design, Synthesis and Biological Evaluation

edited by

Lilia Matei

submission deadline 31 Jan 2026 | Viewed by 233 | Submission Open

Keywords: heterocyclic compounds; drug design; medicinal chemistry; bioactive molecules; structure– activity relationships; synthetic methodologies; molecular mechanisms of action; pharmacological evaluation; therapeutic agents

(This special issue belongs to the Section Biochemistry)

Angiogenin: From Molecular Mechanisms to Clinical Implications

edited by

Iogann Tolbatov

submission deadline 31 Jan 2026 | Viewed by 209 | Submission Open

Keywords: angiogenin; angiogenesis; neuroprotection; cancer; neurodegeneration; biomarker; therapeutic target

(This special issue belongs to the Section Biochemistry)

Coordination Chemistry: From Fundamental Principles to Multifunctional Applications

edited by

Kiril B. Gavazov

submission deadline 31 Jan 2026 | Viewed by 207 | Submission Open

Keywords: coordination compounds; metal– ligand interactions; ligand design and synthesis; spectroscopic characterization; coordination geometry; molecular architecture; ion-association complexes; supramolecular chemistry; catalysis and activation mechanisms; functional materials; metal– organic frameworks; magnetism in coordination compounds; redox-active complexes; environmental and green chemistry applications; sensors and molecular devices; bioinorganic chemistry; medicinal coordination chemistry; theoretical and computational coordination chemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Advances in Research of Estrogen Receptors in Health and Diseases

edited by

Maciej Iek Skrzypczak

submission deadline 31 Jan 2026 | Viewed by 199 | Submission Open

Keywords: estrogen receptors; physiology; pathobiology; cancer; benign diseases and disorders

(This special issue belongs to the Section Biochemistry)

Sphingolipids in Infections, Disorders and Diseases

edited by Elita Avota

submission deadline 31 Jan 2026 | Viewed by 196 | Submission Open

Keywords: sphingolipids; sphingolipid biosynthesis; sphingolipidoses; metabolic disorders; infections; lipidomics; sphingolipid targeting drugs

(This special issue belongs to the Section Biochemistry)

Emerging Therapeutic Potential of Organic Compound in Diseases

edited by

Katarzyna Kotwica-Mojzych

submission deadline 31 Jan 2026 | Viewed by 184 | Submission Open

Keywords: organic compounds; chemical analysis; medicinal chemistry; organic chemistry; organic synthesis; characterization techniques; cancers; chronic diseases; civilization diseases; degenerative and neurodegenerative diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights into Nutrition, Genetics, and Biochemistry: From Mechanisms to Therapeutics

edited by

Anna Cieślińska

and

Edyta Sienkiewicz-Szłapka

submission deadline 31 Jan 2026 | Viewed by 181 | Submission Open

Keywords: nutrigenomics and nutrigenetics; molecular nutrition; oxidative stress and redox biology; epigenetics and diet; lipid and glucose metabolism; inflammatory pathways; transcriptomics; metabolomics; proteomics; mitochondrial dysfunction and nutrition; biomarkers of diet-related disease; precision nutrition and molecular therapeutics

(This special issue belongs to the Section Molecular Biology)

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