Epigenetic and Post-Transcriptional Regulation of Gene Expression

Dear Colleagues,

Regulation of gene expression is a multilayered process that occurs at the chromatin, transcriptional, post-transcriptional, and post-translational levels. Many molecular mechanisms of epigenetic modulation—including DNA methylation, chromatin remodeling and histone modification, regulation by non-coding RNA, as well as post-transcriptional processes such as alternative splicing, RNA methylation and pseudouridylation, RNA editing, and regulation by microRNA—have been extensively investigated. With the wealth of information now available, it has become clear that these mechanisms can be harvested as tools to modulate gene expression for therapeutic purposes without altering the genome itself.

This Special Issue aims highlights the latest advances in our understanding of the molecular basis of epigenetic and epitranscriptomic regulation across multiple RNA species, including mRNA various ncRNAs such as rRNA and tRNA. The focus is on innovative research uncovering the discovery and function of key regulatory players and their applications in cell and developmental biology, stem cell research, tissue engineering, physiology, neuroscience, immunology, oncology, and therapeutics. We invite the submission of original research articles, reviews, and short communications.

Dr. Lidia Borkiewicz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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