Angiogenin: From Molecular Mechanisms to Clinical Implications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 5
Special Issue Editor
Interests: computational bioinorganic chemistry; inorganic medicinal chemistry; protein metalation; metalloproteins; metal-based drugs; metal-based anticancer agents; metal-based antimicrobial agents; metal ions in biological milieu
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Angiogenin (ANG), a member of the RNase A superfamily, has emerged as a multifaceted protein with critical roles in various physiological and pathological processes. Initially identified for its potent angiogenic activity, ANG's functions extend far beyond vascularization and include neuroprotection, cell proliferation, stress response, and ribosomal biogenesis. Its involvement in diverse cellular pathways underscores its significance as a potential therapeutic target and biomarker in various diseases.
The intricate molecular mechanisms underlying ANG's pleiotropic effects are still being actively elucidated. Research continues to uncover its interactions with various cellular components, its enzymatic activity, and its modulation by post-translational modifications. Understanding these fundamental mechanisms is crucial for harnessing ANG's therapeutic potential and mitigating its detrimental roles in disease.
This Special Issue will consolidate cutting-edge research on angiogenin, bridging the gap between our understanding of the fundamental molecular mechanisms involved in its action and its clinical significance. We invite original research articles, comprehensive reviews, and focused mini-reviews that explore angiogenin's roles in health and disease, including but not limited to its involvement in cancer, neurodegenerative disorders, infectious diseases, and inflammatory conditions. Studies focusing on novel therapeutic strategies targeting ANG, as well as its utility as a diagnostic or prognostic marker, are particularly encouraged. This Special Issue will provide a comprehensive overview of the current state of angiogenin research, highlighting its vast potential for future translational applications.
Dr. Iogann Tolbatov
Guest Editor
Manuscript Submission Information
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Keywords
- angiogenin
- angiogenesis
- neuroprotection
- cancer
- neurodegeneration
- biomarker
- therapeutic target
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