Natural Compounds in Cancer: Targeting Immune Cells and Signalling Pathways
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 July 2025 | Viewed by 79
Special Issue Editor
Interests: bioactive compounds; antineoplastic agents; macrophage phenotype; fever; cell culture; in vivo studies
Special Issue Information
Dear Colleagues,
Natural bioactive compounds from plants, fungi, and marine organisms show great potential in regulating immune responses and targeting oncogenic pathways. Dysregulated signalling in cancer and immune cells drives tumour initiation and development, highlighting the urgent need for innovative therapies. With high specificity and lower toxicity than conventional treatments, natural compounds offer a promising avenue for modulating these critical pathways.
This Special Issue aims to explore the potential of natural compounds in cancer modulation by selectively targeting immune cells, cancer cells, and key signalling pathways. It covers a broad range of topics, including the anti-inflammatory and anti-cancer mechanisms of these compounds, their role in immunomodulation, and their influence on the tumour microenvironment, including the crosstalk between immune and cancer cells. Additionally, it highlights novel strategies for discovering and developing bioactive compounds and their synergistic effects with conventional chemotherapeutic agents.
In this Special Issue, original research articles and reviews are welcome.
I look forward to receiving your contributions.
Dr. Tomasz Jędrzejewski
Guest Editor
Manuscript Submission Information
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Keywords
- natural compounds
- cancer
- inflammation
- signalling pathways
- antineoplastic agents
- macrophage
- T cells
- molecular mechanism of pharmacological action
- immunotherapy
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