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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Advances of Layered Double Hydroxides (LDH) for Corrosion Protection

edited by

Henryk Kania

submission deadline 20 Feb 2026 | Viewed by 188 | Submission Open

Keywords: layered double hydroxide (LDHs); corrosion resistance; coatings; corrosion products

(This special issue belongs to the Section Materials Science)

From Pathogenic Mechanisms to Therapy in Retinal Diseases

edited by

Nan-Kai Wang

and

Eugene Yu Chuan Kang

submission deadline 20 Feb 2026 | Viewed by 182 | Submission Open

Keywords: retinal degeneration; oxidative stress; angiogenesis; mitochondria; cellular metabolism; genetic disorders and gene therapy; genes; age-related macular degeneration; inherited retinal dystrophy; diabetic retinopathy; retinal ganglion cells; photoreceptors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets

edited by Uchenna John Unachukwu

submission deadline 20 Feb 2026 | Viewed by 177 | Submission Open

Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Antiviral Agents and Antiviral Therapy

edited by

Jesus Alberto Silvas

submission deadline 20 Feb 2026 | Viewed by 177 | Submission Open

Keywords: therapeutics; high-throughput screening; viral reverse genetics; luciferase; fluorescent; compound; repurpose; antiviral; diagnostics

(This special issue belongs to the Section Molecular Immunology)

Nutrition from Cereal Foods: Molecular Insights into Nutrition, Metabolism and Health Regulation

edited by Genyi Zhang

submission deadline 20 Feb 2026 | Viewed by 177 | Submission Open

Keywords: molecular breeding; cereal crops; bioactive compounds; metabolic syndrome; inflammation; gut health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Natural Compounds in Cancer: Targeting Immune Cells and Signalling Pathways

edited by

Tomasz Jędrzejewski

submission deadline 20 Feb 2026 | Viewed by 172 | Submission Open

Keywords: natural compounds; cancer; inflammation; signalling pathways; antineoplastic agents; macrophage; T cells; molecular mechanism of pharmacological action; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Age-Dependence of Neuroimmune Reactions

edited by

Babak Baban

submission deadline 20 Feb 2026 | Viewed by 172 | Submission Open

Keywords: age; neuroimmune dynamics; neuroimmune interaction; immune system; the central nervous system; age-related neuroinflammation; neurodegenerative diseases

(This special issue belongs to the Section Molecular Immunology)

Electrochemistry and Emerging Contaminants: Molecular Insights for Innovative Solutions

edited by

Miguel A. Esteso

submission deadline 20 Feb 2026 | Viewed by 165 | Submission Open

Keywords: electrochemistry; chemical reactions; removal; environmental pollution

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Plasticity in Multiple Sclerosis: From Molecular to System Level, from Adaptation to Maladaptation

edited by Gloria Dalla Costa and Laura Cacciaguerra

submission deadline 20 Feb 2026 | Viewed by 161 | Submission Open

Keywords: multiple sclerosis; neuroplasticity; remyelination; synaptic adaptations

(This special issue belongs to the Section Molecular Neurobiology)

Bioactive Lipid Metabolites in Age-Related Comorbidities: From Mechanisms to Therapeutics

edited by

Sadanand Fulzele

submission deadline 20 Feb 2026 | Viewed by 152 | Submission Open

Keywords: lipid metabolites; aging; sarcopenia; osteoporosis; osteoarthritis

(This special issue belongs to the Section Biochemistry)

Transcriptional Regulation and Its Misregulation in Human Diseases: Recent Insights

edited by

Amelia Casamassimi

and

Monica Rienzo

submission deadline 20 Feb 2026 | Viewed by 147 | Submission Open

Keywords: transcription machinery; transcription (co)factors; chromatin regulators; splicing regulators; noncoding RNAs; transcription misregulation; genetic alterations; human diseases; transcriptome profiling; bioinformatics analysis

(This special issue belongs to the Section Molecular Biology)

The Impact of the Immune System on the Tumor Microenvironment: Relevance to Glioma Development

edited by Gabriela Verónica Salamone

submission deadline 20 Feb 2026 | Viewed by 141 | Submission Open

Keywords: gliomas tumor microenvironment immune

(This special issue belongs to the Section Molecular Oncology)

Recent Research in Nanoelectrochemistry

edited by

Ioan Baldea

submission deadline 20 Feb 2026 | Viewed by 138 | Submission Open

Keywords: nanoelectrochemistry; single-entity electrochemistry; nanoscale imaging; molecular electronics devices; nanostructured electrodes; electrochemical sensors; energy storage; catalysis; biomedical applications

