Molecular Research on Andrology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 15
Special Issue Editor
Special Issue Information
Dear Colleagues,
Male fertility is a critical component of human reproduction, yet it is often overshadowed by the more intensive study of the female reproductive study. Recent decades have seen a growing recognition of male factors as central contributors to infertility, accounting for nearly 50% of all infertility cases. Male fertility is influenced by a complex interplay of genetic, physiological, environmental, and lifestyle factors. While intrinsic factors such as hormonal imbalances, genetic abnormalities, and testicular dysfunctions have long been studied, there is growing concern over the impact of extrinsic influences—especially environmental exposures—on male reproductive health.
The integration of molecular biology techniques into andrology allows researchers to conduct investigations, assessing parameters such as DNA fragmentation, oxidative stress, epigenetic modifications, and transcriptomic and proteomic profiles. These advances are reshaping the diagnostic and therapeutic landscape of male infertility, providing novel biomarkers and potential targets for intervention against declining male fertility and impaired male reproductive potential globally.
This research topic welcomes the submission of original research, reviews, mini-reviews, and systematic reviews that explore a wide range of topics including, but not limited to, the following areas:
- Assisted reproductive technology.
- Interplay of genetic, physiological, and environmental factors on male fertility.
- Biomarkers and therapeutic target.
- Extrinsic and intrinsic factors promoting male infertility.
Dr. Elikanah Olusayo Adegoke
Guest Editor
Manuscript Submission Information
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Keywords
- fertilty
- assisted reproduction technology
- endocrine disrupting chemicals
- hormones
- male reproductive aging
- semen analysis
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