Advances in Antimicrobial Agents and Resistance Mechanisms
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 October 2025 | Viewed by 37
Special Issue Editor
Interests: antimicrobial activity; medicinal plants; synthetic compounds; bioguided evaluation; drug resistant mechanisms; immunology; infectious diseases; antimycobacterial compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antimicrobial resistance is widely recognized as one of the most important public health threats of our time. Projections estimate that by 2050, nearly 10 million people may die due to the failure of existing treatments and the increasing spread of resistant pathogens.
Understanding the molecular mechanisms that confer antimicrobial resistance is essential for improving therapeutic strategies, preventing resistance emergence, and guiding the development of novel antimicrobial agents. Resistance mechanisms vary widely and may include impaired antibiotic uptake, enzymatic inactivation of antibiotic, alterations in drug targets due to genomic mutations, decreased microbial metabolism, and antibiotic expulsion via efflux pumps. These mechanisms may be intrinsic to microorganisms or acquired through extrachromosomal elements.
This Special Issue aims to present recent insights into the molecular basis of antimicrobial resistance. We welcome original research articles and comprehensive reviews that address advances in the understanding of resistance mechanisms, as well as the development and evaluation of innovative antimicrobial compounds.
Prof. Dr. Julieta Luna-Herrera
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- acquired resistance
- antibiotic inactivation
- antibiotic modifications
- antibiotic uptake
- antibiotics
- antimicrobial agents
- bacterial dormancy
- efflux pumps
- extrachromosomal elements
- genomic mutations
- novel antimicrobial molecules
- resistant mechanisms
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