(This special issue belongs to the Section Materials Science)

Advancements in the Electrochemical Detection of Biomolecules: From Sensing to Environmental Applications

edited by

Habibulla Imran

submission deadline 20 Feb 2026 | Viewed by 137 | Submission Open

Keywords: biomolecules; nanomaterials; biorecognition; biomolecular detection; electrochemical

(This special issue belongs to the Section Molecular Biophysics)

Molecular Progress in Male Reproduction

edited by

Ahmet Ayaz

submission deadline 20 Feb 2026 | Viewed by 131 | Submission Open

Keywords: male infertility; spermatogenesis; epigenetics; sperm function; testicular molecular biology; bioinformatics; reproductive genomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Fungal Genetics and Functional Genomics Research

edited by

Yuqi Qin

and

Jian Zhao

submission deadline 20 Feb 2026 | Viewed by 114 | Submission Open

Keywords: enzymes; fungal genetics; fungi; gene editing; regulation; secondary metabolites; synthetic biology; transcription

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Advances in Gestational Diabetes Mellitus: 2nd Edition

edited by Natasha Singh

submission deadline 20 Feb 2026 | Viewed by 110 | Submission Open

Keywords: metabolome; placental insulin signaling; DNA methylation; mitochondrial oxidation; MTOR; amino acids lipidomics; proteomics; gluconeogenesis; GDM

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Abiotic Stress in Plants, 2nd Edition

edited by

Xiujun Zhang

submission deadline 20 Feb 2026 | 1 articles | Viewed by 107 | Submission Open

Keywords: abiotic stress; ROS; redox; antioxidants; phytohormones; ethylene; plant stress eco-physiology

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biology of the Thyroid Cancer and Thyroid Dysfunctions: 2nd Edition

edited by Vija Lavinia

submission deadline 20 Feb 2026 | Viewed by 102 | Submission Open

Keywords: animal models; apoptosis; autophagy; cancer biomarker; cancer epidemiology; cancer prevention; cancer screening; cholesterol metabolism; clinical trial; DNA repair; epigenomics; genome instability; genomic database; genomics; invasion; metabolomics; metastasis; methylation; microarray; microRNA; molecular diagnostics; molecular tumor pathology; next-generation sequencing; noncoding RNA; omics; personalized medicine; prognosis; proteomics; radionuclide therapy; signaling pathway; SNP genotyping; targeted therapy; theranostics; thyroid cancer; hyperthyroidism; therapeutic targets; translational cancer research; treatment response; tumor microenvironment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biophysical Studies of Protein Structure-Function Relationships

edited by

Almerinda Di Venere

Giampiero Mei

and Velia Minicozzi

submission deadline 20 Feb 2026 | Viewed by 87 | Submission Open

Keywords: protein structure; molecular dynamics; computational modeling; drug discovery

(This special issue belongs to the Section Molecular Biophysics)

Decoding Protein Structure and Protein Dynamics in Cancer

edited by

Umesh Kalathiya

and

Monikaben Padariya

submission deadline 20 Feb 2026 | Viewed by 84 | Submission Open

Keywords: protein structures; oncogenes; post-translational modifications (PTMs); cancer; proteomics; computational biology; structural biology; molecular modeling; bioinformatics

(This special issue belongs to the Section Molecular Biology)

Molecular Pathogenesis and Treatment Approaches of Hematological Malignancies

edited by

Yosuke Minami

submission deadline 20 Feb 2026 | Viewed by 83 | Submission Open

Keywords: leukemia; lymphoma; minimal residual disease (MRD); cancer genomic profiling (CGP); molecular targeted therapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Progress of Cardiovascular and Metabolic Disease

edited by

Ilenia Calcaterra

submission deadline 20 Feb 2026 | Viewed by 83 | Submission Open

Keywords: cardiometabolic continuum; endothelial dysfunction; heart failure; metabolic complications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Genetic and Epigenetic Research in Skin Diseases

edited by

Nikolai Pace

submission deadline 20 Feb 2026 | Viewed by 58 | Submission Open

Keywords: skin diseases; genodermatoses; psoriasis; atopic dermatitis; hidradenitis; suppurativa; epigenetic regulation; genome-wide association studies (GWAS); next-generation sequencing; translational dermatogenomics; Mendelian randomization; rare disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of the Mitochondria in Human Health and Diseases

edited by

María Isabel Hernández-Alvarez

submission deadline 25 Feb 2026 | 2 articles | Viewed by 13381 | Submission Open

Keywords: mitochondria; mitochondria contact sites; metabolism; lipids; metabolites

