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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Intercellular Adhesion and Inflammatory Response in Cancer
edited by Anna Pryczynicz
submission deadline 20 Apr 2026 | Viewed by 186 | Submission Open
Keywords: adhesion; cancer; cancer therapy; inflammation; microenvironment
(This special issue belongs to the Section Molecular Biology)
The Impact of Circulating Biomarkers and Metabolites on Cardiometabolic Disease and Cancer: New Insights and Therapeutic Opportunities
edited by Melania Gaggini and
submission deadline 20 Apr 2026 | Viewed by 185 | Submission Open
Keywords: lipidomic; metabolomic; lipotoxicity; oxidative stress; amino acids; metabolic disease; cardiovascular risk; tumorigenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Influence of Genetics on Lymphatic System Diseases submission deadline 20 Apr 2026 | Viewed by 178 | Submission Open
Keywords: lymphatic system; gene expression; disease model; medical application; lymphatic development; lymphatic function
(This special issue belongs to the Section Molecular Genetics and Genomics)
Bioactive Compounds in Bee Products: Chemistry, Mechanisms of Action and Nutritional Applications submission deadline 20 Apr 2026 | Viewed by 178 | Submission Open
Keywords: honey; propolis; royal jelly; polyphenols; nutritional properties; bioactivity; analytical and isolation methods; bee pollen
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanism and Pharmacological Target of Neuroprotection
edited by
submission deadline 20 Apr 2026 | Viewed by 177 | Submission Open
Keywords: neurodegeneration; animal model; brain regeneration; pharmacological drug; molecular analysis
(This special issue belongs to the Section Molecular Neurobiology)
Metabolic Dependencies of the Influence of Intestinal Microbiota During Pregnancy, Childbirth and Infancy
edited by Małgorzata Szczuko and Maciej Ziętek
submission deadline 20 Apr 2026 | Viewed by 176 | Submission Open
Keywords: microbiota; dysbiosis; intestinal microbiome; LPS; zonulin; calprotectin; occludin; SCFA; citrulline; glucagon-like peptide (GLP)-2; LPS binding protein (LBP); amyloid A; intestinal leakage
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
The Role of Transcription Factors in Cancer
edited by
submission deadline 20 Apr 2026 | Viewed by 175 | Submission Open
Keywords: transcription factor; oncogene; tumor suppressor; nuclear receptor; genetic regulation; post-translational regulation; biomarker; drug target
(This special issue belongs to the Section Molecular Oncology)
Molecular-Scale Design, Synthesis, and Applications of (Photo)Electrochemical Materials for Sustainable Energy and Environmental Solutions
edited by and
submission deadline 20 Apr 2026 | Viewed by 174 | Submission Open
Keywords: molecular-scale material engineering; photoelectrocatalysis/electrocatalysis; sustainable energy conversion; atomic-precision synthesis; environmental remediation technologies
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
The Role of Micronutrients in Cancer Prevention
edited by Jacek Baj
submission deadline 20 Apr 2026 | Viewed by 170 | Submission Open
Keywords: micronutrient; metallomics; metallomic analysis; nutrient; ICP-MS; ICP-OES; prevention; carcinogenesis
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Surfactant Sciences: Design, Synthesis, and Applications
edited by Zakaria Hafidi
submission deadline 20 Apr 2026 | Viewed by 170 | Submission Open
Keywords: surfactants; synthesis; biodegradation; catalysis; biological activity; nanoparticles; design; green chemistry; self-assembly; surface chemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Latest Molecular Research in Plant Secondary Metabolism
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 168 | Submission Open
Keywords: plants; plant in vitro systems; secondary metabolism; metabolite profiling and fingerprinting; sustainable production; elicitation; metabolic engineering; CRISPR/Cas; molecular targets
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Plant–Pathogen Interactions (4th Edition)
