Unraveling the Molecular Crosstalk Between Ferroptosis and Tumorigenesis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 9
Special Issue Editor
Interests: ferroptosis; p53; cancer metabolism; natural compound
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Tumorigenesis involves a complex network of molecular events that drive the initiation, progression, and metastasis of cancer. In recent years, the discovery of novel mechanisms such as ferroptosis—an iron-dependent form of regulated cell death—has significantly advanced our understanding of cancer biology. This special issue welcomes both original research articles and review papers focusing on emerging cell death pathways such as ferroptosis, as well as studies investigating how the expression of novel tumor-related genes influences tumor development. We particularly encourage submissions that explore the identification of newly expressed genes and regulatory networks in tumors, utilizing cutting-edge technologies such as genome-wide screening, single-cell transcriptomics, and integrative bioinformatics. Studies that reveal key molecular determinants of tumor cell sensitivity or resistance to ferroptosis, and those that propose novel diagnostic or therapeutic applications based on these findings, are highly welcomed. By highlighting recent advancements across various cancer types, this special issue aims to serve as a valuable resource for researchers and clinicians seeking a deeper molecular understanding of tumorigenesis. We look forward to your contributions.
Thank you.
Best regards,
Dr. Ji Hoon Jung
Guest Editor
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Keywords
- tumorigenesis
- ferroptosis
- cancer biology
- tumor development
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