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Cell Proliferation, Senescence and Apoptosis

edited by

Chuanxi Cai

submission deadline 25 Feb 2026 | 3 articles | Viewed by 7553 | Submission Open

Keywords: biological molecules; cell proliferation; senescence; apoptosis; human diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Human Retrovirus Infection: 2nd Edition

edited by

Yosuke Maeda

Toshio Hattori

and Kotaro Shirakawa

submission deadline 25 Feb 2026 | 3 articles | Viewed by 7540 | Submission Open

Keywords: retrovirus; ATL; HIV-1; AIDS

(This special issue belongs to the Section Molecular Microbiology)

Molecular Research on Skin Inflammation

edited by

Nabiha Yusuf

submission deadline 25 Feb 2026 | 4 articles | Viewed by 7478 | Submission Open

Keywords: skin inflammation; molecular diagnosis; dermatitis; molecular pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Multifunctional Nanocomposites for Bioapplications

edited by

Athina Angelopoulou

submission deadline 25 Feb 2026 | 5 articles | Viewed by 7421 | Submission Open

Keywords: nanocomposites; biomedical applications; molecular characteristics; metabolic pathways; biomarkers; external stimuli

(This special issue belongs to the Section Molecular Nanoscience)

Advancements in Host-Directed Antiviral Therapies

edited by

Raquel Bello-Morales

submission deadline 25 Feb 2026 | 1 articles | Viewed by 6795 | Submission Open

Keywords: antiviral drugs; drug discovery; host cell targets; HIV; HCV; influenza; SARS-CoV-2

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Interactions of Microbiome in Skin, Gastrointestinal, and Mucocutaneous Diseases

edited by Capercomorin S. Pitchumoni and

Bijan Safai

submission deadline 25 Feb 2026 | 2 articles | Viewed by 6714 | Submission Open

Keywords: human microbiome; immune system; skin disease; gut– skin axis; gut flora; microbe-host interactions; microbial metabolites; dysbiosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Understanding Aging in Health and Disease

edited by

Laura Cianfruglia

submission deadline 25 Feb 2026 | 2 articles | Viewed by 6141 | Submission Open

Keywords: immunosenescence; age-related disease; ageing; oxidative stress; inflammaging

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Forensic Toxicology: Innovative Approaches in Detection of New Psychoactive Substances

edited by Roberta Tittarelli and Giulio Mannocchi

submission deadline 25 Feb 2026 | 2 articles | Viewed by 5750 | Submission Open

Keywords: addiction; new psychoactive substances; mass spectrometry; biological matrices; diversion; forensic toxicology; drug testing

(This special issue belongs to the Section Molecular Toxicology)

Reproductive Genetics and Epigenetics: Insights into Infertility Failures and Treatment Pathways

edited by

Hossam H. Shawki

submission deadline 25 Feb 2026 | 3 articles | Viewed by 5576 | Submission Open

Keywords: infertility; epigenetics; polymorphism; gametogenesis; fertilization; embryo development; reproductive organs; congenital malformations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advancements in Understanding Protein Misfolding Disorders and Cancer

edited by

Marijn Speeckaert

submission deadline 25 Feb 2026 | 2 articles | Viewed by 4768 | Submission Open

Keywords: protein misfolding; cancer; amyloidosis

(This special issue belongs to the Section Molecular Oncology)

Peptide Self-Assembly

edited by

Yi Jia

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4515 | Submission Open

Keywords: peptide assembly; aromatic short peptides; bioinspired supramolecular architectures; functional materials; peptide microfabrication; anticancer therapy; supercapacitor; biosensing

(This special issue belongs to the Section Macromolecules)

Molecular Advances in Electrochemical Materials

edited by

Raj Karthik

submission deadline 25 Feb 2026 | 2 articles | Viewed by 4384 | Submission Open

Keywords: electrochemical materials; molecular design; energy storage; electrocatalysis; sensing applications; nanomaterials; sustainable materials; hybrid systems; interface engineering; green chemistry

(This special issue belongs to the Section Materials Science)

From Macrophage Biology to Cell and EV-Based Immunotherapies

edited by

Katarzyna Nazimek

and

Krzysztof Bryniarski

submission deadline 25 Feb 2026 | 2 articles | Viewed by 4383 | Submission Open

Keywords: macrophage-based; macrophage-targeting; cancer immunotherapies; autoimmunity