edited by
submission deadline 20 Apr 2026 | Viewed by 164 | Submission Open
Keywords: host; effection; pathogenicity; pathogen; plant immunity; interactions
(This special issue belongs to the Section Molecular Plant Sciences)
Latest Research on Probiotics: Molecular Mechanisms and Health Applications
edited by
submission deadline 20 Apr 2026 | Viewed by 164 | Submission Open
Keywords: probiotics; molecular signaling; microbial– host crosstalk; metabolomic profiling; microbiome modulation; metabolite– receptor interaction
(This special issue belongs to the Section Molecular Microbiology)
Pleiotropic NME Proteins: Nucleoside Diphosphate Kinases and Histidine-Protein Kinases submission deadline 20 Apr 2026 | Viewed by 161 | Submission Open
Keywords: NDPK  ; NME  ; NM23  ; AWD  ; protein-histidine kinase  ; cancer  ; metastasis  ; bioenergetics  ; cell signaling  ; cardiovascular diseases
(This special issue belongs to the Section Biochemistry)
Molecular Techniques to Study Food Safety Challenges submission deadline 20 Apr 2026 | Viewed by 155 | Submission Open
Keywords: food safety; hazards; foodborne pathogens; advanced microbial detection technologies; omics techniques; preventive measures
(This special issue belongs to the Section Molecular Microbiology)
Unraveling the Molecular Crosstalk Between Ferroptosis and Tumorigenesis
edited by
submission deadline 20 Apr 2026 | Viewed by 154 | Submission Open
Keywords: tumorigenesis; ferroptosis; cancer biology; tumor development
(This special issue belongs to the Section Molecular Oncology)
Antimicrobial Agents and the Quest for Resistance Breakthroughs
edited by
submission deadline 20 Apr 2026 | Viewed by 152 | Submission Open
Keywords: drug resistance; antimicrobial resistance (AMR); drug-resistant bacteria; drug-resistant viruses; drug-resistant fungi; drug-resistant parasite; drug resistance biomolecular studies; mechanism of resistance; novel antimicrobial agents; treatment of infectious diseases
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Research on Andrology
edited by Elikanah Olusayo Adegoke
submission deadline 20 Apr 2026 | Viewed by 150 | Submission Open
Keywords: fertilty; assisted reproduction technology; endocrine disrupting chemicals; hormones; male reproductive aging; semen analysis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanomedicine: Application of Nanostructured Biomaterials in the Biomedical Field
edited by
submission deadline 20 Apr 2026 | Viewed by 148 | Submission Open
Keywords: nanomedicine; nanostructured biomaterials; targeted drug delivery; tissue regeneration; biosensing
(This special issue belongs to the Section Molecular Nanoscience)
New Advances in Reversing Cancer Therapy Resistance
edited by
submission deadline 20 Apr 2026 | Viewed by 146 | Submission Open
Keywords: cancer; natural compound; cell death; radioresistance; chemoresistance
(This special issue belongs to the Section Molecular Pharmacology)
Novel Therapeutic Strategies and Targets in Rheumatoid Arthritis
edited by David Fox and
submission deadline 20 Apr 2026 | Viewed by 142 | Submission Open
Keywords: RA; synovium; FLS; synovial fluid; microbiome; autoimmunity; DMARD; joint inflammation; joint damage; nanoparticle
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Mitochondria-Associated Non-Coding RNAs
edited by , Jaime E. Villegas and
submission deadline 20 Apr 2026 | Viewed by 140 | Submission Open
Keywords: mitochondrial-encoded ncRNAs; mitochondrial miRNAs; mitochondrial lncRNAs; mitochondrial circRNAs; nuclear-encoded mitochondrial ncRNAs
(This special issue belongs to the Section Molecular Biology)
Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications
edited by
submission deadline 20 Apr 2026 | Viewed by 131 | Submission Open
Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging
(This special issue belongs to the Section Molecular Nanoscience)
Hydrogels and Nanogels: Revolutionizing Drug Delivery and Disease Detection
edited by Enrico Gallo
submission deadline 20 Apr 2026 | Viewed by 130 | Submission Open
