Latest Research on Probiotics: Molecular Mechanisms and Health Applications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 20
Special Issue Editor
Special Issue Information
Dear Colleagues,
Probiotics have emerged as pivotal modulators of host–microbe interactions, with their health benefits extending beyond gastrointestinal homeostasis to systemic immune regulation and metabolic balance. While clinical applications of probiotics are well-documented, understanding their molecular mechanisms remains a frontier in microbiological research. This Special Issue aims to dissect the molecular underpinnings of probiotic functionality, emphasizing mechanistic insights into microbial signaling, host–microbe crosstalk, and microbiome modulation. In this context, this Special Issue, “Latest Research on Probiotics: Molecular Mechanisms and Health Applications”, will cover a selection of current research topics, including, but not limited to, the following:
- Molecular signaling mechanisms between probiotics and host cells and their impact on metabolic regulation.
- Omics-driven insights into probiotic metabolism, such as genomic, transcriptomic, and metabolomic analyses of probiotic strains under varying physiological conditions.
- Mechanisms of interaction between probiotic metabolites (e.g., short-chainfatty acids, indole derivatives) and host receptors.
This issue will focus on molecular discoveries and link them to translational potential as we seek to advance the design of next-generation probiotics tailored for precision health interventions.
Mr. Haichuan Li is the Guest Editor Assistant, who will help manage this Special Issue.
Prof. Dr. Ying Zhang
Guest Editor
Manuscript Submission Information
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Keywords
- probiotics
- molecular signaling
- microbial–host crosstalk
- metabolomic profiling
- microbiome modulation
- metabolite–receptor interaction
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