(This special issue belongs to the Section Molecular Immunology)

Chemistry Triggered by Low-Energy Particles

edited by Hassan Abdoul-Carime

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4180 | Submission Open

Keywords: low energy (< 50 eV); photons; electrons; ions; gas phase; single molecules; clusters; condensed phase liquids and films; experimental techniques; density functional theory; IA-based prediction models

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Heart Failure Risk Factors and Therapies on a Molecular Basis

edited by

Tomasz Urbanowicz

submission deadline 25 Feb 2026 | 2 articles | Viewed by 3840 | Submission Open

Keywords: heart failure; risk factors; inflammatory; neutrophils; cytokines; pharmacological; therapies; molecular-based processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Mechanisms of Cardiovascular Repair

edited by

Isotta Chimenti

submission deadline 25 Feb 2026 | 3 articles | Viewed by 3755 | Submission Open

Keywords: fibroblasts; injury repair; cardiac scar; extracellular matrix; fibrosis; angiogenesis; inflammation; cardioprotection

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Phytochemical Dynamics: Plant Metabolite Responses to Environmental Factors

edited by

Ivana Sola

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2899 | Submission Open

Keywords: plant metabolites; phytochemicals; biotic and abiotic factors; environmental influences; biochemical pathways; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Advances and Current Challenges in Plasma Medicine

edited by

Andrei Vasile Nastuta

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2793 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy; plasma and food; plasma and automotive; plasma and aerospace; plasma diagnostics; plasma material processing; plasma polymerization and coating; simulation of plasma phenomena during interaction with matter

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cell Fate Decisions: Autophagy, Apoptosis, Pyroptosis, Necroptosis, Ferroptosis and PANoptosis in Health and Disease

edited by

Yaqiu Wang

submission deadline 25 Feb 2026 | 1 articles | Viewed by 2201 | Submission Open

Keywords: inflammation; autophagy; apoptosis; pyroptosis; necroptosis; PANoptosis; ferroptosis; cell death; cell survival

(This special issue belongs to the Section Molecular Biology)

Immune Regulation in Lung Diseases

edited by

Chiara Colarusso

and

Rosalinda Sorrentino

submission deadline 25 Feb 2026 | 3 articles | Viewed by 1835 | Submission Open

Keywords: lung disease; immune system; lung immune cells; lung epithelial cells; therapy

(This special issue belongs to the Section Molecular Immunology)

Heavy Metal Exposure on Health

edited by

Rosanna Mallamaci

submission deadline 25 Feb 2026 | 2 articles | Viewed by 1829 | Submission Open

Keywords: heavy metals; toxic metal exposure; oxidative stress; mitochondrial dysfunction; epigenetic alterations; physiological and molecular pathways of cellular toxicology; biomarkers of toxicity; chelating agents; antioxidants; therapies or treatments

(This special issue belongs to the Section Molecular Toxicology)

The Regulation of Microorganisms on Human Endocrine and Metabolic Systems

edited by Thi Phuong Nam Bui and Valentina Tremaroli

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1044 | Submission Open

Keywords: human gut microbiome; endocrine signaling; metabolism; obesity; type 2 diabetes; cardiometabolic diseases

(This special issue belongs to the Section Molecular Microbiology)

Extracellular Vesicles: Functions and Therapeutic Applications

edited by Deepshikha Tewari

submission deadline 25 Feb 2026 | Viewed by 935 | Submission Open

Keywords: extracellular vesicles; exosome; cell-to-cell communication; diagnosis; treatment; molecular markers; diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanism and Pathogenesis of Neuroinflammation in Neurological Disorders

edited by

Masashi Tanaka

submission deadline 25 Feb 2026 | Viewed by 517 | Submission Open

Keywords: age-related disorders; Alzheimer’ s disease; amyloid-β ; bioactive molecules; cognitive impairment; dementia; glial activation; microglia; neuroinflammation; neurological disorders; neurotherapeutics; tau hyperphosphorylation

(This special issue belongs to the Section Molecular Neurobiology)

New Insights into Molecular Mechanisms of Chronic Kidney Disease

edited by

Lǎcrǎmioara Ionela Butnariu

submission deadline 25 Feb 2026 | Viewed by 471 | Submission Open

Keywords: chronic kidney disease; molecular mechanism; signaling pathways; endothelial dysfunction; inflammation; genetic variants; epigenetics; oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1601-1650 on page 33 of 66.

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