Keywords: hydrogel and nanogel networks; supramolecular systems; hydrogel synthesis and analysis; nanogel preparation and characterization; nanostructured fibers; multiphase gels; biomedicine applications; supramolecular probes for imaging; hydrogels and nanogels as drug release systems; coatings and surface treatments; polymeric systems; peptide-based supramolecular systems
(This special issue belongs to the Section Materials Science)
Molecular Research in Leukemia
edited by Juan Manuel Mejia-Arangure
submission deadline 20 Apr 2026 | Viewed by 129 | Submission Open
Keywords: leukemia; molecular biology; genetic testing; epigenomics; targeted therapy; precision medicine; diagnostic techniques; molecular pathways
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Eco-Conscious Therapeutics: Molecular Foundations and Future Directions in Green Medicine
edited by and
submission deadline 20 Apr 2026 | Viewed by 128 | Submission Open
Keywords: green medicine; molecular therapeutics; sustainable healthcare; biomarker profiling; predictive toxicology; eco-friendly drug design; environmental impact; biodegradable materials
(This special issue belongs to the Section Molecular Toxicology)
Advances in Antimicrobial Agents and Resistance Mechanisms submission deadline 20 Apr 2026 | 1 articles | Viewed by 124 | Submission Open
Keywords: acquired resistance; antibiotic inactivation; antibiotic modifications; antibiotic uptake; antibiotics; antimicrobial agents; bacterial dormancy; efflux pumps; extrachromosomal elements; genomic mutations; novel antimicrobial molecules; resistant mechanisms
(This special issue belongs to the Section Molecular Microbiology)
Nano-Biomaterials for Biomedicine and Tissue Regeneration
edited by and
submission deadline 20 Apr 2026 | Viewed by 121 | Submission Open
Keywords: nanostructured biomaterials; cell-scaffold interactions; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Molecular Nanoscience)
Genome Editing in Autologous Stem Cells: From Bench to Bedside
edited by
submission deadline 20 Apr 2026 | Viewed by 120 | Submission Open
Keywords: genome editing; gene therapy; autologous transplant; preclinical studies; process development; scalability; quality control; manufacturing; regulatory compliance; IND-enabling studies
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Mechanisms and Pathways of Epithelial-Mesenchymal Transition
edited by
submission deadline 20 Apr 2026 | Viewed by 116 | Submission Open
Keywords: metastasis; fibrosis; tumor microenvironment; molecular pathways; EMT reversion
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Antimicrobial Nanoparticles
edited by and
submission deadline 20 Apr 2026 | Viewed by 115 | Submission Open
Keywords: antimicrobial nanoparticles; resistant pathogens; antimicrobial resistance; lipid nanoparticles; biomimetic nanostructures; combined therapy; antimicrobial strategies
(This special issue belongs to the Section Molecular Nanoscience)
Nanocomposite Fibers: Current Status and Applications
edited by
submission deadline 20 Apr 2026 | Viewed by 111 | Submission Open
Keywords: advanced fibrous and particulate materials; nano-enhanced textiles; natural fiber utilization; fiber quality; textile processing
(This special issue belongs to the Section Molecular Nanoscience)
Metal Toxicity and Particle Toxicity
edited by Alicja Piotrowska-Niczyporuk
submission deadline 20 Apr 2026 | Viewed by 106 | Submission Open
Keywords: metals; particles; toxicity; microplastic; environment pollution; animals; plants; algae
(This special issue belongs to the Section Molecular Toxicology)
Dynamic Nanoarchitectonics in Supramolecular Assemblies and Nanosystems: From Synthesis to Applications submission deadline 20 Apr 2026 | Viewed by 105 | Submission Open
Keywords: supramolecular chemistry; synthetic chemistry; nanoscale materials; nanostructured materials; molecular self-assembly; nanoparticles; nanotechnology
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Molecular Genetics of Head and Neck Cancer
edited by
submission deadline 20 Apr 2026 | Viewed by 104 | Submission Open
Keywords: head and neck cancer; molecular genetics; tumor heterogeneity; driver mutations; epigenetic alterations; non-coding RNAs; oncogenes and tumor suppressors; gene expression profiling; genomic instability; biomarkers for diagnosis and therapy
(This special issue belongs to the Section Molecular Oncology)
Biomaterials for Dental and Orthopedic Applications, 2nd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 73 | Submission Open
Keywords: personalized biomaterials; dental and orthopedic applications; tissue regeneration; 3D biorinting
(This special issue belongs to the Section Materials Science)
Tumor Markers and Tumor Microenvironment
edited by Tamás Micsik
submission deadline 20 Apr 2026 | Viewed by 69 | Submission Open
Keywords: tumor markers; tumor environment; molecular and genetics; omics; artificial intelligence; digital pathology; computational pathology; individualized therapy; prognostication
(This special issue belongs to the Section Molecular Oncology)
Epigenetic and Post-Transcriptional Regulation of Gene Expression
edited by Lidia Borkiewicz
submission deadline 20 Apr 2026 | Viewed by 68 | Submission Open
Keywords: epigenome; DNA methylation; chromatin remodeling; histone modifications; non-coding RNA; epitranscriptome; alternative splicing; RNA methylation; RNA edition
(This special issue belongs to the Section Molecular Biology)
Plant Responses to Abiotic and Biotic Stresses: 2nd Editon
edited by and
submission deadline 20 Apr 2026 | Viewed by 65 | Submission Open
Keywords: climate change and crop production; abiotic stress; biotic stress; plant resistance to abiotic and biotic stresses; molecular mechanism; physiological responses; plant hormones; carbohydrate metabolism and transport; molecular signaling; reactive oxygen species (ROS); calcium ions; photosynthesis; respiration; energy metabolism
(This special issue belongs to the Section Molecular Plant Sciences)
Latest Research on Drug-Diagnostics Co-Development in Oncology submission deadline 20 Apr 2026 | Viewed by 64 | Submission Open
Keywords: companion diagnostics; tumor; drug– diagnostic co-development; molecular profiling; biomarker; theranostics
(This special issue belongs to the Section Molecular Oncology)
Molecular Advances in Obstetrical and Gynaecological Disorders: 2nd Edition submission deadline 20 Apr 2026 | Viewed by 48 | Submission Open
Keywords: gynaecological disorders; obstetrical disorders; gynaecological diseases; genetic markers; molecular therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Research on Natural Compounds: Biosynthesis, Analysis, and Application submission deadline 20 Apr 2026 | Viewed by 47 | Submission Open
Keywords: phytochemicals; natural compounds; chromatography; MS; NMR; analysis; identification; extraction; standardisation; quantitation; activity; moleabular mechanism; biosynthesis
(This special issue belongs to the Section Biochemistry)
From Molecular Mechanisms to Precision Medicine in Gastrointestinal Cancers: (Epi)genetics, Pharmacogenomics, and Emerging Biomarkers submission deadline 20 Apr 2026 | Viewed by 45 | Submission Open
Keywords: gastrointestinal and colorectal cancer; genetic and epigenetic regulation; multi-omics and computational biology; molecular pathology and biomarker discovery; translational and precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Metalloproteinase, 2nd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 20 | Submission Open
Keywords: matrix metalloproteinases (MMPs); substrate specificity; pathological condition; metalloproteinases inhibitors
(This special issue belongs to the Section Biochemistry)
Biomolecular Stratification in Antiphospholipid Syndrome
edited by
submission deadline 20 Apr 2026 | Submission Open
Keywords: antiphospholipid syndrome; antiphospholipid; stratification; biomolecular; risk stratification; classification
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Triosephosphate Isomerase: Potential Target in Cancer Treatment and Other Diseases submission deadline 24 Apr 2026 | 1 articles | Viewed by 1294 | Submission Open
Keywords: cancer; glycolytic; triosephosphate isomerase; TPI; post-translational modification; cancer treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Food Allergens: Latest Molecular Advancements
edited by and
submission deadline 24 Apr 2026 | Viewed by 166 | Submission Open
Keywords: food allergies; allergen; allergenicity; epitope; desensitization; immunity reaction; hypoallergen; Ig E binding             TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in German   Translate to Simplified Chinese         Abkhazian Acehnese Acholi Afar Afrikaans Albanian Alur Amharic Arabic Armenian Assamese Avaric Awadhi Aymara Azerbaijani Balinese Baluchi Bambara Baoulé Bashkir Basque Batak Batak Simalungun Batak Toba Belarusian Bemba Bengali Betawi Bhojpuri Bikol Bosnian Breton Bulgarian Buryat Cantonese Catalan Cebuano Chamorro Chechen Chichewa Chuukese Chuvash Corsican Crimean Tatar Crimean Tatar (Latin) Croatian Czech Danish Dari Dinka Divehi Dogri Dombe Dutch Dyula Dzongkha English English (USA) Esperanto Estonian Ewe Faroese Fijian Filipino Finnish Fon French French (Canadian) Frisian Friulian Fulah Ga Galician Georgian German Greek Guarani Gujarati Haitian Creole Hakha Falam Hausa Hawaiian Hebrew Hiligaynon Hindi Hmong Hungarian Hunsrik Iban Icelandic Igbo Ilocano Indonesian Inuktitut Inuktitut (Latin) Irish Italian Jamaican Patois Japanese Javanese Jingpho Kalaallisut Kannada Kanuri Kapampangan Kazakh Khasi Khmer Kiga Kikongo Kinyarwanda Kokborok Komi Konkani (Latin) Korean Krio Kurdish (Kurmanji) Kurdish (Sorani) Kyrgyz Lao Latgalian Latin Latvian Ligurian Limburgish Lingala Lithuanian Lombard Luganda Luo Luxembourgish Macedonian Madurese Maithili Makassarese Malagasy Malay Malay (Arabic) Malayalam Maltese Mam Manx Maori Marathi Mari Marshallese Marwari Mauritian Creole Meitei/Meetei (Mayek) Minangkabau Mizo Mongolian Myanmar (Burmese) N'Ko Bambara Nahuatl Ndau (Zimbabwe) Ndebele Nepali Newari Northern Sami Norwegian Nuer Occitan Odia Oromo Ossetian Pangasinan Papiamento Pashto Persian Polish Portuguese Portuguese (Portugal) Punjabi Punjabi (Arabic) Q'eqchi' Quechua Romani Romanian Rundi Russian Samoan Sango Sanskrit Santali Santali (Latin) Scots Gaelic Sepedi Serbian Sesotho Seychellois Creole Shan Shona Sicilian Silesian Simplified Chinese Sindhi Sinhala Slovak Slovenian Somali Spanish Sundanese Susu Swahili Swati Swedish Tahitian Tajik Tamazight Tamazight (Latin) Tamil Tatar Telugu Tetum Thai Tibetan Tigrinya Tiv Tok Pisin Tongan Traditional Chinese Tshiluba Tsonga Tswana Tulu Tumbuka Turkish Turkmen Tuvan Twi Udmurt Ukrainian Urdu Uyghur Uzbek Venda Venetian Vietnamese Waray Welsh Wolof Xhosa Yakut Yiddish Yoruba Yucatec Maya Zapotec Zulu   Always translate German to Simplified Chinese Never translate German Never translate admin.mdpi.com
(This special issue belongs to the Section Molecular Biology)
Identification of Predictive Molecular Markers for Cancer Progression, Response to Therapy, and Disease Outcome
edited by
submission deadline 25 Apr 2026 | Viewed by 220 | Submission Open
Keywords: predictive biomarkers; cancer progression; therapy response; molecular signatures; precision oncology
(This special issue belongs to the Section Molecular Oncology)
Innovations in Functional Biomaterials for Biomedical Applications
edited by
submission deadline 25 Apr 2026 | Viewed by 112 | Submission Open
Keywords: functional biomaterials; molecular mechanisms; drug delivery systems; tissue engineering; biointerface interactions; smart/stimuli-responsive materials; molecular modeling and simulation; gene and protein expression; biomolecular characterization; regenerative medicine
(This special issue belongs to the Section Materials Science)
Nanomaterials and Regulated Cell Death Pathways: Novel Therapeutic Opportunities
edited by
submission deadline 25 Apr 2026 | Viewed by 93 | Submission Open
Keywords: apoptosis; ferroptosis; nanotherapy; nanotoxicity; necroptosis; oxidative stress; PANoptosis; pyroptosis; regulated cell death
(This special issue belongs to the Section Molecular Nanoscience)
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